CA2950132C - Preparations de materiaux polymeres a mediation par l'eau - Google Patents

Preparations de materiaux polymeres a mediation par l'eau Download PDF

Info

Publication number
CA2950132C
CA2950132C CA2950132A CA2950132A CA2950132C CA 2950132 C CA2950132 C CA 2950132C CA 2950132 A CA2950132 A CA 2950132A CA 2950132 A CA2950132 A CA 2950132A CA 2950132 C CA2950132 C CA 2950132C
Authority
CA
Canada
Prior art keywords
vessel
acid
water
monomer
polymeric material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2950132A
Other languages
English (en)
Other versions
CA2950132A1 (fr
Inventor
Charles Brendan NICHOLSON
Jeremy J. Harris
Peter D. Gabriele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Secant Group LLC
Original Assignee
Secant Group LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Secant Group LLC filed Critical Secant Group LLC
Publication of CA2950132A1 publication Critical patent/CA2950132A1/fr
Application granted granted Critical
Publication of CA2950132C publication Critical patent/CA2950132C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D167/00—Coating compositions based on polyesters obtained by reactions forming a carboxylic ester link in the main chain; Coating compositions based on derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/81—Preparation processes using solvents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2230/00—Compositions for preparing biodegradable polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Polyamides (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Biological Depolymerization Polymers (AREA)

Abstract

L'invention concerne un procédé de préparation d'un matériau polymère par l'intermédiaire d'un procédé de polymérisation à médiation par l'eau qui consiste à combiner un monomère alcool et une solution aqueuse dans une cuve, à ajouter un monomère acide dans la cuve, à éliminer l'eau de la cuve et à produire le matériau polymère à partir de la cuve, le matériau polymère comprenant un polyester du monomère alcool et du monomère acide. Les procédés décrits dans la présente description sont particulièrement adaptés à la polymérisation d'un poly(sébaçate de glycérol).
CA2950132A 2014-05-30 2015-05-29 Preparations de materiaux polymeres a mediation par l'eau Active CA2950132C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462005299P 2014-05-30 2014-05-30
US62/005,299 2014-05-30
US201562138796P 2015-03-26 2015-03-26
US62/138,796 2015-03-26
PCT/US2015/033270 WO2015184313A1 (fr) 2014-05-30 2015-05-29 Préparations de matériaux polymères à médiation par l'eau

Publications (2)

Publication Number Publication Date
CA2950132A1 CA2950132A1 (fr) 2015-12-03
CA2950132C true CA2950132C (fr) 2022-01-18

Family

ID=53404904

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2950132A Active CA2950132C (fr) 2014-05-30 2015-05-29 Preparations de materiaux polymeres a mediation par l'eau

Country Status (6)

Country Link
US (3) US9359472B2 (fr)
EP (1) EP3149067B1 (fr)
JP (1) JP6538087B2 (fr)
CA (1) CA2950132C (fr)
IL (1) IL249251B (fr)
WO (1) WO2015184313A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102181336B1 (ko) 2013-06-13 2020-11-24 오르제네시스 엘티디. 세포 집단, 이의 전환분화 방법 및 이용 방법
CA2950132C (fr) * 2014-05-30 2022-01-18 The Secant Group, Llc Preparations de materiaux polymeres a mediation par l'eau
EP3180041B1 (fr) 2014-08-14 2022-04-20 The Secant Group, LLC Composition, procédés et dispositifs utiles pour la fabrication d'articles implantables
MA41296A (fr) 2014-12-30 2017-11-07 Orgenesis Ltd Procédés de transdifférenciation et procédés d'utilisation de ceux-ci
JP6882312B2 (ja) 2016-02-25 2021-06-02 ザ・セカント・グループ・エルエルシー ポリ（グリセロールセバケート）フィラーを含む複合材料
CA3033989A1 (fr) 2016-08-18 2018-02-22 The Secant Group, Llc Composition, articles et procedes de soin des plaies
EP3284583B1 (fr) * 2016-08-18 2019-02-20 Cubicure GmbH Procede et dispositif de fabrication generative par lithographie de corps de formage tridimensionnels
JP7216007B2 (ja) * 2017-03-31 2023-01-31 ザ・セカント・グループ・エルエルシー 硬化した生分解性微粒子及び足場材料、並びにそれらの製造方法及び使用方法
SG11201911256UA (en) 2017-05-08 2020-01-30 Orgenesis Ltd Transdifferentiated cell populations and methods of use thereof
WO2018223007A1 (fr) 2017-06-02 2018-12-06 The Secant Group, Llc Élastomère biodégradable dopé pour applications de fond de trou
WO2019014349A1 (fr) 2017-07-11 2019-01-17 The Secant Group, Llc Copolymères de poly (sébacate de glycérol)-inhibiteur d'interleukine et leurs procédés de fabrication et d'utilisation
WO2019050975A1 (fr) * 2017-09-05 2019-03-14 Maguire Abbey, Llc Procédé, compositions, et articles pour améliorer la lubrification d'articulation
JP7300447B2 (ja) * 2017-11-02 2023-06-29 ザ・セカント・グループ・エルエルシー ポリ（グリセロールセバケート）／アルギネート連続繊維を製造する方法及びシステム、並びに連続ポリ（グリセロールセバケート）繊維を含むヤーン
PL234639B1 (pl) * 2018-01-05 2020-03-31 Politechnika Warszawska Sposób wytwarzania prepolimeru poli(sebacynianu glicerolu)
WO2019143834A1 (fr) 2018-01-17 2019-07-25 The Secant Group, Llc Polymère biodégradable modulant le ph et support de culture cellulaire enrichi en poly (sébacate de glycérol)
KR20200110657A (ko) 2018-01-17 2020-09-24 더 시컨트 그룹, 엘엘씨 강화된 생물학적 봉쇄 물질 및 강화된 생물학적 봉쇄 인클로저
US10918729B2 (en) 2018-01-31 2021-02-16 The Secant Group, Llc Osteostimulating elastomeric bone filling compositions
WO2019165082A1 (fr) 2018-02-21 2019-08-29 The Secant Group, Llc Compositions dermo-cosmétiques comprenant du glycérol-sébacate
US10918764B2 (en) 2018-08-21 2021-02-16 The Secant Group, Llc Tunable, controlled-release, urethane-containing elastomers and processes of forming the same
JP7417886B2 (ja) 2019-02-25 2024-01-19 互応化学工業株式会社 有機－無機複合材料の製造方法及び有機－無機複合成形物の製造方法
CR20220081A (es) 2019-08-23 2022-07-14 Sorse Tech Corporation Administración de cannabinoides no inmunogénicos biorremediadores
EP4117651A1 (fr) 2020-03-09 2023-01-18 DePuy Synthes Products, Inc. Compositions bactéricides de débridement pour infections de site chirurgical et cicatrisation de plaie chronique
WO2021207223A1 (fr) 2020-04-06 2021-10-14 The Secant Group, Llc Systèmes de (méth)acrylation de polyester utilisant de l'eau
US11939444B2 (en) * 2020-04-09 2024-03-26 The Secant Group, Llc Modified polymer film surfaces for single-use bioreactor bags and biocontainment and methods of forming same
EP4135687A4 (fr) * 2020-04-17 2024-04-17 Univ Connecticut Polycannabinoïdes, composés, compositions et procédés d'utilisation
JP2023536456A (ja) 2020-07-29 2023-08-25 ザ・セカント・グループ・エルエルシー 架橋ポリ（セバシン酸グリセロール）を含む構造を含む形状誘導型制御放出および保持
US20220211904A1 (en) 2021-01-06 2022-07-07 The Secant Group, Llc Poly(glycerol sebacate) urethane elastomeric leaflet for heart valve replacement
WO2022256502A1 (fr) 2021-06-04 2022-12-08 The Secant Group Llc Compositions de cryoconservation et procédés comprenant des composants d'ester de glycérol
US20230126744A1 (en) 2021-10-25 2023-04-27 The Secant Group, Llc. Polymeric delivery systems
FR3130508A1 (fr) * 2021-12-16 2023-06-23 Compagnie Generale Des Etablissements Michelin Dispositifs contenant des ingrédients actifs vis-à-vis des plantes appliqués sur le sol ou les parties aériennes des plantes
US20230265249A1 (en) 2022-02-24 2023-08-24 The Secant Group, Llc Urethane-crosslinked polymeric microparticles and processes of manufacturing the same
US20230330308A1 (en) 2022-04-11 2023-10-19 The Secant Group, Llc Articles, compositions, and methods for sutureless implants

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4664978A (en) * 1985-03-25 1987-05-12 The Dow Chemical Company Methods of modifying polymeric surfaces and articles produced thereby
US4632964A (en) 1985-03-28 1986-12-30 E. I. Du Pont De Nemours And Company Flexible finishes from branched aliphatic polyester urethanes and a melamine crosslinker
US5401796A (en) * 1993-04-02 1995-03-28 Mitsui Toatsu Chemicals, Inc. Aliphatic polyester and preparation process thereof
US6017566A (en) 1997-10-20 2000-01-25 Wm. Wrigley Jr. Company Gum base and chewing gum containing edible polyesters and method for manufacture
IT1307022B1 (it) * 1999-03-15 2001-10-23 Novamont Spa Processo semplificato per l'ottenimento di poliesteri alifaticibiodegradabili.
US6444782B1 (en) 1999-04-26 2002-09-03 Eastman Chemical Company Process for making pre-gels for a cross-linked branched polyester
US6429278B1 (en) * 2001-01-22 2002-08-06 Eastman Chemical Company Process for manufacture of polyesters based on 1,4-cyclohexanedimethanol and isophthalic acid
US7722894B2 (en) 2001-10-22 2010-05-25 Massachusetts Institute Of Technology Biodegradable polymer
US7645504B1 (en) * 2003-06-26 2010-01-12 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophobic and hydrophilic polymers
US20060009839A1 (en) 2004-07-12 2006-01-12 Scimed Life Systems, Inc. Composite vascular graft including bioactive agent coating and biodegradable sheath
US20060276875A1 (en) 2005-05-27 2006-12-07 Stinson Jonathan S Medical devices
AU2008275009A1 (en) 2007-07-11 2009-01-15 Georgia Tech Research Corporation Selectively-releasable adhesives
AU2008326454A1 (en) * 2007-11-19 2009-05-28 Massachusetts Institute Of Technology Adhesive articles
US20110038910A1 (en) * 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
US8716410B2 (en) 2009-11-13 2014-05-06 Nanyang Technological University Biodegradable thermoplastic elastomers
EP2838607A4 (fr) 2012-04-12 2015-12-30 Univ Wake Forest Health Sciences Modèle de conduit pour remplacement du nerf périphérique
CA2950132C (fr) * 2014-05-30 2022-01-18 The Secant Group, Llc Preparations de materiaux polymeres a mediation par l'eau
US9352070B2 (en) 2014-07-22 2016-05-31 Cormatrix Cardiovascular, Inc. Tissue prostheses for repairing, reconstructing and replacing damaged or diseased biological structures and associated tissue

Also Published As

Publication number Publication date
JP6538087B2 (ja) 2019-07-03
EP3149067A1 (fr) 2017-04-05
US20190270909A1 (en) 2019-09-05
WO2015184313A1 (fr) 2015-12-03
IL249251B (en) 2021-05-31
CA2950132A1 (fr) 2015-12-03
US20160251540A1 (en) 2016-09-01
US20150344618A1 (en) 2015-12-03
IL249251A0 (en) 2017-02-28
US9359472B2 (en) 2016-06-07
EP3149067B1 (fr) 2021-03-17
US10329448B2 (en) 2019-06-25
JP2017516901A (ja) 2017-06-22

Similar Documents

Publication Publication Date Title
CA2950132C (fr) Preparations de materiaux polymeres a mediation par l'eau
US5434241A (en) Biodegradable poly(lactic acid)s having improved physical properties and process for their preparation
KR100665672B1 (ko) 새로운 온도 및 ｐＨ 민감성 블록 공중합체 및 이를 이용한고분자 하이드로겔
JP3198110B2 (ja) オキシカルボン酸及びポリカルボン酸から得られるポリマー
DE60316115T2 (de) Dl-lactid-e-caprolacton copolymere
EP2498835B1 (fr) Elastomères thermoplastiques biodégradables
KR20080032194A (ko) 흡수성 폴리에테르 에스테르 및 의료용 임플란트를제조하기 위한 이의 용도
JP2008274267A (ja) ゲル強度に優れた温度及びｐＨ敏感性ブロック共重合体及びその製造方法、並びにそれを用いた薬物伝達体
EA012598B1 (ru) Сверхразветвленные полимеры, содержащие их композиции, способ их получения и их применение
CN112469763B (zh) 耐高温和耐老化的聚乙交酯共聚物及其组成
KR101456343B1 (ko) 하나 이상의 시클릭 단량체로부터 중합체를 제조하는 방법
DK2225180T3 (en) NON-TOXIC POLYSILOXAN MATERIAL FOR MANUFACTURING BIOLOGICALLY RESORABLE AND / OR BIOACTIVE POLYSILOXAN MATERIALS
EP2656864B1 (fr) Particules biodégradables pour un traitement médical et un matériel d'embolisation vasculaire
Gautrot et al. High molecular weight bile acid and ricinoleic acid-based copolyesters via entropy-driven ring-opening metathesis polymerisation
EP2084229B1 (fr) Copolymères absorbables de poly(éthoxyéthylène diglycolate) et de glycolide
Adamus et al. Bioactive oligomers from natural polyhydroxyalkanoates and their synthetic analogues
KR20190095513A (ko) 고분자량의 생분해성 폴리머 제조 방법
US11618980B2 (en) Surface-functionalised polymeric object and method of its production
KR0134938B1 (ko) 생분해성 고분자 필름 및 그의 제조 방법
JP6336860B2 (ja) 高分子材料
KR101544788B1 (ko) 곁사슬 또는 말단에 다양한 관능기가 도입된 생체적합성 폴리에스터 블록 공중합체 및 이의 제조 방법
Ilia et al. TAILORED STAR-SHAPE BIODEGRADABLE POLY (LACTIC ACID)
TW202122479A (zh) 聚醯胺發泡成形體的製造方法
WO2016133461A9 (fr) Synthèse de poly[(r)-3-hydroxybutyrate] multibras et de ses dérivés

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20200403