CH540925A - Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten - Google Patents

Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten

Info

Publication number
CH540925A
CH540925A CH627569A CH627569A CH540925A CH 540925 A CH540925 A CH 540925A CH 627569 A CH627569 A CH 627569A CH 627569 A CH627569 A CH 627569A CH 540925 A CH540925 A CH 540925A
Authority
CH
Switzerland
Prior art keywords
preparation
new
oxadiazole derivatives
oxadiazole
derivatives
Prior art date
Application number
CH627569A
Other languages
German (de)
English (en)
Inventor
Kalman Dr Harsanyi
Jozsef Dipl Ing Reiter
Dezso Dipl Ing Korbonits
Casaba Dipl Ing Gonczi
Kalman Dipl Ing Takacs
Erzsebet Dipl Ing Bako
Gyorgy Dr Med Leszkovszky
Tardos Laszlo
Vertesy Csaba
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CH540925A publication Critical patent/CH540925A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
CH627569A 1968-04-26 1969-04-24 Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten CH540925A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI000796 1968-04-26

Publications (1)

Publication Number Publication Date
CH540925A true CH540925A (de) 1973-08-31

Family

ID=10994349

Family Applications (2)

Application Number Title Priority Date Filing Date
CH627569A CH540925A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten
CH1476972A CH542232A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH1476972A CH542232A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate

Country Status (15)

Country Link
US (1) US3647809A (OSRAM)
JP (1) JPS4824394B1 (OSRAM)
AT (2) AT292728B (OSRAM)
BE (1) BE732131A (OSRAM)
BR (1) BR6908381D0 (OSRAM)
CA (1) CA954858A (OSRAM)
CH (2) CH540925A (OSRAM)
DE (1) DE1920037A1 (OSRAM)
FR (1) FR2007529B1 (OSRAM)
GB (1) GB1271302A (OSRAM)
IL (1) IL31990A (OSRAM)
NL (1) NL6906401A (OSRAM)
NO (1) NO124253B (OSRAM)
PL (1) PL79435B1 (OSRAM)
SE (1) SE368576B (OSRAM)

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US3853893A (en) * 1973-04-02 1974-12-10 Squibb & Sons Inc Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles
HU177086B (en) * 1975-06-09 1981-07-28 Eszakmagyar Vegyimuevek Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な1,2,4−オキサジアゾ−ル誘導体
DE3247118A1 (de) * 1982-12-20 1984-06-20 Cassella Ag, 6000 Frankfurt Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
KR100875222B1 (ko) * 1999-08-19 2008-12-19 아스트라제네카 아베 헤테로폴리사이클릭 화합물 및 간접 글루타메이트 수용체길항제로서의 그들의 용도
EP1582519A3 (en) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
IL157491A0 (en) * 2001-02-21 2004-03-28 Nps Pharmeceuticals Inc Heteropolycyclic compounds and pharmaceutical compositions containing the same
CA2495179A1 (en) 2002-08-09 2004-02-19 Astrazeneca Ab Compounds having an activity at metabotropic glutamate receptors
EP1611123B8 (en) * 2003-04-09 2013-11-13 Exelixis, Inc. Tie-2 modulators and methods of use
WO2004103279A2 (en) * 2003-05-15 2004-12-02 Merck & Co., Inc. 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as s1p receptor agonists
US20060189661A1 (en) * 2003-11-03 2006-08-24 Wagenen Bradford V Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
WO2005060961A2 (en) * 2003-12-18 2005-07-07 Astrazeneca Ab Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd)
EP1711491A1 (en) * 2003-12-24 2006-10-18 Prosidion Limited Heterocyclic derivatives as gpcr receptor agonists
WO2005077368A2 (en) * 2004-02-03 2005-08-25 Astrazeneca Ab Treatment of gastro-esophageal reflux disease (gerd)
WO2006114400A1 (en) * 2005-04-26 2006-11-02 Neurosearch A/S Novel oxadiazole derivatives and their medical use
IL169855A (en) * 2005-07-25 2014-05-28 Elta Systems Ltd A system and method for locating a receiver location
KR101370280B1 (ko) 2005-07-26 2014-03-06 바이알 - 포르텔라 앤드 씨에이 에스에이 Comt 억제제로서의 니트로카테콜 유도체
EP1845097A1 (en) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
SI2069336T1 (sl) * 2006-09-07 2013-03-29 Actelion Pharmaceuticals Ltd. Derivati piridin-4-ila kot imunomodulirna sredstva
CL2007002594A1 (es) * 2006-09-08 2008-06-06 Actelion Pharmaceuticals Ltd Compuestos derivados de piridin-3-il, agentes inmunomoduladores; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento de enfermedades asociadas con un sistema inmunologico activado. .
US8524746B2 (en) 2007-01-31 2013-09-03 Bial-Portela & Ca., S.A. Dosage regimen for COMT inhibitors
AU2008227979B2 (en) * 2007-03-16 2014-02-06 Actelion Pharmaceuticals Ltd Amino- pyridine derivatives as S1P1 /EDG1 receptor agonists
MX2010001881A (es) * 2007-08-17 2010-03-10 Actelion Pharmaceuticals Ltd Derivados de piridina como moduladores del receptor s1p1/edg1.
CN101959504A (zh) * 2008-02-28 2011-01-26 比艾尔-坡特拉有限公司 用于难溶性药物的药物组合物
JP5411877B2 (ja) * 2008-03-06 2014-02-12 アクテリオン ファーマシューティカルズ リミテッド ピリジン化合物
HRP20130641T1 (en) * 2008-03-07 2013-08-31 Actelion Pharmaceuticals Ltd. Pyridin-2-yl derivatives as immunomodulating agents
RU2010139315A (ru) 2008-03-17 2012-04-27 Биал - Портела Энд Ка., С.А. (Pt) Кристаллические формы 5-[3-(2,5-дихлор-4,6-диметил-1-окси-пиридин-3-ил)[1,2,4]оксадиазол-5-ил]-3-нитробензол-1,2-диола
MY156381A (en) * 2008-05-14 2016-02-15 Scripps Research Inst Novel modulators of sphingosine phosphate receptors
HUE025314T2 (en) 2009-02-10 2016-02-29 Monsanto Technology Llc Preparations and procedures for controlling nematodes
CA2757418C (en) * 2009-04-01 2021-06-15 Bial - Portela & Ca., S.A. Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same
MX340360B (es) * 2009-04-01 2016-07-07 Bial-Portela & Ca S A Formulaciones farmaceuticas que comprenden derivados de nitrocatecol y metodos para hacer las mismas.
MY153617A (en) 2009-07-16 2015-02-27 Actelion Pharmaceuticals Ltd Pyridin-4-yl derivatives
MX350009B (es) 2011-01-19 2017-08-23 Idorsia Pharmaceuticals Ltd Derivados de 2-metoxi-piridin-4-ilo.
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
JP6456143B2 (ja) 2011-12-13 2019-01-23 ノヴィファーマ,エス.アー. カテコール−o−メチル転移酵素阻害剤を調製するための中間体として有用な化学的化合物
WO2014127195A1 (en) 2013-02-15 2014-08-21 Monsanto Technology Llc 3,5-disubstituted-4,5-dihydro-1,2,4-oxadiazoles for controlling nematode pests
JP2018500300A (ja) 2014-11-28 2018-01-11 ノヴィファーマ,エス.アー. パーキンソン病を遅延させるための医薬
ES2770348T3 (es) 2015-05-20 2020-07-01 Idorsia Pharmaceuticals Ltd Forma cristalina del compuesto (s)-3-{4-[5-(2-ciclopentil-6-metoxi-piridin-4-il)-[1,2,4]oxadiazol-3-il]-2-etil-6-metil-fenoxi}-propano-1,2-diol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL120029C (OSRAM) * 1959-09-29
US3227725A (en) * 1962-04-17 1966-01-04 Union Carbide Corp Certain 3,5-disubstituted 1,2,4-oxadiazole compounds

Also Published As

Publication number Publication date
FR2007529A1 (OSRAM) 1970-01-09
CH542232A (de) 1973-11-15
AT292728B (de) 1971-09-10
BE732131A (OSRAM) 1969-10-01
AT292727B (de) 1971-09-10
US3647809A (en) 1972-03-07
DE1920037A1 (de) 1970-11-12
NO124253B (OSRAM) 1972-03-27
IL31990A (en) 1974-05-16
GB1271302A (en) 1972-04-19
BR6908381D0 (pt) 1973-02-08
NL6906401A (OSRAM) 1969-10-28
FR2007529B1 (OSRAM) 1973-03-16
CA954858A (en) 1974-09-17
IL31990A0 (en) 1969-06-25
SE368576B (OSRAM) 1974-07-08
JPS4824394B1 (OSRAM) 1973-07-20
PL79435B1 (en) 1975-06-30

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