CA3234375A1 - Pyrazoloquinoline kras inhibitors - Google Patents

Pyrazoloquinoline kras inhibitors Download PDF

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Publication number
CA3234375A1
CA3234375A1 CA3234375A CA3234375A CA3234375A1 CA 3234375 A1 CA3234375 A1 CA 3234375A1 CA 3234375 A CA3234375 A CA 3234375A CA 3234375 A CA3234375 A CA 3234375A CA 3234375 A1 CA3234375 A1 CA 3234375A1
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CA
Canada
Prior art keywords
compound
pharmaceutically acceptable
fluoro
acceptable salt
quinolin
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Pending
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CA3234375A
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English (en)
French (fr)
Inventor
Wenyu Zhu
Xiaozhao Wang
Wenqing Yao
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Incyte Corp
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Incyte Corp
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Publication of CA3234375A1 publication Critical patent/CA3234375A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3234375A 2021-10-01 2022-09-30 Pyrazoloquinoline kras inhibitors Pending CA3234375A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163261982P 2021-10-01 2021-10-01
US63/261,982 2021-10-01
PCT/US2022/077350 WO2023056421A1 (en) 2021-10-01 2022-09-30 Pyrazoloquinoline kras inhibitors

Publications (1)

Publication Number Publication Date
CA3234375A1 true CA3234375A1 (en) 2023-04-06

Family

ID=83902891

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3234375A Pending CA3234375A1 (en) 2021-10-01 2022-09-30 Pyrazoloquinoline kras inhibitors

Country Status (7)

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US (2) US12030884B2 (https=)
EP (1) EP4408536A1 (https=)
JP (1) JP2024537824A (https=)
AR (1) AR127235A1 (https=)
CA (1) CA3234375A1 (https=)
TW (1) TW202330521A (https=)
WO (1) WO2023056421A1 (https=)

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US20230143938A1 (en) 2023-05-11
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