CA979833A - Enzyme inhibitors of microbial origin - Google Patents

Enzyme inhibitors of microbial origin

Info

Publication number
CA979833A
CA979833A CA130,969A CA130969A CA979833A CA 979833 A CA979833 A CA 979833A CA 130969 A CA130969 A CA 130969A CA 979833 A CA979833 A CA 979833A
Authority
CA
Canada
Prior art keywords
enzyme inhibitors
microbial origin
microbial
origin
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA130,969A
Other languages
English (en)
Other versions
CA130969S (en
Inventor
Werner Frommer
Delf Schmidt
Dietmar Schafer
Walter Puls
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of CA979833A publication Critical patent/CA979833A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces
    • Y10S435/896Streptomyces fradiae
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/907Streptosporangium

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
CA130,969A 1970-12-28 1971-12-23 Enzyme inhibitors of microbial origin Expired CA979833A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2064092A DE2064092C2 (de) 1970-12-28 1970-12-28 Inhibitoren für Glykosidhydrolasen aus Actinomyceten

Publications (1)

Publication Number Publication Date
CA979833A true CA979833A (en) 1975-12-16

Family

ID=5792372

Family Applications (1)

Application Number Title Priority Date Filing Date
CA130,969A Expired CA979833A (en) 1970-12-28 1971-12-23 Enzyme inhibitors of microbial origin

Country Status (28)

Country Link
US (1) US3876766A (nl)
JP (3) JPS5734996B1 (nl)
KR (1) KR780000248B1 (nl)
AR (1) AR193370A1 (nl)
AT (1) AT330122B (nl)
AU (1) AU461521B2 (nl)
BE (1) BE777387A (nl)
BG (3) BG25654A3 (nl)
CA (1) CA979833A (nl)
CH (1) CH594051A5 (nl)
CS (1) CS167961B2 (nl)
DD (1) DD99395A5 (nl)
DE (1) DE2064092C2 (nl)
DK (1) DK139533C (nl)
ES (1) ES398358A1 (nl)
FI (1) FI49774C (nl)
FR (1) FR2120073B1 (nl)
GB (1) GB1374751A (nl)
IE (1) IE35920B1 (nl)
IL (1) IL38441A (nl)
LU (1) LU64319A1 (nl)
NL (1) NL175199C (nl)
NO (1) NO135873C (nl)
PL (1) PL82900B1 (nl)
RO (3) RO63064A (nl)
SE (1) SE398357B (nl)
SU (1) SU454750A3 (nl)
ZA (1) ZA718677B (nl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2209833C3 (de) * 1972-03-01 1978-06-01 Bayer Ag, 5090 Leverkusen Herstellung eines Amylaseinhibitors
DE2209834C3 (de) * 1972-03-01 1978-04-20 Bayer Ag, 5090 Leverkusen Herstellung von Saccharase-Inhibitoren
DE2209832C3 (de) * 1972-03-01 1979-03-29 Bayer Ag, 5090 Leverkusen Herstellung von Saccharaseinhibitoren
US4062950A (en) * 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
US4010258A (en) * 1974-03-15 1977-03-01 Ajinomoto Co., Inc. Microbial amylase inhibitor and preparation thereof with the use of streptomyces diasticus var. amylostaticus
US4065557A (en) * 1974-03-21 1977-12-27 Bayer Aktiengesellschaft Amino sugars and their use in improving the meat:fat ratio in animals
US4065562A (en) * 1975-12-29 1977-12-27 Nippon Shinyaku Co., Ltd. Method and composition for reducing blood glucose levels
FR2338707A1 (fr) * 1976-01-22 1977-08-19 Rhone Poulenc Ind Nouvel inhibiteur de glyco-hydrolases et sa preparation par culture d'un streptomyces
DE2658563A1 (de) * 1976-12-23 1978-06-29 Bayer Ag Inhibitoren fuer glykosid-hydrolasen aus bacillen
DE2701890C2 (de) * 1977-01-19 1983-08-04 Hoechst Ag, 6230 Frankfurt Peptielischer Glycosidhydrolase-Inhibitor aus einem Streptomyceten und seine Verwendung
DE2719912C3 (de) * 1977-05-04 1979-12-06 Bayer Ag, 5090 Leverkusen Verfahren zur Isolierung von 0- |4,6-Dideoxy-4- [JJl S-O,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a -D-glucopyranosyl} -(I Pfeil nach rechts 4)-0- a D-glucopyranosyl-(l Pfeil nach rechts 4)-D-glucopyranose aus Kulturbrühen
GB2016497A (en) * 1978-02-10 1979-09-26 Taisho Pharmaceutical Co Ltd Microbiological production of amylase inhibitor
CA1121290A (en) * 1978-02-14 1982-04-06 Yasuji Suhara Amino sugar derivatives
JPS62160696A (ja) * 1986-01-07 1987-07-16 シャープ株式会社 電子式自動点滅器
EP0257418B1 (de) * 1986-08-13 1993-05-19 Hoechst Aktiengesellschaft Oxiran-Pseudooligosaccharide, Verfahren zu deren Herstellung, deren Verwendung und pharmazeutische Präparate
US5464828A (en) * 1988-03-02 1995-11-07 Chugai Pharmaceutical Co., Ltd. Aqueous suspension of sucralfate
DE19507214A1 (de) * 1995-03-02 1996-10-31 Bayer Ag Acarbose-Biosynthesegene aus Actinoplanes sp., Verfahren zu ihrer Isolierung sowie ihre Verwendung
EP0796915A3 (de) * 1996-03-22 1999-04-14 Bayer Ag Verfahren zur Herstellung sowie zur Verwendung von Acarviosyl-Transferase bei der Umwandlung von Acarbose-Homologen in Acarbose, zur Herstellung von Acarbose-Homologen
DE19637591A1 (de) * 1996-09-13 1998-03-19 Bayer Ag Osmokontrolliertes Fermentationsverfahren zur Herstellung von Acarbose
AU7457300A (en) 1999-10-28 2001-05-08 Chong Kun Dang Pharmaceutical Corp. A process for preparing acarbose with high purity
HRP20010792A2 (en) 2001-10-26 2003-04-30 Pliva D D Acarbose purification process
EP2788373B1 (en) 2011-12-08 2019-01-23 Bayer Intellectual Property GmbH New actinomycete integrative and conjugative element from actinoplanes sp. se50/110 as plasmid for genetic transformation of related actinobacteria
US9345727B2 (en) 2013-03-15 2016-05-24 Mead Johnson Nutrition Company Nutritional compositions containing a peptide component and uses thereof
US9345741B2 (en) 2013-03-15 2016-05-24 Mead Johnson Nutrition Company Nutritional composition containing a peptide component with adiponectin simulating properties and uses thereof
US9138455B2 (en) 2013-03-15 2015-09-22 Mead Johnson Nutrition Company Activating adiponectin by casein hydrolysate
US8889633B2 (en) 2013-03-15 2014-11-18 Mead Johnson Nutrition Company Nutritional compositions containing a peptide component with anti-inflammatory properties and uses thereof
US9289461B2 (en) 2013-03-15 2016-03-22 Mead Johnson Nutrition Company Reducing the risk of autoimmune disease
US9352020B2 (en) 2013-03-15 2016-05-31 Mead Johnson Nutrition Company Reducing proinflammatory response
EP4045520A1 (en) 2019-10-16 2022-08-24 Bayer Aktiengesellschaft Methods for the improved formation of acarbose
MX2022011717A (es) 2020-03-23 2022-12-07 Bay State Milling Company Prueba rapida de pureza de semilla de trigo con alta amilosa.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3127315A (en) * 1964-03-31 Hypocholesterolemic agent m-

Also Published As

Publication number Publication date
GB1374751A (en) 1974-11-20
FI49774C (fi) 1975-10-10
PL82900B1 (nl) 1975-10-31
US3876766A (en) 1975-04-08
BG25654A3 (nl) 1978-11-10
JPS57150395A (en) 1982-09-17
LU64319A1 (nl) 1972-06-13
ES398358A1 (es) 1974-09-01
IE35920B1 (en) 1976-06-23
JPS6234396B2 (nl) 1987-07-27
RO63065A (fr) 1979-02-15
AR193370A1 (es) 1973-04-23
DK139533B (da) 1979-03-05
JPS6216638B2 (nl) 1987-04-14
IE35920L (en) 1972-06-28
DK139533C (da) 1979-08-20
IL38441A0 (en) 1972-02-29
CS167961B2 (nl) 1976-05-28
SE398357B (sv) 1977-12-19
AU3721471A (en) 1973-09-27
DD99395A5 (nl) 1973-08-05
JPS5734996B1 (nl) 1982-07-26
AT330122B (de) 1976-06-10
DE2064092C2 (de) 1983-06-01
RO61400A (nl) 1977-01-15
CH594051A5 (nl) 1977-12-30
ZA718677B (en) 1972-09-27
ATA1111571A (de) 1975-09-15
FR2120073A1 (nl) 1972-08-11
FR2120073B1 (nl) 1975-12-26
NO135873B (nl) 1977-03-07
RO63064A (fr) 1978-06-15
NL175199C (nl) 1984-10-01
KR780000248B1 (en) 1978-07-06
AU461521B2 (en) 1975-05-29
BG26002A4 (nl) 1979-01-12
BG26003A4 (nl) 1979-01-12
FI49774B (nl) 1975-06-30
DE2064092A1 (de) 1972-07-20
JPS57150396A (en) 1982-09-17
BE777387A (fr) 1972-06-28
NL175199B (nl) 1984-05-01
IL38441A (en) 1974-10-22
NO135873C (nl) 1977-06-15
NL7117893A (nl) 1972-06-30
SU454750A3 (ru) 1974-12-25

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