CA3106048A1 - Antibody molecules that bind cd137 and ox40 - Google Patents
Antibody molecules that bind cd137 and ox40 Download PDFInfo
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- CA3106048A1 CA3106048A1 CA3106048A CA3106048A CA3106048A1 CA 3106048 A1 CA3106048 A1 CA 3106048A1 CA 3106048 A CA3106048 A CA 3106048A CA 3106048 A CA3106048 A CA 3106048A CA 3106048 A1 CA3106048 A1 CA 3106048A1
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| PCT/EP2019/068796 WO2020011966A1 (en) | 2018-07-12 | 2019-07-12 | Antibody molecules that bind cd137 and ox40 |
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| GB201811415D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Anti-Mesothelin Anti bodies |
| GB201811404D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Anti-CD137 Antibodies |
| GB201811410D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | OX40 Binding molecules |
| TWI861005B (zh) | 2018-07-12 | 2024-11-11 | 英商英沃克斯製藥有限公司 | 結合pd-l1及cd137的抗體分子 |
| GB201811450D0 (en) | 2018-07-12 | 2018-08-29 | F Star Delta Ltd | Mesothelin and CD137 binding molecules |
| GB201811403D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Antibody molecules |
| GB201811408D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | CD137 Binding Molecules |
| WO2020229626A1 (en) | 2019-05-14 | 2020-11-19 | F-Star Delta Limited | Dosage regimes for the administration of a lag-3/pd-l1 bispecific antibody |
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| AU2019301206B2 (en) | 2025-10-30 |
| JP7701964B2 (ja) | 2025-07-02 |
| US20220048996A1 (en) | 2022-02-17 |
| IL280002B2 (en) | 2025-05-01 |
| JP2021524267A (ja) | 2021-09-13 |
| TWI847989B (zh) | 2024-07-11 |
| WO2020011966A1 (en) | 2020-01-16 |
| EP3820898B1 (en) | 2025-09-03 |
| IL280002B1 (en) | 2025-01-01 |
| ES3044118T3 (en) | 2025-11-26 |
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| CN112424229A (zh) | 2021-02-26 |
| IL280002A (en) | 2021-03-01 |
| CN112424229B (zh) | 2024-07-30 |
| US12252537B2 (en) | 2025-03-18 |
| JP7397055B2 (ja) | 2023-12-12 |
| AU2019301206A1 (en) | 2021-03-04 |
| EP3820898A1 (en) | 2021-05-19 |
| SG11202100172XA (en) | 2021-02-25 |
| KR20210031479A (ko) | 2021-03-19 |
| MX2021000399A (es) | 2021-05-27 |
| ZA202100718B (en) | 2025-07-30 |
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