IL31990A - Pyridyl 1,2,4-oxadiazole derivatives,process for the preparation thereof and pharmaceutical compositions containing same - Google Patents
Pyridyl 1,2,4-oxadiazole derivatives,process for the preparation thereof and pharmaceutical compositions containing sameInfo
- Publication number
- IL31990A IL31990A IL31990A IL3199069A IL31990A IL 31990 A IL31990 A IL 31990A IL 31990 A IL31990 A IL 31990A IL 3199069 A IL3199069 A IL 3199069A IL 31990 A IL31990 A IL 31990A
- Authority
- IL
- Israel
- Prior art keywords
- pyridyl
- preparation
- pharmaceutical compositions
- compositions containing
- containing same
- Prior art date
Links
- ZAAIEOSUVDRLGD-UHFFFAOYSA-N 3-pyridin-2-yl-1,2,4-oxadiazole Chemical class O1C=NC(C=2N=CC=CC=2)=N1 ZAAIEOSUVDRLGD-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI000796 | 1968-04-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL31990A0 IL31990A0 (en) | 1969-06-25 |
| IL31990A true IL31990A (en) | 1974-05-16 |
Family
ID=10994349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL31990A IL31990A (en) | 1968-04-26 | 1969-04-08 | Pyridyl 1,2,4-oxadiazole derivatives,process for the preparation thereof and pharmaceutical compositions containing same |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3647809A (cs) |
| JP (1) | JPS4824394B1 (cs) |
| AT (2) | AT292727B (cs) |
| BE (1) | BE732131A (cs) |
| BR (1) | BR6908381D0 (cs) |
| CA (1) | CA954858A (cs) |
| CH (2) | CH542232A (cs) |
| DE (1) | DE1920037A1 (cs) |
| FR (1) | FR2007529B1 (cs) |
| GB (1) | GB1271302A (cs) |
| IL (1) | IL31990A (cs) |
| NL (1) | NL6906401A (cs) |
| NO (1) | NO124253B (cs) |
| PL (1) | PL79435B1 (cs) |
| SE (1) | SE368576B (cs) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853893A (en) * | 1973-04-02 | 1974-12-10 | Squibb & Sons Inc | Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles |
| HU177086B (en) * | 1975-06-09 | 1981-07-28 | Eszakmagyar Vegyimuevek | Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives |
| JPS58150576A (ja) * | 1982-03-03 | 1983-09-07 | Sumitomo Chem Co Ltd | 新規な１，２，４−オキサジアゾ−ル誘導体 |
| DE3247118A1 (de) * | 1982-12-20 | 1984-06-20 | Cassella Ag, 6000 Frankfurt | Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| EP1210344B1 (en) * | 1999-08-19 | 2005-10-19 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| US6660753B2 (en) * | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| EP1582519A3 (en) * | 1999-08-19 | 2005-12-21 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| ATE375340T1 (de) * | 2001-02-21 | 2007-10-15 | Nps Pharma Inc | Heteropolycyclische verbindungen und deren verwendung als metabotrope glutamatrezeptorantagonisten |
| AU2003264018A1 (en) | 2002-08-09 | 2004-02-25 | Astrazeneca Ab | Compounds having an activity at metabotropic glutamate receptors |
| WO2004091480A2 (en) * | 2003-04-09 | 2004-10-28 | Exelixis, Inc. | Tie-2 modulators and methods of use |
| AU2004240586A1 (en) * | 2003-05-15 | 2004-12-02 | Merck & Co., Inc. | 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as S1P receptor agonists |
| US20060189661A1 (en) * | 2003-11-03 | 2006-08-24 | Wagenen Bradford V | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| WO2005060961A2 (en) * | 2003-12-18 | 2005-07-07 | Astrazeneca Ab | Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd) |
| KR101154830B1 (ko) * | 2003-12-24 | 2012-06-18 | 프로시디온 리미티드 | Ｇｐｃｒ 수용체 효능제로서의 헤테로사이클릭 유도체 |
| WO2005077368A2 (en) * | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
| CA2606087A1 (en) | 2005-04-26 | 2006-11-02 | Neurosearch A/S | Novel oxadiazole derivatives and their medical use |
| IL169855A (en) * | 2005-07-25 | 2014-05-28 | Elta Systems Ltd | A system and method for locating a receiver location |
| US8168793B2 (en) | 2005-07-26 | 2012-05-01 | Portela & Ca., S.A. | Nitrocatechol derivatives as COMT inhibitors |
| EP1845097A1 (en) | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
| RU2447071C2 (ru) * | 2006-09-07 | 2012-04-10 | Актелион Фармасьютиклз Лтд | Производные пиридин-4-ила в качестве иммуномодулирующих агентов |
| ES2400163T3 (es) * | 2006-09-08 | 2013-04-08 | Actelion Pharmaceuticals Ltd. | Derivados de piridil-3-ilo como agentes de inmunomodulación |
| US8524746B2 (en) | 2007-01-31 | 2013-09-03 | Bial-Portela & Ca., S.A. | Dosage regimen for COMT inhibitors |
| PL2125797T3 (pl) * | 2007-03-16 | 2014-06-30 | Actelion Pharmaceuticals Ltd | Pochodne aminopirydyny jako agoniści receptora S1P1/EDG1 |
| MY153975A (en) * | 2007-08-17 | 2015-04-30 | Actelion Pharmaceuticals Ltd | Pyridine derivatives as s1p1/edg1 receptor modulators |
| BRPI0908340A2 (pt) * | 2008-02-28 | 2018-12-26 | Bial Portela & Ca Sa | composição farmacêutica para fármacos pouco solúveis |
| EP2262799B1 (en) * | 2008-03-06 | 2012-07-04 | Actelion Pharmaceuticals Ltd. | Pyridine compounds |
| US8575200B2 (en) * | 2008-03-07 | 2013-11-05 | Actelion Pharmaceuticals Ltd | Pyridin-2-yl derivatives as immunomodulating agents |
| JP2011514380A (ja) | 2008-03-17 | 2011-05-06 | バイアル−ポルテラ アンド シーエー，エス．エー． | ５−［３−（２，５−ジクロロ−４，６−ジメチル−１−オキシ−ピリジン−３−イル）［１，２，４］オキサジアゾール−５−イル］−３−ニトロベンゼン−１，２−ジオールの結晶形 |
| FI2291080T5 (fi) | 2008-05-14 | 2023-11-06 | The Scripps Research Institute | Uusia sfingosiinifosfaattireseptorimodulaattoreita |
| US8017555B2 (en) | 2009-02-10 | 2011-09-13 | Divergence, Inc. | Compositions and methods for controlling nematodes |
| EP2413913B1 (en) * | 2009-04-01 | 2022-05-18 | Bial-Portela & CA, S.A. | Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same |
| KR20120027197A (ko) | 2009-04-01 | 2012-03-21 | 바이알 - 포르텔라 앤드 씨에이 에스에이 | 니트로카테콜 유도체를 포함하는 제약 제제 및 그의 제조 방법 |
| EP2454255B1 (en) | 2009-07-16 | 2013-11-06 | Actelion Pharmaceuticals Ltd. | Pyridin-4-yl derivatives as s1p1/edg1 agonists |
| JP5859570B2 (ja) | 2011-01-19 | 2016-02-10 | アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | ２−メトキシ−ピリジン−４−イル誘導体 |
| US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
| WO2013089573A1 (en) | 2011-12-13 | 2013-06-20 | BIAL - PORTELA & Cª., S.A. | Chemical compound useful as intermediate for preparing a catechol-o-methyltransferase inhibitor |
| UY35327A (es) * | 2013-02-15 | 2014-09-30 | Monsanto Technology Llc | ?4,5-dihidro-1,2,4-oxadiazoles disustituidos en 3,5 y composiciones y métodos para controlar plagas de nematodos?. |
| JP2018500300A (ja) | 2014-11-28 | 2018-01-11 | ノヴィファーマ，エス．アー． | パーキンソン病を遅延させるための医薬 |
| KR20200044155A (ko) | 2015-05-20 | 2020-04-28 | 이도르시아 파마슈티컬스 리미티드 | 화합물 (s)-3-｛4-[5-(2-시클로펜틸-6-메톡시-피리딘-4-일)-[1,2,4]옥사디아졸-3-일]-2-에틸-6-메틸-페녹시｝-프로판-1,2-디올의 결정형 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL120029C (cs) * | 1959-09-29 | |||
| US3227725A (en) * | 1962-04-17 | 1966-01-04 | Union Carbide Corp | Certain 3,5-disubstituted 1,2,4-oxadiazole compounds |
-
1969
- 1969-04-08 US US815520A patent/US3647809A/en not_active Expired - Lifetime
- 1969-04-08 IL IL31990A patent/IL31990A/xx unknown
- 1969-04-14 GB GB09047/69A patent/GB1271302A/en not_active Expired
- 1969-04-18 AT AT375469A patent/AT292727B/de not_active IP Right Cessation
- 1969-04-18 AT AT815670A patent/AT292728B/de not_active IP Right Cessation
- 1969-04-19 DE DE19691920037 patent/DE1920037A1/de active Pending
- 1969-04-24 CH CH1476972A patent/CH542232A/de not_active IP Right Cessation
- 1969-04-24 CH CH627569A patent/CH540925A/de not_active IP Right Cessation
- 1969-04-24 FR FR696912994A patent/FR2007529B1/fr not_active Expired
- 1969-04-25 CA CA049,755A patent/CA954858A/en not_active Expired
- 1969-04-25 NL NL6906401A patent/NL6906401A/xx unknown
- 1969-04-25 JP JP44032259A patent/JPS4824394B1/ja active Pending
- 1969-04-25 SE SE05909/69A patent/SE368576B/xx unknown
- 1969-04-25 BE BE732131D patent/BE732131A/xx unknown
- 1969-04-25 BR BR208381/69A patent/BR6908381D0/pt unknown
- 1969-04-25 NO NO1733/69A patent/NO124253B/no unknown
- 1969-04-25 PL PL1969133199A patent/PL79435B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1271302A (en) | 1972-04-19 |
| FR2007529A1 (cs) | 1970-01-09 |
| NO124253B (cs) | 1972-03-27 |
| IL31990A0 (en) | 1969-06-25 |
| BR6908381D0 (pt) | 1973-02-08 |
| NL6906401A (cs) | 1969-10-28 |
| JPS4824394B1 (cs) | 1973-07-20 |
| AT292728B (de) | 1971-09-10 |
| CH542232A (de) | 1973-11-15 |
| DE1920037A1 (de) | 1970-11-12 |
| BE732131A (cs) | 1969-10-01 |
| CH540925A (de) | 1973-08-31 |
| CA954858A (en) | 1974-09-17 |
| US3647809A (en) | 1972-03-07 |
| SE368576B (cs) | 1974-07-08 |
| PL79435B1 (en) | 1975-06-30 |
| AT292727B (de) | 1971-09-10 |
| FR2007529B1 (cs) | 1973-03-16 |
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