CR20140507A - Proteinas toxicas para especies de insectos hemipteros - Google Patents

Proteinas toxicas para especies de insectos hemipteros

Info

Publication number
CR20140507A
CR20140507A CR20140507A CR20140507A CR20140507A CR 20140507 A CR20140507 A CR 20140507A CR 20140507 A CR20140507 A CR 20140507A CR 20140507 A CR20140507 A CR 20140507A CR 20140507 A CR20140507 A CR 20140507A
Authority
CR
Costa Rica
Prior art keywords
hemipter
proteins
insect species
toxic proteins
methods
Prior art date
Application number
CR20140507A
Other languages
English (en)
Spanish (es)
Inventor
James A Baum
Artem G Evdokimov
Farhad Moshiri
Timothy J Rydel
Eric J Sturman
Rechenberg Moritz Von
Halong Vu
Andrew M Wollacott
Meiying Zheng
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of CR20140507A publication Critical patent/CR20140507A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Insects & Arthropods (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pest Control & Pesticides (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Virology (AREA)
CR20140507A 2012-04-06 2014-11-03 Proteinas toxicas para especies de insectos hemipteros CR20140507A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261621436P 2012-04-06 2012-04-06
PCT/US2013/035388 WO2013152264A2 (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Publications (1)

Publication Number Publication Date
CR20140507A true CR20140507A (es) 2014-12-01

Family

ID=49293388

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20140507A CR20140507A (es) 2012-04-06 2014-11-03 Proteinas toxicas para especies de insectos hemipteros

Country Status (18)

Country Link
US (10) US9322033B2 (OSRAM)
EP (2) EP2834266B1 (OSRAM)
JP (1) JP6106263B2 (OSRAM)
CN (1) CN104271595B (OSRAM)
AP (1) AP2014007975A0 (OSRAM)
AR (3) AR090622A1 (OSRAM)
AU (1) AU2013243348B2 (OSRAM)
BR (1) BR112014024861B1 (OSRAM)
CA (2) CA2868815C (OSRAM)
CO (1) CO7121319A2 (OSRAM)
CR (1) CR20140507A (OSRAM)
ES (1) ES2743916T3 (OSRAM)
IN (1) IN2014DN08695A (OSRAM)
MX (1) MX350050B (OSRAM)
SG (1) SG11201406327YA (OSRAM)
UY (1) UY34731A (OSRAM)
WO (1) WO2013152264A2 (OSRAM)
ZA (1) ZA201406919B (OSRAM)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8609936B2 (en) 2007-04-27 2013-12-17 Monsanto Technology Llc Hemipteran-and coleopteran active toxin proteins from Bacillus thuringiensis
WO2012139004A2 (en) 2011-04-07 2012-10-11 Monsanto Technology Llc Insect inhibitory toxin family active against hemipteran and/or lepidopteran insects
EP2834266B1 (en) 2012-04-06 2019-06-12 Monsanto Technology LLC Proteins toxic to hemipteran insect species
WO2015021354A2 (en) * 2013-08-09 2015-02-12 Monsanto Technology Llc Pesticidal toxin active against coleopteran and/or hemipteran insects
WO2015148976A1 (en) 2014-03-28 2015-10-01 Monsanto Technology Llc Pesticidal toxin proteins active against coleopteran insects
KR102127553B1 (ko) 2014-10-16 2020-06-29 몬산토 테크놀로지 엘엘씨 인시류 해충에 대해서 유독성이거나 저해성인 신규한 키메릭 살곤충 단백질
US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
WO2016061392A1 (en) 2014-10-16 2016-04-21 Monsanto Technology Llc Proteins toxic or inhibitory to lepidopteran insects
CN106852147B (zh) 2014-10-16 2021-08-27 孟山都技术有限公司 鳞翅目活性Cry1Da1氨基酸序列变异蛋白
US11130964B2 (en) 2014-11-20 2021-09-28 Monsanto Technology Llc Insect inhibitory proteins
RU2740313C2 (ru) 2014-11-20 2021-01-13 Монсанто Текнолоджи Ллс Новые белки, обладающие ингибирующей активностью в отношении насекомых
CN107529763B (zh) * 2015-03-11 2021-08-20 先锋国际良种公司 Pip-72的杀昆虫组合及使用方法
US20180216131A1 (en) * 2015-03-27 2018-08-02 Institute Of Cotton Research, Chinese Academy Of Agricultural Sciences Artificially synthesized insect-resistant protein, biological materials associated therewith, and use thereof
WO2017030808A1 (en) 2015-08-18 2017-02-23 Monsanto Technology Llc Novel insect inhibitory proteins
EP3349582B1 (en) 2015-08-27 2021-08-11 Monsanto Technology LLC Novel insect inhibitory proteins
ES2961522T3 (es) * 2015-11-02 2024-03-12 Monsanto Technology Llc Evento transgénico de algodón MON 88702 y procedimientos para su detección y usos
EP3451837B1 (en) 2016-05-04 2021-08-25 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CN106434948B (zh) * 2016-10-26 2019-10-18 广西壮族自治区农业科学院水稻研究所 水稻抗褐飞虱基因Bph31(t)的分子标记及其应用
EP3585171A4 (en) * 2017-02-24 2020-08-26 Flagship Pioneering Innovations V, Inc. COMPOSITIONS AND ASSOCIATED PROCESSES FOR THE MODULATION OF ENDOSYMBIONTES
US20190276840A1 (en) 2018-03-09 2019-09-12 James A. Baum Methods and compositions for making and using compatible insecticidal proteins
EP3764798B1 (en) 2018-03-14 2025-12-17 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
US11820791B2 (en) 2018-03-14 2023-11-21 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
BR112022027035A2 (pt) 2020-07-14 2023-04-11 Pioneer Hi Bred Int Proteínas inseticidas e métodos para uso das mesmas
CN112410346B (zh) * 2020-11-30 2023-07-25 中国计量大学 一种提升生防真菌杀虫毒力的方法
AU2021409634A1 (en) 2020-12-21 2023-07-06 Monsanto Technology Llc Novel insect inhibitory proteins
UY39585A (es) 2020-12-23 2022-07-29 Monsanto Technology Llc Proteínas que exhiben actividad inhibidora de insectos frente a plagas con importancia agrícola de plantas de cultivo y semillas
WO2022146874A1 (en) 2020-12-31 2022-07-07 Monsanto Technology Llc Novel insect inhibitory proteins
WO2023283103A1 (en) 2021-07-08 2023-01-12 Monsanto Technology Llc Novel insect inhibitory proteins
US12075745B2 (en) 2021-12-23 2024-09-03 Monsanto Technology Llc Cotton variety 19R325B3TXF
US12356950B2 (en) 2021-12-23 2025-07-15 Monsanto Technology Llc Cotton variety 20R816B3TXF
US12193404B2 (en) 2022-01-26 2025-01-14 Monsanto Technology Llc Cotton variety 20R828B3TXF
US12102052B2 (en) 2022-01-26 2024-10-01 Monsanto Technology Llc Cotton variety 20R827B3TXF
US12382917B2 (en) 2022-01-26 2025-08-12 Monsanto Technology Llc Cotton variety 20R821B3TXF
US12108730B2 (en) 2022-01-26 2024-10-08 Monsanto Technology Llc Cotton variety 19R316B3TXF
US12369556B2 (en) 2022-01-26 2025-07-29 Monsanto Technology Llc Cotton variety 19R311B3TXF
US12245568B2 (en) 2022-01-26 2025-03-11 Monsanto Technology Llc Cotton variety 19R331B3TXF
US12108731B2 (en) 2022-01-26 2024-10-08 Monsanto Technology Llc Cotton variety 20R824B3TXF
CA3262019A1 (en) * 2022-09-01 2025-06-13 Qingdao Kingagroot Seed Science Co., Ltd. A mutant insecticidal protein Vip3 and its application
WO2024140065A1 (zh) * 2022-12-29 2024-07-04 青岛清原化合物有限公司 一种Cry51Aa1蛋白及其在控制害虫上的应用
US12284976B2 (en) 2022-12-30 2025-04-29 Monsanto Technology Llc Cotton variety 21R4132B3TXF
US12389867B2 (en) 2022-12-30 2025-08-19 Monsanto Technology Llc Cotton variety 21R4127B3TXF
US12433235B2 (en) 2023-01-26 2025-10-07 Monsanto Technology Llc Cotton variety 21R4432B3TXF
US12419263B2 (en) 2023-01-26 2025-09-23 Monsanto Technology Llc Cotton variety 21R4126B3TXF
US12419262B2 (en) 2023-01-26 2025-09-23 Monsanto Technology Llc Cotton variety 21R4221B3TXF
US12439883B2 (en) 2023-01-26 2025-10-14 Monsanto Technology Llc Cotton variety 21R4534B3TXF
WO2025178772A1 (en) 2024-02-23 2025-08-28 Genective Sa Insecticidal proteins compositions and methods of use
WO2025193453A1 (en) 2024-03-14 2025-09-18 Genective Sa Insecticidal proteins compositions and methods of use
WO2025235220A1 (en) 2024-05-08 2025-11-13 Genective Sa Insecticidal proteins compositions and methods of use

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE71183B1 (en) 1988-12-27 1997-01-29 Takeda Chemical Industries Ltd Guanidine derivatives their production and insecticides
AU638438B2 (en) 1989-02-24 1993-07-01 Monsanto Technology Llc Synthetic plant genes and method for preparation
TW198724B (OSRAM) 1990-10-24 1993-01-21 Ciba Geigy Ag
US5308760A (en) 1992-01-10 1994-05-03 Washington Research Foundation Crystal proteins of Bacillus thuringiensis, genes encoding them, and host expressing them
TW240163B (en) 1992-07-22 1995-02-11 Syngenta Participations Ag Oxadiazine derivatives
US5322687A (en) 1993-07-29 1994-06-21 Ecogen Inc. Bacillus thuringiensis cryet4 and cryet5 toxin genes and proteins toxic to lepidopteran insects
FR2729825A1 (fr) 1995-01-30 1996-08-02 Rhone Poulenc Agrochimie Associations insecticides comprenant un insecticide de la famille des chloronicotinyls et un insecticide a groupe pyrazole,pyrrole ou phenylimidazole pour traiter les semences ou le sol
US5723440A (en) 1995-06-07 1998-03-03 Mycogen Corporation Controlling hemipteran insect pests with Bacillus thuringiensis
AU2001245945A1 (en) 2000-03-23 2001-10-03 Pe Corporation (Ny) Detection kits, such as nucleic acid arrays, for detecting the expression of 10,000 or more drosophila genes and uses thereof
CN101385467B (zh) * 2001-03-30 2014-11-05 辛根塔参与股份公司 新的杀虫毒素
AR035799A1 (es) 2001-03-30 2004-07-14 Syngenta Participations Ag Toxinas insecticidas aisladas de bacillus thuringiensis y sus usos.
US7524810B1 (en) 2003-10-03 2009-04-28 Dow Agrosciences Llc Modified Cry34 proteins
US20060021087A1 (en) 2004-04-09 2006-01-26 Baum James A Compositions and methods for control of insect infestations in plants
EP1871788B1 (en) 2005-04-01 2009-09-16 Athenix Corporation Axmi-027 a family of delta-endotoxin genes and methods for their use
EP1893638B1 (en) 2005-06-08 2011-08-10 Pioneer-Hi-Bred International, Inc. Insect-specific protease recognition sequences
ATE505548T1 (de) 2005-08-31 2011-04-15 Monsanto Technology Llc Insektizidzusammensetzungen und verfahren zur herstellung von insektenbeständigen transgenen pflanzen
US8609936B2 (en) 2007-04-27 2013-12-17 Monsanto Technology Llc Hemipteran-and coleopteran active toxin proteins from Bacillus thuringiensis
WO2010025320A1 (en) * 2008-08-29 2010-03-04 Monsanto Technology Llc Novel hemipteran and coleopteran active toxin proteins from bacillus thuringiensis
BRPI1008740A8 (pt) 2009-02-27 2022-07-05 Athenix Corp Proteínas pesticidas e métodos para seu uso.
WO2012139004A2 (en) 2011-04-07 2012-10-11 Monsanto Technology Llc Insect inhibitory toxin family active against hemipteran and/or lepidopteran insects
EP2834266B1 (en) 2012-04-06 2019-06-12 Monsanto Technology LLC Proteins toxic to hemipteran insect species

Also Published As

Publication number Publication date
SG11201406327YA (en) 2014-11-27
US20170318818A1 (en) 2017-11-09
AU2013243348A1 (en) 2014-10-30
BR112014024861A2 (pt) 2020-11-24
US12054522B2 (en) 2024-08-06
MX350050B (es) 2017-08-23
US20130269060A1 (en) 2013-10-10
US20220356215A1 (en) 2022-11-10
US20160150795A1 (en) 2016-06-02
US20240262872A1 (en) 2024-08-08
CA2868815A1 (en) 2013-10-10
CO7121319A2 (es) 2014-11-20
JP2015514116A (ja) 2015-05-18
US9322033B2 (en) 2016-04-26
ZA201406919B (en) 2019-12-18
AR118723A2 (es) 2021-10-27
US10897910B2 (en) 2021-01-26
AU2013243348B2 (en) 2017-06-29
CA2978081A1 (en) 2013-10-10
MX2014012026A (es) 2014-12-05
EP2834266A4 (en) 2016-02-24
IN2014DN08695A (OSRAM) 2015-05-22
WO2013152264A2 (en) 2013-10-10
UY34731A (es) 2013-11-29
AP2014007975A0 (en) 2014-09-30
JP6106263B2 (ja) 2017-03-29
US20250320260A1 (en) 2025-10-16
US10485238B2 (en) 2019-11-26
EP3495379A1 (en) 2019-06-12
AR090622A1 (es) 2014-11-26
US9713334B2 (en) 2017-07-25
US20200022376A1 (en) 2020-01-23
ES2743916T3 (es) 2020-02-21
US11981709B2 (en) 2024-05-14
WO2013152264A3 (en) 2013-11-21
US12319716B2 (en) 2025-06-03
BR112014024861B1 (pt) 2021-11-16
CA2868815C (en) 2017-10-24
US10188115B2 (en) 2019-01-29
AR118722A2 (es) 2021-10-27
EP2834266B1 (en) 2019-06-12
US20220356214A1 (en) 2022-11-10
US11459359B2 (en) 2022-10-04
CA2978081C (en) 2021-11-23
US20210100249A1 (en) 2021-04-08
CN104271595A (zh) 2015-01-07
CN104271595B (zh) 2018-09-18
EP2834266A2 (en) 2015-02-11
US20190098903A1 (en) 2019-04-04

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