CA2868815C - Proteins toxic to hemipteran insect species - Google Patents

Proteins toxic to hemipteran insect species Download PDF

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Publication number
CA2868815C
CA2868815C CA2868815A CA2868815A CA2868815C CA 2868815 C CA2868815 C CA 2868815C CA 2868815 A CA2868815 A CA 2868815A CA 2868815 A CA2868815 A CA 2868815A CA 2868815 C CA2868815 C CA 2868815C
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Canada
Prior art keywords
seq
tic807
residue
deletion
range
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CA2868815A
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English (en)
French (fr)
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CA2868815A1 (en
Inventor
James A. Baum
Artem G. Evdokimov
Farhad Moshiri
Timothy J. Rydel
Eric J. Sturman
Moritz Von Rechenberg
Halong VU
Andrew M. WOLLACOTT
Meiying ZHENG
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Monsanto Technology LLC
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Monsanto Technology LLC
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Publication date
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Priority to CA2978081A priority Critical patent/CA2978081C/en
Publication of CA2868815A1 publication Critical patent/CA2868815A1/en
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Publication of CA2868815C publication Critical patent/CA2868815C/en
Active legal-status Critical Current
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46N-acyl derivatives
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44Guanidine; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Insects & Arthropods (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pest Control & Pesticides (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Virology (AREA)
CA2868815A 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species Active CA2868815C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2978081A CA2978081C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261621436P 2012-04-06 2012-04-06
US61/621,436 2012-04-06
PCT/US2013/035388 WO2013152264A2 (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2978081A Division CA2978081C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Publications (2)

Publication Number Publication Date
CA2868815A1 CA2868815A1 (en) 2013-10-10
CA2868815C true CA2868815C (en) 2017-10-24

Family

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Family Applications (2)

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CA2868815A Active CA2868815C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species
CA2978081A Active CA2978081C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Family Applications After (1)

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CA2978081A Active CA2978081C (en) 2012-04-06 2013-04-05 Proteins toxic to hemipteran insect species

Country Status (18)

Country Link
US (10) US9322033B2 (OSRAM)
EP (2) EP2834266B1 (OSRAM)
JP (1) JP6106263B2 (OSRAM)
CN (1) CN104271595B (OSRAM)
AP (1) AP2014007975A0 (OSRAM)
AR (3) AR090622A1 (OSRAM)
AU (1) AU2013243348B2 (OSRAM)
BR (1) BR112014024861B1 (OSRAM)
CA (2) CA2868815C (OSRAM)
CO (1) CO7121319A2 (OSRAM)
CR (1) CR20140507A (OSRAM)
ES (1) ES2743916T3 (OSRAM)
IN (1) IN2014DN08695A (OSRAM)
MX (1) MX350050B (OSRAM)
SG (1) SG11201406327YA (OSRAM)
UY (1) UY34731A (OSRAM)
WO (1) WO2013152264A2 (OSRAM)
ZA (1) ZA201406919B (OSRAM)

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EP2834266B1 (en) 2012-04-06 2019-06-12 Monsanto Technology LLC Proteins toxic to hemipteran insect species
WO2015021354A2 (en) * 2013-08-09 2015-02-12 Monsanto Technology Llc Pesticidal toxin active against coleopteran and/or hemipteran insects
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US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
WO2016061392A1 (en) 2014-10-16 2016-04-21 Monsanto Technology Llc Proteins toxic or inhibitory to lepidopteran insects
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US12245568B2 (en) 2022-01-26 2025-03-11 Monsanto Technology Llc Cotton variety 19R331B3TXF
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CA3262019A1 (en) * 2022-09-01 2025-06-13 Qingdao Kingagroot Seed Science Co., Ltd. A mutant insecticidal protein Vip3 and its application
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US12284976B2 (en) 2022-12-30 2025-04-29 Monsanto Technology Llc Cotton variety 21R4132B3TXF
US12389867B2 (en) 2022-12-30 2025-08-19 Monsanto Technology Llc Cotton variety 21R4127B3TXF
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Also Published As

Publication number Publication date
SG11201406327YA (en) 2014-11-27
US20170318818A1 (en) 2017-11-09
AU2013243348A1 (en) 2014-10-30
BR112014024861A2 (pt) 2020-11-24
US12054522B2 (en) 2024-08-06
MX350050B (es) 2017-08-23
US20130269060A1 (en) 2013-10-10
US20220356215A1 (en) 2022-11-10
US20160150795A1 (en) 2016-06-02
US20240262872A1 (en) 2024-08-08
CA2868815A1 (en) 2013-10-10
CO7121319A2 (es) 2014-11-20
JP2015514116A (ja) 2015-05-18
US9322033B2 (en) 2016-04-26
ZA201406919B (en) 2019-12-18
AR118723A2 (es) 2021-10-27
US10897910B2 (en) 2021-01-26
AU2013243348B2 (en) 2017-06-29
CA2978081A1 (en) 2013-10-10
MX2014012026A (es) 2014-12-05
EP2834266A4 (en) 2016-02-24
IN2014DN08695A (OSRAM) 2015-05-22
WO2013152264A2 (en) 2013-10-10
UY34731A (es) 2013-11-29
AP2014007975A0 (en) 2014-09-30
JP6106263B2 (ja) 2017-03-29
US20250320260A1 (en) 2025-10-16
US10485238B2 (en) 2019-11-26
EP3495379A1 (en) 2019-06-12
AR090622A1 (es) 2014-11-26
US9713334B2 (en) 2017-07-25
US20200022376A1 (en) 2020-01-23
ES2743916T3 (es) 2020-02-21
US11981709B2 (en) 2024-05-14
WO2013152264A3 (en) 2013-11-21
US12319716B2 (en) 2025-06-03
BR112014024861B1 (pt) 2021-11-16
US10188115B2 (en) 2019-01-29
AR118722A2 (es) 2021-10-27
EP2834266B1 (en) 2019-06-12
US20220356214A1 (en) 2022-11-10
US11459359B2 (en) 2022-10-04
CA2978081C (en) 2021-11-23
US20210100249A1 (en) 2021-04-08
CN104271595A (zh) 2015-01-07
CN104271595B (zh) 2018-09-18
CR20140507A (es) 2014-12-01
EP2834266A2 (en) 2015-02-11
US20190098903A1 (en) 2019-04-04

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