FR2338707A1 - Nouvel inhibiteur de glyco-hydrolases et sa preparation par culture d'un streptomyces - Google Patents

Nouvel inhibiteur de glyco-hydrolases et sa preparation par culture d'un streptomyces

Info

Publication number
FR2338707A1
FR2338707A1 FR7601647A FR7601647A FR2338707A1 FR 2338707 A1 FR2338707 A1 FR 2338707A1 FR 7601647 A FR7601647 A FR 7601647A FR 7601647 A FR7601647 A FR 7601647A FR 2338707 A1 FR2338707 A1 FR 2338707A1
Authority
FR
France
Prior art keywords
streptomyces
culture
preparation
hydrolase inhibitor
new glyco
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7601647A
Other languages
English (en)
Other versions
FR2338707B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7601647A priority Critical patent/FR2338707A1/fr
Priority to NL7700384A priority patent/NL7700384A/xx
Priority to GB2359/77A priority patent/GB1518633A/en
Priority to BE174302A priority patent/BE850653A/fr
Priority to US05/760,978 priority patent/US4271067A/en
Priority to CH78077A priority patent/CH618606A5/fr
Priority to DE19772702417 priority patent/DE2702417A1/de
Priority to JP631777A priority patent/JPS52114096A/ja
Publication of FR2338707A1 publication Critical patent/FR2338707A1/fr
Application granted granted Critical
Publication of FR2338707B1 publication Critical patent/FR2338707B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/823—Lower fungi, e.g. mold
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/823—Lower fungi, e.g. mold
    • Y10S530/824—Yeasts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR7601647A 1976-01-22 1976-01-22 Nouvel inhibiteur de glyco-hydrolases et sa preparation par culture d'un streptomyces Granted FR2338707A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR7601647A FR2338707A1 (fr) 1976-01-22 1976-01-22 Nouvel inhibiteur de glyco-hydrolases et sa preparation par culture d'un streptomyces
NL7700384A NL7700384A (nl) 1976-01-22 1977-01-14 Glycohydrolase-remmer alsmede werkwijze om deze te bereiden.
GB2359/77A GB1518633A (en) 1976-01-22 1977-01-20 Glycopeptide
US05/760,978 US4271067A (en) 1976-01-22 1977-01-21 Glycopeptide
BE174302A BE850653A (fr) 1976-01-22 1977-01-21 Nouvel inhibiteur de glyco-hydrolases et sa preparation par culture d'un streptomyces
CH78077A CH618606A5 (fr) 1976-01-22 1977-01-21
DE19772702417 DE2702417A1 (de) 1976-01-22 1977-01-21 Neuer glyko-hydrolasen-inhibitor und dessen herstellung durch kultur eines streptomyces
JP631777A JPS52114096A (en) 1976-01-22 1977-01-22 Glycopeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7601647A FR2338707A1 (fr) 1976-01-22 1976-01-22 Nouvel inhibiteur de glyco-hydrolases et sa preparation par culture d'un streptomyces

Publications (2)

Publication Number Publication Date
FR2338707A1 true FR2338707A1 (fr) 1977-08-19
FR2338707B1 FR2338707B1 (fr) 1979-10-05

Family

ID=9168223

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7601647A Granted FR2338707A1 (fr) 1976-01-22 1976-01-22 Nouvel inhibiteur de glyco-hydrolases et sa preparation par culture d'un streptomyces

Country Status (8)

Country Link
US (1) US4271067A (fr)
JP (1) JPS52114096A (fr)
BE (1) BE850653A (fr)
CH (1) CH618606A5 (fr)
DE (1) DE2702417A1 (fr)
FR (1) FR2338707A1 (fr)
GB (1) GB1518633A (fr)
NL (1) NL7700384A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2416949A1 (fr) * 1978-02-10 1979-09-07 Taisho Pharmaceutical Co Ltd Procede de preparation d'inhibiteurs d'amylase, nouveaux produits ainsi obtenus et leurs utilisations pharmaceutiques, notamment pour combattre l'obesite et l'hyperglycemie
EP0073428A2 (fr) * 1981-09-01 1983-03-09 Bayer Ag Préparations pharmaceutiques pour des inhibiteurs de glycosidehydrolases

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2701890C2 (de) * 1977-01-19 1983-08-04 Hoechst Ag, 6230 Frankfurt Peptielischer Glycosidhydrolase-Inhibitor aus einem Streptomyceten und seine Verwendung
JPS5910193B2 (ja) * 1980-06-04 1984-03-07 富士レビオ株式会社 アミラ−ゼ阻害物質ａｉ−ｂの製造法
EP0075604A1 (fr) * 1981-09-24 1983-04-06 Asahi Kasei Kogyo Kabushiki Kaisha Agent abaissant la teneur en glucose du sang
DE3346138A1 (de) * 1983-12-21 1985-07-11 Boehringer Mannheim Gmbh, 6800 Mannheim Bacillus thuringiensis var. tenebrionis sowie ein insektizid wirkendes, hieraus erhaeltliches praeparat bzw. toxin sowie deren verwendung zur bekaempfung von coleoptera
JPS6434264A (en) * 1987-07-30 1989-02-03 Yakurigaku Chuo Kenkyusho Kk Feeds and drinks incorporated with digestive enzyme-inhibiting substance separated from grains and beans

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (de) * 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Inhibitoren für Glykosidhydrolasen aus Actinomyceten
JPS5111197B1 (fr) * 1971-05-31 1976-04-09

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2416949A1 (fr) * 1978-02-10 1979-09-07 Taisho Pharmaceutical Co Ltd Procede de preparation d'inhibiteurs d'amylase, nouveaux produits ainsi obtenus et leurs utilisations pharmaceutiques, notamment pour combattre l'obesite et l'hyperglycemie
EP0073428A2 (fr) * 1981-09-01 1983-03-09 Bayer Ag Préparations pharmaceutiques pour des inhibiteurs de glycosidehydrolases
EP0073428A3 (en) * 1981-09-01 1983-08-24 Bayer Ag Medicinal preparations for glycoside-hydrolase inhibitors

Also Published As

Publication number Publication date
US4271067A (en) 1981-06-02
CH618606A5 (fr) 1980-08-15
FR2338707B1 (fr) 1979-10-05
DE2702417A1 (de) 1977-07-28
BE850653A (fr) 1977-07-22
NL7700384A (nl) 1977-07-26
GB1518633A (en) 1978-07-19
JPS52114096A (en) 1977-09-24

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Legal Events

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ST Notification of lapse