CH613709A5 - Process for the preparation of glucosamine derivatives - Google Patents

Process for the preparation of glucosamine derivatives

Info

Publication number
CH613709A5
CH613709A5 CH1604275A CH1604275A CH613709A5 CH 613709 A5 CH613709 A5 CH 613709A5 CH 1604275 A CH1604275 A CH 1604275A CH 1604275 A CH1604275 A CH 1604275A CH 613709 A5 CH613709 A5 CH 613709A5
Authority
CH
Switzerland
Prior art keywords
preparation
glucosamine derivatives
glucosamine
derivatives
Prior art date
Application number
CH1604275A
Other languages
English (en)
Inventor
Gerhard Baschang
Jaroslav Stanek
Alex Sele
Albert Hartmann
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH1604275A priority Critical patent/CH613709A5/xx
Priority to GB51228/76A priority patent/GB1570625A/en
Priority to SU762428152A priority patent/SU660589A3/ru
Priority to NL7613666A priority patent/NL7613666A/xx
Priority to GR52361A priority patent/GR61647B/el
Priority to CA000267474A priority patent/CA1262400A/en
Priority to DE19762655500 priority patent/DE2655500A1/de
Priority to SE7613851A priority patent/SE445923B/xx
Priority to CS768063A priority patent/CS205026B2/cs
Priority to IE2689/76A priority patent/IE44190B1/en
Priority to CS768063A priority patent/CS205025B2/cs
Priority to DK552476A priority patent/DK154654C/da
Priority to AT0909276A priority patent/AT365607B/de
Priority to DD7600196215A priority patent/DD129781A5/xx
Priority to AU20422/76A priority patent/AU508764B2/en
Priority to NO764191A priority patent/NO144850C/no
Priority to CS768063A priority patent/CS205027B2/cs
Priority to CS768063A priority patent/CS205028B2/cs
Priority to NZ182837A priority patent/NZ182837A/xx
Priority to FI763541A priority patent/FI64164C/fi
Priority to FR7637091A priority patent/FR2361902A1/fr
Priority to PT65946A priority patent/PT65946B/pt
Priority to HU76CI1702A priority patent/HU177970B/hu
Priority to BE173091A priority patent/BE849214A/xx
Priority to ZA767333A priority patent/ZA767333B/xx
Priority to IL51076A priority patent/IL51076A/xx
Priority to PL1976210826A priority patent/PL112672B1/pl
Priority to PL1976194291A priority patent/PL110353B1/pl
Priority to JP51147903A priority patent/JPS5273820A/ja
Priority to ES454118A priority patent/ES454118A1/es
Priority to PL1976210827A priority patent/PL110787B1/pl
Priority to PL1976210828A priority patent/PL110794B1/pl
Priority to AR265799A priority patent/AR224091A1/es
Priority to SU772521659A priority patent/SU747430A3/ru
Priority to SU772518658A priority patent/SU1060118A3/ru
Priority to AR269405A priority patent/AR220686A1/es
Priority to ES465514A priority patent/ES465514A1/es
Priority to CH898378A priority patent/CH614718A5/xx
Priority to AT537079A priority patent/AT360557B/de
Priority to AT536979A priority patent/AT359089B/de
Publication of CH613709A5 publication Critical patent/CH613709A5/xx
Priority to AT143381A priority patent/AT372091B/de
Priority to SG110/83A priority patent/SG11083G/en
Priority to HK328/83A priority patent/HK32883A/xx
Priority to MY123/84A priority patent/MY8400123A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1604275A 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives CH613709A5 (en)

Priority Applications (44)

Application Number Priority Date Filing Date Title
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives
GB51228/76A GB1570625A (en) 1975-12-10 1976-12-08 Glucosamine derivatives and a process for their manufacture
SU762428152A SU660589A3 (ru) 1975-12-10 1976-12-08 Способ получени производных глюкозамина или их солей
NL7613666A NL7613666A (nl) 1975-12-10 1976-12-08 Glucosaminederivaten.
GR52361A GR61647B (en) 1975-12-10 1976-12-08 Preparation process of glucosam in derivatives
CA000267474A CA1262400A (en) 1975-12-10 1976-12-08 Process for the manufacture of glucosamine derivatives
DE19762655500 DE2655500A1 (de) 1975-12-10 1976-12-08 Glucosaminderivate und ein verfahren zu deren herstellung
PT65946A PT65946B (en) 1975-12-10 1976-12-09 Process for the manufacture of glucosamine derivatives
CS768063A CS205026B2 (en) 1975-12-10 1976-12-09 Method of producing glocosamine derivatives
IE2689/76A IE44190B1 (en) 1975-12-10 1976-12-09 Glucosamine derivatives and a process for their manufacture
CS768063A CS205025B2 (en) 1975-12-10 1976-12-09 Process for preparing derivatives of glukosamine
DK552476A DK154654C (da) 1975-12-10 1976-12-09 Analogifremgangsmaade til fremstilling af immunmodulerende 2-oe2-acylamino-2-desoxy-(d)-glucosyl-3-oaa-alkancarboxylsyrepeptid-derivater eller farmaceutisk acceptable salte deraf
AT0909276A AT365607B (de) 1975-12-10 1976-12-09 Verfahren zur herstellung von neuen glucosaminderivaten
DD7600196215A DD129781A5 (de) 1975-12-10 1976-12-09 Verfahren zur herstellung von glucoseaminderivaten
AU20422/76A AU508764B2 (en) 1975-12-10 1976-12-09 Glucosamine derivatives
NO764191A NO144850C (no) 1975-12-10 1976-12-09 Analogifremgangsmaate til fremstilling av immunpotenserende glukosaminderivater.
CS768063A CS205027B2 (en) 1975-12-10 1976-12-09 Method of producing glucosamine derivatives
CS768063A CS205028B2 (en) 1975-12-10 1976-12-09 Method of producing glucosamine derivatives
NZ182837A NZ182837A (en) 1975-12-10 1976-12-09 Glucosamine derivatives and pharmaceutical compositions
FI763541A FI64164C (fi) 1975-12-10 1976-12-09 Foerfarande foer framstaellning av 2-(2-acylamino-2-desoxi-(d)-glukosyl-3-0)-alkankarboxylsyrapeptid-derivat
FR7637091A FR2361902A1 (fr) 1975-12-10 1976-12-09 Derives de la glucosamine et leur procede de fabrication
SE7613851A SE445923B (sv) 1975-12-10 1976-12-09 Forfarande for framstellning av glukosaminderivat
HU76CI1702A HU177970B (en) 1975-12-10 1976-12-09 Process for producing new glucosamine derivatives
BE173091A BE849214A (fr) 1975-12-10 1976-12-09 Derives de la glucosine et leur procede de fabrication
ZA767333A ZA767333B (en) 1975-12-10 1976-12-09 Glucosamine derivatives and a process for their manufacture
IL51076A IL51076A (en) 1975-12-10 1976-12-09 Glucosamine-3-alkanoyl-dipeptides, their manufacture and ppharmaceutical compositions containing them
PL1976210826A PL112672B1 (en) 1975-12-10 1976-12-10 Process for preparing novel derivatives of glycosamine
PL1976194291A PL110353B1 (en) 1975-12-10 1976-12-10 Method of producing new derivatives of glucosoamine
JP51147903A JPS5273820A (en) 1975-12-10 1976-12-10 Glucosamine derivative and its method of manufacturing
ES454118A ES454118A1 (es) 1975-12-10 1976-12-10 Procedimiento para la obtencion de derivados de flucosamina.
PL1976210827A PL110787B1 (en) 1975-12-10 1976-12-10 Method of producing new derivatives of glucosoamine
PL1976210828A PL110794B1 (en) 1975-12-10 1976-12-10 Method of producing new derivatives of glucosoamine
AR265799A AR224091A1 (es) 1975-12-10 1976-12-10 Procedimiento para obtener derivados de 3-o-carbamoil-alquil(c1-c3)-2-deoxi-2-amino-glucopiranosidos
SU772521659A SU747430A3 (ru) 1975-12-10 1977-09-08 Способ получени глюкозамина или его солей
SU772518658A SU1060118A3 (ru) 1975-12-10 1977-09-08 Способ получени производных глюкозамина
AR269405A AR220686A1 (es) 1975-12-10 1977-09-30 Procedimiento para obtener derivados de 2 amino-2-desoxi-3-o-(propilcarbamoilmetil)-carbamoilmetil-glucopiranosa y sus sales
ES465514A ES465514A1 (es) 1975-12-10 1977-12-28 Procedimiento para la obtencion de derivados de glucosamina.
CH898378A CH614718A5 (en) 1975-12-10 1978-08-24 Process for the preparation of glucosamine derivatives
AT537079A AT360557B (de) 1975-12-10 1979-08-06 Verfahren zur herstellung von neuen glucosaminderivaten
AT536979A AT359089B (de) 1975-12-10 1979-08-06 Verfahren zur herstellung von neuen glucosaminderivaten
AT143381A AT372091B (de) 1975-12-10 1981-03-27 Verfahren zur herstellung von glucosaminderivaten
SG110/83A SG11083G (en) 1975-12-10 1983-03-14 Glucosamine derivatives and a process for their manufacture
HK328/83A HK32883A (en) 1975-12-10 1983-08-25 Glucosamine derivatives and a process for their manufacture
MY123/84A MY8400123A (en) 1975-12-10 1984-12-30 Glucosamine derivatives and a process for their manufacture

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives

Publications (1)

Publication Number Publication Date
CH613709A5 true CH613709A5 (en) 1979-10-15

Family

ID=4414012

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives
CH898378A CH614718A5 (en) 1975-12-10 1978-08-24 Process for the preparation of glucosamine derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH898378A CH614718A5 (en) 1975-12-10 1978-08-24 Process for the preparation of glucosamine derivatives

Country Status (30)

Country Link
JP (1) JPS5273820A (da)
AR (2) AR224091A1 (da)
AT (1) AT365607B (da)
AU (1) AU508764B2 (da)
BE (1) BE849214A (da)
CA (1) CA1262400A (da)
CH (2) CH613709A5 (da)
CS (4) CS205028B2 (da)
DD (1) DD129781A5 (da)
DE (1) DE2655500A1 (da)
DK (1) DK154654C (da)
ES (2) ES454118A1 (da)
FI (1) FI64164C (da)
FR (1) FR2361902A1 (da)
GB (1) GB1570625A (da)
GR (1) GR61647B (da)
HK (1) HK32883A (da)
HU (1) HU177970B (da)
IE (1) IE44190B1 (da)
IL (1) IL51076A (da)
MY (1) MY8400123A (da)
NL (1) NL7613666A (da)
NO (1) NO144850C (da)
NZ (1) NZ182837A (da)
PL (4) PL112672B1 (da)
PT (1) PT65946B (da)
SE (1) SE445923B (da)
SG (1) SG11083G (da)
SU (3) SU660589A3 (da)
ZA (1) ZA767333B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2718010A1 (de) * 1976-04-26 1977-11-10 Syntex Inc Neue immunologische adjuvansverbindungen und verfahren zur herstellung derselben

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
DE2862107D1 (en) 1977-12-02 1982-11-18 Takeda Chemical Industries Ltd Glucosamine-peptide derivatives and their pharmaceutical compositions
CA1138436A (en) * 1978-02-24 1982-12-28 Gerhard Baschang Process for the manufacture of novel antigens
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
FR2420545A1 (fr) * 1978-03-20 1979-10-19 Anvar Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
FR2428051A1 (fr) * 1978-06-05 1980-01-04 Anvar Nouveaux composes du type muramyl-peptide et medicaments les contenant
FR2428050A1 (fr) * 1978-06-05 1980-01-04 Anvar Oligomeres de composes du type muramyl-peptide et medicaments les contenant
FR2446292A1 (fr) * 1979-01-12 1980-08-08 Anvar Muramyl-peptides fixes sur polymeres peptidiques et medicaments les contenant
US4256735A (en) 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
FR2449697A1 (fr) 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
FI75578C (fi) 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
JPS5649396A (en) * 1979-09-28 1981-05-02 Dai Ichi Seiyaku Co Ltd Novel muramyldipeptide derivative
DE3070457D1 (en) * 1979-10-02 1985-05-15 Ciba Geigy Ag Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production
FI803077A (fi) 1979-10-12 1981-04-13 Ciba Geigy Ag Foerfarande foer framstaellning av myramylpeptider
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4310514A (en) 1980-05-05 1982-01-12 Merck & Co., Inc. Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP0056560A1 (de) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Antibiotische Präparate mit gesteigerter Wirksamkeit, Verfahren zu deren Herstellung und Verfahren zur Steigerung der antibiotischen Wirkung von Antibiotika
GR78246B (da) * 1981-01-23 1984-09-26 Ciba Geigy Ag
JPS6042398A (ja) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka ムラミルジペプチド活性エステル誘導体
EP0541486A1 (de) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclische Konjugate
US7838685B2 (en) 2005-04-27 2010-11-23 Shinji Takeoka Cationic amino acid type lipid
US10610564B2 (en) 2015-02-26 2020-04-07 Stc.Unm IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
WO2017098529A1 (en) 2015-12-10 2017-06-15 Bharat Biotech International Limited Novel muramyl peptide derivative compound, synthesis and uses thereof
US10576147B2 (en) * 2015-12-15 2020-03-03 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
CA3072735A1 (en) 2017-08-21 2019-02-28 Celgene Corporation Processes for the preparation of (s)-tert-butyl 4,5-diamino-5-oxopentanoate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2718010A1 (de) * 1976-04-26 1977-11-10 Syntex Inc Neue immunologische adjuvansverbindungen und verfahren zur herstellung derselben

Also Published As

Publication number Publication date
ZA767333B (en) 1977-11-30
IE44190L (en) 1977-06-10
DE2655500A1 (de) 1977-06-23
DK154654C (da) 1989-05-08
FI763541A (da) 1977-06-11
ES465514A1 (es) 1978-09-16
IL51076A0 (en) 1977-02-28
FR2361902A1 (fr) 1978-03-17
SE445923B (sv) 1986-07-28
PT65946B (en) 1978-06-14
DD129781A5 (de) 1978-02-08
NO144850C (no) 1981-11-25
NO764191L (da) 1977-06-13
CS205027B2 (en) 1981-04-30
CS205028B2 (en) 1981-04-30
SE7613851L (sv) 1977-06-11
FR2361902B1 (da) 1980-11-07
MY8400123A (en) 1984-12-31
JPS5273820A (en) 1977-06-21
AT365607B (de) 1982-02-10
ATA909276A (de) 1981-06-15
BE849214A (fr) 1977-06-09
AR220686A1 (es) 1980-11-28
IE44190B1 (en) 1981-09-09
NZ182837A (en) 1978-07-28
HK32883A (en) 1983-09-02
DK552476A (da) 1977-06-11
AU508764B2 (en) 1980-04-03
PT65946A (en) 1977-01-01
PL194291A1 (pl) 1978-10-23
DE2655500C2 (da) 1988-12-22
JPS638118B2 (da) 1988-02-19
SU660589A3 (ru) 1979-04-30
PL112672B1 (en) 1980-10-31
ES454118A1 (es) 1978-03-01
PL110787B1 (en) 1980-07-31
PL110353B1 (en) 1980-07-31
NO144850B (no) 1981-08-17
AU2042276A (en) 1978-06-15
IL51076A (en) 1980-09-16
CH614718A5 (en) 1979-12-14
AR224091A1 (es) 1981-10-30
CA1262400A (en) 1989-10-17
HU177970B (en) 1982-02-28
FI64164B (fi) 1983-06-30
SG11083G (en) 1983-09-16
PL110794B1 (en) 1980-07-31
CS205025B2 (en) 1981-04-30
CS205026B2 (en) 1981-04-30
NL7613666A (nl) 1977-06-14
FI64164C (fi) 1983-10-10
SU1060118A3 (ru) 1983-12-07
DK154654B (da) 1988-12-05
GB1570625A (en) 1980-07-02
GR61647B (en) 1978-12-05
SU747430A3 (ru) 1980-07-23

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