CA999866A - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
CA999866A
CA999866A CA102,060A CA102060A CA999866A CA 999866 A CA999866 A CA 999866A CA 102060 A CA102060 A CA 102060A CA 999866 A CA999866 A CA 999866A
Authority
CA
Canada
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA102,060A
Other languages
English (en)
Other versions
CA102060S (en
Inventor
Alfred Rheiner (Jr.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA999866A publication Critical patent/CA999866A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA102,060A 1970-01-06 1971-01-06 Isoquinoline derivatives Expired CA999866A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
CA999866A true CA999866A (en) 1976-11-16

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
CA102,060A Expired CA999866A (en) 1970-01-06 1971-01-06 Isoquinoline derivatives

Country Status (19)

Country Link
JP (1) JPS5515476B1 (forum.php)
AT (1) AT303041B (forum.php)
BE (1) BE761219A (forum.php)
CA (1) CA999866A (forum.php)
CH (2) CH527194A (forum.php)
DE (1) DE2062001C2 (forum.php)
DK (1) DK125021B (forum.php)
ES (1) ES387016A1 (forum.php)
FI (1) FI49503C (forum.php)
FR (1) FR2081412B1 (forum.php)
GB (1) GB1335261A (forum.php)
IE (1) IE34859B1 (forum.php)
IL (1) IL35916A (forum.php)
NL (1) NL171444C (forum.php)
NO (1) NO135315C (forum.php)
PH (1) PH9682A (forum.php)
SE (3) SE368401B (forum.php)
YU (1) YU33660B (forum.php)
ZA (1) ZA708590B (forum.php)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
MXPA02004329A (es) * 1999-11-03 2005-08-26 Amr Technology Inc Tetrahidroisoquinolinas 4-fenil-sustituidas y uso de las mismas para bloquear la recaptacion de norepinefrina, dopamina y serotonina.
DE60038185T2 (de) 1999-11-03 2009-02-19 Amr Technology, Inc. Arly- und heteroaryl-substituierte tetrahydroisoquinoline und ihre verwendung als hemmer der wiederaufnahme von norepinephrin, dopamin und serotonin
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
NZ523456A (en) * 2000-07-11 2004-11-26 Albany Molecular Res Inc Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
CN101119969B (zh) 2004-07-15 2014-04-09 阿尔巴尼分子研究公司 芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和血清素的重摄取的应用
AU2006261162A1 (en) * 2005-06-17 2006-12-28 Janssen Pharmaceutica N.V. Naphthyridine compounds
WO2007011820A2 (en) 2005-07-15 2007-01-25 Amr Technology, Inc. Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
JP5764553B2 (ja) 2009-05-12 2015-08-19 アルバニー モレキュラー リサーチ， インコーポレイテッド ７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンおよびその使用
EP2429295B1 (en) 2009-05-12 2013-12-25 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
CN102638982B (zh) 2009-05-12 2015-07-08 百时美施贵宝公司 (S)-7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉的晶型及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
SE368401B (forum.php) 1974-07-01
IE34859L (en) 1971-07-06
IL35916A (en) 1973-11-28
CH527194A (de) 1972-08-31
IE34859B1 (en) 1975-09-03
AT303041B (de) 1972-11-10
PH9682A (en) 1976-02-10
SE399879B (sv) 1978-03-06
IL35916A0 (en) 1971-02-25
NL171444C (nl) 1983-04-05
DK125021B (da) 1972-12-18
FI49503C (fi) 1975-07-10
JPS5515476B1 (forum.php) 1980-04-23
FR2081412B1 (forum.php) 1974-04-12
SE386672B (sv) 1976-08-16
NL7018956A (forum.php) 1971-07-08
GB1335261A (en) 1973-10-24
YU1971A (en) 1977-06-30
DE2062001C2 (de) 1986-10-16
ZA708590B (en) 1971-09-29
ES387016A1 (es) 1976-05-01
NO135315B (forum.php) 1976-12-13
CH538477A (de) 1973-06-30
FI49503B (forum.php) 1975-04-01
FR2081412A1 (forum.php) 1971-12-03
NO135315C (forum.php) 1977-03-23
YU33660B (en) 1977-12-31
NL171444B (nl) 1982-11-01
BE761219A (fr) 1971-07-05
DE2062001A1 (de) 1971-07-15

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