CH612431A5 - Process for the preparation of novel indole derivatives - Google Patents
Process for the preparation of novel indole derivativesInfo
- Publication number
- CH612431A5 CH612431A5 CH1155178A CH1155178A CH612431A5 CH 612431 A5 CH612431 A5 CH 612431A5 CH 1155178 A CH1155178 A CH 1155178A CH 1155178 A CH1155178 A CH 1155178A CH 612431 A5 CH612431 A5 CH 612431A5
- Authority
- CH
- Switzerland
- Prior art keywords
- compounds
- preparation
- indole derivatives
- hypotensive
- novel indole
- Prior art date
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000001077 hypotensive effect Effects 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- -1 isothiocyanato-indol compound Chemical class 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4720873 | 1973-10-10 | ||
| GB353174*[A GB1425354A (en) | 1973-10-10 | 1974-01-25 | Indole derivatives |
| GB727774 | 1974-02-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH612431A5 true CH612431A5 (en) | 1979-07-31 |
Family
ID=27254287
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1155178A CH612431A5 (en) | 1973-10-10 | 1974-10-09 | Process for the preparation of novel indole derivatives |
| CH1155278A CH611615A5 (en) | 1973-10-10 | 1974-10-09 | Process for the preparation of novel indole derivatives |
| CH1155378A CH613449A5 (en) | 1973-10-10 | 1974-10-09 | Process for the preparation of novel indole derivatives |
| CH1358574A CH610323A5 (en) | 1973-10-10 | 1974-10-09 | Process for the preparation of indole derivatives |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1155278A CH611615A5 (en) | 1973-10-10 | 1974-10-09 | Process for the preparation of novel indole derivatives |
| CH1155378A CH613449A5 (en) | 1973-10-10 | 1974-10-09 | Process for the preparation of novel indole derivatives |
| CH1358574A CH610323A5 (en) | 1973-10-10 | 1974-10-09 | Process for the preparation of indole derivatives |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS6039678B2 (enrdf_load_stackoverflow) |
| CH (4) | CH612431A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2447947A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2247239B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1425354A (enrdf_load_stackoverflow) |
| HK (1) | HK36179A (enrdf_load_stackoverflow) |
| IE (1) | IE40052B1 (enrdf_load_stackoverflow) |
| KE (1) | KE2950A (enrdf_load_stackoverflow) |
| MY (1) | MY7900210A (enrdf_load_stackoverflow) |
| NL (1) | NL179731C (enrdf_load_stackoverflow) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147786A (en) | 1976-02-02 | 1979-04-03 | Ciba-Geigy Corporation | 1-Indolylalkyl-3-or 4-trimethyleneurido-piperidines |
| GB1542137A (en) * | 1976-03-12 | 1979-03-14 | Wyeth John & Brother Ltd | Process for preparing 3(piperidinoalkyl)indoles |
| JPS56158Y2 (enrdf_load_stackoverflow) * | 1976-06-28 | 1981-01-06 | ||
| GB1586817A (en) * | 1977-12-01 | 1981-03-25 | Wyeth John & Brother Ltd | Indole derivatives |
| US4242347A (en) | 1979-06-18 | 1980-12-30 | Ciba-Geigy Corporation | Hypotensive indolylalkylpiperidyl guanidines and isoureas |
| JPS62157297U (enrdf_load_stackoverflow) * | 1986-03-27 | 1987-10-06 | ||
| DK733788A (da) * | 1988-01-14 | 1989-07-15 | Fujisawa Pharmaceutical Co | Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf |
| SE9902987D0 (sv) | 1999-08-24 | 1999-08-24 | Astra Pharma Prod | Novel compounds |
| FR2802206B1 (fr) * | 1999-12-14 | 2005-04-22 | Sod Conseils Rech Applic | Derives de 4-aminopiperidine et leur utilisation en tant que medicament |
| GB0011838D0 (en) * | 2000-05-17 | 2000-07-05 | Astrazeneca Ab | Chemical compounds |
| GB0104050D0 (en) | 2001-02-19 | 2001-04-04 | Astrazeneca Ab | Chemical compounds |
| GB0107228D0 (en) | 2001-03-22 | 2001-05-16 | Astrazeneca Ab | Chemical compounds |
| SE0103818D0 (sv) | 2001-11-15 | 2001-11-15 | Astrazeneca Ab | Chemical compounds |
| SE0301369D0 (sv) | 2003-05-09 | 2003-05-09 | Astrazeneca Ab | Chemical compounds |
-
1974
- 1974-01-25 GB GB353174*[A patent/GB1425354A/en not_active Expired
- 1974-09-23 IE IE1956/74A patent/IE40052B1/xx unknown
- 1974-10-08 DE DE19742447947 patent/DE2447947A1/de not_active Ceased
- 1974-10-09 CH CH1155178A patent/CH612431A5/xx not_active IP Right Cessation
- 1974-10-09 CH CH1155278A patent/CH611615A5/xx not_active IP Right Cessation
- 1974-10-09 CH CH1155378A patent/CH613449A5/xx not_active IP Right Cessation
- 1974-10-09 CH CH1358574A patent/CH610323A5/xx not_active IP Right Cessation
- 1974-10-09 FR FR7433967A patent/FR2247239B1/fr not_active Expired
- 1974-10-09 JP JP49115686A patent/JPS6039678B2/ja not_active Expired
- 1974-10-10 NL NLAANVRAGE7413358,A patent/NL179731C/xx not_active IP Right Cessation
-
1979
- 1979-04-10 KE KE2950A patent/KE2950A/xx unknown
- 1979-06-07 HK HK361/79A patent/HK36179A/xx unknown
- 1979-12-31 MY MY1979210A patent/MY7900210A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2447947A1 (de) | 1975-04-17 |
| MY7900210A (en) | 1979-12-31 |
| FR2247239A1 (enrdf_load_stackoverflow) | 1975-05-09 |
| CH613449A5 (en) | 1979-09-28 |
| CH611615A5 (en) | 1979-06-15 |
| KE2950A (en) | 1979-04-27 |
| HK36179A (en) | 1979-06-15 |
| NL7413358A (nl) | 1975-04-14 |
| GB1425354A (en) | 1976-02-18 |
| NL179731C (nl) | 1986-11-03 |
| JPS6039678B2 (ja) | 1985-09-06 |
| IE40052L (en) | 1975-04-10 |
| FR2247239B1 (enrdf_load_stackoverflow) | 1978-07-21 |
| JPS5076076A (enrdf_load_stackoverflow) | 1975-06-21 |
| NL179731B (nl) | 1986-06-02 |
| CH610323A5 (en) | 1979-04-12 |
| IE40052B1 (en) | 1979-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |