CA3022834A1 - Fulvestrant formulations and methods of their use - Google Patents
Fulvestrant formulations and methods of their use Download PDFInfo
- Publication number
- CA3022834A1 CA3022834A1 CA3022834A CA3022834A CA3022834A1 CA 3022834 A1 CA3022834 A1 CA 3022834A1 CA 3022834 A CA3022834 A CA 3022834A CA 3022834 A CA3022834 A CA 3022834A CA 3022834 A1 CA3022834 A1 CA 3022834A1
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- Canada
- Prior art keywords
- microns
- fulvestrant
- suspension
- pharmaceutical composition
- aqueous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- VWUXBMIQPBEWFH-WCCTWKNTSA-N Fulvestrant Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)CC2=C1 VWUXBMIQPBEWFH-WCCTWKNTSA-N 0.000 title claims abstract description 617
- 229960002258 fulvestrant Drugs 0.000 title claims abstract description 539
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662332842P | 2016-05-06 | 2016-05-06 | |
| US62/332,842 | 2016-05-06 | ||
| US201662420555P | 2016-11-10 | 2016-11-10 | |
| US62/420,555 | 2016-11-10 | ||
| PCT/US2017/031376 WO2017193048A1 (en) | 2016-05-06 | 2017-05-05 | Fulvestrant formulations and methods of their use |
Publications (1)
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| CA3022834A1 true CA3022834A1 (en) | 2017-11-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA3022834A Pending CA3022834A1 (en) | 2016-05-06 | 2017-05-05 | Fulvestrant formulations and methods of their use |
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| US (2) | US20190134059A1 (OSRAM) |
| EP (1) | EP3452011A1 (OSRAM) |
| JP (3) | JP2019516789A (OSRAM) |
| KR (1) | KR102438425B1 (OSRAM) |
| CN (1) | CN109310621A (OSRAM) |
| AU (2) | AU2017261321B2 (OSRAM) |
| CA (1) | CA3022834A1 (OSRAM) |
| CO (1) | CO2018013257A2 (OSRAM) |
| IL (2) | IL285928B2 (OSRAM) |
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| UA (1) | UA125514C2 (OSRAM) |
| WO (1) | WO2017193048A1 (OSRAM) |
| ZA (1) | ZA201807031B (OSRAM) |
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| US11590077B2 (en) | 2016-05-06 | 2023-02-28 | Eagle Pharmaceuticals, Inc. | Fulvestrant formulations and methods of their use |
| BR112020009141A2 (pt) | 2017-11-08 | 2020-10-27 | Eagle Pharmaceuticals, Inc. | método para tratar câncer de mama num indivíduo |
| US12377049B2 (en) * | 2019-12-11 | 2025-08-05 | Shanghai Bocimed Pharmaceutical Co., Ltd. | Fulvestrant pharmaceutical composition, preparation method therefor, and application thereof |
| CN113694017B (zh) * | 2020-05-11 | 2024-04-02 | 鲁南制药集团股份有限公司 | 一种氟维司群注射制剂及其制备方法 |
| WO2022100750A1 (zh) * | 2020-11-16 | 2022-05-19 | 北京厚燊维康科技有限责任公司 | 可用于光动力治疗或诊断的制剂 |
| CN120284882A (zh) * | 2020-12-10 | 2025-07-11 | 上海云晟研新生物科技有限公司 | 氟维司群药物组合物、其制备方法及应用 |
| JP2024545690A (ja) * | 2021-12-20 | 2024-12-10 | サムヤン、ホールディングス、コーポレーション | 溶解度が改善されたフルベストラントの医薬組成物及びその製造方法 |
| KR20240105964A (ko) * | 2022-12-29 | 2024-07-08 | 주식회사 삼양홀딩스 | 약동학적 특성이 우수한 풀베스트란트의 약학 조성물 및 그 제조 방법 |
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| WO2006013369A2 (en) | 2004-08-04 | 2006-02-09 | Camurus Ab | Compositions forming non-lamellar dispersions |
| MX2007013914A (es) | 2005-05-09 | 2008-02-22 | Biosphere Medical S A | Composiciones y metodos que usan microesferas y agentes de contraste no ionicos. |
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| US8158152B2 (en) | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
| CN101108168B (zh) * | 2007-08-03 | 2010-12-08 | 西安力邦医药科技有限责任公司 | 一种氟维司群缓释微球的制备方法 |
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| CN102014925B (zh) | 2008-03-07 | 2013-02-06 | 赛多斯有限责任公司 | 氟维司群配制剂 |
| TW201016220A (en) * | 2008-10-31 | 2010-05-01 | Scinopharm Taiwan Ltd | Micronization form of 7α-[9-(4,4,5,5,5-pentafluoropentylsufinyl)nonyl]estra-1,3,5(10)-triene-3,17β-diol and process for the preparation thereof |
| JP2012530704A (ja) | 2009-06-18 | 2012-12-06 | アボット・ラボラトリーズ | 安定なナノ粒子状薬物懸濁液 |
| EP2460539A4 (en) * | 2009-07-31 | 2013-12-04 | Xi An Libang Medical Technology Co Ltd | MEDICAMENT IN THE FORM OF NANO OR MICROBALLS, METHOD FOR THE PRODUCTION THEREOF AND COMPOSITION THEREOF AND USE THEREOF |
| WO2011022861A1 (zh) * | 2009-08-31 | 2011-03-03 | 西安力邦医药科技有限责任公司 | 氟维司群纳米球/微球及其制备方法和用途 |
| WO2012021791A2 (en) | 2010-08-13 | 2012-02-16 | Scidose Llc | Aqueous formulation with improved stability |
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| SG10201706196XA (en) | 2012-06-08 | 2017-08-30 | Hoffmann La Roche | Mutant selectivity and combinations of a phosphoinositide 3 kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer |
| CN104337761B (zh) * | 2013-08-07 | 2019-03-26 | 江苏豪森药业集团有限公司 | 氟维司群药物组合物 |
| JP2016529308A (ja) * | 2013-09-06 | 2016-09-23 | サラー ウッディン アハメド， | フルベストラント組成物 |
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| WO2016004369A1 (en) | 2014-07-02 | 2016-01-07 | The Research Foundation For The State University Of New York | Surfactant-stripped micelle compositions with high cargo to surfactant ratio |
| CN104434808A (zh) | 2014-07-03 | 2015-03-25 | 石药集团中奇制药技术（石家庄）有限公司 | 一种治疗性纳米粒子及其制备方法 |
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- 2017-05-05 US US16/099,265 patent/US20190134059A1/en not_active Abandoned
- 2017-05-05 KR KR1020187034942A patent/KR102438425B1/ko active Active
- 2017-05-05 UA UAA201812019A patent/UA125514C2/uk unknown
- 2017-05-05 MA MA044862A patent/MA44862A/fr unknown
- 2017-05-05 AU AU2017261321A patent/AU2017261321B2/en active Active
- 2017-05-05 JP JP2019510578A patent/JP2019516789A/ja active Pending
- 2017-05-05 WO PCT/US2017/031376 patent/WO2017193048A1/en not_active Ceased
- 2017-05-05 MY MYPI2018703903A patent/MY205661A/en unknown
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2018
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2021
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2023
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| Publication number | Publication date |
|---|---|
| NZ747911A (en) | 2025-03-28 |
| IL262465A (en) | 2018-12-31 |
| JP2023109959A (ja) | 2023-08-08 |
| IL285928B1 (en) | 2025-02-01 |
| MA44862A (fr) | 2019-03-13 |
| AU2017261321B2 (en) | 2023-03-09 |
| MX2022013199A (es) | 2022-12-13 |
| US20210346396A1 (en) | 2021-11-11 |
| MX2018013414A (es) | 2019-06-06 |
| JP7312523B2 (ja) | 2023-07-21 |
| JP2019516789A (ja) | 2019-06-20 |
| RU2018142068A (ru) | 2020-06-08 |
| CN109310621A (zh) | 2019-02-05 |
| KR20190005183A (ko) | 2019-01-15 |
| UA125514C2 (uk) | 2022-04-13 |
| IL285928A (en) | 2021-10-31 |
| AU2023203392A1 (en) | 2023-06-29 |
| MY205661A (en) | 2024-11-04 |
| EP3452011A1 (en) | 2019-03-13 |
| KR102438425B1 (ko) | 2022-09-01 |
| CO2018013257A2 (es) | 2018-12-28 |
| BR112018072768A2 (pt) | 2019-02-19 |
| JP2021169510A (ja) | 2021-10-28 |
| ZA201807031B (en) | 2023-10-25 |
| WO2017193048A1 (en) | 2017-11-09 |
| US20190134059A1 (en) | 2019-05-09 |
| IL285928B2 (en) | 2025-06-01 |
| AU2017261321A1 (en) | 2018-11-15 |
| RU2018142068A3 (OSRAM) | 2020-09-17 |
| US12370199B2 (en) | 2025-07-29 |
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