CH388334A - Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten - Google Patents

Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Info

Publication number
CH388334A
CH388334A CH462964A CH462964A CH388334A CH 388334 A CH388334 A CH 388334A CH 462964 A CH462964 A CH 462964A CH 462964 A CH462964 A CH 462964A CH 388334 A CH388334 A CH 388334A
Authority
CH
Switzerland
Prior art keywords
preparation
basic substituted
diphenylalkane
derivatives
diphenylalkane derivatives
Prior art date
Application number
CH462964A
Other languages
English (en)
Inventor
Ehrhart Gustav Dr Prof
Ott Heinrich
Ernst Dr Lindner
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH388334A publication Critical patent/CH388334A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH462964A 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten CH388334A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF25702A DE1111642B (de) 1958-05-07 1958-05-07 Verfahren zur Herstellung von basisch substituierten Diphenylmethan-Derivaten mit Herz- und Kreislaufwirksamkeit

Publications (1)

Publication Number Publication Date
CH388334A true CH388334A (de) 1965-02-28

Family

ID=7091732

Family Applications (8)

Application Number Title Priority Date Filing Date
CH463064A CH396931A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462764A CH388332A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH7291559A CH385878A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462964A CH388334A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463264A CH388329A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH708765A CH397710A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463164A CH388328A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462864A CH388333A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Family Applications Before (3)

Application Number Title Priority Date Filing Date
CH463064A CH396931A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462764A CH388332A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH7291559A CH385878A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Family Applications After (4)

Application Number Title Priority Date Filing Date
CH463264A CH388329A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH708765A CH397710A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463164A CH388328A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462864A CH388333A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Country Status (10)

Country Link
US (1) US3152173A (de)
BE (1) BE578515A (de)
CH (8) CH396931A (de)
CY (1) CY277A (de)
DE (1) DE1111642B (de)
FR (1) FR553M (de)
GB (1) GB916644A (de)
MY (1) MY6400049A (de)
NL (2) NL108640C (de)
OA (1) OA01363A (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3262977A (en) * 1962-03-10 1966-07-26 Chinoin Gyogyszer Es Vegyeszet N-aralkyl-1, 1-diphenyl-propylamine derivatives
NL296693A (de) * 1962-08-16
FR95908E (fr) * 1963-11-09 1972-01-31 Degussa Procédé de préparation de nouvelles aminocétones et des alcools secondaires correspondants.
US3457354A (en) * 1965-09-21 1969-07-22 Merck & Co Inc Treatment of hypertension with 2-hydroxy (or amino) - 4,5 - dihydroxyphenethylamine derivatives
US3895057A (en) * 1967-10-13 1975-07-15 Dainippon Pharmaceutical Co Aminoalkanols and their pharmaceutically acceptable acid-addition salts, and production thereof
US4329367A (en) * 1974-08-05 1982-05-11 Ciba-Geigy Corporation 1-(Aralkoxyphenyl)-2-(bis-arylalkylamino)-alkanes
DE2902172C2 (de) * 1979-01-20 1984-05-10 UOP Inc., 60016 Des Plaines, Ill. Verfahren zur Herstellung eines N,N'-Dialkylphenylendiamins
JPS59500764A (ja) * 1982-04-23 1984-05-04 カオラ コズメテイカイ エス ハズタルタスベジパリ バララト プレニルアミン含有化粧品組成物
EP0198412B1 (de) * 1985-04-16 1989-03-22 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Phenäthanolaminderivate
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
NZ542090A (en) * 2001-01-26 2006-09-29 Schering Corp Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
EP1785144A3 (de) * 2001-01-26 2007-05-23 Shering Corporation Kombinationen von Gallensäurebinder(n) und Sterolabsorptionshemmer(n) und entsprechende Behandlung für vaskuläre Indikationen
CZ20032031A3 (cs) * 2001-01-26 2003-12-17 Schering Corporation Farmaceutický prostředek
MXPA03006727A (es) * 2001-01-26 2003-10-24 Schering Corp Combinaciones de acido nicotinico y derivados del mismo con inhibidor(es) de la absorcion de los esteroles, y tratamiento para indicaciones vasculares.
SK288217B6 (sk) * 2001-01-26 2014-08-05 Merck Sharp & Dohme Corp. Zmes, terapeutická kombinácia, farmaceutický prostriedok a ich použitie
CA2434430A1 (en) * 2001-01-26 2002-08-01 Harry R. Davis The use of substituted azetidinone compounds for the treatment of sitosterolemia
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
AR038956A1 (es) * 2001-05-25 2005-02-02 Schering Corp Uso de un compuesto que regula la produccion o niveles de peptidos beta amiloides para la manufactura de un medicamento para tratar la enfermedad de alzheimer y/o para regular dichos niveles de peptidos amiloides beta en un sujeto
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
CA2460340C (en) * 2001-09-21 2011-02-15 Schering Corporation Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
PT1427409E (pt) * 2001-09-21 2008-11-27 Schering Corp Métodos para tratar ou para impedir a inflamação vascular utilizando inibidor(es) de absorção de esteróis
GEP20074134B (en) 2002-08-19 2007-06-25 Pfizer Prod Inc Combination therapy for hyperproliferative diseases
WO2004043457A1 (en) * 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
WO2004081004A1 (en) * 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
ATE406364T1 (de) * 2003-03-07 2008-09-15 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
MXPA05009501A (es) 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
US20050096307A1 (en) * 2003-11-05 2005-05-05 Schering Corporation Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
BRPI0513866A (pt) * 2004-07-26 2008-05-20 Cotherix Inc composição, micropartìculas, método para o tratamento da hipertensão pulmonar, e dispositivo de inalação
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
ATE551059T1 (de) * 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
EP2351569B1 (de) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Kombinationstherapie mit Fasudil zur Behandlung von pulmonaler Hypertonie
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2009149279A2 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US8883844B2 (en) 2010-09-24 2014-11-11 Nitrogenix Inc. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
EP2970384A1 (de) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonisten der guanylatcyclase und deren verwendungen
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
CA2909442A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EP3911648A4 (de) 2019-01-18 2022-10-26 Astrazeneca AB Pcsk9-inhibitoren und verfahren zur verwendung davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2601323A (en) * 1949-02-02 1952-06-24 Upjohn Co Process for preparing 4, 4-diphenyl-6-dimethylamino-heptanone-3
US2681934A (en) * 1950-01-06 1954-06-22 Commercial Solvents Corp Substituted diphenylalkylamines
US2797242A (en) * 1953-08-11 1957-06-25 Parke Davis & Co Substituted alpha-benzylphenethylamines and methods for producing the same
US2738347A (en) * 1954-12-13 1956-03-13 Olin Mathieson Penicillin salt of benzhydryl-phenethylamine
US2872374A (en) * 1955-02-02 1959-02-03 Nat Drug Co Muscle-relaxing tranquilizer compositions
US2894033A (en) * 1955-11-15 1959-07-07 Nl Combinatie Chem Ind Antispasmodic 1, 1-diphenyl-3-dialkylaminopropane, and its tertiary and quaternary salts
US2854379A (en) * 1956-06-06 1958-09-30 Miles Lab Tranquilizing composition comprising 2-ethyl-cis-crotonylurea
DE1058063B (de) * 1957-02-08 1959-05-27 Hoechst Ag Verfahren zur Herstellung von analgetisch wirksamen substituierten Phenylaethylaminen

Also Published As

Publication number Publication date
FR553M (de) 1961-05-29
CY277A (en) 1964-02-12
CH397710A (de) 1965-08-31
CH388333A (de) 1965-02-28
NL238796A (de)
CH388328A (de) 1965-02-28
NL108640C (de)
GB916644A (en) 1963-01-23
DE1111642B (de) 1961-07-27
CH396931A (de) 1965-08-15
MY6400049A (en) 1964-12-31
CH388329A (de) 1965-02-28
CH385878A (de) 1964-12-31
BE578515A (de)
US3152173A (en) 1964-10-06
OA01363A (fr) 1969-07-04
CH388332A (de) 1965-02-28

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