CA2893778A1 - N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2h)-carboxylate derivatives - Google Patents

N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2h)-carboxylate derivatives Download PDF

Info

Publication number
CA2893778A1
CA2893778A1 CA2893778A CA2893778A CA2893778A1 CA 2893778 A1 CA2893778 A1 CA 2893778A1 CA 2893778 A CA2893778 A CA 2893778A CA 2893778 A CA2893778 A CA 2893778A CA 2893778 A1 CA2893778 A1 CA 2893778A1
Authority
CA
Canada
Prior art keywords
plant
compounds
methyl
formula
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2893778A
Other languages
English (en)
French (fr)
Inventor
Beth Lorsbach
W. John Owen
Chenglin Yao
Lindsay Stelzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adama Makhteshim Ltd
Original Assignee
Dow AgroSciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow AgroSciences LLC filed Critical Dow AgroSciences LLC
Publication of CA2893778A1 publication Critical patent/CA2893778A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/22—O-Aryl or S-Aryl esters thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dentistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CA2893778A 2012-12-28 2013-12-23 N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2h)-carboxylate derivatives Abandoned CA2893778A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261747086P 2012-12-28 2012-12-28
US61/747,086 2012-12-28
PCT/US2013/077540 WO2014105844A1 (en) 2012-12-28 2013-12-23 N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2h)-carboxylate derivatives

Publications (1)

Publication Number Publication Date
CA2893778A1 true CA2893778A1 (en) 2014-07-03

Family

ID=51022033

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2893778A Abandoned CA2893778A1 (en) 2012-12-28 2013-12-23 N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2h)-carboxylate derivatives

Country Status (18)

Country Link
US (2) US9622474B2 (enExample)
EP (1) EP2938194B1 (enExample)
JP (1) JP6324994B2 (enExample)
KR (1) KR20150103096A (enExample)
CN (2) CN110003118A (enExample)
AU (1) AU2013370493B2 (enExample)
BR (1) BR102013033709B1 (enExample)
CA (1) CA2893778A1 (enExample)
CR (1) CR20150382A (enExample)
DK (1) DK2938194T3 (enExample)
EC (1) ECSP15032859A (enExample)
HU (1) HUE047711T2 (enExample)
IL (1) IL239561B (enExample)
MX (1) MX2015008441A (enExample)
PL (1) PL2938194T3 (enExample)
RU (1) RU2638556C2 (enExample)
UA (1) UA115462C2 (enExample)
WO (1) WO2014105844A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6324994B2 (ja) 2012-12-28 2018-05-16 アダマ・マクテシム・リミテッド Ｎ−（置換）−５−フルオロ−４−イミノ−３−メチル−２−オキソ−３，４−ジヒドロピリミジン−１（２ｈ）−カルボキシレート誘導体
EP3689142A1 (en) * 2012-12-28 2020-08-05 Adama Makhteshim Ltd. 1-(substituted-benzoyl)-5-fluoro-4-imino-3-methyl-3,4-dihydropyrimidin-2(1h)-one derivatives
DK2938191T3 (en) 2012-12-28 2018-05-07 Dow Agrosciences Llc SYNERGISTIC FUNGICIDE MIXTURES FOR FERTILIZER IN GRAIN PLANTS
MX2015008444A (es) 2012-12-28 2015-09-23 Dow Agrosciences Llc Derivados de n-(sustituido)-5-flouro-4-imino-3-metil-2-oxo-3,4-dih idropirimidin-1 (2h)-carboximida.
ES2874475T3 (es) 2012-12-31 2021-11-05 Adama Makhteshim Ltd Derivados de la 3,4-dihidropirimidin-2(1h)-ona 3-alquil-5-fluoro-4-iminosustituida como fungicidas
US9532570B2 (en) 2013-12-31 2017-01-03 Adama Makhteshim Ltd. Synergistic fungicidal mixtures comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1H)-one for fungal control in cereals
EA036389B1 (ru) 2013-12-31 2020-11-03 Адама Мактешим Лтд. 5-фтор-4-имино-3-(алкил/замещенный алкил)-1-(арилсульфонил)-3,4-дигидропиримидин-2(1h)-он и способы их получения
EP3255991B1 (en) 2014-12-30 2020-09-30 Dow Agrosciences LLC Picolinamides as fungicides
CN113173838A (zh) 2014-12-30 2021-07-27 美国陶氏益农公司 具有杀真菌活性的吡啶酰胺化合物
AU2015374375B2 (en) 2014-12-30 2019-03-21 Dow Agrosciences Llc Picolinamides with fungicidal activity
JP6742319B2 (ja) 2014-12-30 2020-08-19 ダウ アグロサイエンシィズ エルエルシー 殺真菌活性を有するピコリンアミド化合物
CA2972408A1 (en) 2014-12-30 2016-07-07 Dow Agrosciences Llc Use of picolinamide compounds with fungicidal activity
CR20210270A (es) 2018-11-05 2021-07-20 Adama Makhteshim Ltd Mezclas y composiciones que comprenden 5-fluoro-4-imino-3-metil-1-tosil-3,4-dihidropirimidin-2-ona, y métodos de uso de los mismos
CN114599639A (zh) 2019-09-23 2022-06-07 阿达玛马克西姆有限公司 用于制备5-(氟-4-亚氨基-3-甲基)-1-甲苯磺酰基-3,4-二氢嘧啶-(1h)-酮的方法

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH421973A (de) 1962-05-01 1966-10-15 Hoffmann La Roche Verfahren zur Herstellung eines Cytosin-Derivates
US3309359A (en) 1965-10-22 1967-03-14 Hoffmann La Roche N-mono-acyl-5-fluorocytosine derivatives and process
US3368938A (en) 1966-01-13 1968-02-13 Hoffmann La Roche Controlling fungi with 5-fluorocytosine
US3635977A (en) 1969-11-03 1972-01-18 American Cyanamid Co Certain 6-trifluoromethylcytosines and thiocytosines their synthesis and their use in the synthesis of uracisls and thiouracil
US3868373A (en) 1970-01-27 1975-02-25 Hoffmann La Roche 4-Amino-5-fluoro-2-tri(lower alkyl) silyloxypyrimidines
US4009272A (en) 1971-10-23 1977-02-22 Bayer Aktiengesellschaft Penicillins
CH579057A5 (enExample) 1973-09-07 1976-08-31 Hoffmann La Roche
FR2530636A1 (fr) 1982-07-23 1984-01-27 Rhone Poulenc Agrochimie Nouveaux derives de la tetrahydro-2,3,6,7 5h-thiazolo (3,2-a) pyrimidine, leur preparation et leur utilisation comme herbicides
EP0139613A1 (de) 1983-08-29 1985-05-02 Ciba-Geigy Ag N-(2-Nitrophenyl)-4-aminopyrimidin-Derivate, deren Herstellung und Verwendung
JPS60123486A (ja) 1983-12-09 1985-07-02 Asahi Glass Co Ltd フルオロブラストサイジンｓおよびその製法
US4845081A (en) 1984-10-18 1989-07-04 University Of Florida Aminomethyl derivatives of biologically active substances, and enhanced delivery thereof across topical membranes
EP0332579B1 (de) 1988-03-09 1994-08-10 Ciba-Geigy Ag Mittel zum Schutz von Pflanzen gegen Krankheiten
DE3821711A1 (de) 1988-06-28 1990-02-08 Bayer Ag Thiazolopyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
JP3109012B2 (ja) 1992-06-18 2000-11-13 クミアイ化学工業株式会社 チアゾロ［５，４−ｄ］ピリミジン誘導体及び農園芸用殺菌剤
JP3217191B2 (ja) 1992-07-16 2001-10-09 ビーエーエスエフ アクチェンゲゼルシャフト ヘテロ芳香族化合物およびこれを含有する植物保護剤
CN1105113C (zh) 1995-07-05 2003-04-09 纳幕尔杜邦公司 杀真菌嘧啶酮
KR100213932B1 (ko) 1995-11-02 1999-08-02 김충환 새로운 뉴클레오시드 유도체 및 그 제조방법
TR199801813T2 (xx) 1996-03-11 1998-12-21 Novartis Ag B�cek �ld�r�c� olarak pirimidin-4- on t�revleri.
HRP970239B1 (en) 1997-05-09 2004-04-30 Inst Ru Er Bouekovic Process for the preparation of sulfonyl-pyrimidine derivatives with antitumor activity
GT199900185A (es) 1998-11-06 2001-04-18 Novedosa pirimidin-4-enamina como fungicida.
AU2002212015B2 (en) 2000-10-13 2007-01-25 Shire Canada Inc. Dioxolane analogs for improved inter-cellular delivery
WO2003018051A1 (en) 2001-08-27 2003-03-06 Vic Jira Anti-fungal composition
AU2003274652A1 (en) 2002-10-23 2004-05-13 Obetherapy Biotechnology Compounds, compositions and methods for modulating fat metabolism
EA009517B1 (ru) * 2003-06-27 2008-02-28 Байер Кропсайенс Аг Пиразолопиримидины
EP1731523A4 (en) 2004-04-01 2009-08-12 Takeda Pharmaceutical THIAZOLOPYRIMIDINDERIVAT
US20070249548A1 (en) 2004-09-16 2007-10-25 Gifu University Nucleoside Analog or Salts of the Same
DE112005002218T5 (de) 2004-09-17 2007-08-09 Kabushiki Kaisha Yaskawa Denki, Kitakyushu Motorsteuervorrichtung und Verfahren zum Montieren der Motorsteuervorrichtung
TWI402034B (zh) 2005-07-28 2013-07-21 Dow Agrosciences Llc 具有被層狀液晶覆膜包覆之油球之水包油乳化劑之農用組成物
US20090163567A1 (en) 2005-11-22 2009-06-25 Ishihara Sangyo Kaisha, Ltd Germicide composition for agricultural and gardening applications and method for controlling plant disease
EP1798255A1 (en) 2005-12-14 2007-06-20 de Schrijver, Aster Reactive diluent for one or two component PU foams
US20080004253A1 (en) 2006-06-30 2008-01-03 Bryan James Branstetter Thiazolopyrimidine modulators of TRPV1
US20100029483A1 (en) 2006-10-16 2010-02-04 Rhodia Inc. Agricultural adjuvant compositions, pesticide compositions, and methods for using such compositions
US8093245B2 (en) 2006-12-14 2012-01-10 Lexicon Pharmaceuticals, Inc. 4-amino-1H-pyrimidin-2-one based compounds, compositions comprising them and methods of their use
US20100056468A1 (en) 2007-01-08 2010-03-04 University Health Network Pyrimidine Derivatives As Anticancer Agents
AU2008219166B2 (en) 2007-02-16 2013-05-16 Amgen Inc. Nitrogen-containing heterocyclyl ketones and their use as c-Met inhibitors
BRPI0810821A8 (pt) 2007-04-27 2015-09-15 Asubio Pharma Co Ltd Derivados de anéis aromáticos de seis membros contendo nitrogênio e produtos farmacêuticos contendo os mesmos
DK2252594T3 (en) 2008-01-22 2015-11-23 Dow Agrosciences Llc 4-amino-5-fluoro-pyrimidine derivatives as fungicides
US20100284959A1 (en) 2008-01-23 2010-11-11 Gene Arrest Ltd. Sequence specific double-stranded dna/rna binding compounds and uses thereof
MX2011001091A (es) 2008-08-01 2011-03-15 Dow Agrosciences Llc Uso de 5-fluorocitosina como un fungicida.
EP2326327B1 (en) 2008-09-17 2016-03-23 SRI International Analogs of indole-3-carbinol and their use as agents against infection
SI2389375T1 (sl) 2009-01-23 2015-11-30 Euro-Celtique S.A. Derivati hidroksamske kisline
UA107671C2 (en) 2009-08-07 2015-02-10 Dow Agrosciences Llc N1-substityted-5-fluoro-2-oxopyrimidinone-1(2h)-carboxamide derivatives
UA112284C2 (uk) * 2009-08-07 2016-08-25 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні 5-фторпіримідинону
AU2010279411B2 (en) 2009-08-07 2014-10-23 Adama Makhteshim Ltd. N1-sulfonyl-5-fluoropyrimidinone derivatives
UA106889C2 (uk) 2009-08-07 2014-10-27 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні n1-ацил-5-фторпіримідинону
BR112012002807B1 (pt) * 2009-08-07 2018-07-10 Adama Makhteshim Ltd. Derivados de 5-flúor-2-oxopirimidina-1(2h)- caboxilato, composição e processo para controle e prevenção de ataque fúngico em uma planta de ataque fúngico em uma planta
AU2010303832B2 (en) 2009-10-07 2015-02-12 Dow Agrosciences Llc Synergistic fungicidal composition containing 5-fluorocytosine for fungal control in cereals
HRP20161107T1 (hr) 2010-04-26 2016-12-30 Adama Makhteshim Ltd Derivati n3-supstituiranog-n1-sulfonil-5-fluoropirimidinona
US20120208700A1 (en) 2011-02-11 2012-08-16 Dow Agrosciences Llc Stable agrochemical oil dispersions
WO2012108873A1 (en) 2011-02-11 2012-08-16 Dow Agrosciences Llc Stable agrochemical oil dispersions
AR087549A1 (es) 2011-08-17 2014-04-03 Dow Agrosciences Llc Derivados de 5-fluor-4-imino-3-(sustituido)-3,4-dihidropirimidin-2(1h)ona
WO2013113781A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds i
US9385377B2 (en) 2012-11-07 2016-07-05 Toyota Jidosha Kabushiki Kaisha Method for producing a catalyst for fuel cells
EP3689142A1 (en) 2012-12-28 2020-08-05 Adama Makhteshim Ltd. 1-(substituted-benzoyl)-5-fluoro-4-imino-3-methyl-3,4-dihydropyrimidin-2(1h)-one derivatives
MX2015008444A (es) 2012-12-28 2015-09-23 Dow Agrosciences Llc Derivados de n-(sustituido)-5-flouro-4-imino-3-metil-2-oxo-3,4-dih idropirimidin-1 (2h)-carboximida.
JP6324994B2 (ja) 2012-12-28 2018-05-16 アダマ・マクテシム・リミテッド Ｎ−（置換）−５−フルオロ−４−イミノ−３−メチル−２−オキソ−３，４−ジヒドロピリミジン−１（２ｈ）−カルボキシレート誘導体
ES2874475T3 (es) 2012-12-31 2021-11-05 Adama Makhteshim Ltd Derivados de la 3,4-dihidropirimidin-2(1h)-ona 3-alquil-5-fluoro-4-iminosustituida como fungicidas
EA036389B1 (ru) 2013-12-31 2020-11-03 Адама Мактешим Лтд. 5-фтор-4-имино-3-(алкил/замещенный алкил)-1-(арилсульфонил)-3,4-дигидропиримидин-2(1h)-он и способы их получения
US9532570B2 (en) 2013-12-31 2017-01-03 Adama Makhteshim Ltd. Synergistic fungicidal mixtures comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1H)-one for fungal control in cereals
MA41272A (fr) 2014-12-23 2017-10-31 Adama Makhteshim Ltd 5-fluoro-4-imino-3-(alkyle/alkyle substitué)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one en tant que traitement des semences

Also Published As

Publication number Publication date
US9908855B2 (en) 2018-03-06
IL239561B (en) 2018-01-31
CN110003118A (zh) 2019-07-12
AU2013370493B2 (en) 2017-08-17
EP2938194B1 (en) 2019-11-27
AU2013370493A1 (en) 2015-07-02
CR20150382A (es) 2015-08-21
BR102013033709B1 (pt) 2019-05-14
BR102013033709A2 (pt) 2015-10-06
WO2014105844A1 (en) 2014-07-03
RU2638556C2 (ru) 2017-12-14
EP2938194A1 (en) 2015-11-04
CN104902757A (zh) 2015-09-09
EP2938194A4 (en) 2016-08-31
KR20150103096A (ko) 2015-09-09
IL239561A0 (en) 2015-08-31
RU2015131095A (ru) 2017-02-06
MX2015008441A (es) 2015-09-23
JP6324994B2 (ja) 2018-05-16
JP2016507512A (ja) 2016-03-10
HK1214475A1 (en) 2016-07-29
DK2938194T3 (da) 2020-01-02
UA115462C2 (uk) 2017-11-10
CN104902757B (zh) 2019-01-08
HUE047711T2 (hu) 2020-05-28
US9622474B2 (en) 2017-04-18
PL2938194T3 (pl) 2020-09-21
US20160192653A1 (en) 2016-07-07
US20170204069A1 (en) 2017-07-20
ECSP15032859A (es) 2015-11-30

Similar Documents

Publication Publication Date Title
US9840475B2 (en) N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2H)-carboxamide derivatives
AU2013370470B2 (en) 1-(substituted-benzoyl)-5-fluoro-4-imino-3-methyl-3,4-dihydropyrimidin-2(1H)-one derivatives
CA2797226C (en) N3-substituted-n1-sulfonyl-5-fluoropyrimidinone derivatives
CA2844497C (en) 5-fluoro-4-imino-3-(substituted)-3,4-dihydropyrimidin-2-(1h)one derivatives
US9908855B2 (en) N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2H)-carboxylate derivatives
WO2018045003A1 (en) Picolinamide n-oxide compounds with fungicidal activity
WO2018045012A1 (en) Pyrido-1,3-oxazine-2,4-dione compounds with fungicidal activity
EP3506757A1 (en) Pyrido-1,3-oxazine-2,4-dione compounds with fungicidal activity
AU2012296629B8 (en) 5-fluoro-4-imino-3-(substituted)-3,4-dihydropyrimidin-2-(1H)-one derivatives
HK40034526A (en) 1-(substituted-benzoyl)-5-fluoro-4-imino-3-methyl-3,4-dihydropyrimidin-2(1h)-one derivatives
HK1214475B (en) N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2h)-carboxylate derivatives
HK1216147B (zh) 1-(取代的苯甲酰基)-5-氟-4-亚氨基-3-甲基-3，4-二氢嘧啶-2(1h)-酮衍生物
EP2744334A2 (en) N-(5-fluoro-2((4-methylbenzyl)oxy)pyrimidin-4-yl) benzamide derivatives

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20191224