BR112014016129B1 - Composto, derivado de 1,3-difenilpropano e composição farmacêutica - Google Patents

Composto, derivado de 1,3-difenilpropano e composição farmacêutica Download PDF

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BR112014016129B1
BR112014016129B1 BR112014016129-1A BR112014016129A BR112014016129B1 BR 112014016129 B1 BR112014016129 B1 BR 112014016129B1 BR 112014016129 A BR112014016129 A BR 112014016129A BR 112014016129 B1 BR112014016129 B1 BR 112014016129B1
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Prior art keywords
disease
methyl
cyclopropyl
phenyl
group
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BR112014016129-1A
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Portuguese (pt)
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BR112014016129A8 (pt
BR112014016129A2 (pt
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Mathieu Dubernet
Jean-François Delhomel
Karine Bertrand
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Genfit
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/19—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

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  • Diabetes (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
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  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
BR112014016129-1A 2011-12-28 2012-12-28 Composto, derivado de 1,3-difenilpropano e composição farmacêutica BR112014016129B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11306790 2011-12-28
EP11306790.4 2011-12-28
PCT/EP2012/077026 WO2013098374A1 (en) 2011-12-28 2012-12-28 1,3-diphenylpropane derivatives, preparations and uses thereof

Publications (3)

Publication Number Publication Date
BR112014016129A2 BR112014016129A2 (pt) 2017-06-13
BR112014016129A8 BR112014016129A8 (pt) 2021-04-27
BR112014016129B1 true BR112014016129B1 (pt) 2022-04-05

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BR112014016129-1A BR112014016129B1 (pt) 2011-12-28 2012-12-28 Composto, derivado de 1,3-difenilpropano e composição farmacêutica

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US (1) US9115073B2 (https=)
EP (1) EP2811992A1 (https=)
JP (1) JP6140729B2 (https=)
KR (1) KR102023667B1 (https=)
CN (1) CN104185471B (https=)
AU (1) AU2012360796B2 (https=)
BR (1) BR112014016129B1 (https=)
CA (1) CA2858285C (https=)
EA (1) EA031899B9 (https=)
HK (1) HK1203061A1 (https=)
IL (1) IL233172A (https=)
IN (1) IN2014DN05789A (https=)
MX (1) MX362862B (https=)
PH (1) PH12014501443A1 (https=)
SG (1) SG11201403107TA (https=)
WO (1) WO2013098374A1 (https=)
ZA (1) ZA201405459B (https=)

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KR101761767B1 (ko) 2015-03-04 2017-07-26 한국과학기술연구원 찰콘 유도체를 포함하는 신독성 감소용 조성물
FR3050112B1 (fr) 2016-04-15 2020-09-04 Soc Civ Immobiliere Gecinq Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques
CN113677336B (zh) 2019-04-10 2024-04-30 基恩菲特公司 包含式(i)化合物和glp-1受体激动剂的组合疗法
KR20240018778A (ko) * 2022-08-03 2024-02-14 포항공과대학교 산학협력단 신규 ppar 활성 조절물질을 유효성분으로 포함하는 퇴행성 뇌질환의 예방, 개선 또는 치료용 조성물
CN120392721A (zh) * 2024-01-30 2025-08-01 哈尔滨三联药业股份有限公司 PPARα/δ双重激动剂在治疗多囊肾疾病中的应用

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Publication number Priority date Publication date Assignee Title
FR2841900B1 (fr) 2002-07-08 2007-03-02 Genfit S A Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations
US7547729B2 (en) * 2004-01-08 2009-06-16 Genfit 1,3-diphenylprop-2-en-1-one derivative compounds, preparation method thereof and uses of same
FR2902789A1 (fr) * 2006-06-21 2007-12-28 Genfit Sa Derives de 1,3-diphenylpropane substitues, preparations et utilisations
FR2910892A1 (fr) * 2006-12-29 2008-07-04 Genfit Sa Derives de 1,3-diphenylpropane substitues, preparations et utilisations.

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US20140350112A1 (en) 2014-11-27
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CA2858285A1 (en) 2013-07-04
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CN104185471A (zh) 2014-12-03
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IL233172A (en) 2016-06-30
AU2012360796A1 (en) 2014-07-24
CN104185471B (zh) 2018-03-30
EA031899B1 (ru) 2019-03-29
EA201400761A1 (ru) 2015-05-29
BR112014016129A8 (pt) 2021-04-27
PH12014501443A1 (en) 2014-10-08
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