CA2875069C - Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent - Google Patents
Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent Download PDFInfo
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- CA2875069C CA2875069C CA2875069A CA2875069A CA2875069C CA 2875069 C CA2875069 C CA 2875069C CA 2875069 A CA2875069 A CA 2875069A CA 2875069 A CA2875069 A CA 2875069A CA 2875069 C CA2875069 C CA 2875069C
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- 230000003040 nociceptive effect Effects 0.000 description 1
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- 239000003002 pH adjusting agent Substances 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 210000001428 peripheral nervous system Anatomy 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- OQUKIQWCVTZJAF-UHFFFAOYSA-N phenol;sulfuric acid Chemical compound OS(O)(=O)=O.OC1=CC=CC=C1 OQUKIQWCVTZJAF-UHFFFAOYSA-N 0.000 description 1
- 208000028591 pheochromocytoma Diseases 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- ONJQDTZCDSESIW-UHFFFAOYSA-N polidocanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO ONJQDTZCDSESIW-UHFFFAOYSA-N 0.000 description 1
- 229960002226 polidocanol Drugs 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000004481 post-translational protein modification Effects 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 201000011461 pre-eclampsia Diseases 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
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- 230000004147 pyrimidine metabolism Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 229960004641 rituximab Drugs 0.000 description 1
- 238000011076 safety test Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
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- 229940000207 selenious acid Drugs 0.000 description 1
- MCAHWIHFGHIESP-UHFFFAOYSA-N selenous acid Chemical compound O[Se](O)=O MCAHWIHFGHIESP-UHFFFAOYSA-N 0.000 description 1
- 239000004017 serum-free culture medium Substances 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
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- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 229960000187 tissue plasminogen activator Drugs 0.000 description 1
- 229960003989 tocilizumab Drugs 0.000 description 1
- 229940044693 topoisomerase inhibitor Drugs 0.000 description 1
- 208000012175 toxemia of pregnancy Diseases 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 239000012581 transferrin Substances 0.000 description 1
- 229960000575 trastuzumab Drugs 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000009834 vaporization Methods 0.000 description 1
- 230000008016 vaporization Effects 0.000 description 1
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- 229960004355 vindesine Drugs 0.000 description 1
- UGGWPQSBPIFKDZ-KOTLKJBCSA-N vindesine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(N)=O)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1N=C1[C]2C=CC=C1 UGGWPQSBPIFKDZ-KOTLKJBCSA-N 0.000 description 1
- 229960002066 vinorelbine Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/366—Thrombomodulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/7455—Thrombomodulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012125316 | 2012-05-31 | ||
| JP2012-125316 | 2012-05-31 | ||
| PCT/JP2013/063743 WO2013179910A1 (ja) | 2012-05-31 | 2013-05-17 | 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2875069A1 CA2875069A1 (en) | 2013-12-05 |
| CA2875069C true CA2875069C (en) | 2018-01-02 |
Family
ID=49673113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2875069A Active CA2875069C (en) | 2012-05-31 | 2013-05-17 | Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10709767B2 (en:Method) |
| EP (1) | EP2857037B1 (en:Method) |
| JP (3) | JP6124417B2 (en:Method) |
| KR (1) | KR101672114B1 (en:Method) |
| CN (1) | CN104394885B (en:Method) |
| AU (1) | AU2013268725B2 (en:Method) |
| BR (1) | BR112014028852A2 (en:Method) |
| CA (1) | CA2875069C (en:Method) |
| DK (1) | DK2857037T3 (en:Method) |
| ES (1) | ES2743767T3 (en:Method) |
| HU (1) | HUE045997T2 (en:Method) |
| IL (1) | IL235984B (en:Method) |
| IN (1) | IN2014DN10075A (en:Method) |
| MX (1) | MX364934B (en:Method) |
| NZ (1) | NZ702242A (en:Method) |
| PL (1) | PL2857037T3 (en:Method) |
| PT (1) | PT2857037T (en:Method) |
| RU (1) | RU2595857C2 (en:Method) |
| WO (1) | WO2013179910A1 (en:Method) |
| ZA (1) | ZA201408769B (en:Method) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN2014DN10075A (en:Method) | 2012-05-31 | 2015-08-21 | Univ Kinki | |
| JP6325036B2 (ja) * | 2016-08-19 | 2018-05-16 | 株式会社明治 | 抗がん剤に起因する末梢神経障害を改善するための組成物 |
| WO2018181860A1 (ja) * | 2017-03-31 | 2018-10-04 | 東レ株式会社 | 末梢神経障害の治療剤又は予防剤 |
| WO2019123144A1 (en) * | 2017-12-19 | 2019-06-27 | Synergia Life Sciences Pvt. Ltd. | Vitamin k2 compositions for the treatment of drug induced neuropathy |
| US11497795B2 (en) * | 2018-09-28 | 2022-11-15 | Asahi Kasei Pharma Corporation | Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent |
| MX2021003288A (es) * | 2018-09-28 | 2021-05-13 | Asahi Kasei Pharma Corp | Medicacion para aliviar los sintomas de la neuropatia periferica causada por farmacos anticancerigenos y/o suprimir el inicio de la neuropatia periferica. |
| RU2707954C1 (ru) * | 2019-01-24 | 2019-12-02 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ лечения онкологической боли |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0312598B1 (en) | 1987-01-08 | 1999-05-26 | Asahi Kasei Kogyo Kabushiki Kaisha | Peptide functioning to accelerate activation of protein c with thrombin |
| JP2738428B2 (ja) | 1987-01-08 | 1998-04-08 | 旭化成工業株式会社 | トロンビンによるプロテインｃの活性化を促進する作用を有するペプチド |
| DE3876124T2 (de) | 1987-04-01 | 1993-05-06 | Mitsubishi Gas Chemical Co | Immunoassay fuer thrombomodulin. |
| DK299087D0 (da) | 1987-06-12 | 1987-06-12 | Novo Industri As | Proteins and derivatives thereof |
| JPS6445398A (en) | 1987-08-13 | 1989-02-17 | Kowa Co | Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody |
| JPH0720997B2 (ja) | 1988-08-29 | 1995-03-08 | 興和株式会社 | 新規なトロンビン結合性物質及びその製法 |
| JPH02255699A (ja) | 1989-03-28 | 1990-10-16 | Asahi Chem Ind Co Ltd | 新規血液抗凝固物質及びその製法 |
| CA2065409C (en) | 1990-06-27 | 2002-05-14 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant polypeptides |
| JPH05213998A (ja) | 1990-08-03 | 1993-08-24 | Asahi Chem Ind Co Ltd | 新規なポリペプチド及びこれを有効成分とする 医薬組成物 |
| US5571786A (en) | 1990-08-16 | 1996-11-05 | Immuno Aktiengesellschaft | Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation |
| JPH05310787A (ja) | 1992-05-01 | 1993-11-22 | Asahi Chem Ind Co Ltd | 新規なポリペプチド |
| JPH06205692A (ja) | 1993-01-08 | 1994-07-26 | Asahi Chem Ind Co Ltd | 新規な抗ヒトトロンボモジュリンモノクロ−ナル抗体およびその抗体を用いたヒトトロンボモジュリンの高感度測定方法 |
| EP0685994B1 (en) | 1993-02-25 | 2007-03-21 | Abbott Laboratories | Multipurpose reagent system for rapid lysis of whole blood samples |
| JP3007785B2 (ja) | 1993-03-16 | 2000-02-07 | 旭化成工業株式会社 | トロンボモジュリン組成物およびその変性防止方法 |
| JPH083065A (ja) | 1994-04-20 | 1996-01-09 | Asahi Chem Ind Co Ltd | 肝臓障害に対する治療剤 |
| DE69534016T2 (de) | 1994-04-20 | 2006-03-23 | Asahi Kasei Pharma Corp. | Verwendung von thrombomodulin gegen lebererkrankungen |
| US5916874A (en) | 1994-04-20 | 1999-06-29 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for treating liver injury |
| JP2824392B2 (ja) | 1994-05-31 | 1998-11-11 | 旭化成工業株式会社 | トロンビンによるプロテインｃの活性化を促進する作用を有するペプチドを含有する培養上澄液 |
| US5827832A (en) | 1995-03-06 | 1998-10-27 | Interneuron Pharmaceuticals, Inc. | Method of protecting brain tissue from cerebral infarction subsequent to ischemia |
| CA2213000A1 (en) | 1995-03-06 | 1996-09-12 | Interneuron Pharmaceuticals, Inc. | Reduction of infarct volume using citicoline |
| US5872108A (en) | 1995-03-06 | 1999-02-16 | Interneuron Pharmaceuticals, Inc. | Reduction of infarct volume using citicoline |
| JP3789147B2 (ja) | 1995-04-11 | 2006-06-21 | 旭化成ファーマ株式会社 | 脊髄損傷後の神経障害に対する治療剤 |
| JPH08301783A (ja) | 1995-05-11 | 1996-11-19 | Mochida Pharmaceut Co Ltd | 吸収性骨疾患予防・治療剤 |
| EP0743066A3 (en) | 1995-05-16 | 1998-09-30 | Mitsui Pharmaceuticals, Inc. | Wound-healing agent |
| JP3931353B2 (ja) | 1995-06-30 | 2007-06-13 | 持田製薬株式会社 | 創傷治癒剤 |
| JP3745805B2 (ja) | 1995-10-24 | 2006-02-15 | 日本ケミカルリサーチ株式会社 | トロンボモジュリンの精製方法 |
| JPH101439A (ja) | 1996-06-11 | 1998-01-06 | Mochida Pharmaceut Co Ltd | 神経変性疾患治療剤 |
| JP4157644B2 (ja) | 1998-03-30 | 2008-10-01 | 旭化成ファーマ株式会社 | 高純度可溶性トロンボモジュリンの製造方法 |
| PT1267915E (pt) * | 2000-03-28 | 2005-09-30 | Lilly Co Eli | Metodos para tratar doencas com proteina c activada |
| US20020111296A1 (en) | 2000-08-31 | 2002-08-15 | Festoff Barry W. | Thrombomodulin analogs for use in recovery of spinal cord injury |
| JP4340540B2 (ja) * | 2002-01-18 | 2009-10-07 | 旭化成ファーマ株式会社 | 可溶性トロンボモジュリン高濃度含有製剤 |
| EP2017276B1 (en) * | 2003-09-22 | 2011-01-19 | Euro-Celtique S.A. | Phenyl-carboxamide compounds useful for treating pain |
| US20080280774A1 (en) * | 2005-02-16 | 2008-11-13 | Wyeth | Methods and Systems for Diagnosis, Prognosis and Selection of Treatment of Leukemia |
| US9394267B2 (en) | 2007-07-13 | 2016-07-19 | The Cleveland Clinic Foundation | Heterocyclic modulators of cannabinoid receptors |
| CN101801187B (zh) | 2007-07-13 | 2014-07-23 | 得克萨斯系统大学评议会 | 大麻素受体的杂环调节剂 |
| KR20110008166A (ko) * | 2008-02-18 | 2011-01-26 | 라보라토리오스 델 드라. 에스테브.에스.에이. | 화학요법의 결과로 발생하는 신경병적 통증의 치료를 위한 시그마 수용체 리간드에 결합하는 화합물들의 용도 |
| US20110144024A1 (en) * | 2008-07-16 | 2011-06-16 | Paion Deutschland Gmbh | Prevention and treatment of radiation injury |
| TWI438009B (zh) * | 2010-02-19 | 2014-05-21 | Teikoku Pharma Usa Inc | 紫杉烷前－乳劑調配物及其製造與使用之方法 |
| JP2011178687A (ja) * | 2010-02-26 | 2011-09-15 | Kochi Univ | 造血細胞移植に伴う疼痛の予防および／または治療剤 |
| US20110287110A1 (en) * | 2010-04-23 | 2011-11-24 | Mark Wesley Dewhirst | Combination cancer treatment |
| JP5924611B2 (ja) | 2010-06-16 | 2016-05-25 | 国立大学法人高知大学 | 造血細胞移植に伴う生着症候群の予防及び／又は治療のための医薬 |
| JP2013533286A (ja) * | 2010-07-30 | 2013-08-22 | セントルイス ユニバーシティ | 疼痛を治療する方法 |
| IN2014DN10075A (en:Method) | 2012-05-31 | 2015-08-21 | Univ Kinki |
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2013
- 2013-05-17 IN IN10075DEN2014 patent/IN2014DN10075A/en unknown
- 2013-05-17 CA CA2875069A patent/CA2875069C/en active Active
- 2013-05-17 US US14/404,222 patent/US10709767B2/en active Active
- 2013-05-17 KR KR1020147032155A patent/KR101672114B1/ko active Active
- 2013-05-17 AU AU2013268725A patent/AU2013268725B2/en active Active
- 2013-05-17 BR BR112014028852-6A patent/BR112014028852A2/pt not_active Application Discontinuation
- 2013-05-17 PT PT13796572T patent/PT2857037T/pt unknown
- 2013-05-17 WO PCT/JP2013/063743 patent/WO2013179910A1/ja not_active Ceased
- 2013-05-17 JP JP2014518384A patent/JP6124417B2/ja active Active
- 2013-05-17 PL PL13796572T patent/PL2857037T3/pl unknown
- 2013-05-17 ES ES13796572T patent/ES2743767T3/es active Active
- 2013-05-17 DK DK13796572.9T patent/DK2857037T3/da active
- 2013-05-17 HU HUE13796572A patent/HUE045997T2/hu unknown
- 2013-05-17 RU RU2014148171/15A patent/RU2595857C2/ru active
- 2013-05-17 CN CN201380028318.4A patent/CN104394885B/zh active Active
- 2013-05-17 MX MX2014014505A patent/MX364934B/es active IP Right Grant
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