CN104640569A - 在含活性成分的制剂中用作载体材料的碱式碳酸镁 - Google Patents

在含活性成分的制剂中用作载体材料的碱式碳酸镁 Download PDF

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Publication number
CN104640569A
CN104640569A CN201380048184.2A CN201380048184A CN104640569A CN 104640569 A CN104640569 A CN 104640569A CN 201380048184 A CN201380048184 A CN 201380048184A CN 104640569 A CN104640569 A CN 104640569A
Authority
CN
China
Prior art keywords
preparation
active ingredient
magnesium carbonate
mixture
basic magnesium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380048184.2A
Other languages
English (en)
Chinese (zh)
Inventor
G·摩德摩格
R·奥尼伯内
T·威德尔
D·卢巴达
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of CN104640569A publication Critical patent/CN104640569A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201380048184.2A 2012-09-18 2013-08-19 在含活性成分的制剂中用作载体材料的碱式碳酸镁 Pending CN104640569A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12006551.1 2012-09-18
EP12006551 2012-09-18
EP13000730 2013-02-13
EP13000730.5 2013-02-13
PCT/EP2013/002490 WO2014044342A1 (de) 2012-09-18 2013-08-19 Magnesiumhydroxidcarbonat als trägermaterial in wirkstoffhaltigen zubereitungen

Publications (1)

Publication Number Publication Date
CN104640569A true CN104640569A (zh) 2015-05-20

Family

ID=49084960

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380048184.2A Pending CN104640569A (zh) 2012-09-18 2013-08-19 在含活性成分的制剂中用作载体材料的碱式碳酸镁

Country Status (9)

Country Link
US (1) US20150273062A1 (enExample)
EP (1) EP2897645A1 (enExample)
JP (1) JP6244363B2 (enExample)
KR (1) KR20150058427A (enExample)
CN (1) CN104640569A (enExample)
BR (1) BR112015005621A2 (enExample)
CA (1) CA2885105A1 (enExample)
IL (1) IL237741A0 (enExample)
WO (1) WO2014044342A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110573458A (zh) * 2017-04-28 2019-12-13 神岛化学工业株式会社 碳酸镁
CN113518609A (zh) * 2019-02-25 2021-10-19 破坏性材料运营公司 粒状无定形介孔碳酸镁材料
TWI777182B (zh) * 2019-06-27 2022-09-11 日商同和電子科技有限公司 銀粉及其製造方法
CN116515343A (zh) * 2023-05-24 2023-08-01 江西广源新材料有限公司 一种视黄酸/水菱镁复合粉体及其制备方法和应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112812194A (zh) 2014-12-11 2021-05-18 信越化学工业株式会社 制备烷基纤维素的方法
US10723807B2 (en) 2017-03-31 2020-07-28 Shin-Etsu Chemical Co., Ltd. Method for producing hydroxyalkyl alkyl cellulose
KR102483759B1 (ko) * 2022-01-18 2022-12-30 박민규 필러 조성물의 제조 방법

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0111747A1 (de) * 1982-11-16 1984-06-27 Hoechst Aktiengesellschaft Lagerstabile, die Wirkstoffe Pyrazophos und Captafol enthaltende, Mittel
EP0346705A1 (de) * 1988-06-11 1989-12-20 Chemische Fabrik Grünau GmbH Verfahren zur Verbesserung des Fliessverhaltens von zum Verklumpen neigenden Pulvermischungen
US5240692A (en) * 1991-06-04 1993-08-31 Tokuyama Soda Kabushiki Kaisha Basic magnesium carbonate and process for preparation thereof
US20020072602A1 (en) * 2000-07-07 2002-06-13 Claude Singer Micronized mirtazapine
CN101132764A (zh) * 2005-03-02 2008-02-27 阿克塔维什集团公司 含重质碳酸镁的快速崩解剂型
WO2011095269A2 (de) * 2010-02-03 2011-08-11 Merck Patent Gmbh Direkt verpressbares magnesiumhydroxidcarbonat

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JPH0768121B2 (ja) * 1987-07-21 1995-07-26 信越化学工業株式会社 固形薬剤のコ−ティング方法
JPH07114946B2 (ja) * 1988-10-24 1995-12-13 株式会社奈良機械製作所 難溶性物質の処理方法
JPH04228420A (ja) * 1990-06-04 1992-08-18 Tokuyama Soda Co Ltd 塩基性炭酸マグネシウム及びその製造方法
JPH05194275A (ja) * 1991-09-03 1993-08-03 Takeda Chem Ind Ltd 製剤用組成物、固形製剤および薬物の防臭方法
JP3005883B2 (ja) 1992-12-28 2000-02-07 富士化学工業株式会社 リン酸水素カルシウムの製造方法およびそれを用いた賦形薬
JP2700141B2 (ja) 1993-09-17 1998-01-19 富士化学工業株式会社 リン酸水素カルシウム及びその製法並びにそれを用いた賦形剤
JP3910495B2 (ja) * 2002-02-13 2007-04-25 日鉄鉱業株式会社 塩基性炭酸マグネシウム及びその製造方法、並びに該塩基性炭酸マグネシウムを含有する組成物又は構造体
JP3910555B2 (ja) * 2002-09-17 2007-04-25 日鉄鉱業株式会社 中空担体及び機能性粒子、並びにそれらの製造方法
JP4274963B2 (ja) * 2004-02-04 2009-06-10 株式会社日本色材工業研究所 固形粉末化粧料
WO2011095669A1 (en) 2010-02-04 2011-08-11 Nokia Corporation Adjusting channel access parameters due to traffic load
FR2967913A1 (fr) * 2010-11-29 2012-06-01 Vetalis Composition galenique adaptee a l'administration a un animal non-humain, utilisations de celle-ci et methodes associees

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0111747A1 (de) * 1982-11-16 1984-06-27 Hoechst Aktiengesellschaft Lagerstabile, die Wirkstoffe Pyrazophos und Captafol enthaltende, Mittel
EP0346705A1 (de) * 1988-06-11 1989-12-20 Chemische Fabrik Grünau GmbH Verfahren zur Verbesserung des Fliessverhaltens von zum Verklumpen neigenden Pulvermischungen
US5240692A (en) * 1991-06-04 1993-08-31 Tokuyama Soda Kabushiki Kaisha Basic magnesium carbonate and process for preparation thereof
US20020072602A1 (en) * 2000-07-07 2002-06-13 Claude Singer Micronized mirtazapine
CN101132764A (zh) * 2005-03-02 2008-02-27 阿克塔维什集团公司 含重质碳酸镁的快速崩解剂型
WO2011095269A2 (de) * 2010-02-03 2011-08-11 Merck Patent Gmbh Direkt verpressbares magnesiumhydroxidcarbonat
WO2011095269A3 (de) * 2010-02-03 2012-05-18 Merck Patent Gmbh Direkt verpressbares magnesiumhydroxidcarbonat
US20120301520A1 (en) * 2010-02-03 2012-11-29 Merck Patent Gesellschaft Mit Beschrankter Haftung Directly compressible magnesium hydroxide carbonate

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨晨: "特殊形貌碳酸镁用途、制备及表征", 《无机盐工业》 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110573458A (zh) * 2017-04-28 2019-12-13 神岛化学工业株式会社 碳酸镁
CN110573458B (zh) * 2017-04-28 2022-06-07 神岛化学工业株式会社 碳酸镁
CN113518609A (zh) * 2019-02-25 2021-10-19 破坏性材料运营公司 粒状无定形介孔碳酸镁材料
CN113518609B (zh) * 2019-02-25 2024-04-30 破坏性材料运营公司 粒状无定形介孔碳酸镁材料
TWI777182B (zh) * 2019-06-27 2022-09-11 日商同和電子科技有限公司 銀粉及其製造方法
CN116515343A (zh) * 2023-05-24 2023-08-01 江西广源新材料有限公司 一种视黄酸/水菱镁复合粉体及其制备方法和应用
CN116515343B (zh) * 2023-05-24 2024-08-30 江西广源新材料有限公司 一种视黄酸/水菱镁复合粉体及其制备方法和应用

Also Published As

Publication number Publication date
KR20150058427A (ko) 2015-05-28
JP6244363B2 (ja) 2017-12-06
WO2014044342A8 (de) 2015-02-12
EP2897645A1 (de) 2015-07-29
WO2014044342A1 (de) 2014-03-27
IL237741A0 (en) 2015-05-31
BR112015005621A2 (pt) 2017-07-04
JP2015530393A (ja) 2015-10-15
CA2885105A1 (en) 2014-03-27
US20150273062A1 (en) 2015-10-01

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