CH592071A5 - - Google Patents
Info
- Publication number
- CH592071A5 CH592071A5 CH703673A CH703673A CH592071A5 CH 592071 A5 CH592071 A5 CH 592071A5 CH 703673 A CH703673 A CH 703673A CH 703673 A CH703673 A CH 703673A CH 592071 A5 CH592071 A5 CH 592071A5
- Authority
- CH
- Switzerland
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2340972A GB1435721A (en) | 1972-05-18 | 1972-05-18 | Benzoxazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH592071A5 true CH592071A5 (en:Method) | 1977-10-14 |
Family
ID=10195157
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1621375A CH587834A5 (en:Method) | 1972-05-18 | 1973-05-17 | |
| CH703673A CH592071A5 (en:Method) | 1972-05-18 | 1973-05-17 | |
| CH1621275A CH595361A5 (en:Method) | 1972-05-18 | 1973-05-17 | |
| CH1298576A CH595362A5 (en:Method) | 1972-05-18 | 1973-05-17 | |
| CH1298676A CH594643A5 (en:Method) | 1972-05-18 | 1973-05-17 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1621375A CH587834A5 (en:Method) | 1972-05-18 | 1973-05-17 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1621275A CH595361A5 (en:Method) | 1972-05-18 | 1973-05-17 | |
| CH1298576A CH595362A5 (en:Method) | 1972-05-18 | 1973-05-17 | |
| CH1298676A CH594643A5 (en:Method) | 1972-05-18 | 1973-05-17 |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US3912748A (en:Method) |
| JP (6) | JPS5912672B2 (en:Method) |
| KR (1) | KR780000234B1 (en:Method) |
| AR (4) | AR230991A1 (en:Method) |
| AT (1) | AT333752B (en:Method) |
| BE (1) | BE799790A (en:Method) |
| BG (1) | BG21408A3 (en:Method) |
| CA (1) | CA1029019A (en:Method) |
| CH (5) | CH587834A5 (en:Method) |
| CS (1) | CS200455B2 (en:Method) |
| CY (1) | CY1016A (en:Method) |
| DD (1) | DD105229A5 (en:Method) |
| DE (1) | DE2324443A1 (en:Method) |
| DK (1) | DK140340B (en:Method) |
| ES (1) | ES414863A1 (en:Method) |
| FR (2) | FR2184966B1 (en:Method) |
| GB (1) | GB1435721A (en:Method) |
| HK (1) | HK72579A (en:Method) |
| HU (1) | HU167933B (en:Method) |
| IE (2) | IE37564B1 (en:Method) |
| IL (2) | IL42102A (en:Method) |
| KE (1) | KE2975A (en:Method) |
| MY (1) | MY8000063A (en:Method) |
| NL (1) | NL170145C (en:Method) |
| PH (3) | PH9685A (en:Method) |
| PL (3) | PL89247B1 (en:Method) |
| RO (2) | RO66800A (en:Method) |
| SE (3) | SE386174B (en:Method) |
| SU (3) | SU574157A3 (en:Method) |
| YU (3) | YU130473A (en:Method) |
| ZA (1) | ZA732791B (en:Method) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1495488A (en) * | 1976-06-23 | 1977-12-21 | Ippco Int Pharma Patents Co Es | Optically active 2-(2-phenyl-5-benzoxazolyl)propionic acids |
| US4087437A (en) * | 1976-09-07 | 1978-05-02 | Eli Lilly And Company | 2-Phenyl-5-benzoxazolylalkanoic acid purification process |
| GB1590587A (en) * | 1977-06-28 | 1981-06-03 | Lilly Industries Ltd | Benoxaprofen |
| IT1099589B (it) * | 1978-08-04 | 1985-09-18 | Ravizza Spa | Processo per la preparazione di derivati dell'acido benzoxazolil propionico |
| CA1125768A (en) * | 1978-10-31 | 1982-06-15 | Hoffmann-La Roche Limited | Benzoxazole derivatives |
| GR75153B (en:Method) * | 1981-03-27 | 1984-07-13 | Lilly Co Eli | |
| IT1157295B (it) * | 1982-07-19 | 1987-02-11 | Ravizza Spa | Processo perfezionato per la preparazione di derivati dell'acido benzoxazolil propionico |
| DE3413875A1 (de) * | 1984-04-12 | 1985-10-17 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | Benzothiazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltendes arzneimittel |
| IT1177017B (it) * | 1984-10-22 | 1987-08-26 | Ravizza Spa | Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico |
| US4873259A (en) * | 1987-06-10 | 1989-10-10 | Abbott Laboratories | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds |
| US4822809A (en) * | 1987-11-13 | 1989-04-18 | Abbott Laboratories | Benzazole lipoxygenase inhibiting compounds |
| IT1233836B (it) * | 1988-01-13 | 1992-04-21 | Euroresearch Srl | Sali idrosolubili dell'acido (+)2-(4 fluorofenil)-alfa-metil-5 benzoxazolo acetato. |
| UA83620C2 (ru) * | 2001-12-05 | 2008-08-11 | Уайт | Замещенные бензоксазолы и их аналоги как эстрогенные агенты |
| AU2003283597A1 (en) * | 2002-11-16 | 2004-06-15 | Oxford Glycosciences (Uk) Ltd | Benzoxazole, benzthiazole and benzimidazole acid derivatives and their use as heparanase inhibitors |
| JP4790594B2 (ja) * | 2003-02-25 | 2011-10-12 | トポターゲット ユーケー リミテッド | Ｈｄａｃインヒビターとしての、二環式ヘテロアリール基を含むヒドロキサム酸化合物 |
| ME01868B (me) * | 2004-12-15 | 2010-10-31 | Dompe Pha R Ma Spa Res & Mfg | Derivati 2-arilpropionske kiseline i farmaceutske smeše, koje ih sadrže |
| CA2609659C (en) | 2005-05-26 | 2014-01-28 | Neuron Systems, Inc. | Azanaphthalenes, compositions and methods for treating retinal disease |
| JP5369854B2 (ja) | 2008-04-21 | 2013-12-18 | 住友化学株式会社 | 有害節足動物防除組成物および縮合複素環化合物 |
| WO2011072141A1 (en) | 2009-12-11 | 2011-06-16 | Neuron Systems, Inc. | Compositions and methods for the treatment of macular degeneration |
| RU2018145691A (ru) | 2013-01-23 | 2019-04-01 | Альдейра Терапьютикс, Инк. | Заболевания, связанные с токсичным альдегидом, и их лечение |
| MX2015009444A (es) | 2013-01-25 | 2016-04-15 | Aldeyra Therapeutics Inc | Trampas novedosas en el tratamiento de la degeneracion macular. |
| JPWO2016021706A1 (ja) * | 2014-08-08 | 2017-05-25 | カズマパートナーズ株式会社 | 縮合複素環化合物 |
| US10550085B2 (en) | 2015-08-21 | 2020-02-04 | Aldeyra Therapeutics, Inc. | Deuterated compounds and uses thereof |
| AU2017264697A1 (en) | 2016-05-09 | 2018-11-22 | Aldeyra Therapeutics, Inc. | Combination treatment of ocular inflammatory disorders and diseases |
| WO2018170476A1 (en) | 2017-03-16 | 2018-09-20 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| AU2018348174A1 (en) | 2017-10-10 | 2020-04-23 | Aldeyra Therapeutics, Inc. | Treatment of inflammatory disorders |
| US12006298B2 (en) | 2018-08-06 | 2024-06-11 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| CA3113462A1 (en) | 2018-09-25 | 2020-04-02 | Aldeyra Therapeutics, Inc. | Formulations of reproxalap for the treatment of dry eye disease |
| JP7706758B2 (ja) | 2019-03-26 | 2025-07-14 | アルデイラ セラピューティクス， インコーポレイテッド | 眼科用製剤およびその使用 |
| WO2020223717A1 (en) | 2019-05-02 | 2020-11-05 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| CA3137301A1 (en) | 2019-05-02 | 2020-11-05 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| CA3175856A1 (en) | 2020-05-13 | 2021-11-18 | Todd Brady | Pharmaceutical formulations and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD70860A (en:Method) * | ||||
| NL285932A (en:Method) * | 1961-11-27 | |||
| CH516339A (de) * | 1969-03-03 | 1971-12-15 | Ciba Geigy Ag | Verwendung von Azolverbindungen als Antioxydantien |
| DE2118315C3 (de) * | 1970-04-20 | 1975-04-03 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | 2-(1H)-Chinazolinonderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| IL37633A (en) * | 1970-09-10 | 1975-08-31 | Merck & Co Inc | 2-(4-(2-benzoxazolyl)phenyl)alkanoic acid derivatives |
| DE2115926C3 (de) * | 1971-04-01 | 1978-05-03 | C.H. Boehringer Sohn, 6507 Ingelheim | 1 -(4-Hydroxy-3-dimethylaminosuIfamidophenyI)-2-aminoäthanderivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel |
| GB1491863A (en) * | 1973-10-23 | 1977-11-16 | Lilly Industries Ltd | 2,5-or 2,6-disubstituted benzoxazoles |
| GB1590587A (en) * | 1977-06-28 | 1981-06-03 | Lilly Industries Ltd | Benoxaprofen |
-
1972
- 1972-05-18 GB GB2340972A patent/GB1435721A/en not_active Expired
-
1973
- 1973-04-25 IL IL42102A patent/IL42102A/en unknown
- 1973-04-25 IE IE1898/76A patent/IE37564B1/xx unknown
- 1973-04-25 ZA ZA732791A patent/ZA732791B/xx unknown
- 1973-04-28 IE IE648/73A patent/IE37563B1/xx unknown
- 1973-05-01 US US356251A patent/US3912748A/en not_active Expired - Lifetime
- 1973-05-01 CA CA170,186A patent/CA1029019A/en not_active Expired
- 1973-05-07 PH PH14592*UA patent/PH9685A/en unknown
- 1973-05-11 AR AR247979A patent/AR230991A1/es active
- 1973-05-15 DE DE2324443A patent/DE2324443A1/de not_active Ceased
- 1973-05-15 CY CY1016A patent/CY1016A/xx unknown
- 1973-05-16 DD DD170872A patent/DD105229A5/xx unknown
- 1973-05-16 KR KR7300790A patent/KR780000234B1/ko not_active Expired
- 1973-05-16 HU HULI244A patent/HU167933B/hu not_active IP Right Cessation
- 1973-05-16 CS CS733508A patent/CS200455B2/cs unknown
- 1973-05-17 AT AT432573A patent/AT333752B/de not_active IP Right Cessation
- 1973-05-17 YU YU01304/73A patent/YU130473A/xx unknown
- 1973-05-17 CH CH1621375A patent/CH587834A5/xx not_active IP Right Cessation
- 1973-05-17 CH CH703673A patent/CH592071A5/xx not_active IP Right Cessation
- 1973-05-17 DK DK274673AA patent/DK140340B/da not_active IP Right Cessation
- 1973-05-17 SU SU7301916802A patent/SU574157A3/ru active
- 1973-05-17 ES ES414863A patent/ES414863A1/es not_active Expired
- 1973-05-17 FR FR7317894A patent/FR2184966B1/fr not_active Expired
- 1973-05-17 CH CH1621275A patent/CH595361A5/xx not_active IP Right Cessation
- 1973-05-17 CH CH1298576A patent/CH595362A5/xx not_active IP Right Cessation
- 1973-05-17 JP JP48055110A patent/JPS5912672B2/ja not_active Expired
- 1973-05-17 SE SE7307005A patent/SE386174B/xx unknown
- 1973-05-17 CH CH1298676A patent/CH594643A5/xx not_active IP Right Cessation
- 1973-05-18 PL PL1973162653A patent/PL89247B1/pl unknown
- 1973-05-18 RO RO7384621A patent/RO66800A/ro unknown
- 1973-05-18 NL NLAANVRAGE7307018,A patent/NL170145C/xx not_active IP Right Cessation
- 1973-05-18 PL PL1973182614A patent/PL92565B1/pl unknown
- 1973-05-18 PL PL1973183011A patent/PL94208B1/pl unknown
- 1973-05-18 BG BG023657A patent/BG21408A3/xx unknown
- 1973-05-18 BE BE6044169A patent/BE799790A/xx not_active IP Right Cessation
- 1973-05-18 RO RO7374829A patent/RO66278A/ro unknown
-
1974
- 1974-11-21 PH PH16541A patent/PH11718A/en unknown
- 1974-11-21 PH PH16542A patent/PH10704A/en unknown
- 1974-11-29 SU SU7402079274A patent/SU580837A3/ru active
- 1974-11-29 SU SU7402079273A patent/SU582762A3/ru active
-
1975
- 1975-01-01 AR AR257862A patent/AR207857A1/es active
- 1975-01-01 AR AR257863A patent/AR205021A1/es active
- 1975-06-12 FR FR7518361A patent/FR2284592A1/fr active Granted
- 1975-08-22 SE SE7509387A patent/SE434399B/xx not_active IP Right Cessation
- 1975-12-23 IL IL48711A patent/IL48711A0/xx unknown
-
1976
- 1976-03-06 AR AR257861A patent/AR212010A1/es active
-
1977
- 1977-09-21 SE SE7710602A patent/SE435838B/xx not_active IP Right Cessation
-
1979
- 1979-05-17 YU YU01170/79A patent/YU117079A/xx unknown
- 1979-05-17 YU YU1171/79A patent/YU36298B/xx unknown
- 1979-07-03 KE KE2975A patent/KE2975A/xx unknown
- 1979-10-11 HK HK725/79A patent/HK72579A/xx unknown
-
1980
- 1980-12-31 MY MY198063A patent/MY8000063A/xx unknown
-
1981
- 1981-05-13 JP JP7212281A patent/JPS56167674A/ja active Pending
- 1981-05-13 JP JP7212181A patent/JPS56167673A/ja active Pending
- 1981-05-13 JP JP56072123A patent/JPS5929185B2/ja not_active Expired
- 1981-05-13 JP JP7212481A patent/JPS56167675A/ja active Pending
-
1984
- 1984-02-02 JP JP59017637A patent/JPS6021976B2/ja not_active Expired
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |