CH622528A5 - Process for the preparation of aminoglycoside antibiotics - Google Patents

Process for the preparation of aminoglycoside antibiotics Download PDF

Info

Publication number
CH622528A5
CH622528A5 CH457377A CH457377A CH622528A5 CH 622528 A5 CH622528 A5 CH 622528A5 CH 457377 A CH457377 A CH 457377A CH 457377 A CH457377 A CH 457377A CH 622528 A5 CH622528 A5 CH 622528A5
Authority
CH
Switzerland
Prior art keywords
group
amino
groups
formula
kanamycin
Prior art date
Application number
CH457377A
Other languages
English (en)
French (fr)
Inventor
William Alexander Million
Rhona Margaret Plews
Kenneth Richardson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CH622528A5 publication Critical patent/CH622528A5/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH457377A 1976-04-14 1977-04-13 Process for the preparation of aminoglycoside antibiotics CH622528A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB15421/76A GB1530201A (en) 1976-04-14 1976-04-14 Process for the preparation of aminoglycoside antibiotics and intermediates therefor

Publications (1)

Publication Number Publication Date
CH622528A5 true CH622528A5 (en) 1981-04-15

Family

ID=10058845

Family Applications (1)

Application Number Title Priority Date Filing Date
CH457377A CH622528A5 (en) 1976-04-14 1977-04-13 Process for the preparation of aminoglycoside antibiotics

Country Status (28)

Country Link
JP (2) JPS52139044A (ko)
AR (1) AR219074A1 (ko)
AT (1) AT356267B (ko)
AU (1) AU497416B2 (ko)
BE (1) BE853564A (ko)
BG (2) BG28072A4 (ko)
CA (1) CA1083568A (ko)
CH (1) CH622528A5 (ko)
CS (1) CS202570B2 (ko)
DD (2) DD135496A5 (ko)
DE (1) DE2716533C3 (ko)
DK (1) DK164277A (ko)
EG (1) EG12909A (ko)
ES (1) ES457793A1 (ko)
FI (1) FI771144A (ko)
FR (1) FR2348223A1 (ko)
GB (1) GB1530201A (ko)
GR (1) GR68936B (ko)
IE (1) IE45030B1 (ko)
IL (1) IL51775A (ko)
LU (1) LU77108A1 (ko)
NL (1) NL7703567A (ko)
NZ (1) NZ183733A (ko)
PH (1) PH14029A (ko)
PL (2) PL197372A1 (ko)
PT (1) PT66422B (ko)
RO (2) RO74431A (ko)
ZA (1) ZA771944B (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2924659A1 (de) * 1979-06-19 1981-01-22 Bayer Ag Pseudotrisaccharide, ihre herstellung und verwendung als arzneimittel
JPH0414628Y2 (ko) * 1984-12-13 1992-04-02
JPS61191642U (ko) * 1985-05-20 1986-11-28
IT1225484B (it) * 1987-11-27 1990-11-14 Pierrel Spa Procedimento di sintesi dell'amikacina
CN101481397B (zh) * 2009-01-23 2012-10-31 北京大学 一种新的卡那霉素a衍生物及其制备方法和用途
AU2011326871B2 (en) 2010-11-08 2015-02-12 Albireo Ab IBAT inhibitors for the treatment of liver diseases
JP6751020B2 (ja) 2014-06-25 2020-09-02 Eaファーマ株式会社 固形製剤及びその着色防止又は着色低減方法
JP6581082B2 (ja) 2014-06-25 2019-09-25 Eaファーマ株式会社 固形製剤及びその安定化方法
EP3012252A1 (en) 2014-10-24 2016-04-27 Ferring BV Crystal modifications of elobixibat
US10441604B2 (en) 2016-02-09 2019-10-15 Albireo Ab Cholestyramine pellets and methods for preparation thereof
US10441605B2 (en) 2016-02-09 2019-10-15 Albireo Ab Oral cholestyramine formulation and use thereof
US10786529B2 (en) 2016-02-09 2020-09-29 Albireo Ab Oral cholestyramine formulation and use thereof
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof

Also Published As

Publication number Publication date
DD130661A5 (de) 1978-04-19
BG28072A4 (en) 1980-02-25
BE853564A (fr) 1977-10-13
JPS52139044A (en) 1977-11-19
JPS5549587B2 (ko) 1980-12-12
RO74431A (ro) 1981-08-30
IL51775A (en) 1980-07-31
LU77108A1 (ko) 1979-01-18
PT66422B (en) 1978-09-18
ZA771944B (en) 1978-03-29
FI771144A (ko) 1977-10-15
DE2716533B2 (de) 1981-04-30
CS202570B2 (en) 1981-01-30
IE45030L (en) 1977-10-14
JPS535141A (en) 1978-01-18
PH14029A (en) 1980-12-12
BG27759A3 (en) 1979-12-12
IE45030B1 (en) 1982-06-02
DD135496A5 (de) 1979-05-09
JPS5421326B2 (ko) 1979-07-30
NL7703567A (nl) 1977-10-18
EG12909A (en) 1979-12-31
AT356267B (de) 1980-04-25
PL197372A1 (pl) 1979-06-18
GR68936B (ko) 1982-03-29
CA1083568A (en) 1980-08-12
ES457793A1 (es) 1978-08-01
DK164277A (da) 1977-10-15
FR2348223A1 (fr) 1977-11-10
DE2716533C3 (de) 1982-05-13
IL51775A0 (en) 1977-05-31
AR219074A1 (es) 1980-07-31
RO79969A (ro) 1983-02-01
PT66422A (en) 1977-05-01
DE2716533A1 (de) 1977-11-03
AU2372177A (en) 1978-10-05
RO79969B (ro) 1983-01-30
ATA261477A (de) 1979-09-15
GB1530201A (en) 1978-10-25
AU497416B2 (en) 1978-12-14
NZ183733A (en) 1979-12-11
PL112867B1 (en) 1980-11-29

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