MX362862B - Derivados de 1,3-difenilpropano, preparaciones y usos de los mismos. - Google Patents

Derivados de 1,3-difenilpropano, preparaciones y usos de los mismos.

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Publication number
MX362862B
MX362862B MX2014007956A MX2014007956A MX362862B MX 362862 B MX362862 B MX 362862B MX 2014007956 A MX2014007956 A MX 2014007956A MX 2014007956 A MX2014007956 A MX 2014007956A MX 362862 B MX362862 B MX 362862B
Authority
MX
Mexico
Prior art keywords
present
preparations
diphenylpropane derivatives
metabolic
diverse
Prior art date
Application number
MX2014007956A
Other languages
English (en)
Other versions
MX2014007956A (es
Inventor
Dubernet Mathieu
Delhomel Jean-François
Bertrand Karine
Original Assignee
Genfit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genfit filed Critical Genfit
Publication of MX2014007956A publication Critical patent/MX2014007956A/es
Publication of MX362862B publication Critical patent/MX362862B/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • A—HUMAN NECESSITIES
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/19—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to acyclic carbon atoms of the carbon skeleton
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    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

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Abstract

La invención actual se refiere a derivados de 1,3-difenilpropan novedosos, composiciones farmacéuticas que comprenden los mismos y usos terapéuticos de los mismos, en particular en los campos de salud humana y animal. Los compuestos de acuerdo con la invención actual tienen propiedades agonistas de PPAR intrínsecas. Estos por lo tanto son de interés particular en el tratamiento de enfermedades metabólicas e/o inflamatorias y particularmente enfermedades periféricas y centrales asociadas con el síndrome metabólico, tales como diversas formas de esteatohepatitis, diabetes tipo 2, trastornos neurodegenerativos diversos, tales como enfermedad de Alzheimer, mal de Parkinson y esclerosis múltiple.
MX2014007956A 2011-12-28 2012-12-28 Derivados de 1,3-difenilpropano, preparaciones y usos de los mismos. MX362862B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11306790 2011-12-28
PCT/EP2012/077026 WO2013098374A1 (en) 2011-12-28 2012-12-28 1,3-diphenylpropane derivatives, preparations and uses thereof

Publications (2)

Publication Number Publication Date
MX2014007956A MX2014007956A (es) 2014-08-21
MX362862B true MX362862B (es) 2019-02-20

Family

ID=47470024

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014007956A MX362862B (es) 2011-12-28 2012-12-28 Derivados de 1,3-difenilpropano, preparaciones y usos de los mismos.

Country Status (17)

Country Link
US (1) US9115073B2 (es)
EP (1) EP2811992A1 (es)
JP (1) JP6140729B2 (es)
KR (1) KR102023667B1 (es)
CN (1) CN104185471B (es)
AU (1) AU2012360796B2 (es)
BR (1) BR112014016129B1 (es)
CA (1) CA2858285C (es)
EA (1) EA031899B9 (es)
HK (1) HK1203061A1 (es)
IL (1) IL233172A (es)
IN (1) IN2014DN05789A (es)
MX (1) MX362862B (es)
PH (1) PH12014501443A1 (es)
SG (1) SG11201403107TA (es)
WO (1) WO2013098374A1 (es)
ZA (1) ZA201405459B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101761767B1 (ko) 2015-03-04 2017-07-26 한국과학기술연구원 찰콘 유도체를 포함하는 신독성 감소용 조성물
FR3050112B1 (fr) 2016-04-15 2020-09-04 Soc Civ Immobiliere Gecinq Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2841900B1 (fr) 2002-07-08 2007-03-02 Genfit S A Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations
EP1701938B1 (fr) * 2004-01-08 2012-07-25 Genfit Composes derives de 1,3-diphenylprop-2-en-1-one, preparation et utilisations
FR2902789A1 (fr) * 2006-06-21 2007-12-28 Genfit Sa Derives de 1,3-diphenylpropane substitues, preparations et utilisations
FR2910892A1 (fr) * 2006-12-29 2008-07-04 Genfit Sa Derives de 1,3-diphenylpropane substitues, preparations et utilisations.

Also Published As

Publication number Publication date
NZ626718A (en) 2016-01-29
US20140350112A1 (en) 2014-11-27
JP6140729B2 (ja) 2017-05-31
KR20140131507A (ko) 2014-11-13
WO2013098374A1 (en) 2013-07-04
IN2014DN05789A (es) 2015-05-15
ZA201405459B (en) 2016-07-27
BR112014016129A8 (pt) 2021-04-27
US9115073B2 (en) 2015-08-25
EA201400761A1 (ru) 2015-05-29
JP2015507627A (ja) 2015-03-12
CN104185471B (zh) 2018-03-30
EA031899B1 (ru) 2019-03-29
KR102023667B1 (ko) 2019-09-23
AU2012360796A1 (en) 2014-07-24
BR112014016129B1 (pt) 2022-04-05
BR112014016129A2 (pt) 2017-06-13
IL233172A0 (en) 2014-07-31
HK1203061A1 (en) 2015-10-16
EA031899B9 (ru) 2019-08-30
AU2012360796B2 (en) 2017-02-02
MX2014007956A (es) 2014-08-21
CN104185471A (zh) 2014-12-03
SG11201403107TA (en) 2014-09-26
PH12014501443B1 (en) 2014-10-08
CA2858285C (en) 2021-06-08
IL233172A (en) 2016-06-30
PH12014501443A1 (en) 2014-10-08
EP2811992A1 (en) 2014-12-17
CA2858285A1 (en) 2013-07-04

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