CA3202461A1 - Dicarboxylic acid esters for inducing an analgesic effect - Google Patents

Dicarboxylic acid esters for inducing an analgesic effect

Info

Publication number
CA3202461A1
CA3202461A1 CA3202461A CA3202461A CA3202461A1 CA 3202461 A1 CA3202461 A1 CA 3202461A1 CA 3202461 A CA3202461 A CA 3202461A CA 3202461 A CA3202461 A CA 3202461A CA 3202461 A1 CA3202461 A1 CA 3202461A1
Authority
CA
Canada
Prior art keywords
pain
subject
acid ester
dicarboxylic acid
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3202461A
Other languages
English (en)
French (fr)
Inventor
Robert T. Streeper
Elzbieta Izbicka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New Frontier Labs LLC
Original Assignee
New Frontier Labs LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New Frontier Labs LLC filed Critical New Frontier Labs LLC
Publication of CA3202461A1 publication Critical patent/CA3202461A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3202461A 2020-12-16 2021-12-16 Dicarboxylic acid esters for inducing an analgesic effect Pending CA3202461A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063126387P 2020-12-16 2020-12-16
US63/126,387 2020-12-16
PCT/IB2021/061872 WO2022130288A1 (en) 2020-12-16 2021-12-16 Dicarboxylic acid esters for inducing an analgesic effect

Publications (1)

Publication Number Publication Date
CA3202461A1 true CA3202461A1 (en) 2022-06-23

Family

ID=81942874

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3202461A Pending CA3202461A1 (en) 2020-12-16 2021-12-16 Dicarboxylic acid esters for inducing an analgesic effect

Country Status (12)

Country Link
US (1) US11911358B2 (enExample)
EP (1) EP4262779A4 (enExample)
JP (1) JP7837335B2 (enExample)
KR (1) KR20230131182A (enExample)
CN (1) CN116829141A (enExample)
AU (1) AU2021400215A1 (enExample)
CA (1) CA3202461A1 (enExample)
CL (1) CL2023001737A1 (enExample)
CO (1) CO2023007903A2 (enExample)
IL (1) IL303751A (enExample)
MX (1) MX2023006728A (enExample)
WO (1) WO2022130288A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022022437A2 (pt) 2020-05-07 2023-01-03 Adorx Therapeutics Ltd Antagonistas do receptor a2a de adenosina
US20260048034A1 (en) 2024-08-15 2026-02-19 New Frontier Labs, Llc Compositions and methods for enhancing the efficacy of dicarboxylic acid esters, and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS539788A (en) * 1976-07-14 1978-01-28 Syntex Inc 55aloyll1*22dihydroo3hh pyroro *1*22a* pyroll11 carboxylic acid derivative
JPH07116026B2 (ja) * 1987-07-07 1995-12-13 株式会社資生堂 ジクロフェナックナトリウム含有乳化外用剤
JP2523428B2 (ja) * 1992-12-04 1996-08-07 エスエス製薬株式会社 消炎鎮痛ゲル製剤
US9265725B2 (en) * 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
JP2004300113A (ja) * 2003-04-01 2004-10-28 Nichiban Co Ltd 消炎鎮痛貼付剤
WO2006074379A2 (en) * 2005-01-07 2006-07-13 Azaya Therapeutics, Inc. Methods and compositions involving esters of azelaic acid and other dicarboxylic acids
US8822509B2 (en) * 2006-12-29 2014-09-02 The University Of Queensland Pain-relieving compositions and uses therefor
EP2219633A2 (en) * 2007-11-23 2010-08-25 Nectid, Inc. Tapentadol compositions
US20090326069A1 (en) * 2008-06-30 2009-12-31 Bltn, Llc Azelaic acid ester compositions and methods for diagnosing and treating tissue conditions using azelaic acid ester compositions and proteinaceous biomarkers
BRPI0901758A2 (pt) * 2009-05-28 2011-01-25 Cristalia Prod Quimicos Farm uso de telocinobufagina como analgésico no tratamento das dores aguda e crÈnica; composição farmacêutica contendo telocinobufagina e uso da mesma
US20120251525A1 (en) * 2009-06-30 2012-10-04 Streeper Robert T Method of utilizing azelaic acid esters to modulate communications mediated by biological molecules
EP3445354B8 (en) * 2016-04-20 2022-07-06 New Frontier Labs, LLC Azelaic acid esters in the treatment of insulin resistance
US20220023423A1 (en) * 2018-12-19 2022-01-27 Medrx Co., Ltd. Anti-Inflammatory Analgesic External Preparation
CN111544381B (zh) * 2020-05-12 2021-07-16 普霖贝利生物医药研发(上海)有限公司 一种包含壬二酸的皮肤局部给药组合物

Also Published As

Publication number Publication date
AU2021400215A9 (en) 2025-03-20
CN116829141A (zh) 2023-09-29
MX2023006728A (es) 2023-06-19
WO2022130288A1 (en) 2022-06-23
KR20230131182A (ko) 2023-09-12
EP4262779A4 (en) 2024-11-13
US11911358B2 (en) 2024-02-27
AU2021400215A1 (en) 2023-07-06
US20220184023A1 (en) 2022-06-16
IL303751A (en) 2023-08-01
CO2023007903A2 (es) 2023-06-30
CL2023001737A1 (es) 2024-01-19
JP2023553642A (ja) 2023-12-25
EP4262779A1 (en) 2023-10-25
JP7837335B2 (ja) 2026-03-30

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