CA2961208A1 - Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression - Google Patents

Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression Download PDF

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Publication number
CA2961208A1
CA2961208A1 CA2961208A CA2961208A CA2961208A1 CA 2961208 A1 CA2961208 A1 CA 2961208A1 CA 2961208 A CA2961208 A CA 2961208A CA 2961208 A CA2961208 A CA 2961208A CA 2961208 A1 CA2961208 A1 CA 2961208A1
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CA
Canada
Prior art keywords
val
esketamine
treatment
met
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2961208A
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English (en)
French (fr)
Inventor
Lodewijk Ivo Caers
Giacomo SALVADORE
Jaskaran Singh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54200096&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2961208(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of CA2961208A1 publication Critical patent/CA2961208A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2961208A 2014-09-15 2015-09-14 Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression Abandoned CA2961208A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462050439P 2014-09-15 2014-09-15
US62/050,439 2014-09-15
PCT/US2015/049961 WO2016044150A1 (en) 2014-09-15 2015-09-14 VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION

Publications (1)

Publication Number Publication Date
CA2961208A1 true CA2961208A1 (en) 2016-03-24

Family

ID=54200096

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2961208A Abandoned CA2961208A1 (en) 2014-09-15 2015-09-14 Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression

Country Status (11)

Country Link
US (6) US20160074340A1 (enExample)
EP (2) EP3193853A1 (enExample)
JP (2) JP2017528483A (enExample)
KR (1) KR20170054470A (enExample)
CN (1) CN107208133A (enExample)
AU (1) AU2015318123A1 (enExample)
CA (1) CA2961208A1 (enExample)
IL (2) IL251068A0 (enExample)
MA (1) MA40620A (enExample)
MX (1) MX2017003366A (enExample)
WO (1) WO2016044150A1 (enExample)

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EP3193853A1 (en) 2014-09-15 2017-07-26 Janssen Pharmaceutica NV VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION
US20160338977A1 (en) * 2015-05-20 2016-11-24 Janssen Pharmaceutica Nv Methods and kits for treating depression
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WO2018079693A1 (ja) * 2016-10-27 2018-05-03 国立大学法人 千葉大学 （ｓ）－ノルケタミンおよびその塩の医薬品としての応用
US20200009081A1 (en) 2017-09-13 2020-01-09 Janssen Pharmaceutica N.V. Delivery Of Esketamine For The Treatment Of Depression
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CA3103440A1 (en) 2018-06-27 2020-01-02 Clexio Biosciences Ltd. Method of treating major depressive disorder
WO2020070706A1 (en) 2018-10-05 2020-04-09 Clexio Biosciences Ltd. Dosage regime of esketamine for treating major depressive disorder
WO2020075134A1 (en) 2018-10-11 2020-04-16 Clexio Biosciences Ltd. Esketamine for use in treating major depressive disorder
EP3934632A4 (en) * 2019-03-05 2022-11-23 Janssen Pharmaceuticals, Inc. Esketamine for the treatment of depression
KR20220045929A (ko) * 2019-04-09 2022-04-13 비스타젠 쎄라퓨틱스, 인크. 신경 질환의 치료 반응과 관련된 유전적 변이
EP3923920A4 (en) * 2019-08-05 2022-11-23 The Ketamine Research Foundation KETAMINE FOR THE TREATMENT OF SYMPTOMS AND DISORDERS AFTER CHILDREN
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WO2021137147A1 (en) 2019-12-30 2021-07-08 Clexio Biosciences Ltd. Dosage regime with esketamine for treating major depressive disorder
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PH12022551856A1 (en) * 2020-01-22 2024-01-03 Seelos Therapeutics Inc Reducing side effects of nmda antagonists
US20220175701A1 (en) * 2020-12-08 2022-06-09 Therapeutic Solutions International, Inc. Treatment of major depressive disorder and suicidal ideations through stimulation of hippocampal neurogenesis utilizing plant-based approaches
JP2024511169A (ja) * 2021-03-26 2024-03-12 ピーエックス・アイエヌジー，エルエルシー 運動誘発性精神疲労を低減するためのパラキサンチンの使用
EP4494634A4 (en) * 2022-04-26 2025-07-23 Yichang Humanwell Pharmaceutical Co Ltd LIQUID PREPARATION OF ESKETAMINE AND ITS USE
CN115418398B (zh) * 2022-08-30 2025-02-18 广州医科大学附属脑科医院 一组用于预测氯胺酮治疗难治性抑郁症的疗效的标志物及其应用
JP2026501567A (ja) * 2022-12-28 2026-01-16 パーセプション ニューロサイエンス，インコーポレイティド Ｒ－ケタミンの投与方法

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Also Published As

Publication number Publication date
MX2017003366A (es) 2018-02-01
EP3193853A1 (en) 2017-07-26
JP2021054829A (ja) 2021-04-08
IL251068A0 (en) 2017-04-30
EP3725307A1 (en) 2020-10-21
CN107208133A (zh) 2017-09-26
US11173134B2 (en) 2021-11-16
WO2016044150A1 (en) 2016-03-24
IL279119A (en) 2021-01-31
US11311500B2 (en) 2022-04-26
MA40620A (fr) 2016-03-24
US20250255835A1 (en) 2025-08-14
US20210106545A1 (en) 2021-04-15
JP2017528483A (ja) 2017-09-28
US20160074340A1 (en) 2016-03-17
US20230089113A1 (en) 2023-03-23
US10869844B2 (en) 2020-12-22
US20210308076A1 (en) 2021-10-07
AU2015318123A1 (en) 2017-03-30
KR20170054470A (ko) 2017-05-17
US20200246279A1 (en) 2020-08-06

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