CA2978081C - Proteins toxic to hemipteran insect species - Google Patents

Proteins toxic to hemipteran insect species Download PDF

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Publication number
CA2978081C
CA2978081C CA2978081A CA2978081A CA2978081C CA 2978081 C CA2978081 C CA 2978081C CA 2978081 A CA2978081 A CA 2978081A CA 2978081 A CA2978081 A CA 2978081A CA 2978081 C CA2978081 C CA 2978081C
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CA
Canada
Prior art keywords
seq
tic807
residue
deletion
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2978081A
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English (en)
French (fr)
Other versions
CA2978081A1 (en
Inventor
James A. Baum
Artem G. Evdokimov
Farhad Moshiri
Timothy J. Rydel
Eric J. Sturman
Moritz Von Rechenberg
Halong VU
Andrew M. WOLLACOTT
Meiying ZHENG
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Technology LLC
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Monsanto Technology LLC
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Publication date
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Publication of CA2978081A1 publication Critical patent/CA2978081A1/en
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Publication of CA2978081C publication Critical patent/CA2978081C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Insects & Arthropods (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pest Control & Pesticides (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Virology (AREA)
CA2978081A 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species Active CA2978081C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261621436P 2012-04-06 2012-04-06
US61/621,436 2012-04-06
CA2868815A CA2868815C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2868815A Division CA2868815C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Publications (2)

Publication Number Publication Date
CA2978081A1 CA2978081A1 (en) 2013-10-10
CA2978081C true CA2978081C (en) 2021-11-23

Family

ID=49293388

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2978081A Active CA2978081C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species
CA2868815A Active CA2868815C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2868815A Active CA2868815C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Country Status (18)

Country Link
US (10) US9322033B2 (OSRAM)
EP (2) EP3495379A1 (OSRAM)
JP (1) JP6106263B2 (OSRAM)
CN (1) CN104271595B (OSRAM)
AP (1) AP2014007975A0 (OSRAM)
AR (3) AR090622A1 (OSRAM)
AU (1) AU2013243348B2 (OSRAM)
BR (1) BR112014024861B1 (OSRAM)
CA (2) CA2978081C (OSRAM)
CO (1) CO7121319A2 (OSRAM)
CR (1) CR20140507A (OSRAM)
ES (1) ES2743916T3 (OSRAM)
IN (1) IN2014DN08695A (OSRAM)
MX (1) MX350050B (OSRAM)
SG (1) SG11201406327YA (OSRAM)
UY (1) UY34731A (OSRAM)
WO (1) WO2013152264A2 (OSRAM)
ZA (1) ZA201406919B (OSRAM)

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WO2013152264A2 (en) 2012-04-06 2013-10-10 Monsanto Technology Llc Proteins toxic to hemipteran insect species
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JP6648127B2 (ja) 2014-10-16 2020-02-14 モンサント テクノロジー エルエルシー 鱗翅類活性Ｃｒｙ１Ｄａ１アミノ酸配列変異体タンパク質
CN112175093B (zh) 2014-10-16 2024-08-27 孟山都技术有限公司 对鳞翅目害虫具有毒性或抑制性的嵌合杀昆虫蛋白质
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CN117624314A (zh) * 2022-09-01 2024-03-01 青岛清原种子科学有限公司 一种突变杀虫蛋白Vip3及其应用
CN118271409A (zh) * 2022-12-29 2024-07-02 青岛清原化合物有限公司 一种Cry51Aa1蛋白及其在控制害虫上的应用
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US12389867B2 (en) 2022-12-30 2025-08-19 Monsanto Technology Llc Cotton variety 21R4127B3TXF
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Also Published As

Publication number Publication date
CA2868815C (en) 2017-10-24
JP2015514116A (ja) 2015-05-18
US10188115B2 (en) 2019-01-29
ZA201406919B (en) 2019-12-18
MX350050B (es) 2017-08-23
WO2013152264A3 (en) 2013-11-21
US12319716B2 (en) 2025-06-03
CO7121319A2 (es) 2014-11-20
US20170318818A1 (en) 2017-11-09
AR090622A1 (es) 2014-11-26
AR118722A2 (es) 2021-10-27
US11459359B2 (en) 2022-10-04
CA2978081A1 (en) 2013-10-10
UY34731A (es) 2013-11-29
AU2013243348A1 (en) 2014-10-30
ES2743916T3 (es) 2020-02-21
EP3495379A1 (en) 2019-06-12
WO2013152264A2 (en) 2013-10-10
US20250320260A1 (en) 2025-10-16
US20220356215A1 (en) 2022-11-10
CN104271595B (zh) 2018-09-18
BR112014024861B1 (pt) 2021-11-16
US20220356214A1 (en) 2022-11-10
IN2014DN08695A (OSRAM) 2015-05-22
US9713334B2 (en) 2017-07-25
CA2868815A1 (en) 2013-10-10
US20190098903A1 (en) 2019-04-04
CN104271595A (zh) 2015-01-07
US9322033B2 (en) 2016-04-26
AR118723A2 (es) 2021-10-27
EP2834266A2 (en) 2015-02-11
AP2014007975A0 (en) 2014-09-30
US20130269060A1 (en) 2013-10-10
SG11201406327YA (en) 2014-11-27
CR20140507A (es) 2014-12-01
US11981709B2 (en) 2024-05-14
EP2834266B1 (en) 2019-06-12
US20200022376A1 (en) 2020-01-23
BR112014024861A2 (pt) 2020-11-24
JP6106263B2 (ja) 2017-03-29
US20160150795A1 (en) 2016-06-02
EP2834266A4 (en) 2016-02-24
US10897910B2 (en) 2021-01-26
US20240262872A1 (en) 2024-08-08
US10485238B2 (en) 2019-11-26
MX2014012026A (es) 2014-12-05
US20210100249A1 (en) 2021-04-08
AU2013243348B2 (en) 2017-06-29
US12054522B2 (en) 2024-08-06

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