CA2963327A1 - Method for modulating car-induced immune cells activity - Google Patents

Method for modulating car-induced immune cells activity Download PDF

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Publication number
CA2963327A1
CA2963327A1 CA2963327A CA2963327A CA2963327A1 CA 2963327 A1 CA2963327 A1 CA 2963327A1 CA 2963327 A CA2963327 A CA 2963327A CA 2963327 A CA2963327 A CA 2963327A CA 2963327 A1 CA2963327 A1 CA 2963327A1
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Prior art keywords
car
immune cell
imp
domain
inhibitory
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Abandoned
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CA2963327A
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English (en)
French (fr)
Inventor
Philippe Duchateau
Alexandre Juillerat
Laurent Poirot
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Cellectis SA
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Cellectis SA
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    • A61K40/00Cellular immunotherapy
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    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/00Cellular immunotherapy
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    • A61K40/31Chimeric antigen receptors [CAR]
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A61K2239/23On/off switch
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    • C07K2317/622Single chain antibody (scFv)
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    • C12N2740/10011Retroviridae
    • C12N2740/10041Use of virus, viral particle or viral elements as a vector
    • C12N2740/10043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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CA2963327A 2014-10-07 2015-10-07 Method for modulating car-induced immune cells activity Abandoned CA2963327A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201470623 2014-10-07
DKPA201470623 2014-10-07
PCT/EP2015/073197 WO2016055551A1 (en) 2014-10-07 2015-10-07 Method for modulating car-induced immune cells activity

Publications (1)

Publication Number Publication Date
CA2963327A1 true CA2963327A1 (en) 2016-04-14

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CA2963327A Abandoned CA2963327A1 (en) 2014-10-07 2015-10-07 Method for modulating car-induced immune cells activity

Country Status (12)

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US (1) US10472613B2 (enExample)
EP (1) EP3204491A1 (enExample)
JP (1) JP2017531430A (enExample)
KR (1) KR20170068539A (enExample)
CN (1) CN107109368A (enExample)
AU (1) AU2015330017A1 (enExample)
BR (1) BR112017007003A2 (enExample)
CA (1) CA2963327A1 (enExample)
IL (1) IL251429A0 (enExample)
MX (1) MX2017004603A (enExample)
RU (1) RU2017115808A (enExample)
WO (1) WO2016055551A1 (enExample)

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US20170292118A1 (en) 2017-10-12
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