ES441788A1 - Procedimiento para la obtencion de derivadas de depeptidos. - Google Patents
Procedimiento para la obtencion de derivadas de depeptidos.Info
- Publication number
- ES441788A1 ES441788A1 ES441788A ES441788A ES441788A1 ES 441788 A1 ES441788 A1 ES 441788A1 ES 441788 A ES441788 A ES 441788A ES 441788 A ES441788 A ES 441788A ES 441788 A1 ES441788 A1 ES 441788A1
- Authority
- ES
- Spain
- Prior art keywords
- histidyl
- prolinamide
- manufacture
- pharmaceutical preparations
- dipeptide derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010016626 Dipeptides Proteins 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- LNCFUHAPNTYMJB-IUCAKERBSA-N His-Pro Chemical compound C([C@H](N)C(=O)N1[C@@H](CCC1)C(O)=O)C1=CN=CN1 LNCFUHAPNTYMJB-IUCAKERBSA-N 0.000 abstract 1
- VLJNHYLEOZPXFW-BYPYZUCNSA-N L-prolinamide Chemical compound NC(=O)[C@@H]1CCCN1 VLJNHYLEOZPXFW-BYPYZUCNSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 108010085325 histidylproline Proteins 0.000 abstract 1
- 239000003368 psychostimulant agent Substances 0.000 abstract 1
- 230000002582 psychostimulating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2449167A DE2449167C2 (de) | 1974-10-16 | 1974-10-16 | N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
| DE19752527723 DE2527723A1 (de) | 1975-06-21 | 1975-06-21 | Verfahren zur herstellung von dipeptid-derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES441788A1 true ES441788A1 (es) | 1977-06-16 |
Family
ID=25767820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES441788A Expired ES441788A1 (es) | 1974-10-16 | 1975-10-14 | Procedimiento para la obtencion de derivadas de depeptidos. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4045556A (es) |
| JP (1) | JPS609518B2 (es) |
| CA (1) | CA1056818A (es) |
| CH (1) | CH616913A5 (es) |
| DK (1) | DK149063C (es) |
| ES (1) | ES441788A1 (es) |
| FR (1) | FR2287916A1 (es) |
| GB (1) | GB1519636A (es) |
| IE (1) | IE41803B1 (es) |
| NL (1) | NL183764C (es) |
| SE (1) | SE408300B (es) |
| YU (1) | YU39330B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4125578A (en) * | 1977-11-09 | 1979-05-17 | Merck & Co Inc | Tripeptides |
| US4182856A (en) * | 1978-04-25 | 1980-01-08 | Miles Laboratories, Inc. | Reagents for use in binding assays to determine diphenylhydantoin |
| HU180926B (en) * | 1979-06-28 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem |
| GB2146026A (en) * | 1983-09-07 | 1985-04-11 | Tanabe Seiyaku Co | Peptides and process for preparing the same |
| US4608365A (en) * | 1984-03-30 | 1986-08-26 | University Of Southern California | Treatment of neurologic functions |
| IL75641A (en) * | 1984-07-10 | 1990-11-05 | Tanabe Seiyaku Co | 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it |
| IE58849B1 (en) * | 1984-12-18 | 1993-11-17 | Gruenenthal Chemie | Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis |
| GB2171101A (en) * | 1985-02-20 | 1986-08-20 | Tanabe Seiyaku Co | Peptide and processes for preparation of the same |
| US5151497A (en) * | 1989-02-21 | 1992-09-29 | Japan Tobacco Inc. | Histidyl peptide derivatives |
| AU5365494A (en) * | 1992-10-22 | 1994-05-09 | Peter G. Thomas | New method of protecting central nervous system against damage resulting from cerebrovascular or neuronal compromise |
| BE1007183A3 (fr) * | 1993-06-18 | 1995-04-18 | Solvay | Ureines derivees d'alpha, omega-diaminoacides et procede pour leur preparation. |
| DE69636393T2 (de) * | 1995-10-24 | 2006-12-07 | Grünenthal GmbH | Montirelin zur verhinderung der schlafapnoe |
| JPH11515014A (ja) * | 1995-10-24 | 1999-12-21 | グルーエネンタール ゲゼルシャフト ミット ベシュレンクテル ハフツング | 哺乳類の概日リズムの調整方法 |
| DE10025949A1 (de) * | 2000-05-26 | 2001-11-29 | Gruenenthal Gmbh | Arzneimittel zur Bekämpfung von Atemdepression |
| KR20050105290A (ko) | 2000-08-31 | 2005-11-03 | 시오노기세이야쿠가부시키가이샤 | 파킨슨씨병 치료제 |
| KR101137503B1 (ko) * | 2009-07-14 | 2012-04-20 | 웰이앤씨 주식회사 | 고분자 고체 지지체를 이용한 히스티딜-프롤린아미드 유도체의 제조 방법 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5714337B2 (es) * | 1973-02-23 | 1982-03-24 |
-
1975
- 1975-09-01 NL NLAANVRAGE7510288,A patent/NL183764C/xx not_active IP Right Cessation
- 1975-09-01 SE SE7509703A patent/SE408300B/xx not_active IP Right Cessation
- 1975-09-15 YU YU2324/75A patent/YU39330B/xx unknown
- 1975-10-01 IE IE2145/75A patent/IE41803B1/en unknown
- 1975-10-01 GB GB40123/75A patent/GB1519636A/en not_active Expired
- 1975-10-14 ES ES441788A patent/ES441788A1/es not_active Expired
- 1975-10-14 JP JP50122966A patent/JPS609518B2/ja not_active Expired
- 1975-10-15 DK DK463775A patent/DK149063C/da not_active IP Right Cessation
- 1975-10-15 CA CA237,665A patent/CA1056818A/en not_active Expired
- 1975-10-15 FR FR7531599A patent/FR2287916A1/fr active Granted
- 1975-10-15 CH CH1338275A patent/CH616913A5/de not_active IP Right Cessation
- 1975-10-16 US US05/622,804 patent/US4045556A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| YU39330B (en) | 1984-10-31 |
| GB1519636A (en) | 1978-08-02 |
| NL183764C (nl) | 1989-01-16 |
| YU232475A (en) | 1982-02-28 |
| CH616913A5 (es) | 1980-04-30 |
| SE7509703L (es) | 1976-04-20 |
| FR2287916B1 (es) | 1978-07-28 |
| DK149063B (da) | 1986-01-06 |
| SE408300B (sv) | 1979-06-05 |
| NL7510288A (nl) | 1976-04-21 |
| JPS5165775A (es) | 1976-06-07 |
| IE41803B1 (en) | 1980-03-26 |
| FR2287916A1 (fr) | 1976-05-14 |
| DK463775A (da) | 1976-04-17 |
| JPS609518B2 (ja) | 1985-03-11 |
| IE41803L (en) | 1976-04-16 |
| US4045556A (en) | 1977-08-30 |
| DK149063C (da) | 1986-06-16 |
| CA1056818A (en) | 1979-06-19 |
| NL183764B (nl) | 1988-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19920224 |