CA2885105A1 - Magnesium hydroxide carbonate as carrier material in active ingredient-containing preparations - Google Patents
Magnesium hydroxide carbonate as carrier material in active ingredient-containing preparations Download PDFInfo
- Publication number
- CA2885105A1 CA2885105A1 CA2885105A CA2885105A CA2885105A1 CA 2885105 A1 CA2885105 A1 CA 2885105A1 CA 2885105 A CA2885105 A CA 2885105A CA 2885105 A CA2885105 A CA 2885105A CA 2885105 A1 CA2885105 A1 CA 2885105A1
- Authority
- CA
- Canada
- Prior art keywords
- formulation according
- magnesium hydroxide
- sample
- active ingredient
- hydroxide carbonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000004480 active ingredient Substances 0.000 title claims description 83
- OUHCLAKJJGMPSW-UHFFFAOYSA-L magnesium;hydrogen carbonate;hydroxide Chemical compound O.[Mg+2].[O-]C([O-])=O OUHCLAKJJGMPSW-UHFFFAOYSA-L 0.000 title claims description 41
- 238000002360 preparation method Methods 0.000 title claims description 34
- 239000012876 carrier material Substances 0.000 title description 12
- 239000000203 mixture Substances 0.000 claims abstract description 117
- 238000009472 formulation Methods 0.000 claims abstract description 50
- 239000000126 substance Substances 0.000 claims abstract description 27
- 239000007787 solid Substances 0.000 claims abstract description 14
- 239000002245 particle Substances 0.000 claims description 43
- 239000000843 powder Substances 0.000 claims description 28
- 239000003826 tablet Substances 0.000 claims description 27
- 238000000034 method Methods 0.000 claims description 24
- 239000000463 material Substances 0.000 claims description 19
- 238000004519 manufacturing process Methods 0.000 claims description 8
- 230000008569 process Effects 0.000 claims description 8
- 235000010755 mineral Nutrition 0.000 claims description 7
- 239000011707 mineral Substances 0.000 claims description 7
- 239000002775 capsule Substances 0.000 claims description 6
- 239000002537 cosmetic Substances 0.000 claims description 6
- 235000015872 dietary supplement Nutrition 0.000 claims description 6
- 239000000314 lubricant Substances 0.000 claims description 6
- 239000008194 pharmaceutical composition Substances 0.000 claims description 6
- 239000006185 dispersion Substances 0.000 claims description 5
- 239000000975 dye Substances 0.000 claims description 5
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 claims description 5
- 239000000347 magnesium hydroxide Substances 0.000 claims description 5
- 235000012254 magnesium hydroxide Nutrition 0.000 claims description 5
- 229910001862 magnesium hydroxide Inorganic materials 0.000 claims description 5
- 229960000816 magnesium hydroxide Drugs 0.000 claims description 5
- 239000000725 suspension Substances 0.000 claims description 5
- 239000011230 binding agent Substances 0.000 claims description 4
- 235000013305 food Nutrition 0.000 claims description 4
- 239000003054 catalyst Substances 0.000 claims description 3
- 239000003153 chemical reaction reagent Substances 0.000 claims description 3
- 239000006071 cream Substances 0.000 claims description 3
- 239000000032 diagnostic agent Substances 0.000 claims description 3
- 229940039227 diagnostic agent Drugs 0.000 claims description 3
- 230000002500 effect on skin Effects 0.000 claims description 3
- 235000003599 food sweetener Nutrition 0.000 claims description 3
- 239000000417 fungicide Substances 0.000 claims description 3
- 239000004009 herbicide Substances 0.000 claims description 3
- 239000002674 ointment Substances 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 3
- 239000003765 sweetening agent Substances 0.000 claims description 3
- 108090000790 Enzymes Proteins 0.000 claims description 2
- 102000004190 Enzymes Human genes 0.000 claims description 2
- 230000000855 fungicidal effect Effects 0.000 claims description 2
- 244000005700 microbiome Species 0.000 claims description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 96
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 88
- 235000010323 ascorbic acid Nutrition 0.000 description 47
- 239000011668 ascorbic acid Substances 0.000 description 47
- 229960005070 ascorbic acid Drugs 0.000 description 45
- 239000002151 riboflavin Substances 0.000 description 45
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 44
- 235000019192 riboflavin Nutrition 0.000 description 44
- 229960002477 riboflavin Drugs 0.000 description 44
- 238000011068 loading method Methods 0.000 description 34
- 238000002156 mixing Methods 0.000 description 23
- 239000000306 component Substances 0.000 description 20
- 239000000945 filler Substances 0.000 description 13
- 239000002253 acid Substances 0.000 description 12
- 238000009826 distribution Methods 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 230000000875 corresponding effect Effects 0.000 description 11
- -1 for example Substances 0.000 description 11
- 238000007873 sieving Methods 0.000 description 11
- 238000000926 separation method Methods 0.000 description 9
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 239000011521 glass Substances 0.000 description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 229920002678 cellulose Polymers 0.000 description 6
- 239000001913 cellulose Substances 0.000 description 6
- 235000010980 cellulose Nutrition 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 238000000691 measurement method Methods 0.000 description 6
- 239000011148 porous material Substances 0.000 description 6
- 238000012545 processing Methods 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 238000001179 sorption measurement Methods 0.000 description 6
- 150000005846 sugar alcohols Chemical class 0.000 description 6
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 5
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 5
- 229920002472 Starch Polymers 0.000 description 5
- 239000000969 carrier Substances 0.000 description 5
- 239000008101 lactose Substances 0.000 description 5
- 229960001375 lactose Drugs 0.000 description 5
- 239000001095 magnesium carbonate Substances 0.000 description 5
- 239000008107 starch Substances 0.000 description 5
- 235000019698 starch Nutrition 0.000 description 5
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 4
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 4
- 235000019700 dicalcium phosphate Nutrition 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- 229910052757 nitrogen Inorganic materials 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
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- 238000004448 titration Methods 0.000 description 4
- 229940088594 vitamin Drugs 0.000 description 4
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- 235000013343 vitamin Nutrition 0.000 description 4
- 239000011782 vitamin Substances 0.000 description 4
- UAYWVJHJZHQCIE-UHFFFAOYSA-L zinc iodide Chemical compound I[Zn]I UAYWVJHJZHQCIE-UHFFFAOYSA-L 0.000 description 4
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 3
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 3
- 239000008186 active pharmaceutical agent Substances 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 239000002671 adjuvant Substances 0.000 description 3
- 229920013820 alkyl cellulose Polymers 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 229920001577 copolymer Polymers 0.000 description 3
- 238000002425 crystallisation Methods 0.000 description 3
- 239000002552 dosage form Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 238000005469 granulation Methods 0.000 description 3
- 230000003179 granulation Effects 0.000 description 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 description 3
- 239000011630 iodine Substances 0.000 description 3
- 229910052740 iodine Inorganic materials 0.000 description 3
- 239000000546 pharmaceutical excipient Substances 0.000 description 3
- 238000009827 uniform distribution Methods 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
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- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 2
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 2
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- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12006551.1 | 2012-09-18 | ||
| EP12006551 | 2012-09-18 | ||
| EP13000730 | 2013-02-13 | ||
| EP13000730.5 | 2013-02-13 | ||
| PCT/EP2013/002490 WO2014044342A1 (de) | 2012-09-18 | 2013-08-19 | Magnesiumhydroxidcarbonat als trägermaterial in wirkstoffhaltigen zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2885105A1 true CA2885105A1 (en) | 2014-03-27 |
Family
ID=49084960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2885105A Abandoned CA2885105A1 (en) | 2012-09-18 | 2013-08-19 | Magnesium hydroxide carbonate as carrier material in active ingredient-containing preparations |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20150273062A1 (enExample) |
| EP (1) | EP2897645A1 (enExample) |
| JP (1) | JP6244363B2 (enExample) |
| KR (1) | KR20150058427A (enExample) |
| CN (1) | CN104640569A (enExample) |
| BR (1) | BR112015005621A2 (enExample) |
| CA (1) | CA2885105A1 (enExample) |
| IL (1) | IL237741A0 (enExample) |
| WO (1) | WO2014044342A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112812194A (zh) | 2014-12-11 | 2021-05-18 | 信越化学工业株式会社 | 制备烷基纤维素的方法 |
| US10723807B2 (en) | 2017-03-31 | 2020-07-28 | Shin-Etsu Chemical Co., Ltd. | Method for producing hydroxyalkyl alkyl cellulose |
| JP6423481B1 (ja) * | 2017-04-28 | 2018-11-14 | 神島化学工業株式会社 | 炭酸マグネシウム |
| WO2020176028A1 (en) * | 2019-02-25 | 2020-09-03 | Disruptive Materials Ab | Particulate amorphous mesoporous magnesium carbonate material |
| JP7093812B2 (ja) * | 2019-06-27 | 2022-06-30 | Ｄｏｗａエレクトロニクス株式会社 | 銀粉およびその製造方法 |
| KR102483759B1 (ko) * | 2022-01-18 | 2022-12-30 | 박민규 | 필러 조성물의 제조 방법 |
| CN116515343B (zh) * | 2023-05-24 | 2024-08-30 | 江西广源新材料有限公司 | 一种视黄酸/水菱镁复合粉体及其制备方法和应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3242353A1 (de) * | 1982-11-16 | 1984-05-30 | Hoechst Ag, 6230 Frankfurt | Lagerstabile, die wirkstoffe pyrazophos und captafol enthaltende mittel |
| JPH0768121B2 (ja) * | 1987-07-21 | 1995-07-26 | 信越化学工業株式会社 | 固形薬剤のコ−ティング方法 |
| DE3819926A1 (de) * | 1988-06-11 | 1989-12-14 | Gruenau Gmbh Chem Fab | Verfahren zur verbesserung des fliessverhaltens von zum verklumpen neigenden pulvermischungen |
| JPH07114946B2 (ja) * | 1988-10-24 | 1995-12-13 | 株式会社奈良機械製作所 | 難溶性物質の処理方法 |
| JPH04228420A (ja) * | 1990-06-04 | 1992-08-18 | Tokuyama Soda Co Ltd | 塩基性炭酸マグネシウム及びその製造方法 |
| JPH04369375A (ja) * | 1991-06-17 | 1992-12-22 | Matsushita Refrig Co Ltd | 冷蔵庫 |
| JPH05194275A (ja) * | 1991-09-03 | 1993-08-03 | Takeda Chem Ind Ltd | 製剤用組成物、固形製剤および薬物の防臭方法 |
| JP3005883B2 (ja) | 1992-12-28 | 2000-02-07 | 富士化学工業株式会社 | リン酸水素カルシウムの製造方法およびそれを用いた賦形薬 |
| JP2700141B2 (ja) | 1993-09-17 | 1998-01-19 | 富士化学工業株式会社 | リン酸水素カルシウム及びその製法並びにそれを用いた賦形剤 |
| US20020072602A1 (en) * | 2000-07-07 | 2002-06-13 | Claude Singer | Micronized mirtazapine |
| JP3910495B2 (ja) * | 2002-02-13 | 2007-04-25 | 日鉄鉱業株式会社 | 塩基性炭酸マグネシウム及びその製造方法、並びに該塩基性炭酸マグネシウムを含有する組成物又は構造体 |
| JP3910555B2 (ja) * | 2002-09-17 | 2007-04-25 | 日鉄鉱業株式会社 | 中空担体及び機能性粒子、並びにそれらの製造方法 |
| JP4274963B2 (ja) * | 2004-02-04 | 2009-06-10 | 株式会社日本色材工業研究所 | 固形粉末化粧料 |
| IS7724A (is) * | 2005-03-02 | 2006-09-03 | Actavis Group | Samsetning á töflum með hraða sundrun sem innihalda þungt magnesíum karbónat |
| ES2497574T3 (es) * | 2010-02-03 | 2014-09-23 | Merck Patent Gmbh | Hidróxido carbonato de magnesio directamente compresible |
| WO2011095669A1 (en) | 2010-02-04 | 2011-08-11 | Nokia Corporation | Adjusting channel access parameters due to traffic load |
| FR2967913A1 (fr) * | 2010-11-29 | 2012-06-01 | Vetalis | Composition galenique adaptee a l'administration a un animal non-humain, utilisations de celle-ci et methodes associees |
-
2013
- 2013-08-19 WO PCT/EP2013/002490 patent/WO2014044342A1/de not_active Ceased
- 2013-08-19 EP EP13755955.5A patent/EP2897645A1/de not_active Ceased
- 2013-08-19 CN CN201380048184.2A patent/CN104640569A/zh active Pending
- 2013-08-19 BR BR112015005621A patent/BR112015005621A2/pt not_active IP Right Cessation
- 2013-08-19 CA CA2885105A patent/CA2885105A1/en not_active Abandoned
- 2013-08-19 KR KR1020157010004A patent/KR20150058427A/ko not_active Withdrawn
- 2013-08-19 US US14/428,396 patent/US20150273062A1/en not_active Abandoned
- 2013-08-19 JP JP2015532314A patent/JP6244363B2/ja not_active Expired - Fee Related
-
2015
- 2015-03-15 IL IL237741A patent/IL237741A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20150058427A (ko) | 2015-05-28 |
| CN104640569A (zh) | 2015-05-20 |
| JP6244363B2 (ja) | 2017-12-06 |
| WO2014044342A8 (de) | 2015-02-12 |
| EP2897645A1 (de) | 2015-07-29 |
| WO2014044342A1 (de) | 2014-03-27 |
| IL237741A0 (en) | 2015-05-31 |
| BR112015005621A2 (pt) | 2017-07-04 |
| JP2015530393A (ja) | 2015-10-15 |
| US20150273062A1 (en) | 2015-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20190820 |