CH542232A - Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate - Google Patents

Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate

Info

Publication number
CH542232A
CH542232A CH1476972A CH1476972A CH542232A CH 542232 A CH542232 A CH 542232A CH 1476972 A CH1476972 A CH 1476972A CH 1476972 A CH1476972 A CH 1476972A CH 542232 A CH542232 A CH 542232A
Authority
CH
Switzerland
Prior art keywords
preparation
new
oxadiazole derivatives
oxadiazole
derivatives
Prior art date
Application number
CH1476972A
Other languages
German (de)
English (en)
Inventor
Kalman Dr Harsanyi
Jozsef Dipl Ing Reiter
Dezso Dipl Ing Korbonits
Csaba Dipl Ing Gonczi
Kalman Dipl Ing Takacs
Erzsebet Dipl Ing Bako
Gyorgy Dr Med Leszkovszky
Tardos Laszlo
Vertesy Csaba
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CH542232A publication Critical patent/CH542232A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CH1476972A 1968-04-26 1969-04-24 Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate CH542232A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI000796 1968-04-26

Publications (1)

Publication Number Publication Date
CH542232A true CH542232A (de) 1973-11-15

Family

ID=10994349

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1476972A CH542232A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate
CH627569A CH540925A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH627569A CH540925A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten

Country Status (15)

Country Link
US (1) US3647809A (https=)
JP (1) JPS4824394B1 (https=)
AT (2) AT292728B (https=)
BE (1) BE732131A (https=)
BR (1) BR6908381D0 (https=)
CA (1) CA954858A (https=)
CH (2) CH542232A (https=)
DE (1) DE1920037A1 (https=)
FR (1) FR2007529B1 (https=)
GB (1) GB1271302A (https=)
IL (1) IL31990A (https=)
NL (1) NL6906401A (https=)
NO (1) NO124253B (https=)
PL (1) PL79435B1 (https=)
SE (1) SE368576B (https=)

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US3853893A (en) * 1973-04-02 1974-12-10 Squibb & Sons Inc Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles
HU177086B (en) * 1975-06-09 1981-07-28 Eszakmagyar Vegyimuevek Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な1,2,4−オキサジアゾ−ル誘導体
DE3247118A1 (de) * 1982-12-20 1984-06-20 Cassella Ag, 6000 Frankfurt Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
KR100875222B1 (ko) * 1999-08-19 2008-12-19 아스트라제네카 아베 헤테로폴리사이클릭 화합물 및 간접 글루타메이트 수용체길항제로서의 그들의 용도
EP1582519A3 (en) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
MXPA03007513A (es) * 2001-02-21 2004-07-30 Nps Pharma Inc Compuestos heteropoliciclicos y su uso como antagonistas del receptor metabotropico de glutamato.
US7074809B2 (en) 2002-08-09 2006-07-11 Astrazeneca Ab Compounds
US8178570B2 (en) * 2003-04-09 2012-05-15 Exelixis, Inc. Tie-2 modulators and methods of use
AU2004240586A1 (en) * 2003-05-15 2004-12-02 Merck & Co., Inc. 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as S1P receptor agonists
US20060189661A1 (en) * 2003-11-03 2006-08-24 Wagenen Bradford V Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
WO2005060961A2 (en) * 2003-12-18 2005-07-07 Astrazeneca Ab Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd)
JP4958560B2 (ja) * 2003-12-24 2012-06-20 プロシディオン・リミテッド Gpcr受容体作動薬としてのヘテロ環誘導体
WO2005077368A2 (en) * 2004-02-03 2005-08-25 Astrazeneca Ab Treatment of gastro-esophageal reflux disease (gerd)
US8017631B2 (en) * 2005-04-26 2011-09-13 Neurosearch A/S Oxadiazole derivatives and their medical use
IL169855A (en) * 2005-07-25 2014-05-28 Elta Systems Ltd A system and method for locating a receiver location
PL1907382T3 (pl) 2005-07-26 2016-01-29 Bial Portela & Ca Sa Pochodne nitrokatecholowe jako inhibitory COMT
EP1845097A1 (en) * 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
PT2069336E (pt) * 2006-09-07 2013-03-07 Actelion Pharmaceuticals Ltd Derivados de piridin-4-ilo como agentes imunomoduladores
PL2069335T3 (pl) * 2006-09-08 2013-05-31 Actelion Pharmaceuticals Ltd Pochodne pirydyn-3-ylu jako środki immunomodulujące
BRPI0721213B1 (pt) * 2007-01-31 2021-11-09 Bial - Portela & Ca, S.A. Uso de nitrocatecóis substituídos, e embalagem
BRPI0808789A2 (pt) * 2007-03-16 2014-08-12 Actelion Pharmaceuticals Ltd Compostos e composição farmacêutica de derivados aminopiridina e uso destes
PT2195311E (pt) * 2007-08-17 2011-05-25 Actelion Pharmaceuticals Ltd Derivados de piridina como moduladores do receptor s1p1/edg1
MX2010009043A (es) * 2008-02-28 2010-10-25 Bial Portela & Ca Sa Composicion farmaceutica para farmacos poco solubles.
EP2262799B1 (en) * 2008-03-06 2012-07-04 Actelion Pharmaceuticals Ltd. Pyridine compounds
WO2009109872A1 (en) * 2008-03-07 2009-09-11 Actelion Pharmaceuticals Ltd Pyridin-2-yl derivatives as immunomodulating agents
WO2009116882A1 (en) 2008-03-17 2009-09-24 Portela & Ca., S.A. Crystal forms of 5- [3- (2, 5-dichloro-4, 6-dimethyl-1-oxy-pyridine-3-yl) [1,2,3] oxadiazol-5-yl] -3-nit robenzene-1, 2-diol
EP3782991A1 (en) 2008-05-14 2021-02-24 The Scripps Research Institute Novel modulators of sphingosine phosphate receptors
CN105418598B (zh) 2009-02-10 2019-05-17 孟山都技术有限公司 用于控制线虫的组合物和方法
PT2413912T (pt) 2009-04-01 2019-06-11 Bial Portela & Ca Sa Formulações farmacêuticas compreendendo derivados de nitrocatecol e métodos para as produzir
BRPI1016132B8 (pt) * 2009-04-01 2021-05-25 Bial Portela & Ca Sa composição, formulação farmacêutica, processo de obtenção de uma formulação farmacêutica estável
CA2767585C (en) 2009-07-16 2017-09-26 Actelion Pharmaceuticals Ltd Pyridin-4-yl derivatives
MA34910B1 (fr) 2011-01-19 2014-02-01 Actelion Pharmaceuticals Ltd Dérivés de 2-methoxy-pyridin-4-yl
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
JP6456143B2 (ja) 2011-12-13 2019-01-23 ノヴィファーマ,エス.アー. カテコール−o−メチル転移酵素阻害剤を調製するための中間体として有用な化学的化合物
US9232800B2 (en) 2013-02-15 2016-01-12 Monsanto Technology Llc 3,5-disubstituted-4,5-dihydro-1,2,4-oxadiazoles and compositions and methods for controlling nematode pests
RU2017120184A (ru) 2014-11-28 2018-12-28 БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. Лекарства для замедления течения болезни паркинсона
PH12017502097B1 (en) 2015-05-20 2023-05-05 Idorsia Pharmaceuticals Ltd Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL120029C (https=) * 1959-09-29
US3227725A (en) * 1962-04-17 1966-01-04 Union Carbide Corp Certain 3,5-disubstituted 1,2,4-oxadiazole compounds

Also Published As

Publication number Publication date
PL79435B1 (en) 1975-06-30
SE368576B (https=) 1974-07-08
IL31990A0 (en) 1969-06-25
CH540925A (de) 1973-08-31
BE732131A (https=) 1969-10-01
FR2007529B1 (https=) 1973-03-16
NO124253B (https=) 1972-03-27
DE1920037A1 (de) 1970-11-12
AT292728B (de) 1971-09-10
US3647809A (en) 1972-03-07
AT292727B (de) 1971-09-10
JPS4824394B1 (https=) 1973-07-20
IL31990A (en) 1974-05-16
FR2007529A1 (https=) 1970-01-09
NL6906401A (https=) 1969-10-28
CA954858A (en) 1974-09-17
BR6908381D0 (pt) 1973-02-08
GB1271302A (en) 1972-04-19

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