CA2967224C - Binding members for human c-maf - Google Patents
Binding members for human c-maf Download PDFInfo
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- CA2967224C CA2967224C CA2967224A CA2967224A CA2967224C CA 2967224 C CA2967224 C CA 2967224C CA 2967224 A CA2967224 A CA 2967224A CA 2967224 A CA2967224 A CA 2967224A CA 2967224 C CA2967224 C CA 2967224C
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- binding member
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- A61P35/00—Antineoplastic agents
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- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/82—Translation products from oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462090599P | 2014-12-11 | 2014-12-11 | |
| US62/090,599 | 2014-12-11 | ||
| PCT/IB2015/059562 WO2016092524A1 (en) | 2014-12-11 | 2015-12-11 | Binding members for human c-maf |
Publications (2)
| Publication Number | Publication Date |
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| CA2967224A1 CA2967224A1 (en) | 2016-06-16 |
| CA2967224C true CA2967224C (en) | 2023-08-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2967224A Active CA2967224C (en) | 2014-12-11 | 2015-12-11 | Binding members for human c-maf |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10793642B2 (OSRAM) |
| EP (1) | EP3229909B1 (OSRAM) |
| JP (1) | JP2017538412A (OSRAM) |
| KR (1) | KR20170093182A (OSRAM) |
| CN (1) | CN107001480B (OSRAM) |
| AU (1) | AU2015358868A1 (OSRAM) |
| BR (1) | BR112017012515A2 (OSRAM) |
| CA (1) | CA2967224C (OSRAM) |
| MX (1) | MX2017007381A (OSRAM) |
| WO (1) | WO2016092524A1 (OSRAM) |
Families Citing this family (9)
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| EP3517630B1 (en) | 2010-10-06 | 2022-01-19 | Institució Catalana de Recerca i Estudis Avançats | Method for the diagnosis, prognosis and treatment of breast cancer metastasis |
| EP2650682A1 (en) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Method for the prognosis and treatment of cancer metastasis |
| EP3467124A1 (en) | 2012-06-06 | 2019-04-10 | Fundació Institut de Recerca Biomèdica IRB (Barcelona) | Method for the diagnosis, prognosis and treatment of lung cancer metastasis |
| US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
| ES2744244T3 (es) | 2012-10-12 | 2020-02-24 | Inbiomotion Sl | Método para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de próstata usando c-MAF |
| EP3272880B1 (en) | 2013-03-15 | 2020-11-25 | Fundació Institut de Recerca Biomèdica (IRB Barcelona) | Method for the diagnosis, prognosis and treatment of metastatic cancer |
| CN107001480B (zh) | 2014-12-11 | 2021-12-03 | 生物运动有限公司 | 用于人c-maf的结合成员 |
| KR102867720B1 (ko) | 2016-05-25 | 2025-10-01 | 인바이오모션 에스.엘. | c-MAF 상태에 기초한 유방암의 치료 |
| KR20200104298A (ko) | 2017-11-22 | 2020-09-03 | 인바이오모션 에스.엘. | c-MAF 상태에 기반한 유방암의 요법 치료 |
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| US5814468A (en) | 1996-03-27 | 1998-09-29 | Coulter International Corp. | Methods of enumerating receptor molecules for specific binding partners on formed bodies and in solution |
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| CA2274987C (en) | 1996-12-23 | 2012-01-24 | Immunex Corporation | Ligand for receptor activator of nf-kappa b, ligand is member of tnf superfamily |
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| US6274338B1 (en) * | 1998-02-24 | 2001-08-14 | President And Fellows Of Harvard College | Human c-Maf compositions and methods of use thereof |
| ATE439592T1 (de) | 1998-12-10 | 2009-08-15 | Bristol Myers Squibb Co | Proteingerüste für antikörper-nachahmer und andere bindende proteine |
| YU66101A (sh) | 1999-03-15 | 2004-07-15 | Axys Pharmaceuticals Inc. | Nova jedinjenja i kompozicije kao inhibitori proteaze |
| ATE387199T1 (de) | 2000-01-06 | 2008-03-15 | Merck Frosst Canada Ltd | Neue substanzen und verbindungen als protease- inhibitoren |
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| NZ530765A (en) | 2001-06-26 | 2006-11-30 | Amgen Fremont Inc | Antibodies that bind OPGL and compositions and methods for the treatment of bone diseases |
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| GB0121033D0 (en) | 2001-08-30 | 2001-10-24 | Novartis Ag | Organic compounds |
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| SE0201980D0 (sv) | 2002-06-24 | 2002-06-24 | Astrazeneca Ab | Novel compounds |
| WO2005046731A1 (en) | 2003-10-17 | 2005-05-26 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Interference with c-maf function in multiple myeloma |
| WO2005060722A2 (en) | 2003-12-18 | 2005-07-07 | President And Fellows Of Hardvard College | Modulation of immune system function by modulation of polypeptide arginine methyltransferases |
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| EP1777523A1 (en) | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| EP2046971B1 (en) | 2006-06-30 | 2012-04-04 | University Of Southern California | Quantifiable internal reference standards for immunohistochemistry and uses thereof |
| WO2008086800A2 (en) | 2007-01-15 | 2008-07-24 | Aarhus Universitet | Predisposition to, prognosis for and treatment of breast cancer relating to human chromosome 16 |
| WO2008098351A1 (en) | 2007-02-14 | 2008-08-21 | University Health Network | Treatment of d-cyclin mediated proliferative diseases and hemotological malignancies |
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| CN101796072B (zh) | 2007-05-24 | 2014-09-24 | 埃博灵克斯股份有限公司 | 用于治疗骨疾病和病症的针对rank-l的氨基酸序列以及包括其的多肽 |
| RU2011101378A (ru) | 2008-06-16 | 2012-07-27 | Сайвидон Дайагностикс Гмбх (De) | Алгоритмы предсказания исхода у пациентов с узловой формой рака молочной железы после химиотерапии |
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| EP3517630B1 (en) | 2010-10-06 | 2022-01-19 | Institució Catalana de Recerca i Estudis Avançats | Method for the diagnosis, prognosis and treatment of breast cancer metastasis |
| EP2671076A4 (en) | 2011-02-04 | 2016-11-16 | Bioarray Genetics Inc | METHODS OF USING GENE EXPRESSION SIGNATURES FOR SELECTING A TREATMENT METHOD, PREDICTING PROGNOSIS, SURVIVAL, AND / OR PREDICTING A RESPONSE TO TREATMENT |
| EP2650682A1 (en) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Method for the prognosis and treatment of cancer metastasis |
| EP3467124A1 (en) * | 2012-06-06 | 2019-04-10 | Fundació Institut de Recerca Biomèdica IRB (Barcelona) | Method for the diagnosis, prognosis and treatment of lung cancer metastasis |
| US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
| ES2744244T3 (es) * | 2012-10-12 | 2020-02-24 | Inbiomotion Sl | Método para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de próstata usando c-MAF |
| WO2014140933A2 (en) | 2013-03-15 | 2014-09-18 | Fundacio Privada Institut De Recerca Biomedica | Method for the prognosis and treatment of cancer metastasis |
| WO2014184679A2 (en) | 2013-03-15 | 2014-11-20 | Inbiomotion S.L. | Method for the prognosis and treatment of renal cell carcinoma metastasis |
| EP3272880B1 (en) | 2013-03-15 | 2020-11-25 | Fundació Institut de Recerca Biomèdica (IRB Barcelona) | Method for the diagnosis, prognosis and treatment of metastatic cancer |
| AU2014333513B2 (en) | 2013-10-09 | 2020-11-26 | Fundacio Institut De Recerca Biomedica (Irb Barcelona) | Method for the prognosis and treatment of metastasizing cancer of the bone originating from breast cancer |
| CN107001480B (zh) | 2014-12-11 | 2021-12-03 | 生物运动有限公司 | 用于人c-maf的结合成员 |
| KR102867720B1 (ko) | 2016-05-25 | 2025-10-01 | 인바이오모션 에스.엘. | c-MAF 상태에 기초한 유방암의 치료 |
| KR20200104298A (ko) | 2017-11-22 | 2020-09-03 | 인바이오모션 에스.엘. | c-MAF 상태에 기반한 유방암의 요법 치료 |
-
2015
- 2015-12-11 CN CN201580067068.4A patent/CN107001480B/zh active Active
- 2015-12-11 WO PCT/IB2015/059562 patent/WO2016092524A1/en not_active Ceased
- 2015-12-11 MX MX2017007381A patent/MX2017007381A/es unknown
- 2015-12-11 US US15/534,893 patent/US10793642B2/en active Active
- 2015-12-11 AU AU2015358868A patent/AU2015358868A1/en not_active Abandoned
- 2015-12-11 EP EP15816535.7A patent/EP3229909B1/en active Active
- 2015-12-11 JP JP2017530686A patent/JP2017538412A/ja active Pending
- 2015-12-11 BR BR112017012515A patent/BR112017012515A2/pt not_active Application Discontinuation
- 2015-12-11 CA CA2967224A patent/CA2967224C/en active Active
- 2015-12-11 KR KR1020177018132A patent/KR20170093182A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CN107001480A (zh) | 2017-08-01 |
| EP3229909B1 (en) | 2020-10-14 |
| US20170369589A1 (en) | 2017-12-28 |
| BR112017012515A2 (pt) | 2018-01-02 |
| EP3229909A1 (en) | 2017-10-18 |
| JP2017538412A (ja) | 2017-12-28 |
| KR20170093182A (ko) | 2017-08-14 |
| CN107001480B (zh) | 2021-12-03 |
| US10793642B2 (en) | 2020-10-06 |
| AU2015358868A1 (en) | 2017-06-01 |
| MX2017007381A (es) | 2017-11-06 |
| WO2016092524A1 (en) | 2016-06-16 |
| CA2967224A1 (en) | 2016-06-16 |
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