CH388334A - Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten - Google Patents
Verfahren zur Herstellung von basisch substituierten Diphenylalkan-DerivatenInfo
- Publication number
- CH388334A CH388334A CH462964A CH462964A CH388334A CH 388334 A CH388334 A CH 388334A CH 462964 A CH462964 A CH 462964A CH 462964 A CH462964 A CH 462964A CH 388334 A CH388334 A CH 388334A
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- basic substituted
- diphenylalkane
- derivatives
- diphenylalkane derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF25702A DE1111642B (de) | 1958-05-07 | 1958-05-07 | Verfahren zur Herstellung von basisch substituierten Diphenylmethan-Derivaten mit Herz- und Kreislaufwirksamkeit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH388334A true CH388334A (de) | 1965-02-28 |
Family
ID=7091732
Family Applications (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH462964A CH388334A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH463264A CH388329A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH708765A CH397710A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH463164A CH388328A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH462764A CH388332A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH463064A CH396931A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH7291559A CH385878A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH462864A CH388333A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
Family Applications After (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH463264A CH388329A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH708765A CH397710A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH463164A CH388328A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH462764A CH388332A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH463064A CH396931A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH7291559A CH385878A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
| CH462864A CH388333A (de) | 1958-05-07 | 1959-05-05 | Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3152173A (e) |
| BE (1) | BE578515A (e) |
| CH (8) | CH388334A (e) |
| CY (1) | CY277A (e) |
| DE (1) | DE1111642B (e) |
| FR (1) | FR553M (e) |
| GB (1) | GB916644A (e) |
| MY (1) | MY6400049A (e) |
| NL (2) | NL108640C (e) |
| OA (1) | OA01363A (e) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3262977A (en) * | 1962-03-10 | 1966-07-26 | Chinoin Gyogyszer Es Vegyeszet | N-aralkyl-1, 1-diphenyl-propylamine derivatives |
| NL296693A (e) * | 1962-08-16 | |||
| DK111894A (e) | 1962-11-15 | |||
| FR95908E (fr) * | 1963-11-09 | 1972-01-31 | Degussa | Procédé de préparation de nouvelles aminocétones et des alcools secondaires correspondants. |
| DE1231704B (de) | 1963-12-19 | 1967-01-05 | Josef Klosa Dipl Chem Dr Rer N | Verfahren zur Herstellung neuer Diaryl-alkylaminoverbindungen mit heterocyclischen Ringen |
| US3457354A (en) * | 1965-09-21 | 1969-07-22 | Merck & Co Inc | Treatment of hypertension with 2-hydroxy (or amino) - 4,5 - dihydroxyphenethylamine derivatives |
| US3895057A (en) * | 1967-10-13 | 1975-07-15 | Dainippon Pharmaceutical Co | Aminoalkanols and their pharmaceutically acceptable acid-addition salts, and production thereof |
| US4329367A (en) * | 1974-08-05 | 1982-05-11 | Ciba-Geigy Corporation | 1-(Aralkoxyphenyl)-2-(bis-arylalkylamino)-alkanes |
| DE2902172C2 (de) * | 1979-01-20 | 1984-05-10 | UOP Inc., 60016 Des Plaines, Ill. | Verfahren zur Herstellung eines N,N'-Dialkylphenylendiamins |
| EP0105872B1 (en) * | 1982-04-23 | 1988-03-30 | Caola Kozmetikai Es Haztartäsvegyipari Vallalat | Novel cosmetic compositions containing prenylamine and a process for their preparation |
| DE3662521D1 (de) * | 1985-04-16 | 1989-04-27 | Hoffmann La Roche | Phenethanol amine derivatives |
| US6982251B2 (en) * | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
| JP2004517916A (ja) * | 2001-01-26 | 2004-06-17 | シェーリング コーポレイション | ニコチン酸およびその誘導体ならびにステロール吸収阻害剤の併用、および血管適応症の治療 |
| JP2004517919A (ja) * | 2001-01-26 | 2004-06-17 | シェーリング コーポレイション | 血管状態の処置のための心臓血管薬剤とステロール吸収インヒビターとの組み合わせ |
| ME00145B (me) * | 2001-01-26 | 2010-10-10 | Merck Sharp & Dohme | Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije |
| ES2287250T3 (es) * | 2001-01-26 | 2007-12-16 | Schering Corporation | Combinaciones de secuestrante(s) de acidos biliares e inhibidor(es) de la absorcion de esteroles y tratamientos para indicaciones vasculares. |
| US7071181B2 (en) * | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
| IL156445A0 (en) * | 2001-01-26 | 2004-01-04 | Schering Corp | Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications |
| KR20080067717A (ko) * | 2001-01-26 | 2008-07-21 | 쉐링 코포레이션 | 스테롤 흡수 억제제와 혈액 조절제를 포함하는 혈관 질환의치료 또는 예방용 약제학적 조성물 |
| PT1392287E (pt) * | 2001-05-25 | 2007-02-28 | Schering Corp | Métodos para tratamento de doença de alzheimer e/ou regulação dos níveis de peptídeos β amilóide num sujeito |
| ES2272776T3 (es) * | 2001-09-21 | 2007-05-01 | Schering Corporation | Tratamiento de xantomas con derivados de azetidinona como inhibidores de la absorcion de esterol. |
| US7053080B2 (en) * | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
| US7056906B2 (en) * | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
| US20030119808A1 (en) * | 2001-09-21 | 2003-06-26 | Schering Corporation | Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects |
| AU2002335770B2 (en) * | 2001-09-21 | 2005-08-18 | Merck Sharp & Dohme Corp. | Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s) |
| BR0313593A (pt) | 2002-08-19 | 2005-07-12 | Pfizer Prod Inc | Terapia de combinação para doenças hiperproliferativas |
| WO2004043457A1 (en) * | 2002-11-06 | 2004-05-27 | Schering Corporation | Cholesterol absorptions inhibitors for the treatment of autoimmune disorders |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| DE602004018617D1 (de) | 2003-03-07 | 2009-02-05 | Schering Corp | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
| US7192944B2 (en) * | 2003-03-07 | 2007-03-20 | Schering Corp. | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| DE602004016123D1 (de) | 2003-03-07 | 2008-10-09 | Schering Corp | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
| EP1680189A2 (en) * | 2003-11-05 | 2006-07-19 | Schering Corporation | Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions |
| CA2574958A1 (en) * | 2004-07-26 | 2006-02-09 | Cotherix, Inc. | Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation |
| US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| EP1951253A2 (en) * | 2005-10-26 | 2008-08-06 | Cotherix, Inc. | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
| EP2351569B1 (en) | 2005-10-26 | 2012-08-22 | Asahi Kasei Pharma Corporation | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
| CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
| US7879802B2 (en) | 2007-06-04 | 2011-02-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| AU2009256157B2 (en) | 2008-06-04 | 2014-12-18 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011528375A (ja) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2012037665A1 (en) | 2010-09-24 | 2012-03-29 | Oral Delivery Technology Ltd. | Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions |
| AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
| JP2016514671A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼのアゴニストおよびその使用 |
| JP2016516804A (ja) | 2013-04-17 | 2016-06-09 | ファイザー・インク | 心血管疾患を治療するためのn−ピペリジン−3−イルベンズアミド誘導体 |
| AU2014274812B2 (en) | 2013-06-05 | 2018-09-27 | Bausch Health Ireland Limited | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| AU2020209215B2 (en) | 2019-01-18 | 2023-02-02 | Astrazeneca Ab | PCSK9 inhibitors and methods of use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2601323A (en) * | 1949-02-02 | 1952-06-24 | Upjohn Co | Process for preparing 4, 4-diphenyl-6-dimethylamino-heptanone-3 |
| US2681934A (en) * | 1950-01-06 | 1954-06-22 | Commercial Solvents Corp | Substituted diphenylalkylamines |
| US2797242A (en) * | 1953-08-11 | 1957-06-25 | Parke Davis & Co | Substituted alpha-benzylphenethylamines and methods for producing the same |
| US2738347A (en) * | 1954-12-13 | 1956-03-13 | Olin Mathieson | Penicillin salt of benzhydryl-phenethylamine |
| US2872374A (en) * | 1955-02-02 | 1959-02-03 | Nat Drug Co | Muscle-relaxing tranquilizer compositions |
| US2894033A (en) * | 1955-11-15 | 1959-07-07 | Nl Combinatie Chem Ind | Antispasmodic 1, 1-diphenyl-3-dialkylaminopropane, and its tertiary and quaternary salts |
| US2854379A (en) * | 1956-06-06 | 1958-09-30 | Miles Lab | Tranquilizing composition comprising 2-ethyl-cis-crotonylurea |
| DE1058063B (de) * | 1957-02-08 | 1959-05-27 | Hoechst Ag | Verfahren zur Herstellung von analgetisch wirksamen substituierten Phenylaethylaminen |
-
0
- NL NL238796D patent/NL238796A/xx unknown
- NL NL108640D patent/NL108640C/xx active
- BE BE578515D patent/BE578515A/xx unknown
-
1958
- 1958-05-07 DE DEF25702A patent/DE1111642B/de active Pending
-
1959
- 1959-05-05 CH CH462964A patent/CH388334A/de unknown
- 1959-05-05 CH CH463264A patent/CH388329A/de unknown
- 1959-05-05 CH CH708765A patent/CH397710A/de unknown
- 1959-05-05 CH CH463164A patent/CH388328A/de unknown
- 1959-05-05 CH CH462764A patent/CH388332A/de unknown
- 1959-05-05 CH CH463064A patent/CH396931A/de unknown
- 1959-05-05 CH CH7291559A patent/CH385878A/de unknown
- 1959-05-05 US US811011A patent/US3152173A/en not_active Expired - Lifetime
- 1959-05-05 CH CH462864A patent/CH388333A/de unknown
- 1959-05-07 GB GB15785/59A patent/GB916644A/en not_active Expired
-
1960
- 1960-08-31 FR FR837345A patent/FR553M/fr not_active Expired
-
1964
- 1964-02-12 CY CY27764A patent/CY277A/xx unknown
- 1964-12-31 MY MY196449A patent/MY6400049A/xx unknown
- 1964-12-31 OA OA51809A patent/OA01363A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1111642B (de) | 1961-07-27 |
| CH388329A (de) | 1965-02-28 |
| CH385878A (de) | 1964-12-31 |
| CH388332A (de) | 1965-02-28 |
| NL238796A (e) | |
| BE578515A (e) | |
| FR553M (e) | 1961-05-29 |
| OA01363A (fr) | 1969-07-04 |
| MY6400049A (en) | 1964-12-31 |
| CH388333A (de) | 1965-02-28 |
| CH397710A (de) | 1965-08-31 |
| NL108640C (e) | |
| CY277A (en) | 1964-02-12 |
| US3152173A (en) | 1964-10-06 |
| GB916644A (en) | 1963-01-23 |
| CH396931A (de) | 1965-08-15 |
| CH388328A (de) | 1965-02-28 |
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