CA954858A - Pyridyl oxadiazole derivatives and process for the preparation thereof and pharmaceutical compositions containing same - Google Patents

Pyridyl oxadiazole derivatives and process for the preparation thereof and pharmaceutical compositions containing same

Info

Publication number
CA954858A
CA954858A CA049,755A CA49755A CA954858A CA 954858 A CA954858 A CA 954858A CA 49755 A CA49755 A CA 49755A CA 954858 A CA954858 A CA 954858A
Authority
CA
Canada
Prior art keywords
pyridyl
preparation
pharmaceutical compositions
compositions containing
containing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA049,755A
Other languages
English (en)
Inventor
Csaba Gonczi
Gyorgy Leszkovszky
Erzsebet Bako
Kalman Takacs
Kalman Harsanyi
Dezso Korbonits
Csaba Vertesy
Jozsef Reiter
Laszlo Tardos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Application granted granted Critical
Publication of CA954858A publication Critical patent/CA954858A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CA049,755A 1968-04-26 1969-04-25 Pyridyl oxadiazole derivatives and process for the preparation thereof and pharmaceutical compositions containing same Expired CA954858A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI000796 1968-04-26

Publications (1)

Publication Number Publication Date
CA954858A true CA954858A (en) 1974-09-17

Family

ID=10994349

Family Applications (1)

Application Number Title Priority Date Filing Date
CA049,755A Expired CA954858A (en) 1968-04-26 1969-04-25 Pyridyl oxadiazole derivatives and process for the preparation thereof and pharmaceutical compositions containing same

Country Status (15)

Country Link
US (1) US3647809A (cs)
JP (1) JPS4824394B1 (cs)
AT (2) AT292727B (cs)
BE (1) BE732131A (cs)
BR (1) BR6908381D0 (cs)
CA (1) CA954858A (cs)
CH (2) CH542232A (cs)
DE (1) DE1920037A1 (cs)
FR (1) FR2007529B1 (cs)
GB (1) GB1271302A (cs)
IL (1) IL31990A (cs)
NL (1) NL6906401A (cs)
NO (1) NO124253B (cs)
PL (1) PL79435B1 (cs)
SE (1) SE368576B (cs)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853893A (en) * 1973-04-02 1974-12-10 Squibb & Sons Inc Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles
HU177086B (en) * 1975-06-09 1981-07-28 Eszakmagyar Vegyimuevek Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な１，２，４−オキサジアゾ−ル誘導体
DE3247118A1 (de) * 1982-12-20 1984-06-20 Cassella Ag, 6000 Frankfurt Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP1210344B1 (en) * 1999-08-19 2005-10-19 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
EP1582519A3 (en) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
ATE375340T1 (de) * 2001-02-21 2007-10-15 Nps Pharma Inc Heteropolycyclische verbindungen und deren verwendung als metabotrope glutamatrezeptorantagonisten
AU2003264018A1 (en) 2002-08-09 2004-02-25 Astrazeneca Ab Compounds having an activity at metabotropic glutamate receptors
WO2004091480A2 (en) * 2003-04-09 2004-10-28 Exelixis, Inc. Tie-2 modulators and methods of use
AU2004240586A1 (en) * 2003-05-15 2004-12-02 Merck & Co., Inc. 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as S1P receptor agonists
US20060189661A1 (en) * 2003-11-03 2006-08-24 Wagenen Bradford V Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
WO2005060961A2 (en) * 2003-12-18 2005-07-07 Astrazeneca Ab Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd)
KR101154830B1 (ko) * 2003-12-24 2012-06-18 프로시디온 리미티드 Ｇｐｃｒ 수용체 효능제로서의 헤테로사이클릭 유도체
WO2005077368A2 (en) * 2004-02-03 2005-08-25 Astrazeneca Ab Treatment of gastro-esophageal reflux disease (gerd)
CA2606087A1 (en) 2005-04-26 2006-11-02 Neurosearch A/S Novel oxadiazole derivatives and their medical use
IL169855A (en) * 2005-07-25 2014-05-28 Elta Systems Ltd A system and method for locating a receiver location
US8168793B2 (en) 2005-07-26 2012-05-01 Portela & Ca., S.A. Nitrocatechol derivatives as COMT inhibitors
EP1845097A1 (en) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
RU2447071C2 (ru) * 2006-09-07 2012-04-10 Актелион Фармасьютиклз Лтд Производные пиридин-4-ила в качестве иммуномодулирующих агентов
ES2400163T3 (es) * 2006-09-08 2013-04-08 Actelion Pharmaceuticals Ltd. Derivados de piridil-3-ilo como agentes de inmunomodulación
US8524746B2 (en) 2007-01-31 2013-09-03 Bial-Portela & Ca., S.A. Dosage regimen for COMT inhibitors
PL2125797T3 (pl) * 2007-03-16 2014-06-30 Actelion Pharmaceuticals Ltd Pochodne aminopirydyny jako agoniści receptora S1P1/EDG1
MY153975A (en) * 2007-08-17 2015-04-30 Actelion Pharmaceuticals Ltd Pyridine derivatives as s1p1/edg1 receptor modulators
BRPI0908340A2 (pt) * 2008-02-28 2018-12-26 Bial Portela & Ca Sa composição farmacêutica para fármacos pouco solúveis
EP2262799B1 (en) * 2008-03-06 2012-07-04 Actelion Pharmaceuticals Ltd. Pyridine compounds
US8575200B2 (en) * 2008-03-07 2013-11-05 Actelion Pharmaceuticals Ltd Pyridin-2-yl derivatives as immunomodulating agents
JP2011514380A (ja) 2008-03-17 2011-05-06 バイアル−ポルテラ アンド シーエー，エス．エー． ５−［３−（２，５−ジクロロ−４，６−ジメチル−１−オキシ−ピリジン−３−イル）［１，２，４］オキサジアゾール−５−イル］−３−ニトロベンゼン−１，２−ジオールの結晶形
FI2291080T5 (fi) 2008-05-14 2023-11-06 The Scripps Research Institute Uusia sfingosiinifosfaattireseptorimodulaattoreita
US8017555B2 (en) 2009-02-10 2011-09-13 Divergence, Inc. Compositions and methods for controlling nematodes
EP2413913B1 (en) * 2009-04-01 2022-05-18 Bial-Portela & CA, S.A. Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same
KR20120027197A (ko) 2009-04-01 2012-03-21 바이알 - 포르텔라 앤드 씨에이 에스에이 니트로카테콜 유도체를 포함하는 제약 제제 및 그의 제조 방법
EP2454255B1 (en) 2009-07-16 2013-11-06 Actelion Pharmaceuticals Ltd. Pyridin-4-yl derivatives as s1p1/edg1 agonists
JP5859570B2 (ja) 2011-01-19 2016-02-10 アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ ２−メトキシ−ピリジン−４−イル誘導体
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
WO2013089573A1 (en) 2011-12-13 2013-06-20 BIAL - PORTELA & Cª., S.A. Chemical compound useful as intermediate for preparing a catechol-o-methyltransferase inhibitor
UY35327A (es) * 2013-02-15 2014-09-30 Monsanto Technology Llc ?4,5-dihidro-1,2,4-oxadiazoles disustituidos en 3,5 y composiciones y métodos para controlar plagas de nematodos?.
JP2018500300A (ja) 2014-11-28 2018-01-11 ノヴィファーマ，エス．アー． パーキンソン病を遅延させるための医薬
KR20200044155A (ko) 2015-05-20 2020-04-28 이도르시아 파마슈티컬스 리미티드 화합물 (s)-3-｛4-[5-(2-시클로펜틸-6-메톡시-피리딘-4-일)-[1,2,4]옥사디아졸-3-일]-2-에틸-6-메틸-페녹시｝-프로판-1,2-디올의 결정형

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL120029C (cs) * 1959-09-29
US3227725A (en) * 1962-04-17 1966-01-04 Union Carbide Corp Certain 3,5-disubstituted 1,2,4-oxadiazole compounds

Also Published As

Publication number Publication date
GB1271302A (en) 1972-04-19
FR2007529A1 (cs) 1970-01-09
NO124253B (cs) 1972-03-27
IL31990A0 (en) 1969-06-25
BR6908381D0 (pt) 1973-02-08
NL6906401A (cs) 1969-10-28
JPS4824394B1 (cs) 1973-07-20
AT292728B (de) 1971-09-10
CH542232A (de) 1973-11-15
DE1920037A1 (de) 1970-11-12
BE732131A (cs) 1969-10-01
CH540925A (de) 1973-08-31
US3647809A (en) 1972-03-07
SE368576B (cs) 1974-07-08
PL79435B1 (en) 1975-06-30
IL31990A (en) 1974-05-16
AT292727B (de) 1971-09-10
FR2007529B1 (cs) 1973-03-16

Similar Documents

Publication Publication Date Title
CA954858A (en) Pyridyl oxadiazole derivatives and process for the preparation thereof and pharmaceutical compositions containing same
IL26603A (en) Thiazole derivatives,preparation thereof and pharmaceutical compositions containing them
IL35847A0 (en) New evomonoside derivatives,process for the preparation thereof and pharmaceutical compositions containing the same
IL32481A0 (en) Diphenylmethoxyethylamine derivatives,their preparation and pharmaceutical compositions containing them
IL32841A0 (en) Oxadiazole derivatives,their preparation and pharmaceutical compositions containing them
CA968355A (en) Apovincaminic acid derivatives and process for the preparation thereof
CA956635A (en) 4-quinazolone derivatives and process for the preparation thereof
IL31452A0 (en) 1-amino-3-hydroxy-guanidine derivatives,their preparation and pharmaceutical compositions containing them
CA798865A (en) 5-nitrofuran and 5-nitrothiophene derivatives, process for their preparation, and compositions thereof
CA948645A (en) Nitrofurane derivatives, pharmaceutical and veterinary compositions containing same and process for the preparation thereof
CA949068A (en) Nitrofurane derivatives and process for the preparation thereof
AU446434B2 (en) Substituted aminopyridines and process for the preparation thereof
CA704661A (en) Process for the preparation of benzotriazole derivatives and pharmaceutical compositions containing them
AU425534B2 (en) Novel gona-4, 9, 11-trienes, processes for their preparation, and pharmaceutical compositions incorporating them
CA787440A (en) 6-hydrazino-pyridazine derivatives and process for their preparation
CA798291A (en) Pharmaceutical composition against cephalalgia
AU434967B2 (en) Pharmaceutical preparation and process for its manufacture
AU445963B2 (en) 5-thiazole, carboxylic acid derivatives, process for the preparation thereof and pharmaceutical compositions containing same
AU429504B2 (en) Novel thiazole derivatives, the preparation thereof and compositions containing the same
AU429766B2 (en) New homopyrimidazole derivatives, process forthe preparation thereof and pharmaceutical compositions containing same
CA779897A (en) Process for the preparation of pyridoxine
AU5797069A (en) Substituted aminopyridines and process for the preparation thereof
CA799505A (en) N-aminoalkylated heterocyclic derivatives and the process of preparation thereof
CA778790A (en) Process for the preparation of complex n-substituted azabicyclononanes
CA775585A (en) Bisoxyphenyl compounds and processes for their preparation thereof