GB1425354A - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number
GB1425354A
GB1425354A GB353174*[A GB353174A GB1425354A GB 1425354 A GB1425354 A GB 1425354A GB 353174 A GB353174 A GB 353174A GB 1425354 A GB1425354 A GB 1425354A
Authority
GB
United Kingdom
Prior art keywords
compounds
formula
hypotensive
indole derivatives
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB353174*[A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Priority to GB353174*[A priority Critical patent/GB1425354A/en
Priority to IE1956/74A priority patent/IE40052B1/xx
Priority to CA210,138A priority patent/CA1041512A/en
Priority to DE19742447947 priority patent/DE2447947A1/de
Priority to CH1155378A priority patent/CH613449A5/xx
Priority to CH1155278A priority patent/CH611615A5/xx
Priority to FR7433967A priority patent/FR2247239B1/fr
Priority to JP49115686A priority patent/JPS6039678B2/ja
Priority to CH1155178A priority patent/CH612431A5/xx
Priority to CH1358574A priority patent/CH610323A5/xx
Priority to NLAANVRAGE7413358,A priority patent/NL179731C/xx
Priority to US05/597,841 priority patent/US4177279A/en
Publication of GB1425354A publication Critical patent/GB1425354A/en
Priority to US05/705,647 priority patent/US4061641A/en
Priority to KE2950A priority patent/KE2950A/xx
Priority to HK361/79A priority patent/HK36179A/xx
Priority to MY1979210A priority patent/MY7900210A/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
GB353174*[A 1973-10-10 1974-01-25 Indole derivatives Expired GB1425354A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
GB353174*[A GB1425354A (en) 1973-10-10 1974-01-25 Indole derivatives
IE1956/74A IE40052B1 (en) 1973-10-10 1974-09-23 Indole derivatives
CA210,138A CA1041512A (en) 1973-10-10 1974-09-26 Indole derivatives
DE19742447947 DE2447947A1 (de) 1973-10-10 1974-10-08 Indolderivate und verfahren zu ihrer herstellung
JP49115686A JPS6039678B2 (ja) 1973-10-10 1974-10-09 新規インド−ル誘導体の製法
CH1155278A CH611615A5 (en) 1973-10-10 1974-10-09 Process for the preparation of novel indole derivatives
FR7433967A FR2247239B1 (enrdf_load_stackoverflow) 1973-10-10 1974-10-09
CH1155378A CH613449A5 (en) 1973-10-10 1974-10-09 Process for the preparation of novel indole derivatives
CH1155178A CH612431A5 (en) 1973-10-10 1974-10-09 Process for the preparation of novel indole derivatives
CH1358574A CH610323A5 (en) 1973-10-10 1974-10-09 Process for the preparation of indole derivatives
NLAANVRAGE7413358,A NL179731C (nl) 1973-10-10 1974-10-10 Werkwijze ter bereiding van farmaceutische preparaten met werking op het cardiovasculaire systeem, alsmede een werkwijze voor het bereiden van voor gebruik bij eerstgenoemde werkwijze geschikte 3-piperidinoalkylindoolderivaten en gevormde farmaceutische preparaten.
US05/597,841 US4177279A (en) 1973-10-10 1975-07-21 1-[(3-Indolyl)-alkyl]-piperidyl ureas and hypotensive compositions
US05/705,647 US4061641A (en) 1973-10-10 1976-07-15 Ureidopiperidino-ketoalkyl indoles
KE2950A KE2950A (en) 1973-10-10 1979-04-10 Indole derivatives
HK361/79A HK36179A (en) 1973-10-10 1979-06-07 Indole derivatives
MY1979210A MY7900210A (en) 1973-10-10 1979-12-31 Indole derivatives

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB4720873 1973-10-10
GB353174*[A GB1425354A (en) 1973-10-10 1974-01-25 Indole derivatives
GB727774 1974-02-18

Publications (1)

Publication Number Publication Date
GB1425354A true GB1425354A (en) 1976-02-18

Family

ID=27254287

Family Applications (1)

Application Number Title Priority Date Filing Date
GB353174*[A Expired GB1425354A (en) 1973-10-10 1974-01-25 Indole derivatives

Country Status (10)

Country Link
JP (1) JPS6039678B2 (enrdf_load_stackoverflow)
CH (4) CH610323A5 (enrdf_load_stackoverflow)
DE (1) DE2447947A1 (enrdf_load_stackoverflow)
FR (1) FR2247239B1 (enrdf_load_stackoverflow)
GB (1) GB1425354A (enrdf_load_stackoverflow)
HK (1) HK36179A (enrdf_load_stackoverflow)
IE (1) IE40052B1 (enrdf_load_stackoverflow)
KE (1) KE2950A (enrdf_load_stackoverflow)
MY (1) MY7900210A (enrdf_load_stackoverflow)
NL (1) NL179731C (enrdf_load_stackoverflow)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147786A (en) 1976-02-02 1979-04-03 Ciba-Geigy Corporation 1-Indolylalkyl-3-or 4-trimethyleneurido-piperidines
US4209521A (en) * 1977-12-01 1980-06-24 John Wyeth & Brother Limited Anti-depressant indole derivatives
US4935432A (en) * 1988-01-14 1990-06-19 Fujisawa Pharmaceutical Co., Ltd. Indolylpiperidine compounds, processes for the preparation thereof and pharmaceutical composition comprising the same
WO2001087839A1 (en) * 2000-05-17 2001-11-22 Astrazeneca Ab Pharmaceutically active piperidine derivatives, in particular as modulators of chemokine receptor activity
US6903085B1 (en) 1999-08-24 2005-06-07 Astrazeneca, Ab Substituted piperidine compounds useful as modulators of chemokine receptor activity
US6958350B2 (en) 2001-02-19 2005-10-25 Astrazeneca Ab Chemical compounds
US6960602B2 (en) 2001-03-22 2005-11-01 Astrazeneca Ab Piperidine derivatives as modulators of chemokine receptors
US7192973B2 (en) 2001-11-15 2007-03-20 Astrazeneca Ab Piperidine derivatives and their use as modulators of chemokine receptor activity (especially CCR5)
US7294636B2 (en) 2003-05-09 2007-11-13 Astrazeneca Ab Chemical compounds
US7858789B2 (en) 1999-12-14 2010-12-28 Ipsen Pharma S.A.S. Derivatives of 4-aminopiperidine and their use as a medicament

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1542137A (en) * 1976-03-12 1979-03-14 Wyeth John & Brother Ltd Process for preparing 3(piperidinoalkyl)indoles
JPS56158Y2 (enrdf_load_stackoverflow) * 1976-06-28 1981-01-06
US4242347A (en) 1979-06-18 1980-12-30 Ciba-Geigy Corporation Hypotensive indolylalkylpiperidyl guanidines and isoureas
JPS62157297U (enrdf_load_stackoverflow) * 1986-03-27 1987-10-06

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147786A (en) 1976-02-02 1979-04-03 Ciba-Geigy Corporation 1-Indolylalkyl-3-or 4-trimethyleneurido-piperidines
US4209521A (en) * 1977-12-01 1980-06-24 John Wyeth & Brother Limited Anti-depressant indole derivatives
US4935432A (en) * 1988-01-14 1990-06-19 Fujisawa Pharmaceutical Co., Ltd. Indolylpiperidine compounds, processes for the preparation thereof and pharmaceutical composition comprising the same
US5017703A (en) * 1988-01-14 1991-05-21 Fujisawa Pharmaceutical Company, Ltd. Indolylpiperidine compounds, processes for the preparation thereof and pharmaceutical composition comprising the same
US6903085B1 (en) 1999-08-24 2005-06-07 Astrazeneca, Ab Substituted piperidine compounds useful as modulators of chemokine receptor activity
US7858789B2 (en) 1999-12-14 2010-12-28 Ipsen Pharma S.A.S. Derivatives of 4-aminopiperidine and their use as a medicament
WO2001087839A1 (en) * 2000-05-17 2001-11-22 Astrazeneca Ab Pharmaceutically active piperidine derivatives, in particular as modulators of chemokine receptor activity
US6958350B2 (en) 2001-02-19 2005-10-25 Astrazeneca Ab Chemical compounds
US6960602B2 (en) 2001-03-22 2005-11-01 Astrazeneca Ab Piperidine derivatives as modulators of chemokine receptors
US7192973B2 (en) 2001-11-15 2007-03-20 Astrazeneca Ab Piperidine derivatives and their use as modulators of chemokine receptor activity (especially CCR5)
US7294636B2 (en) 2003-05-09 2007-11-13 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
MY7900210A (en) 1979-12-31
FR2247239B1 (enrdf_load_stackoverflow) 1978-07-21
HK36179A (en) 1979-06-15
FR2247239A1 (enrdf_load_stackoverflow) 1975-05-09
JPS5076076A (enrdf_load_stackoverflow) 1975-06-21
NL7413358A (nl) 1975-04-14
KE2950A (en) 1979-04-27
DE2447947A1 (de) 1975-04-17
CH610323A5 (en) 1979-04-12
IE40052L (en) 1975-04-10
NL179731C (nl) 1986-11-03
NL179731B (nl) 1986-06-02
CH612431A5 (en) 1979-07-31
IE40052B1 (en) 1979-02-28
CH613449A5 (en) 1979-09-28
CH611615A5 (en) 1979-06-15
JPS6039678B2 (ja) 1985-09-06

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee