CA3177086A1 - Modified membrane type serine protease 1 (mtsp-1) polypeptides and methods of use - Google Patents

Modified membrane type serine protease 1 (mtsp-1) polypeptides and methods of use

Info

Publication number
CA3177086A1
CA3177086A1 CA3177086A CA3177086A CA3177086A1 CA 3177086 A1 CA3177086 A1 CA 3177086A1 CA 3177086 A CA3177086 A CA 3177086A CA 3177086 A CA3177086 A CA 3177086A CA 3177086 A1 CA3177086 A1 CA 3177086A1
Authority
CA
Canada
Prior art keywords
ins97av
d6obt
y60gw
f60es
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3177086A
Other languages
English (en)
French (fr)
Inventor
Edwin L. Madison
Vanessa Soros
Mikhail Popkov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vertex Pharmaceuticals Inc
Original Assignee
Catalyst Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalyst Biosciences Inc filed Critical Catalyst Biosciences Inc
Publication of CA3177086A1 publication Critical patent/CA3177086A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21109—Matriptase (3.4.21.109)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Photolithography (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Medicinal Preparation (AREA)
CA3177086A 2017-06-22 2018-06-21 Modified membrane type serine protease 1 (mtsp-1) polypeptides and methods of use Pending CA3177086A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762523735P 2017-06-22 2017-06-22
US62/523,735 2017-06-22
US201862664051P 2018-04-27 2018-04-27
US62/664,051 2018-04-27
CA3067851A CA3067851C (en) 2017-06-22 2018-06-21 Modified membrane type serine protease 1 (mtsp-1) polypeptides and methods of use

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA3067851A Division CA3067851C (en) 2017-06-22 2018-06-21 Modified membrane type serine protease 1 (mtsp-1) polypeptides and methods of use

Publications (1)

Publication Number Publication Date
CA3177086A1 true CA3177086A1 (en) 2018-12-27

Family

ID=63015005

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3177086A Pending CA3177086A1 (en) 2017-06-22 2018-06-21 Modified membrane type serine protease 1 (mtsp-1) polypeptides and methods of use
CA3067851A Active CA3067851C (en) 2017-06-22 2018-06-21 Modified membrane type serine protease 1 (mtsp-1) polypeptides and methods of use

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3067851A Active CA3067851C (en) 2017-06-22 2018-06-21 Modified membrane type serine protease 1 (mtsp-1) polypeptides and methods of use

Country Status (19)

Country Link
US (5) US10781435B2 (https=)
EP (1) EP3641801A1 (https=)
JP (3) JP7091373B2 (https=)
KR (1) KR102675270B1 (https=)
CN (1) CN111107870A (https=)
AU (2) AU2018290281B2 (https=)
BR (1) BR112019027583A2 (https=)
CA (2) CA3177086A1 (https=)
CL (3) CL2019003813A1 (https=)
CO (1) CO2020000584A2 (https=)
IL (2) IL308949B2 (https=)
JO (1) JOP20190288A1 (https=)
MX (1) MX2019015402A (https=)
MY (1) MY202652A (https=)
PE (1) PE20200697A1 (https=)
PH (1) PH12019502838A1 (https=)
SG (3) SG10202110492YA (https=)
WO (1) WO2018237201A1 (https=)
ZA (1) ZA202000332B (https=)

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US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
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WO2019118921A1 (en) 2017-12-14 2019-06-20 Flodesign Sonics, Inc. Acoustic transducer drive and controller
BR112021026852A2 (pt) * 2019-07-03 2022-02-22 Palleon Pharmaceuticals Inc Sialidases recombinantes e métodos de uso das mesmas
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CN113456527B (zh) * 2021-07-30 2023-04-07 北京清大赛尔生物科技有限公司 一种nadh微胶囊制剂及其制备方法和应用
KR20240145409A (ko) * 2023-03-24 2024-10-07 카오티에스 주식회사 신규한 그랜자임 융합단백질 및 이의 용도
CN119570766B (zh) * 2025-02-08 2025-05-16 上海锴泰生物科技有限公司 一种胶原蛋白酶突变体、基因片段、重组质粒、重组表达体系、胶原蛋白肽，及其制备方法和用途
CN121538228B (zh) * 2026-01-21 2026-04-10 山东寿光巨能金玉米开发有限公司 一种NCgl0081基因突变体及其在制备L-赖氨酸中的应用

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