CH624431A5 - - Google Patents

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Publication number
CH624431A5
CH624431A5 CH1053575A CH1053575A CH624431A5 CH 624431 A5 CH624431 A5 CH 624431A5 CH 1053575 A CH1053575 A CH 1053575A CH 1053575 A CH1053575 A CH 1053575A CH 624431 A5 CH624431 A5 CH 624431A5
Authority
CH
Switzerland
Prior art keywords
enzyme
solution
activity
aqueous
polymeric carrier
Prior art date
Application number
CH1053575A
Other languages
German (de)
English (en)
Inventor
Richard Antony Godwin Smith
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of CH624431A5 publication Critical patent/CH624431A5/de

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/06—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing polymers
    • B01J31/061—Chiral polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/003—Catalysts comprising hydrides, coordination complexes or organic compounds containing enzymes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/06—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/096—Polyesters; Polyamides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
CH1053575A 1974-08-13 1975-08-13 CH624431A5 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3555674 1974-08-13
GB1743475A GB1463513A (en) 1974-08-13 1975-04-26 Enzymes

Publications (1)

Publication Number Publication Date
CH624431A5 true CH624431A5 (fr) 1981-07-31

Family

ID=26252681

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1053575A CH624431A5 (fr) 1974-08-13 1975-08-13

Country Status (19)

Country Link
US (1) US4267273A (fr)
JP (1) JPS5151582A (fr)
AR (2) AR216891A1 (fr)
AT (1) AT363889B (fr)
AU (1) AU497573B2 (fr)
BR (1) BR7505186A (fr)
CA (1) CA1053595A (fr)
CH (1) CH624431A5 (fr)
DE (1) DE2535951A1 (fr)
DK (1) DK143349C (fr)
ES (1) ES440240A1 (fr)
FI (1) FI752275A (fr)
FR (1) FR2288748A1 (fr)
GB (1) GB1463513A (fr)
IE (1) IE41894B1 (fr)
IL (1) IL47893A (fr)
MX (1) MX2951E (fr)
NL (1) NL7509667A (fr)
SE (2) SE7509008L (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5548392A (en) * 1978-02-17 1980-04-07 Toyo Jozo Co Ltd Novel immobilizing material combined with biologically active substance, its preparation, device comprising it, method, and preparation of support
SE416314B (sv) * 1978-04-03 1980-12-15 Svenska Sockerfabriks Ab Enzymatiskt forfarande, varvid enzymet foreligger i ett losligt komplex med hydrofob bindning och en del som modifierar enzymetsproduktivitetskinetiska egenskaper samt det losliga komplexet
DE2839737A1 (de) * 1978-09-13 1980-03-20 Roehm Gmbh Verfahren zur enzymatischen umsetzung mittels traegergebundener enzyme
DE2937964C2 (de) * 1979-09-20 1982-11-11 Peter 3400 Göttingen Schilling Mittel zur Bekämpfung der Karies
GB8334499D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Derivatives
US4632904A (en) * 1983-12-27 1986-12-30 Ciba Corning Diagnostics Corp. Immobilized enzyme composites having carriers derivatized with an organotitanate
US4795542A (en) * 1986-04-24 1989-01-03 St. Jude Medical, Inc. Electrochemical concentration detector device
EP0257758B1 (fr) * 1986-08-07 1993-03-10 Minnesota Mining And Manufacturing Company Emulsions fluorochimiques biologiquement actives, stables
US4808530A (en) * 1986-09-05 1989-02-28 The Ohio State University Protein immobilization by adsorption of a hydrophobic amidine protein derivative to a hydrophobic surface
US4885250A (en) * 1987-03-02 1989-12-05 E. I. Du Pont De Nemours And Company Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports
EP0353953A3 (fr) * 1988-08-04 1990-11-22 Imperial Chemical Industries Plc Procédé pour réaliser une réaction catalysée enzymatiquement
US5289855A (en) * 1988-10-14 1994-03-01 Elkay Manufacturing Co. Liquid container support and probe-type hygienic liquid dispensing system
US5295519A (en) * 1988-10-14 1994-03-22 Elkay Manufacturing Company Hygienic liquid dispensing system including feed tube or probe for opening and resealing coaxial cap
WO1990006996A1 (fr) * 1988-12-19 1990-06-28 Sepracor, Inc. Procede et appareil de confinement de catalyseurs dans des systemes de reactions multi-phase par membranes
US5270193A (en) * 1989-10-27 1993-12-14 E. I. Dupont De Nemours And Company Immobilization of biomolecules on perfluorocarbon surfaces
ES2036149A6 (es) * 1989-12-12 1993-05-01 Consejo Superior Investigacion Procedimiento de sintesis de antibioticos semiestaticos en sistemas termodinamicamente controlados agua-cosolventes organicos miscibles apolares con el empleo de penicilina g acilasa.
US5288619A (en) * 1989-12-18 1994-02-22 Kraft General Foods, Inc. Enzymatic method for preparing transesterified oils
AU644199B2 (en) * 1990-08-10 1993-12-02 Holmwood Highgate (Aust) Pty Ltd Road tanker
US5182201A (en) * 1990-10-26 1993-01-26 Uop Lipase immobilization without covalent bonding on an amphiphilic support containing lipophilic alkyl chains
FI20105572A0 (fi) 2010-05-24 2010-05-24 Prevab R Lcc Muokattu beeta-laktamaasi ja siihen liittyvät menetelmät ja käytöt
KR102360582B1 (ko) 2014-04-17 2022-02-08 신세틱 바이오로직스, 인코퍼레이티드 치료법을 위한 개선된 특성을 지니는 베타-락타마제
AU2015308897B2 (en) 2014-08-28 2021-03-04 Theriva Biologics, Inc. E. coli-based production of beta-lactamase
MX2017004473A (es) 2014-10-08 2017-10-12 Synthetic Biologics Inc Formulaciones de betalactamasa y usos de las mismas.
WO2016105498A1 (fr) 2014-12-23 2016-06-30 Synthetic Biologics, Inc. Méthodes et compositions pour inhiber ou prévenir les effets néfastes des antibiotiques oraux
AU2016222936B2 (en) 2015-02-23 2022-01-06 Theriva Biologics, Inc. Carbapenemases for use with antibiotics for the protection of the intestinal microbiome
KR20170122776A (ko) 2015-03-06 2017-11-06 신세틱 바이오로직스, 인코퍼레이티드 마이크로바이옴 보호를 위한 안전하고 유효한 베타-락타마제 투약
EP3875594A4 (fr) * 2018-10-30 2022-05-18 Wuhan Wuyao Pharmaceutical Co., Ltd. Procédé de préparation d'acide (r)-o-chloro-mandélique et système de réaction catalytique bioenzymatique cyclique pour le procédé de préparation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3706633A (en) * 1970-04-10 1972-12-19 Monsanto Co Preparation of water-insoluble enzyme derivatives
US3741871A (en) * 1972-01-04 1973-06-26 Monsanto Co Preparation of immobilized enzymes
GB1449808A (en) * 1972-11-21 1976-09-15 Beecham Group Ltd 6-aminopenicillanic acid preparation

Also Published As

Publication number Publication date
AT363889B (de) 1981-09-10
GB1463513A (en) 1977-02-02
SE8006247L (sv) 1980-09-08
AU497573B2 (en) 1978-12-21
AR218089A1 (es) 1980-05-15
AR216891A1 (es) 1980-02-15
ATA629375A (de) 1981-02-15
FI752275A (fr) 1976-02-14
IL47893A (en) 1978-07-31
DE2535951A1 (de) 1976-02-26
FR2288748B1 (fr) 1979-05-25
JPS5151582A (fr) 1976-05-07
IL47893A0 (en) 1975-11-25
NL7509667A (nl) 1976-02-17
IE41894B1 (en) 1980-04-23
DK143349C (da) 1981-12-07
IE41894L (en) 1976-02-13
US4267273A (en) 1981-05-12
SE7509008L (sv) 1976-02-16
ES440240A1 (es) 1978-06-01
DK143349B (da) 1981-08-10
AU8394275A (en) 1977-02-17
FR2288748A1 (fr) 1976-05-21
MX2951E (es) 1980-01-03
DK365275A (da) 1976-02-14
BR7505186A (pt) 1976-08-03
CA1053595A (fr) 1979-05-01

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PL Patent ceased