CH616913A5 - - Google Patents

Download PDF

Info

Publication number
CH616913A5
CH616913A5 CH1338275A CH1338275A CH616913A5 CH 616913 A5 CH616913 A5 CH 616913A5 CH 1338275 A CH1338275 A CH 1338275A CH 1338275 A CH1338275 A CH 1338275A CH 616913 A5 CH616913 A5 CH 616913A5
Authority
CH
Switzerland
Prior art keywords
histidyl
acid
group
water
formula
Prior art date
Application number
CH1338275A
Other languages
German (de)
English (en)
Inventor
Eberhard Dr Schwertner
Siegfried Dr Herrlind
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2449167A external-priority patent/DE2449167C2/de
Priority claimed from DE19752527723 external-priority patent/DE2527723A1/de
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of CH616913A5 publication Critical patent/CH616913A5/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH1338275A 1974-10-16 1975-10-15 CH616913A5 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2449167A DE2449167C2 (de) 1974-10-16 1974-10-16 N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
DE19752527723 DE2527723A1 (de) 1975-06-21 1975-06-21 Verfahren zur herstellung von dipeptid-derivaten

Publications (1)

Publication Number Publication Date
CH616913A5 true CH616913A5 (ru) 1980-04-30

Family

ID=25767820

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1338275A CH616913A5 (ru) 1974-10-16 1975-10-15

Country Status (12)

Country Link
US (1) US4045556A (ru)
JP (1) JPS609518B2 (ru)
CA (1) CA1056818A (ru)
CH (1) CH616913A5 (ru)
DK (1) DK149063C (ru)
ES (1) ES441788A1 (ru)
FR (1) FR2287916A1 (ru)
GB (1) GB1519636A (ru)
IE (1) IE41803B1 (ru)
NL (1) NL183764C (ru)
SE (1) SE408300B (ru)
YU (1) YU39330B (ru)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4125578A (en) * 1977-11-09 1979-05-17 Merck & Co Inc Tripeptides
US4182856A (en) * 1978-04-25 1980-01-08 Miles Laboratories, Inc. Reagents for use in binding assays to determine diphenylhydantoin
HU180926B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem
GB2146026A (en) * 1983-09-07 1985-04-11 Tanabe Seiyaku Co Peptides and process for preparing the same
US4608365A (en) * 1984-03-30 1986-08-26 University Of Southern California Treatment of neurologic functions
IL75641A (en) * 1984-07-10 1990-11-05 Tanabe Seiyaku Co 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it
IE58849B1 (en) * 1984-12-18 1993-11-17 Gruenenthal Chemie Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis
GB2171101A (en) * 1985-02-20 1986-08-20 Tanabe Seiyaku Co Peptide and processes for preparation of the same
US5151497A (en) * 1989-02-21 1992-09-29 Japan Tobacco Inc. Histidyl peptide derivatives
AU5365494A (en) * 1992-10-22 1994-05-09 Peter G. Thomas New method of protecting central nervous system against damage resulting from cerebrovascular or neuronal compromise
BE1007183A3 (fr) * 1993-06-18 1995-04-18 Solvay Ureines derivees d'alpha, omega-diaminoacides et procede pour leur preparation.
DK0866711T3 (da) * 1995-10-24 2006-11-27 Gruenenthal Gmbh Anvendelse af 6-methyl-5-oxo-3-thiomorpholinylcarbonyl-L-histidyl-L-prolinamid til fremstilling af et farmaceutisk præparat til modvirkning af sövnapnö
US5932541A (en) * 1995-10-24 1999-08-03 Gruenenthal Gmbh Method of adjusting the circadian rhythm of a mammal
DE10025949A1 (de) * 2000-05-26 2001-11-29 Gruenenthal Gmbh Arzneimittel zur Bekämpfung von Atemdepression
JP4817281B2 (ja) 2000-08-31 2011-11-16 塩野義製薬株式会社 パーキンソン病治療剤
KR101137503B1 (ko) * 2009-07-14 2012-04-20 웰이앤씨 주식회사 고분자 고체 지지체를 이용한 히스티딜-프롤린아미드 유도체의 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5714337B2 (ru) * 1973-02-23 1982-03-24

Also Published As

Publication number Publication date
US4045556A (en) 1977-08-30
CA1056818A (en) 1979-06-19
SE408300B (sv) 1979-06-05
NL183764B (nl) 1988-08-16
IE41803B1 (en) 1980-03-26
YU39330B (en) 1984-10-31
IE41803L (en) 1976-04-16
DK463775A (da) 1976-04-17
DK149063B (da) 1986-01-06
YU232475A (en) 1982-02-28
JPS5165775A (ru) 1976-06-07
GB1519636A (en) 1978-08-02
ES441788A1 (es) 1977-06-16
FR2287916B1 (ru) 1978-07-28
SE7509703L (ru) 1976-04-17
JPS609518B2 (ja) 1985-03-11
FR2287916A1 (fr) 1976-05-14
DK149063C (da) 1986-06-16
NL183764C (nl) 1989-01-16
NL7510288A (nl) 1976-04-21

Similar Documents

Publication Publication Date Title
CH616913A5 (ru)
EP0111873B1 (de) Derivate der cis, endo-2-Azabicyclo-(5.3.0)-decan-3-carbonsäure, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung
EP0142739B1 (de) Aminosäurederivate und Verfahren zu ihrer Herstellung
CH634548A5 (de) Verfahren zur herstellung von neuen peptiden.
CH620196A5 (ru)
CH650519A5 (de) Auf das zentrale nervensystem wirkende tripeptide und verfahren zur herstellung derselben.
DE2449167A1 (de) Dipeptidderivate
DE2840636C2 (ru)
DE2609154C2 (de) L-Pyroglutamyl-L-histidyl-prolinamide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
CH664956A5 (de) Proline.
DE2343035A1 (de) Tripeptide mit antidepressiver und prolactinausschuettender wirkung und verfahren zu ihrer herstellung
DE2615455A1 (de) Dipeptidderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungsformen
DE2063996A1 (de) Neue Tuberkulostatisch wirkende alpha Aminoxy hydroxamsaurederivate und Verfahren zur Herstellung derselben
DE1961947A1 (de) 6,7-Diacyloxy-tetrahydroisochinolinverbindungen und Verfahren zu ihrer Herstellung
AT354657B (de) Verfahren zur herstellung von neuen dipeptid- -derivaten
DE69738349T2 (de) Anthranilsäurediamid-derivate, ihre herstellung und pharmazeutische verwendung als antigastrinmittel
DE2754770C2 (de) N-Acyltetrapeptidamide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE1958383C3 (de) Leupeptine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2725732C2 (de) Bestatin-Analoga, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
AT354658B (de) Verfahren zur herstellung von neuen dipeptid- -derivaten
AT360186B (de) Verfahren zur herstellung von neuen dipeptid- -derivaten
DE1295565B (de) Verfahren zur Herstellung von einen Histidinrest enthaltenden Peptiden
EP0716658B1 (de) Glycosylamide von 2-aminoacylamino-2-desoxy-zuckern
DE2022623A1 (de) Peptidverbindungen mit Tyrosin-O-sulfatresten
DE2727048C2 (de) 8-Norleucyl-ceruletide

Legal Events

Date Code Title Description
PFA Name/firm changed

Owner name: GRUENENTHAL GMBH

PFA Name/firm changed

Owner name: GRUENENTHAL GMBH

PL Patent ceased