CA2858285C - 1,3-diphenylpropane derivatives, preparations and uses thereof - Google Patents

1,3-diphenylpropane derivatives, preparations and uses thereof Download PDF

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Publication number
CA2858285C
CA2858285C CA2858285A CA2858285A CA2858285C CA 2858285 C CA2858285 C CA 2858285C CA 2858285 A CA2858285 A CA 2858285A CA 2858285 A CA2858285 A CA 2858285A CA 2858285 C CA2858285 C CA 2858285C
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Prior art keywords
methyl
disease
group
dimethylphenoxy
phenyl
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CA2858285A
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French (fr)
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CA2858285A1 (en
Inventor
Mathieu DUBERNET
Jean-Francois Delhomel
Karine Bertrand
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Genfit SA
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Genfit SA
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • A—HUMAN NECESSITIES
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/19—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to acyclic carbon atoms of the carbon skeleton
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    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Diabetes (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
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  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
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  • Obesity (AREA)
  • Reproductive Health (AREA)
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  • Pulmonology (AREA)
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  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
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CA2858285A 2011-12-28 2012-12-28 1,3-diphenylpropane derivatives, preparations and uses thereof Active CA2858285C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11306790 2011-12-28
EP11306790.4 2011-12-28
PCT/EP2012/077026 WO2013098374A1 (en) 2011-12-28 2012-12-28 1,3-diphenylpropane derivatives, preparations and uses thereof

Publications (2)

Publication Number Publication Date
CA2858285A1 CA2858285A1 (en) 2013-07-04
CA2858285C true CA2858285C (en) 2021-06-08

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CA2858285A Active CA2858285C (en) 2011-12-28 2012-12-28 1,3-diphenylpropane derivatives, preparations and uses thereof

Country Status (17)

Country Link
US (1) US9115073B2 (https=)
EP (1) EP2811992A1 (https=)
JP (1) JP6140729B2 (https=)
KR (1) KR102023667B1 (https=)
CN (1) CN104185471B (https=)
AU (1) AU2012360796B2 (https=)
BR (1) BR112014016129B1 (https=)
CA (1) CA2858285C (https=)
EA (1) EA031899B9 (https=)
HK (1) HK1203061A1 (https=)
IL (1) IL233172A (https=)
IN (1) IN2014DN05789A (https=)
MX (1) MX362862B (https=)
PH (1) PH12014501443A1 (https=)
SG (1) SG11201403107TA (https=)
WO (1) WO2013098374A1 (https=)
ZA (1) ZA201405459B (https=)

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KR101761767B1 (ko) 2015-03-04 2017-07-26 한국과학기술연구원 찰콘 유도체를 포함하는 신독성 감소용 조성물
FR3050112B1 (fr) 2016-04-15 2020-09-04 Soc Civ Immobiliere Gecinq Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques
CN113677336B (zh) 2019-04-10 2024-04-30 基恩菲特公司 包含式(i)化合物和glp-1受体激动剂的组合疗法
KR20240018778A (ko) * 2022-08-03 2024-02-14 포항공과대학교 산학협력단 신규 ppar 활성 조절물질을 유효성분으로 포함하는 퇴행성 뇌질환의 예방, 개선 또는 치료용 조성물
CN120392721A (zh) * 2024-01-30 2025-08-01 哈尔滨三联药业股份有限公司 PPARα/δ双重激动剂在治疗多囊肾疾病中的应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2841900B1 (fr) 2002-07-08 2007-03-02 Genfit S A Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations
US7547729B2 (en) * 2004-01-08 2009-06-16 Genfit 1,3-diphenylprop-2-en-1-one derivative compounds, preparation method thereof and uses of same
FR2902789A1 (fr) * 2006-06-21 2007-12-28 Genfit Sa Derives de 1,3-diphenylpropane substitues, preparations et utilisations
FR2910892A1 (fr) * 2006-12-29 2008-07-04 Genfit Sa Derives de 1,3-diphenylpropane substitues, preparations et utilisations.

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SG11201403107TA (en) 2014-09-26
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