CA2997673A1 - T-cell receptor (tcr)-binding antibodies and uses thereof - Google Patents
T-cell receptor (tcr)-binding antibodies and uses thereof Download PDFInfo
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- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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| ES2828982T3 (es) | 2013-05-14 | 2021-05-28 | Univ Texas | Aplicación humana de células t de receptor de antígeno quimérico (car) diseñadas |
| CA3190002A1 (en) | 2014-02-14 | 2015-08-20 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors and methods of making |
| EP3215534B1 (en) | 2014-11-05 | 2020-04-15 | Board of Regents, The University of Texas System | Chimeric antigen receptors (car) to selectively target protein complexes |
| CN107667169B (zh) | 2015-02-24 | 2021-10-29 | 得克萨斯州大学系统董事会 | 遗传修饰的t细胞的选择方法 |
| KR102615825B1 (ko) | 2015-03-11 | 2023-12-21 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 전위효소 폴리펩타이드 및 이의 용도 |
| EP3349791A1 (en) | 2015-09-15 | 2018-07-25 | Board of Regents, The University of Texas System | T-cell receptor (tcr)-binding antibodies and uses thereof |
| US11059879B2 (en) | 2015-10-27 | 2021-07-13 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor molecules and uses thereof |
| JP2020517259A (ja) * | 2017-04-19 | 2020-06-18 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 操作された抗原受容体を発現する免疫細胞 |
| WO2019084427A1 (en) * | 2017-10-27 | 2019-05-02 | Kite Pharma, Inc. | T-LYMPHOCYTE RECEPTOR ANTIGEN BINDING MOLECULES AND METHODS OF USE THEREOF |
| JP7273421B2 (ja) | 2018-02-21 | 2023-05-15 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 |
| US20210283180A1 (en) * | 2018-07-06 | 2021-09-16 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Car t cell therapy to target t cell specific cancers |
| CN109136282A (zh) * | 2018-09-30 | 2019-01-04 | 北京鼎成肽源生物技术有限公司 | 一种hafft1细胞的构建方法 |
| CN114360644B (zh) * | 2021-12-30 | 2024-12-17 | 山东师范大学 | T细胞受体与抗原表位的结合预测方法及系统 |
| CN117624340B (zh) * | 2024-01-23 | 2024-04-30 | 北京臻知医学科技有限责任公司 | 识别人乙型肝炎病毒（hbv）抗原的t细胞受体（tcr）及其用途 |
| WO2025247325A1 (en) * | 2024-05-30 | 2025-12-04 | Hanx Biopharmaceuticals, (Wuhan) Ltd. | Antibody-drug conjugates targeting trbv12 and uses thereof |
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| US10391126B2 (en) | 2011-11-18 | 2019-08-27 | Board Of Regents, The University Of Texas System | CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA |
| TWI745610B (zh) * | 2012-11-14 | 2021-11-11 | 美商再生元醫藥公司 | 重組細胞表面捕捉蛋白質 |
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| ES2828982T3 (es) | 2013-05-14 | 2021-05-28 | Univ Texas | Aplicación humana de células t de receptor de antígeno quimérico (car) diseñadas |
| WO2014190273A1 (en) | 2013-05-24 | 2014-11-27 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor-targeting monoclonal antibodies |
| CA2926859A1 (en) | 2013-10-25 | 2015-04-30 | Board Of Regents, The University Of Texas System | Polyclonal gamma delta t cells for immunotherapy |
| CA3190002A1 (en) | 2014-02-14 | 2015-08-20 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors and methods of making |
| US20170158749A1 (en) | 2014-04-23 | 2017-06-08 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) and methods for making and using the same |
| WO2015164740A1 (en) | 2014-04-24 | 2015-10-29 | Board Of Regents, The University Of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
| JP2017535284A (ja) | 2014-11-05 | 2017-11-30 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 免疫エフェクター細胞の拡大のための遺伝子改変免疫エフェクター細胞及び遺伝子操作細胞 |
| EP3215534B1 (en) | 2014-11-05 | 2020-04-15 | Board of Regents, The University of Texas System | Chimeric antigen receptors (car) to selectively target protein complexes |
| CN107667169B (zh) | 2015-02-24 | 2021-10-29 | 得克萨斯州大学系统董事会 | 遗传修饰的t细胞的选择方法 |
| KR102615825B1 (ko) | 2015-03-11 | 2023-12-21 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 전위효소 폴리펩타이드 및 이의 용도 |
| EP3349791A1 (en) | 2015-09-15 | 2018-07-25 | Board of Regents, The University of Texas System | T-cell receptor (tcr)-binding antibodies and uses thereof |
| US11059879B2 (en) | 2015-10-27 | 2021-07-13 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor molecules and uses thereof |
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| JP7020687B2 (ja) | 2022-02-16 |
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| JP2018528776A (ja) | 2018-10-04 |
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| KR20180042449A (ko) | 2018-04-25 |
| EP3349791A1 (en) | 2018-07-25 |
| US10633445B2 (en) | 2020-04-28 |
| IL258009B1 (en) | 2023-11-01 |
| HK1258218A1 (zh) | 2019-11-08 |
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| EEER | Examination request |
Effective date: 20210907 |
|
| EEER | Examination request |
Effective date: 20210907 |
|
| EEER | Examination request |
Effective date: 20210907 |