CA2994825A1 - Anti-cd154 antibodies and methods of using them - Google Patents
Anti-cd154 antibodies and methods of using them Download PDFInfo
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
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| US201662367660P | 2016-07-28 | 2016-07-28 | |
| US62/367,660 | 2016-07-28 | ||
| PCT/US2016/045574 WO2017024146A1 (en) | 2015-08-05 | 2016-08-04 | Anti-cd154 antibodies and methods of using them |
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| CA2994825A1 true CA2994825A1 (en) | 2017-02-09 |
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| AU2016301361B2 (en) * | 2015-08-05 | 2022-06-16 | Janssen Biotech, Inc. | Anti-CD154 antibodies and methods of using them |
| MX2018001557A (es) | 2015-08-05 | 2018-05-02 | Eisai R&D Man Co Ltd | Reactivos quirales para la preparacion de oligomeros homogeneos. |
| BR112018010802A2 (pt) | 2015-11-27 | 2018-11-27 | Ablynx Nv | polipeptídeos que inibem cd40l |
| WO2020068723A1 (en) * | 2018-09-24 | 2020-04-02 | Janssen Biotech, Inc. | Method of providing safe administration of an anti-cd154 antibody |
| US20220259278A1 (en) * | 2019-07-08 | 2022-08-18 | Progen Co., Ltd. | Novel fusion protein and use of same |
| US20230078330A1 (en) * | 2020-01-27 | 2023-03-16 | Vanderbilt University | Human anti-dengue antibodies and methods of use therefor |
| JP2023537225A (ja) * | 2020-07-28 | 2023-08-31 | エルジー・ケム・リミテッド | 抗－ｌｉｌｒｂ１抗体およびその用途 |
| CN115586338A (zh) * | 2022-09-20 | 2023-01-10 | 杭州赛基生物科技有限公司 | 用于检测可溶性细胞因子受体的试剂盒及其制备方法 |
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