CA3052266A1 - Methods and compositions for matrix preparation - Google Patents

Methods and compositions for matrix preparation Download PDF

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Publication number
CA3052266A1
CA3052266A1 CA3052266A CA3052266A CA3052266A1 CA 3052266 A1 CA3052266 A1 CA 3052266A1 CA 3052266 A CA3052266 A CA 3052266A CA 3052266 A CA3052266 A CA 3052266A CA 3052266 A1 CA3052266 A1 CA 3052266A1
Authority
CA
Canada
Prior art keywords
collagen
matrix
clauses
buffer solution
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3052266A
Other languages
English (en)
French (fr)
Inventor
Sherry L. Voytik-Harbin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Geniphys Inc
Original Assignee
Geniphys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geniphys Inc filed Critical Geniphys Inc
Publication of CA3052266A1 publication Critical patent/CA3052266A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/10—Ultraviolet [UV] radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
CA3052266A 2017-01-31 2018-01-31 Methods and compositions for matrix preparation Pending CA3052266A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762452564P 2017-01-31 2017-01-31
US62/452,564 2017-01-31
PCT/US2018/016069 WO2018144496A1 (en) 2017-01-31 2018-01-31 Methods and compositions for matrix preparation

Publications (1)

Publication Number Publication Date
CA3052266A1 true CA3052266A1 (en) 2018-08-09

Family

ID=63041072

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3052266A Pending CA3052266A1 (en) 2017-01-31 2018-01-31 Methods and compositions for matrix preparation

Country Status (7)

Country Link
US (1) US12280176B2 (enExample)
EP (1) EP3576775B1 (enExample)
JP (1) JP7242553B2 (enExample)
CN (1) CN110446500B (enExample)
CA (1) CA3052266A1 (enExample)
ES (1) ES3040675T3 (enExample)
WO (1) WO2018144496A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11808760B1 (en) * 2019-02-14 2023-11-07 Curi Bio, Inc. System and methods for in vitro structural toxicity testing

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
EP3185922B1 (en) 2014-08-27 2025-04-02 Purdue Research Foundation Collagen-based therapeutic delivery systems
WO2016172365A1 (en) 2015-04-21 2016-10-27 Purdue Research Foundation Office Of Technology Commercialization Cell-collagen-silica composites and methods of making and using the same
US12280176B2 (en) 2017-01-31 2025-04-22 Geniphys, Inc. Methods and compositions for matrix preparation
WO2018200750A1 (en) 2017-04-25 2018-11-01 Purdue Research Foundation 3-dimensional (3d) tissue-engineered muscle for tissue restoration
JP7881181B2 (ja) * 2020-01-27 2026-06-29 ジェニフィス,インコーポレイテッド 組織を回復および再生させるための生物学的充填剤
IL318632A (en) * 2022-08-19 2025-03-01 Sylvan Inc Electron beam irradiation for media sterilization prior to inoculation with fungi and related methods
CN116999619B (zh) * 2023-08-03 2024-03-19 浙江崇山生物制品有限公司 一种软骨用胶原凝胶及其制备方法

Family Cites Families (169)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949073A (en) 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
US4233360A (en) 1975-10-22 1980-11-11 Collagen Corporation Non-antigenic collagen and articles of manufacture
US4439521A (en) 1981-10-21 1984-03-27 Ontario Cancer Institute Method for producing self-reproducing mammalian pancreatic islet-like structures
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4544516A (en) 1982-07-28 1985-10-01 Battelle Development Corporation Collagen orientation
US4801299A (en) 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
IL74715A0 (en) 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same
US4789663A (en) 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
US4743552A (en) 1984-09-26 1988-05-10 Sloan-Kettering Institute For Cancer Research Method for growth in tissue culture of normal colonic epithelial cells and method for determination of preneoplastic color cells
US4600533A (en) 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
US4829000A (en) 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US5266480A (en) 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5032508A (en) 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5863531A (en) 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
GB8618374D0 (en) 1986-07-28 1986-09-03 Hsc Res Dev Corp Biological vascular prostheses
JPH0774239B2 (ja) 1986-09-04 1995-08-09 新田ゼラチン株式会社 細胞培養用高ゲル強度酸可溶性コラーゲンの製法
US5604106A (en) 1987-06-05 1997-02-18 Us Commerce Method for detecting carcinoma
US5067961A (en) 1988-02-18 1991-11-26 Autogenesis Technologies, Inc. Non-biodegradable two phase corneal implant and method for preparing same
JPH0728730B2 (ja) 1988-03-27 1995-04-05 新技術事業団 擬膵島および拡散チャンバー型人工膵臟
US4956178A (en) 1988-07-11 1990-09-11 Purdue Research Foundation Tissue graft composition
US4902508A (en) 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US4912057A (en) 1989-06-13 1990-03-27 Cancer Diagnostics, Inc. Cell chamber for chemotaxis assay
US5336616A (en) 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US5163955A (en) 1991-01-24 1992-11-17 Autogenics Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
WO1992015676A1 (en) 1991-03-08 1992-09-17 The Salk Institute For Biological Studies Somatic cell gene therapy
DE69232535T4 (de) 1991-06-24 2003-09-11 Hcell Technology, Inc. In langzeitkultur gehaltene hormon-absondernde pankreatische zellen
FR2678624A1 (fr) 1991-07-04 1993-01-08 Coletica Utilisation de la peau non pigmentee de poisson, en particulier de poisson plat comme nouvelle source industrielle de collagene, procede d'extraction, collagene et biomateriau ainsi obtenus.
US5281422A (en) 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5204382A (en) 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
US5428022A (en) 1992-07-29 1995-06-27 Collagen Corporation Composition of low type III content human placental collagen
US5478739A (en) 1992-10-23 1995-12-26 Advanced Tissue Sciences, Inc. Three-dimensional stromal cell and tissue culture system
US5275826A (en) 1992-11-13 1994-01-04 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
US5352463A (en) 1992-11-13 1994-10-04 Badylak Steven F Tissue graft for surgical reconstruction of a collagenous meniscus and method therefor
US5641518A (en) 1992-11-13 1997-06-24 Purdue Research Foundation Method of repairing bone tissue
US5510263A (en) 1993-04-05 1996-04-23 Desmos, Inc. Growth of pancreatic islet-like cell clusters
US5460962A (en) 1994-01-04 1995-10-24 Organogenesis Inc. Peracetic acid sterilization of collagen or collagenous tissue
JPH0789564B2 (ja) 1994-04-12 1995-09-27 株式会社東芝 半導体装置の製造方法
US6475232B1 (en) 1996-12-10 2002-11-05 Purdue Research Foundation Stent with reduced thrombogenicity
US5709934A (en) 1994-11-22 1998-01-20 Tissue Engineering, Inc. Bipolymer foams having extracellular matrix particulates
US5695998A (en) 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
US6485723B1 (en) 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US5916790A (en) 1995-03-03 1999-06-29 Metabolex, Inc. Encapsulation compositions, and methods
US5711969A (en) 1995-04-07 1998-01-27 Purdue Research Foundation Large area submucosal tissue graft constructs
US5554389A (en) 1995-04-07 1996-09-10 Purdue Research Foundation Urinary bladder submucosa derived tissue graft
US5776193A (en) 1995-10-16 1998-07-07 Orquest, Inc. Bone grafting matrix
AU736255B2 (en) 1995-10-25 2001-07-26 Shire Human Genetic Therapies, Inc. Hybrid matrix implants and explants
US6419920B1 (en) 1995-10-25 2002-07-16 Trans Karyotic Therapies, Inc. Hybrid matrix implants and explants
WO1997017038A1 (en) 1995-11-09 1997-05-15 University Of Massachusetts Tissue re-surfacing with hydrogel-cell compositions
JP2000508922A (ja) 1996-04-26 2000-07-18 ケース ウエスターン リザーブ ユニバーシティ 間葉幹細胞を用いる皮膚再生
US6171344B1 (en) 1996-08-16 2001-01-09 Children's Medical Center Corporation Bladder submucosa seeded with cells for tissue reconstruction
EP0927052B1 (en) 1996-08-16 2003-04-16 The Children's Medical Center Corporation Bladder submucosa seeded with cells for tissue reconstruction
US6666892B2 (en) 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
KR100650295B1 (ko) 1996-08-23 2006-11-28 쿠크 바이오텍, 인코포레이티드 조직이식기관, 조직이식물 및 조직이식방법
DK0925067T3 (da) 1996-09-16 2004-05-03 Purdue Research Foundation Graft fra submucosavæv til reparation af neurologisk væv
AU728848B2 (en) 1996-12-10 2001-01-18 Purdue Research Foundation Tubular submucosal graft constructs
WO1998025964A1 (en) 1996-12-10 1998-06-18 Purdue Research Foundation Submucosa extracts
ES2263185T3 (es) 1996-12-10 2006-12-01 Purdue Research Foundation Biomaterial derivado de tejido hepatico de vertebrados.
EP0946186B1 (en) 1996-12-10 2003-03-26 Purdue Research Foundation Stomach submucosa derived tissue graft
WO1998052637A1 (en) 1997-05-23 1998-11-26 Biosense, Inc. Catheter with oblique lumen
EP1000089A4 (en) 1997-07-28 2001-08-29 Fibrogen Inc ADHESIVE COMPOSITIONS BASED ON TYPE I AND TYPE III COLLAGEN
US6248587B1 (en) 1997-11-26 2001-06-19 University Of Southern Cailfornia Method for promoting mesenchymal stem and lineage-specific cell proliferation
WO1999043786A2 (en) 1998-02-27 1999-09-02 Purdue Research Foundation Submucosa gel compositions
DE19812713A1 (de) 1998-03-24 1999-09-30 Merck Patent Gmbh Verfahren zur Herstellung von mineralisierten Kollagenfibrillen und deren Verwendung als Knochenersatzwerkstoff
JP2002525043A (ja) 1998-09-11 2002-08-13 パーデュー・リサーチ・ファウンデーション 改良粘膜下組織グラフト構成物
BR9915476A (pt) 1998-11-19 2002-01-02 Organogenesis Inc Construtos de tecidos feitos por bioengenharia e métodos para a sua produção e utilização
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
IL144703A (en) 1999-02-10 2010-04-15 Curis Inc Use of peptide yy for the preparation of a pharmaceutical composition for enhancing pancreatic cell differentiation
US7615373B2 (en) 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US6592623B1 (en) 1999-08-31 2003-07-15 Virginia Commonwealth University Intellectual Property Foundation Engineered muscle
US20050153442A1 (en) 1999-03-10 2005-07-14 Adam Katz Adipose-derived stem cells and lattices
WO2000062833A1 (en) 1999-04-15 2000-10-26 The Research Foundation Of State University Of New York Cellular matrix system and use thereof
CA2378618C (en) 1999-08-06 2009-10-06 Cook Biotech Incorporated Tubular graft construct
US6592794B1 (en) 1999-09-28 2003-07-15 Organogenesis Inc. Process of making bioengineered collagen fibrils
EP1216296B1 (en) 1999-09-28 2009-04-15 Organogenesis Inc. Bioengineered collagen fibrils
US6482240B1 (en) 1999-12-07 2002-11-19 Ed. Geistlich Soehne Ag Fur Chemische Industrie Method of making a collagen membrane from porcine skin
ATE262358T1 (de) 1999-12-22 2004-04-15 Acell Inc Zusammensetzung zur gewebsregeneration
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
US6479064B1 (en) 1999-12-29 2002-11-12 Children's Medical Center Corporation Culturing different cell populations on a decellularized natural biostructure for organ reconstruction
US20020039788A1 (en) 2000-02-29 2002-04-04 Isseroff Roslyn R. Corneal epithelial graft composites
AU5159901A (en) 2000-04-14 2001-10-30 Univ Pittsburgh Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof
US6893812B2 (en) 2000-05-30 2005-05-17 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Three-dimensional ex vivo angiogenesis system
ATE308610T1 (de) 2000-05-31 2005-11-15 Fraunhofer Ges Forschung Dreidimensionales hautmodell
DE20019809U1 (de) 2000-05-31 2001-07-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 80636 München Knorpelersatz und Biomatrix zur Kultivierung von Zellen
CZ301649B6 (cs) 2000-06-28 2010-05-12 Ed. Geistlich Soehne Ag Fur Chemische Industrie Incorporated Under The Laws Of Switzerland Trubice pro regeneraci nervu a zpusob jejich výroby
DE10032610C2 (de) 2000-07-07 2003-05-15 Fischer W Mueller Blasformtech Verfahren zum Herstellen von Kunststoff-Blasformartikeln
HUP0300810A2 (hu) 2000-07-20 2003-08-28 M.G.V.S. Ltd. Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása
CA2419817C (en) 2000-08-16 2014-11-18 Duke University Decellularized tissue engineered constructs and tissues
EP1315797A2 (en) 2000-09-06 2003-06-04 Universit Laval In vitro human angiogenesis model
US20020076816A1 (en) 2000-12-04 2002-06-20 Jianwu Dai Stem cells and signals developed for use in tissue and organ repair and replacement
US6586493B1 (en) 2001-03-07 2003-07-01 Arizona Board Of Regents Arizona State University Polysaccharide-based hydrogels and pre-gel blends for the same
US7029689B2 (en) 2001-05-10 2006-04-18 Georgia Tech Research Corporation Tubular construct for implantation
CA2388723C (en) 2001-06-06 2012-10-23 Becton, Dickinson & Company Method of providing a substrate with a ready-to-use, uniformly distributed extracellular matrix
US20030078653A1 (en) 2001-06-15 2003-04-24 Ivan Vesely Tissue engineered mitral valve chordae and methods of making and using same
EP1270672B1 (en) 2001-06-28 2007-11-14 PV Industries B.V. Process for recovering native collagen
WO2003002165A1 (en) 2001-06-28 2003-01-09 Cook Biotech Incorporated Graft prosthesis devices containing renal capsule collagen
AU2002323526A1 (en) 2001-08-31 2003-03-18 Pacgen Cellco Llc Use of recipient endothelial cells for enhanced vascularization of tissue and tissue-engineered construct transplants
DE20115753U1 (de) 2001-09-14 2002-01-10 Institut für Agrar- und Stadtökologische Projekte an der Humboldt-Universität zu Berlin, 10115 Berlin Lösliche Kollagene
US7919121B2 (en) 2002-01-11 2011-04-05 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
US8394371B2 (en) 2002-02-11 2013-03-12 Neocutis Sa Compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same
US20060014284A1 (en) 2002-03-21 2006-01-19 Thomas Graeve Biomatrix and method for producting the same
CA2482351A1 (en) 2002-04-12 2003-10-23 Yale University Vascularized human skin equivalent
EP1503652A4 (en) 2002-05-02 2006-02-08 Purdue Research Foundation HYBRID GRAFTS WITH IMPROVED VASCULARIZATION
NZ536564A (en) 2002-05-02 2008-05-30 Purdue Research Foundation Vascularization enhanced graft constructs which comprise a matrix composition consisting of liver basement membrane
EP1585426A4 (en) 2002-05-02 2006-09-20 Cook Biotech Inc WITH CELLS VACCINATED EXTRACELLULAR MATRIX TRANSPLANTS
CA2483683C (en) 2002-05-02 2013-07-02 Purdue Research Foundation Vascularization enhanced graft constructs
AUPS242702A0 (en) 2002-05-21 2002-06-13 Colltech Australia Limited Improved method for the extraction and purification of collagen
US20060258560A1 (en) 2002-09-30 2006-11-16 Chunlin Yang Dry tissue sealant compositions
US20040126405A1 (en) 2002-12-30 2004-07-01 Scimed Life Systems, Inc. Engineered scaffolds for promoting growth of cells
JP2006519086A (ja) 2003-02-28 2006-08-24 ファイブローゲン、インコーポレーテッド コラーゲン組成物および生体材料
CA2528134C (en) 2003-06-04 2015-05-12 University Of South Carolina Tissue scaffold having aligned fibrils, apparatus and method for producing the same, and artificial tissue and methods of use thereof
US20050014181A1 (en) 2003-06-18 2005-01-20 Galis Zorina S. Methods and compositions for the assessment of polymer assembly
US8741352B2 (en) 2003-08-25 2014-06-03 Cook Biotech Incorporated Graft materials containing ECM components, and methods for their manufacture
US8043614B2 (en) 2004-03-09 2011-10-25 Ahlfors Jan-Eric W Autogenic living scaffolds and living tissue matrices: methods and uses thereof
US20050266556A1 (en) 2004-02-09 2005-12-01 Yoder Mervin C Isolation, expansion and use of clonogenic endothelial progenitor cells
US8337545B2 (en) 2004-02-09 2012-12-25 Cook Medical Technologies Llc Woven implantable device
US8241905B2 (en) 2004-02-24 2012-08-14 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
WO2005085422A1 (en) 2004-02-27 2005-09-15 Michigan State University Adult stem cells and uses thereof
GB0415080D0 (en) 2004-07-05 2004-08-04 Ucl Biomedica Plc Methods for preparing tissue equivalent implants and products thereof
WO2006030442A2 (en) 2004-09-16 2006-03-23 Gamida-Cell Ltd. Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells
JP2008517660A (ja) 2004-10-22 2008-05-29 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ 生物剤を送達する中空かつ多孔質の整形外科用または歯科用のインプラント
US20060165667A1 (en) 2004-12-03 2006-07-27 Case Western Reserve University Novel methods, compositions and devices for inducing neovascularization
US20060134072A1 (en) 2004-12-22 2006-06-22 Pedrozo Hugo A Self-assembling protein matrix prepared from natural extracellular matrices
WO2006099332A2 (en) 2005-03-11 2006-09-21 Wake Forest University Health Sciences Production of tissue engineered digits and limbs
EP1869169A4 (en) 2005-03-29 2015-11-04 Univ California REGULATION OF THE DESTINATION OF STEM CELLS WITH TUNABLE NETS
WO2006125025A2 (en) 2005-05-16 2006-11-23 Purdue Research Foundation Engineered extracellular matrices control stem cell behavior
GB2441098B (en) 2005-05-16 2010-05-26 Purdue Research Foundation Engineered extracellular matrices
US20100068804A1 (en) 2005-09-01 2010-03-18 Duke University Methods of stimulating expansion of hematopoietic stem cells
GB0524048D0 (en) 2005-11-25 2006-01-04 Ucl Biomedica Plc Bio-artificial materials with tuneable properties
US20070190646A1 (en) 2006-02-10 2007-08-16 The Trustees Of The University Of Pennsylvania Regulating stem cell differentiation by controlling matrix elasticity
US20070269476A1 (en) 2006-05-16 2007-11-22 Voytik-Harbin Sherry L Engineered extracellular matrices control stem cell behavior
DE112007001197T5 (de) 2006-05-16 2009-04-16 Purdue Research Foundation, West Lafayette Dreidimensionale gereinigte Kollagenmatrices
US20080026032A1 (en) 2006-07-27 2008-01-31 Zubery Yuval Composite implants for promoting bone regeneration and augmentation and methods for their preparation and use
CA2663722C (en) 2006-09-21 2014-12-09 Purdue Research Foundation Collagen preparation and method of isolation
AU2007318210B2 (en) 2006-10-06 2014-02-20 Celularity Inc. Native (telopeptide) placental collagen compositions
WO2008056368A2 (en) 2006-11-09 2008-05-15 Gamida-Cell Ltd. Use of ex-vivo cultured hematopoietic cells for treatment of peripheral vascular diseases
WO2008101100A2 (en) 2007-02-14 2008-08-21 Indiana University Research And Technology Corporation Composition for stimulating formation of vascular structures
US20100272697A1 (en) 2007-04-10 2010-10-28 Ali Naji Pancreatic islet cells composition and methods
EP2148887B1 (en) 2007-04-19 2014-04-30 Fibralign Corporation Oriented collagen-based materials, films and methods of making same
WO2008154623A2 (en) 2007-06-12 2008-12-18 Musculoskeletal Transplant Foundation Process for sterilizing acellular soft tissue with irradiation
GB0713079D0 (en) 2007-07-05 2007-08-15 Ucl Business Plc biomaterial scaffolds with defined stiffness
WO2009069123A2 (en) 2007-11-26 2009-06-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions comprising fibrous polypeptides and polysaccharides
AU2008335152B2 (en) 2007-12-10 2013-09-12 Indiana University Research And Technology Corporation Collagen-based matrices with stem cells
WO2009136173A2 (en) 2008-05-07 2009-11-12 Ucl Business Plc Biomimetic cell scaffolds
WO2010054121A2 (en) 2008-11-07 2010-05-14 Specialized Vascular Technologies, Inc. Extracellular matrix modulating coatings for medical devices
WO2010123928A1 (en) 2009-04-20 2010-10-28 Purdue Research Foundation Collagen-based matrices for vessel density and size regulation
US9744123B2 (en) 2009-06-30 2017-08-29 Kensey Nash Corporation Biphasic implant device providing gradient
GB0912399D0 (en) 2009-07-16 2009-08-26 Ucl Business Plc Polymeric collagen biomaterials
US20120115222A1 (en) 2009-07-16 2012-05-10 Purdue Research Foundation Composition and method for maintenance, differentiation, and proliferation of stem cells
US8652500B2 (en) 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
WO2011014155A1 (en) 2009-07-27 2011-02-03 National Cheng Kung University Preparation of high purity collagen
CA2770490C (en) 2009-08-11 2024-04-16 The Johns Hopkins University Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products
EP2504472A1 (en) 2009-11-24 2012-10-03 Collplant Ltd. Method of generating collagen fibers
US8475824B2 (en) 2010-01-26 2013-07-02 Warsaw Orthopedic, Inc. Resorbable matrix having elongated particles
WO2011154686A1 (en) 2010-06-10 2011-12-15 Ucl Business Plc Apparatus, kits and methods for the production of biomimetic constructs
GB201011476D0 (en) 2010-07-07 2010-08-25 Ucl Business Plc Controlled production of biomaterial
US20120027732A1 (en) 2010-07-27 2012-02-02 Voytik-Harbin Sherry L Thermoreversible collagen
TW201247157A (en) 2011-05-27 2012-12-01 Hon Hai Prec Ind Co Ltd Object searching system and method, sweeper with the system
WO2012167249A2 (en) 2011-06-02 2012-12-06 Indiana University Research And Technology Corporation Materials and methods for controlling vasculogenesis from endothelial colony forming cells
FR2975922B1 (fr) 2011-06-06 2013-05-31 Arkema France Reacteur a plaques avec injection in situ
WO2014028941A2 (en) 2012-08-17 2014-02-20 Allosource Adipose composition systems and methods
US20140193477A1 (en) 2012-10-11 2014-07-10 Emory University Collagen based materials and uses related thereto
EP2951193A4 (en) * 2013-02-01 2017-03-01 Children's Medical Center Corporation Collagen scaffolds
GB201314312D0 (en) 2013-08-09 2013-09-25 Regentec Ltd Composition and delivery system
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
KR20170070008A (ko) 2014-08-15 2017-06-21 더 존스 홉킨스 유니버시티 조직 복원용 복합 재료
EP3185922B1 (en) 2014-08-27 2025-04-02 Purdue Research Foundation Collagen-based therapeutic delivery systems
CA2995599C (en) 2015-09-10 2021-07-27 Symbiocelltech, Llc Neo-islets comprising stem and islet cells and treatment of diabetes mellitus therewith
US12280176B2 (en) 2017-01-31 2025-04-22 Geniphys, Inc. Methods and compositions for matrix preparation
CA3071159A1 (en) * 2017-07-25 2019-01-31 Purdue Research Foundation Collagen encapsulation of insulin-producing cells

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11808760B1 (en) * 2019-02-14 2023-11-07 Curi Bio, Inc. System and methods for in vitro structural toxicity testing

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