CH462832A - Verfahren zur Herstellung von Benzodiazepinderivaten - Google Patents
Verfahren zur Herstellung von BenzodiazepinderivatenInfo
- Publication number
- CH462832A CH462832A CH1632365A CH1632365A CH462832A CH 462832 A CH462832 A CH 462832A CH 1632365 A CH1632365 A CH 1632365A CH 1632365 A CH1632365 A CH 1632365A CH 462832 A CH462832 A CH 462832A
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- benzodiazepine derivatives
- benzodiazepine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C17/00—Surface treatment of glass, not in the form of fibres or filaments, by coating
- C03C17/34—Surface treatment of glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions
- C03C17/36—Surface treatment of glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions at least one coating being a metal
- C03C17/3602—Surface treatment of glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions at least one coating being a metal the metal being present as a layer
- C03C17/3668—Surface treatment of glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions at least one coating being a metal the metal being present as a layer the multilayer coating having electrical properties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K5/00—Heat-transfer, heat-exchange or heat-storage materials, e.g. refrigerants; Materials for the production of heat or cold by chemical reactions other than by combustion
- C09K5/08—Materials not undergoing a change of physical state when used
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Physics & Mathematics (AREA)
- Combustion & Propulsion (AREA)
- Thermal Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Geochemistry & Mineralogy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
- Moulding By Coating Moulds (AREA)
- Glass Compositions (AREA)
- Surface Treatment Of Glass Fibres Or Filaments (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35891964A | 1964-04-10 | 1964-04-10 | |
| US40019364A | 1964-09-29 | 1964-09-29 | |
| US415793A US3398139A (en) | 1964-04-10 | 1964-12-03 | Process for preparing 2-amino-benzodiazepines |
| US73547568A | 1968-04-09 | 1968-04-09 | |
| US73547668A | 1968-04-09 | 1968-04-09 | |
| US73547968A | 1968-04-09 | 1968-04-09 | |
| US73547868A | 1968-04-09 | 1968-04-09 | |
| US73548468A | 1968-04-09 | 1968-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH462832A true CH462832A (de) | 1968-09-30 |
Family
ID=27575413
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1663268A CH507215A (de) | 1964-04-10 | 1965-04-02 | Verfahren zur Herstellung von Oximen |
| CH461365A CH498844A (de) | 1964-04-10 | 1965-04-02 | Verfahren zur Herstellung von Chinazolin-Derivaten |
| CH1663168A CH507259A (de) | 1964-04-10 | 1965-04-02 | Verfahren zur Herstellung von Chinazolin-Derivaten |
| CH1530468A CH470401A (de) | 1964-04-10 | 1965-09-10 | Verfahren zur Herstellung von Benzodiazepin-Derivaten |
| CH1264065A CH470399A (de) | 1964-04-10 | 1965-09-10 | Verfahren zur Herstellung von Benzodiazepin-Derivaten |
| CH1632365A CH462832A (de) | 1964-04-10 | 1965-11-26 | Verfahren zur Herstellung von Benzodiazepinderivaten |
| CH1632265A CH462177A (de) | 1964-04-10 | 1965-11-26 | Verfahren zur Herstellung von Chinazolinderivaten |
| CH1904268A CH487908A (de) | 1964-04-10 | 1965-11-26 | Verfahren zur Herstellung von Benzodiazepin-Derivaten |
| CH1632465A CH469008A (de) | 1964-04-10 | 1965-11-26 | Verfahren zur Herstellung von Chinazolin-Derivaten |
| CH1904168A CH469722A (de) | 1964-04-10 | 1965-11-26 | Verfahren zur Herstellung von Benzodiazepin-Derivaten |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1663268A CH507215A (de) | 1964-04-10 | 1965-04-02 | Verfahren zur Herstellung von Oximen |
| CH461365A CH498844A (de) | 1964-04-10 | 1965-04-02 | Verfahren zur Herstellung von Chinazolin-Derivaten |
| CH1663168A CH507259A (de) | 1964-04-10 | 1965-04-02 | Verfahren zur Herstellung von Chinazolin-Derivaten |
| CH1530468A CH470401A (de) | 1964-04-10 | 1965-09-10 | Verfahren zur Herstellung von Benzodiazepin-Derivaten |
| CH1264065A CH470399A (de) | 1964-04-10 | 1965-09-10 | Verfahren zur Herstellung von Benzodiazepin-Derivaten |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1632265A CH462177A (de) | 1964-04-10 | 1965-11-26 | Verfahren zur Herstellung von Chinazolinderivaten |
| CH1904268A CH487908A (de) | 1964-04-10 | 1965-11-26 | Verfahren zur Herstellung von Benzodiazepin-Derivaten |
| CH1632465A CH469008A (de) | 1964-04-10 | 1965-11-26 | Verfahren zur Herstellung von Chinazolin-Derivaten |
| CH1904168A CH469722A (de) | 1964-04-10 | 1965-11-26 | Verfahren zur Herstellung von Benzodiazepin-Derivaten |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US3485841A (de) |
| BE (6) | BE662354A (de) |
| BR (5) | BR6568738D0 (de) |
| CH (10) | CH507215A (de) |
| DE (8) | DE1618518A1 (de) |
| DK (7) | DK121123B (de) |
| FI (1) | FI46965C (de) |
| FR (8) | FR1459759A (de) |
| GB (10) | GB1082163A (de) |
| IL (5) | IL23270A (de) |
| MY (2) | MY6800112A (de) |
| NL (8) | NL6504628A (de) |
| NO (4) | NO121607B (de) |
| SE (9) | SE338779B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4238610A (en) * | 1979-12-20 | 1980-12-09 | Hoffmann-La Roche Inc. | Intermediates for the production of imidazobenzodiazepines |
| CA1157855A (en) * | 1980-07-31 | 1983-11-29 | Albert E. Fischli | Benzodiazepine derivatives |
| US4472435A (en) * | 1980-07-31 | 1984-09-18 | Hoffman-La Roche Inc. | Benzophenone derivatives useful in treating heart failure |
| US5326765A (en) * | 1990-02-14 | 1994-07-05 | Ortho Pharmaceutical Corporation | 2,2,4-trialkyl-1,2-dihydroquinazoline-3-oxides |
| US20060019977A1 (en) * | 2002-10-18 | 2006-01-26 | Ono Pharmaceutical Co., Ltd. | Spiroheterocyclic derivative compounds and drugs comprising the compound as the active ingredient |
| US7086167B2 (en) * | 2004-04-16 | 2006-08-08 | Empire Level Mfg. Corp. | Overmolded vial for use with a level |
| CN115108968A (zh) * | 2021-03-23 | 2022-09-27 | 上药康丽（常州）药业有限公司 | 一种3-(4-溴苯基)-哌啶的生产方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3138586A (en) * | 1964-06-23 | Z-cycloalkylamino derivatives of | ||
| US3179656A (en) * | 1965-04-20 | Azepine x-oxidss | ||
| US3311612A (en) * | 1967-03-28 | Process for preparing | ||
| US3267110A (en) * | 1960-06-03 | 1966-08-16 | Smith Kline French Lab | Trifluoromethyl substituted o-aminophenyl ketones |
| US3389176A (en) * | 1961-09-11 | 1968-06-18 | Hoffmann La Roche | 2-aminophenyl-cycloalkyl-ketoximes |
| US3321467A (en) * | 1963-11-27 | 1967-05-23 | Hoffmann La Roche | 3-halo-1, 4-benzodiazepin-2-ones |
| US3398139A (en) * | 1964-04-10 | 1968-08-20 | Hoffmann La Roche | Process for preparing 2-amino-benzodiazepines |
-
1965
- 1965-03-31 IL IL23270A patent/IL23270A/xx unknown
- 1965-04-02 CH CH1663268A patent/CH507215A/de not_active IP Right Cessation
- 1965-04-02 CH CH461365A patent/CH498844A/de not_active IP Right Cessation
- 1965-04-02 CH CH1663168A patent/CH507259A/de not_active IP Right Cessation
- 1965-04-06 DE DE19651618518 patent/DE1618518A1/de active Pending
- 1965-04-06 DE DE19651695193 patent/DE1695193A1/de active Pending
- 1965-04-06 DE DE19651545942 patent/DE1545942A1/de active Pending
- 1965-04-07 BR BR168738/65A patent/BR6568738D0/pt unknown
- 1965-04-08 GB GB14884/65A patent/GB1082163A/en not_active Expired
- 1965-04-08 FR FR12379A patent/FR1459759A/fr not_active Expired
- 1965-04-09 SE SE04688/65A patent/SE338779B/xx unknown
- 1965-04-09 BE BE662354D patent/BE662354A/xx unknown
- 1965-04-09 FR FR12562A patent/FR4621M/fr not_active Expired
- 1965-04-09 DK DK182565AA patent/DK121123B/da unknown
- 1965-04-12 NL NL6504628A patent/NL6504628A/xx unknown
- 1965-09-01 IL IL24258A patent/IL24258A/en unknown
- 1965-09-10 CH CH1530468A patent/CH470401A/de not_active IP Right Cessation
- 1965-09-10 CH CH1264065A patent/CH470399A/de not_active IP Right Cessation
- 1965-09-14 DE DE19651795500 patent/DE1795500A1/de active Pending
- 1965-09-14 DE DE19651545964 patent/DE1545964A1/de active Pending
- 1965-09-17 GB GB39728/65A patent/GB1082164A/en not_active Expired
- 1965-09-17 GB GB7046/66A patent/GB1124829A/en not_active Expired
- 1965-09-24 DK DK492765AA patent/DK120752B/da unknown
- 1965-09-24 FI FI652286A patent/FI46965C/fi active
- 1965-09-27 FR FR32729A patent/FR1447832A/fr not_active Expired
- 1965-09-27 BE BE670133D patent/BE670133A/xx unknown
- 1965-09-28 BR BR173523/65A patent/BR6573523D0/pt unknown
- 1965-09-29 NL NL6512614A patent/NL6512614A/xx unknown
- 1965-09-29 SE SE12612/65A patent/SE318281B/xx unknown
- 1965-09-29 SE SE14586/67A patent/SE318282B/xx unknown
- 1965-11-21 IL IL24659A patent/IL24659A/en unknown
- 1965-11-21 IL IL24658A patent/IL24658A/xx unknown
- 1965-11-26 CH CH1632365A patent/CH462832A/de unknown
- 1965-11-26 CH CH1632265A patent/CH462177A/de unknown
- 1965-11-26 CH CH1904268A patent/CH487908A/de not_active IP Right Cessation
- 1965-11-26 CH CH1632465A patent/CH469008A/de unknown
- 1965-11-26 CH CH1904168A patent/CH469722A/de unknown
- 1965-11-29 DE DE19651545972 patent/DE1545972A1/de active Pending
- 1965-11-29 DE DE19651545974 patent/DE1545974A1/de active Pending
- 1965-11-29 DE DE19651545975 patent/DE1545975A1/de active Pending
- 1965-11-29 NL NL6515499A patent/NL6515499A/xx unknown
- 1965-11-30 FR FR40199A patent/FR4904M/fr not_active Expired
- 1965-11-30 IL IL24703A patent/IL24703A/en unknown
- 1965-11-30 FR FR40200A patent/FR1482840A/fr not_active Expired
- 1965-12-01 SE SE15556/65A patent/SE317384B/xx unknown
- 1965-12-01 GB GB50943/65A patent/GB1124245A/en not_active Expired
- 1965-12-01 SE SE9994/69A patent/SE345455B/xx unknown
- 1965-12-01 BE BE673106D patent/BE673106A/xx unknown
- 1965-12-01 BE BE673109D patent/BE673109A/xx unknown
- 1965-12-01 FR FR40400A patent/FR1476609A/fr not_active Expired
- 1965-12-01 SE SE16559/65A patent/SE320081B/xx unknown
- 1965-12-01 GB GB36216/66A patent/GB1124247A/en not_active Expired
- 1965-12-01 GB GB36215/66A patent/GB1124246A/en not_active Expired
- 1965-12-01 GB GB50941/65A patent/GB1082165A/en not_active Expired
- 1965-12-01 BE BE673108D patent/BE673108A/xx unknown
- 1965-12-01 BE BE673107D patent/BE673107A/xx unknown
- 1965-12-01 SE SE15558/65A patent/SE320080B/xx unknown
- 1965-12-01 GB GB50942/65A patent/GB1082444A/en not_active Expired
- 1965-12-01 GB GB36217/66A patent/GB1124248A/en not_active Expired
- 1965-12-01 SE SE9993/69A patent/SE345458B/xx unknown
- 1965-12-01 GB GB50940/65A patent/GB1124244A/en not_active Expired
- 1965-12-02 NO NO160740A patent/NO121607B/no unknown
- 1965-12-02 NO NO160741A patent/NO120476B/no unknown
- 1965-12-02 BR BR175394/65A patent/BR6575394D0/pt unknown
- 1965-12-02 BR BR175397/65A patent/BR6575397D0/pt unknown
- 1965-12-02 NO NO160742A patent/NO122653B/no unknown
- 1965-12-02 FR FR40552A patent/FR1482841A/fr not_active Expired
- 1965-12-02 BR BR175398/65A patent/BR6575398D0/pt unknown
- 1965-12-02 DK DK621565AA patent/DK117229B/da unknown
- 1965-12-02 FR FR40563A patent/FR1476612A/fr not_active Expired
- 1965-12-03 NL NL6515759A patent/NL131734C/xx active
- 1965-12-03 DK DK624065AA patent/DK125555B/da unknown
- 1965-12-03 NL NL6515758A patent/NL6515758A/xx unknown
-
1966
- 1966-03-29 DK DK163566AA patent/DK115108B/da unknown
- 1966-03-29 DK DK163466AA patent/DK115851B/da unknown
-
1968
- 1968-02-19 NL NL6802319A patent/NL6802319A/xx unknown
- 1968-04-09 US US735478*A patent/US3485841A/en not_active Expired - Lifetime
- 1968-04-09 US US735479*A patent/US3594364A/en not_active Expired - Lifetime
- 1968-04-09 US US735475*A patent/US3503975A/en not_active Expired - Lifetime
- 1968-04-09 US US735484*A patent/US3485823A/en not_active Expired - Lifetime
- 1968-04-09 US US735476*A patent/US3523972A/en not_active Expired - Lifetime
- 1968-12-09 NO NO4919/68A patent/NO121951B/no unknown
- 1968-12-30 MY MY112/68A patent/MY6800112A/xx unknown
-
1969
- 1969-09-18 SE SE12886/69A patent/SE350756B/xx unknown
- 1969-12-31 MY MY1969183A patent/MY6900183A/xx unknown
-
1970
- 1970-05-14 NL NL7006995A patent/NL7006995A/xx unknown
- 1970-05-14 NL NL7006996A patent/NL7006996A/xx unknown
- 1970-06-10 DK DK301070A patent/DK133155C/da active
Also Published As
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