CA2912151C - Method for producing a plurality of measurement regions on a chip, and chip with measurement regions - Google Patents

Method for producing a plurality of measurement regions on a chip, and chip with measurement regions Download PDF

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Publication number
CA2912151C
CA2912151C CA2912151A CA2912151A CA2912151C CA 2912151 C CA2912151 C CA 2912151C CA 2912151 A CA2912151 A CA 2912151A CA 2912151 A CA2912151 A CA 2912151A CA 2912151 C CA2912151 C CA 2912151C
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CA
Canada
Prior art keywords
chip
measurement regions
regions
measurement
hydrophobic
Prior art date
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Active
Application number
CA2912151A
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English (en)
French (fr)
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CA2912151A1 (en
Inventor
Markus Schieber
Heinz SCHOEDER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Vetmedica GmbH
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Boehringer Ingelheim Vetmedica GmbH
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Filing date
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Publication of CA2912151A1 publication Critical patent/CA2912151A1/en
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Classifications

    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10P—GENERIC PROCESSES OR APPARATUS FOR THE MANUFACTURE OR TREATMENT OF DEVICES COVERED BY CLASS H10
    • H10P74/00—Testing or measuring during manufacture or treatment of wafers, substrates or devices
    • H10P74/27—Structural arrangements therefor
    • H10P74/273—Interconnections for measuring or testing, e.g. probe pads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5088—Rigid containers without fluid transport within confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10D—INORGANIC ELECTRIC SEMICONDUCTOR DEVICES
    • H10D64/00—Electrodes of devices having potential barriers
    • H10D64/01—Manufacture or treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B01J2219/00317—Microwell devices, i.e. having large numbers of wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614—Delimitation of the attachment areas
    • B01J2219/00617—Delimitation of the attachment areas by chemical means
    • B01J2219/00619—Delimitation of the attachment areas by chemical means using hydrophilic or hydrophobic regions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00635—Introduction of reactive groups to the surface by reactive plasma treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2912151A 2013-05-30 2014-05-30 Method for producing a plurality of measurement regions on a chip, and chip with measurement regions Active CA2912151C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102013210138.4 2013-05-30
DE102013210138.4A DE102013210138A1 (de) 2013-05-30 2013-05-30 Verfahren zum Erzeugen einer Vielzahl von Messbereichen auf einem Chip sowie Chip mit Messbereichen
PCT/EP2014/001462 WO2014191114A2 (de) 2013-05-30 2014-05-30 Verfahren zum erzeugen einer vielzahl von messbereichen auf einem chip sowie chip mit messbereichen

Publications (2)

Publication Number Publication Date
CA2912151A1 CA2912151A1 (en) 2014-12-04
CA2912151C true CA2912151C (en) 2022-07-19

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2912151A Active CA2912151C (en) 2013-05-30 2014-05-30 Method for producing a plurality of measurement regions on a chip, and chip with measurement regions

Country Status (12)

Country Link
US (2) US9735072B2 (https=)
EP (1) EP3004858B1 (https=)
JP (2) JP6453316B2 (https=)
KR (1) KR20160015296A (https=)
CN (2) CN110215940A (https=)
BR (2) BR122017011406B1 (https=)
CA (1) CA2912151C (https=)
DE (1) DE102013210138A1 (https=)
DK (1) DK3004858T3 (https=)
ES (1) ES2687949T3 (https=)
PL (1) PL3004858T3 (https=)
WO (1) WO2014191114A2 (https=)

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CN105908128B (zh) * 2016-04-21 2018-11-06 厦门建霖健康家居股份有限公司 一种光感应制备仿生疏水层的表面处理方法
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CN109706066B (zh) * 2018-12-29 2022-08-26 赛纳生物科技(北京)有限公司 基因测序芯片微坑表面修饰方法
CN109813791B (zh) * 2019-01-02 2020-09-18 北京科技大学 一种基于微柱阵列的微液滴高通量电化学传感器
TWI873119B (zh) * 2019-01-29 2025-02-21 美商伊路米納有限公司 流通槽及製備其之方法
CN110174454A (zh) * 2019-06-18 2019-08-27 北京科技大学 一种微柱高通量的电化学传感器及其制备方法
CN113138186A (zh) * 2021-05-27 2021-07-20 福建师范大学 一种超疏水自动定位sers光谱检测平台及其制备方法和应用
CN114686992A (zh) * 2022-04-22 2022-07-01 赛润(上海)医学科技有限公司 亲疏水选择性修饰的高密度生物芯片制备方法及生物芯片
CN117153713B (zh) * 2023-10-25 2024-02-02 江苏惠达电子科技有限责任公司 频率元器件残留污染物的检测方法、系统和设备控制方法

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Also Published As

Publication number Publication date
JP2016530484A (ja) 2016-09-29
US20160126151A1 (en) 2016-05-05
CA2912151A1 (en) 2014-12-04
DE102013210138A1 (de) 2014-12-04
JP2019070657A (ja) 2019-05-09
CN110215940A (zh) 2019-09-10
CN105408739B (zh) 2019-06-11
PL3004858T3 (pl) 2018-11-30
BR122017011406A2 (pt) 2019-09-03
JP6453316B2 (ja) 2019-01-16
BR122017011406B1 (pt) 2022-03-03
WO2014191114A2 (de) 2014-12-04
WO2014191114A3 (de) 2015-01-22
EP3004858A2 (de) 2016-04-13
BR112015029517A2 (pt) 2017-07-25
EP3004858B1 (de) 2018-07-04
US20170301593A1 (en) 2017-10-19
KR20160015296A (ko) 2016-02-12
JP6759314B2 (ja) 2020-09-23
CN105408739A (zh) 2016-03-16
BR112015029517B1 (pt) 2020-12-01
ES2687949T3 (es) 2018-10-30
DK3004858T3 (en) 2018-09-17
US9735072B2 (en) 2017-08-15
US10381277B2 (en) 2019-08-13

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