CH624949A5 - - Google Patents
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- Publication number
- CH624949A5 CH624949A5 CH865776A CH865776A CH624949A5 CH 624949 A5 CH624949 A5 CH 624949A5 CH 865776 A CH865776 A CH 865776A CH 865776 A CH865776 A CH 865776A CH 624949 A5 CH624949 A5 CH 624949A5
- Authority
- CH
- Switzerland
- Prior art keywords
- methyl
- carboxylic acid
- dihydro
- benzofuran
- dichloro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/011,651 US4254600A (en) | 1976-01-22 | 1979-02-12 | Mounting for detachably connecting wall panels and the like |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59483975A | 1975-07-09 | 1975-07-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH624949A5 true CH624949A5 (fr) | 1981-08-31 |
Family
ID=24380621
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH865776A CH624949A5 (fr) | 1975-07-09 | 1976-07-06 |
Country Status (14)
Country | Link |
---|---|
US (2) | US4087542A (fr) |
JP (1) | JPS5210261A (fr) |
AU (1) | AU505135B2 (fr) |
BE (1) | BE843644A (fr) |
CH (1) | CH624949A5 (fr) |
DE (1) | DE2630800A1 (fr) |
DK (1) | DK282076A (fr) |
ES (1) | ES449389A1 (fr) |
FR (1) | FR2316934A1 (fr) |
GB (1) | GB1511427A (fr) |
HU (1) | HU176564B (fr) |
NL (1) | NL7606908A (fr) |
SE (1) | SE7607157L (fr) |
ZA (1) | ZA764080B (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4100294A (en) | 1976-12-06 | 1978-07-11 | Merck & Co., Inc. | 5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives |
US4205080A (en) * | 1977-07-21 | 1980-05-27 | Shell Oil Company | 2,3-Dihydro benzofuran carboxamides |
US4189496A (en) * | 1978-02-16 | 1980-02-19 | Merck & Co., Inc. | 2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid |
EP0019955A1 (fr) * | 1979-05-16 | 1980-12-10 | Shell Internationale Researchmaatschappij B.V. | Dérivés d'acide benzofuranne-carboxylique, leur préparation et leur utilisation dans des compositions inhibant la lipogenèse |
US4237130A (en) * | 1979-06-21 | 1980-12-02 | Merck & Co., Inc. | 2,3-Dihydro-6,7-disubstituted-5-(substituted sulfonyl)benzofuran-2-carboxylic acids |
US4237144A (en) * | 1979-06-21 | 1980-12-02 | Merck & Co., Inc. | 2,3-Dihydro-2,6,7-trisubstituted-5-acylbenzofurans |
JPS5737737A (en) * | 1980-08-15 | 1982-03-02 | Fuji Photo Film Co Ltd | Magnetic recording medium |
US4510322A (en) * | 1981-07-13 | 1985-04-09 | Merck & Co., Inc. | Indacrinone having enhanced uricosuric |
NZ200641A (en) * | 1981-07-13 | 1985-12-13 | Merck & Co Inc | Pharmaceutical compositions containing(+)and(-)enantiomers of indacrinone |
US4435422A (en) * | 1982-09-15 | 1984-03-06 | Abbott Laboratories | 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions |
JPS5973579A (ja) * | 1982-10-19 | 1984-04-25 | Kotobuki Seiyaku Kk | ベンゾフラン又はベンゾチオフェン誘導体,この化合物を有効成分とする尿酸排泄剤及びその製造方法 |
EP0117675B1 (fr) * | 1983-02-19 | 1986-07-23 | Beecham Group Plc | Dérivés d'acide benzofuranne- et benzothiophène carboxylique |
US4578509A (en) * | 1983-04-01 | 1986-03-25 | Merck & Co., Inc. | Process for preparing a manipulated enantiomer mixture by asymmetric chiral phase transfer catalysis |
DE3317884A1 (de) * | 1983-05-17 | 1984-11-22 | Hoechst Ag, 6230 Frankfurt | 5-(4-chlor-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarbonsaeuren und verfahren zu ihrer herstellung |
US4654365A (en) * | 1985-09-26 | 1987-03-31 | Merck & Co., Inc. | 2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, and their salts useful in the treatment of brain injury |
US6858615B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
US6858614B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenolic guanidine sodium channel blockers |
US6903105B2 (en) * | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
US20050090505A1 (en) * | 2003-08-18 | 2005-04-28 | Johnson Michael R. | Methods of reducing risk of infection from pathogens |
US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
GEP20186903B (en) | 2012-12-17 | 2018-10-25 | Saiensis Ink Perion | Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration |
MX2015007797A (es) | 2012-12-17 | 2015-10-05 | Parion Sciences Inc | Compuestos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil) carbamimidoil) pirazin-2-carboxamida. |
US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH508615A (de) * | 1968-05-30 | 1971-06-15 | Ciba Geigy Ag | Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren |
FR2201883B1 (fr) * | 1972-10-05 | 1975-10-31 | Roussel Uclaf |
-
1976
- 1976-04-20 US US05/678,529 patent/US4087542A/en not_active Expired - Lifetime
- 1976-06-22 SE SE7607157A patent/SE7607157L/xx not_active Application Discontinuation
- 1976-06-23 DK DK282076A patent/DK282076A/da unknown
- 1976-06-24 NL NL7606908A patent/NL7606908A/xx not_active Application Discontinuation
- 1976-06-29 AU AU15404/76A patent/AU505135B2/en not_active Expired
- 1976-06-30 BE BE168519A patent/BE843644A/fr unknown
- 1976-06-30 ES ES449389A patent/ES449389A1/es not_active Expired
- 1976-07-06 GB GB28088/76A patent/GB1511427A/en not_active Expired
- 1976-07-06 CH CH865776A patent/CH624949A5/de not_active IP Right Cessation
- 1976-07-07 FR FR7620735A patent/FR2316934A1/fr active Granted
- 1976-07-08 ZA ZA00764080A patent/ZA764080B/xx unknown
- 1976-07-08 DE DE19762630800 patent/DE2630800A1/de not_active Withdrawn
- 1976-07-09 JP JP51081104A patent/JPS5210261A/ja active Pending
- 1976-07-09 HU HU76ME2002A patent/HU176564B/hu unknown
-
1978
- 1978-01-27 US US05/873,023 patent/US4163794A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FR2316934A1 (fr) | 1977-02-04 |
JPS5210261A (en) | 1977-01-26 |
BE843644A (fr) | 1976-12-30 |
NL7606908A (nl) | 1977-01-11 |
HU176564B (en) | 1981-03-28 |
US4163794A (en) | 1979-08-07 |
GB1511427A (en) | 1978-05-17 |
DK282076A (da) | 1977-01-10 |
AU505135B2 (en) | 1979-11-08 |
ES449389A1 (es) | 1977-12-16 |
US4087542A (en) | 1978-05-02 |
FR2316934B1 (fr) | 1979-07-20 |
ZA764080B (en) | 1978-02-22 |
AU1540476A (en) | 1978-01-05 |
SE7607157L (sv) | 1977-01-10 |
DE2630800A1 (de) | 1977-01-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |