CA2831165A1 - Nutritional compositions having .alpha.-hica and citrulline and methods of using same - Google Patents

Nutritional compositions having .alpha.-hica and citrulline and methods of using same Download PDF

Info

Publication number
CA2831165A1
CA2831165A1 CA2831165A CA2831165A CA2831165A1 CA 2831165 A1 CA2831165 A1 CA 2831165A1 CA 2831165 A CA2831165 A CA 2831165A CA 2831165 A CA2831165 A CA 2831165A CA 2831165 A1 CA2831165 A1 CA 2831165A1
Authority
CA
Canada
Prior art keywords
nutritional composition
composition according
individual
per day
combinations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2831165A
Other languages
English (en)
French (fr)
Inventor
Norman Alan Greenberg
Denis Breuille
Zamzam Kabiry ROUGHEAD (Fariba)
Doug Bolster
Jennifer Mager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nestec SA
Original Assignee
Nestec SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec SA filed Critical Nestec SA
Publication of CA2831165A1 publication Critical patent/CA2831165A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/064Saccharomycetales, e.g. baker's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E10/00Energy generation through renewable energy sources
    • Y02E10/70Wind energy
    • Y02E10/72Wind turbines with rotation axis in wind direction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Pediatric Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
CA2831165A 2011-04-18 2012-04-18 Nutritional compositions having .alpha.-hica and citrulline and methods of using same Abandoned CA2831165A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161476345P 2011-04-18 2011-04-18
US61/476,345 2011-04-18
PCT/EP2012/057093 WO2012143403A1 (en) 2011-04-18 2012-04-18 Nutritional compositions having alpha-hica and citrulline

Publications (1)

Publication Number Publication Date
CA2831165A1 true CA2831165A1 (en) 2012-10-26

Family

ID=45976400

Family Applications (4)

Application Number Title Priority Date Filing Date
CA2831165A Abandoned CA2831165A1 (en) 2011-04-18 2012-04-18 Nutritional compositions having .alpha.-hica and citrulline and methods of using same
CA2832150A Abandoned CA2832150A1 (en) 2011-04-18 2012-04-18 Nutritional compositions having alpha-hica and alpha-ketoglutarate
CA2832507A Abandoned CA2832507A1 (en) 2011-04-18 2012-04-18 Nutritional compositions having alpha-hica and eicosapentaenoic acid
CA2831001A Abandoned CA2831001A1 (en) 2011-04-18 2012-04-18 Nutritional compositions comprising alpha-hydroxyisocaproic acid

Family Applications After (3)

Application Number Title Priority Date Filing Date
CA2832150A Abandoned CA2832150A1 (en) 2011-04-18 2012-04-18 Nutritional compositions having alpha-hica and alpha-ketoglutarate
CA2832507A Abandoned CA2832507A1 (en) 2011-04-18 2012-04-18 Nutritional compositions having alpha-hica and eicosapentaenoic acid
CA2831001A Abandoned CA2831001A1 (en) 2011-04-18 2012-04-18 Nutritional compositions comprising alpha-hydroxyisocaproic acid

Country Status (13)

Country Link
US (4) US20140056862A1 (enExample)
EP (4) EP2699112A1 (enExample)
JP (4) JP2014511890A (enExample)
CN (4) CN103458710A (enExample)
AU (4) AU2012244751A1 (enExample)
BR (2) BR112013026706A2 (enExample)
CA (4) CA2831165A1 (enExample)
MX (4) MX2013012230A (enExample)
PH (4) PH12013502012A1 (enExample)
RU (4) RU2013151083A (enExample)
SG (4) SG194028A1 (enExample)
WO (4) WO2012143402A1 (enExample)
ZA (4) ZA201308606B (enExample)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2583566T3 (pl) * 2011-10-21 2016-01-29 Nestec Sa Micele serwatkowego białka do zwiększania masy mięśni i sprawności
EP2583563A1 (en) * 2011-10-21 2013-04-24 Nestec S.A. Whey protein micelles against muscle atrophy and sarcopenia
ITBO20120226A1 (it) * 2012-04-24 2013-10-25 Alfa Wassermann Spa Composizioni comprendenti ornitina alfa-chetoglutarato, processi per il loro ottenimento e il loro uso.
CN103783532B (zh) * 2012-10-29 2016-06-08 杭州纽曲星生物科技有限公司 一种抗老年性肌肉衰减的复合蛋白质粉及其制备方法
CA2909211C (en) * 2013-04-15 2021-06-22 Nestec S.A. Use of whey protein in combination with electrical muscle stimulation
ES2636479T3 (es) * 2013-06-10 2017-10-05 N.V. Nutricia Conservación muscular en el adulto con sobrepeso u obesidad durante un programa de pérdida de peso
US9878004B2 (en) 2013-09-25 2018-01-30 Axcella Health Inc. Compositions and formulations for treatment of gastrointestinal tract malabsorption diseases and inflammatory conditions and methods of production and use thereof
AU2014333977B2 (en) 2013-10-09 2019-12-19 Société des Produits Nestlé S.A. Compositions comprising citrulline and leucine and their use in the treatment of diabetes and metabolic syndrome
CN103637212B (zh) * 2013-12-13 2014-12-24 广东省农业科学院蚕业与农产品加工研究所 一种具有降血脂作用的管饲临床营养品及其制备方法
EP3115047B1 (en) * 2014-03-07 2020-05-06 Ajinomoto Co., Inc. Debility preventative
WO2015137387A1 (ja) * 2014-03-11 2015-09-17 協和発酵バイオ株式会社 筋肉増強剤
MX2016012427A (es) 2014-03-26 2017-04-27 Abbott Lab Suplemento alimenticio en polvo.
US20190054093A1 (en) * 2014-04-04 2019-02-21 Nektium Pharma Sl Treatment of sarcopenia with ecdysteroids
WO2015160262A1 (en) * 2014-04-16 2015-10-22 Amerikal Nutraceutical Corp Anti-aging composition
MX2016015973A (es) * 2014-06-03 2017-03-08 Abbott Lab Mezclas de proteinas basadas en papa y composiciones nutricionales con proteina de patata.
US11102994B2 (en) * 2014-08-21 2021-08-31 Clearfast Inc. Pre-operative carbohydrate-rich beverage composition and methods of treatment
WO2016044167A1 (en) * 2014-09-15 2016-03-24 Abbott Laboratories Methods for increasing muscle strength and mobility in subjects experiencing significant physical inactivity using gamma linolenic acid
ES2960218T3 (es) * 2014-10-14 2024-03-01 Nestle Sa Mejora en la funcionalidad del músculo de hombres ancianos
US11040022B2 (en) 2015-02-05 2021-06-22 William H. Cross, III Compositions and methods for pain relief
NL2015032B1 (en) * 2015-06-26 2017-01-24 Vitalnext B V Compositions and methods for the treatment of malnutrition.
US10674746B2 (en) 2015-10-27 2020-06-09 Cytozyme Animal Nutrition, Inc. Animal nutrition compositions and related methods
CN108473384A (zh) 2015-10-27 2018-08-31 细胞酶动物营养品公司 动物营养成分及相关方法
RU2614881C1 (ru) * 2015-12-29 2017-03-30 Общество с ограниченной ответственностью "Мобильный доктор" Комплекс биологически активных веществ, защищающих спортсменов от перетренированности
EP3397960B1 (en) * 2015-12-30 2020-01-29 Société des Produits Nestlé S.A. Method for determining fat free body mass
US10912323B2 (en) 2016-02-29 2021-02-09 Abbott Laboratories Nutritional supplement powder
US11612632B2 (en) 2017-04-25 2023-03-28 William H. Cross, III Compositions and methods for treatment of prediabetes
ES2851923T3 (es) * 2016-05-20 2021-09-09 Nestle Sa Triglicéridos de cadena intermedia para el tratamiento de enfermedad degenerativa de la válvula mitral en animales de compañía
CN106213522A (zh) * 2016-08-05 2016-12-14 郑家福 营养保健品
RU2635373C1 (ru) * 2016-08-25 2017-11-13 Федеральное государственное бюджетное образовательное учреждение высшего образования "Национальный исследовательский Мордовский государственный университет им. Н.П. Огарёва" Биологически активная добавка для повышения общей работоспособности
RU2762607C2 (ru) 2016-09-13 2021-12-21 Аллерган, Инк. Стабилизированные небелковые композиции клостридиального токсина
CN109982585B (zh) * 2016-11-16 2024-03-15 费森尤斯卡比德国有限公司 用于患有肌少症和/或衰弱症的患者或肌少症前期和/或衰弱症前期患者的疗法中的用途的营养组合物
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
KR20180081361A (ko) * 2017-01-06 2018-07-16 연세대학교 산학협력단 인돌-3-카비놀 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 근육 질환 예방 또는 치료용 조성물
US12213952B1 (en) 2017-03-09 2025-02-04 Heh Research & Development Services, Inc. Biologic enhancement formulation
WO2020106746A1 (en) * 2018-11-19 2020-05-28 Heh Research & Development Services, Inc. Biologic enhancement formulation
US20200188327A1 (en) * 2017-04-25 2020-06-18 Buck Institute For Research On Aging Formulations for extending lifespan and healthspan
SG11201912551UA (en) 2017-06-21 2020-01-30 Abbott Lab Methods for increasing growth of beneficial bacteria in the gastrointestinal tract
CN107242572A (zh) * 2017-07-06 2017-10-13 广州彤博士健康科技有限公司 营养补充剂及制备方法
BR112020002419A2 (pt) 2017-08-14 2020-07-28 Axcella Health Inc. aminoácido para o tratamento de doença do fígado
CN107616505B (zh) * 2017-10-24 2020-12-25 精晶药业股份有限公司 一种含有鸟氨酸酮戊二酸的保健品及其制备方法
PL238310B1 (pl) * 2017-10-31 2021-08-09 Top Energy Set Spolka Z Ograniczona Odpowiedzialnoscia Preparat leczniczy oraz sposób jego uzyskiwania
US11304971B2 (en) 2018-01-31 2022-04-19 William H. Cross, III Metformin compositions and methods for treatment of diabetes
US11351188B2 (en) 2018-01-31 2022-06-07 William H. Cross, III Folic compositions and methods for treatment of diabetic neuropathies
US11154523B2 (en) 2018-01-31 2021-10-26 William H. Cross, III Compositions and methods for treatment of diabetic neuropathies
US12329818B2 (en) 2018-02-22 2025-06-17 William H. Cross, III Topical compositions and methods for treatment of diabetic neuropathies
EP3810123A1 (en) 2018-06-20 2021-04-28 Axcella Health Inc. Compositions and methods for the treatment of fat infiltration in muscle
SG11202102204PA (en) 2018-09-25 2021-04-29 Ponce De Leon Health Designated Activity Company Process of making calcium alpha-ketoglutarate
KR102171518B1 (ko) * 2019-02-21 2020-10-29 한양대학교 에리카산학협력단 지골피 추출물을 유효성분으로 함유하는 근 위축 예방 또는 치료용 조성물
WO2020240500A1 (en) * 2019-05-31 2020-12-03 Societe Des Produits Nestle Sa Mct-based nutrition blend for providing health benefits in animals
CA3142781A1 (en) * 2019-06-10 2020-12-17 Buck Institute For Research On Aging Methods and compositions for altering senescence associated secretory phenotype
CN110226756A (zh) * 2019-06-18 2019-09-13 山东理工大学 预防和缓解2型糖尿病患者肌少症的蛋白组件及制备方法
TWI774966B (zh) * 2019-06-25 2022-08-21 生合生物科技股份有限公司 胚芽乳桿菌bcrc 910734用於提升老年個體的肌力以及治療肌肉減少症的用途
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
US11969502B2 (en) 2019-12-09 2024-04-30 Nicoventures Trading Limited Oral products
WO2021133962A1 (en) * 2019-12-27 2021-07-01 Grove Collaborative, Inc. Confections for skin protection: compositions, methods for making, and applications thereof
BR112022019122A2 (pt) * 2020-03-30 2022-11-08 Gervais Danone Sa Uso de uma composição de leite fermentado e método para suplementação dietética de metabólitos de bcaa
JP7742026B2 (ja) * 2020-04-03 2025-09-19 三菱瓦斯化学株式会社 筋肉増強剤
CA3188646A1 (en) * 2020-07-02 2022-01-06 Ponce De Leon Health Designated Activity Company Compositions and methods for treating crp-mediated diseases
CN116209450B (zh) * 2020-08-18 2024-08-09 食品科学有限责任企业 聚合乳清蛋白包封的抗氧化化合物及其制备方法
FI129515B (en) * 2020-11-06 2022-03-31 Salarusta Oy FOR USE IN THE PREVENTION AND / OR TREATMENT OF A DISEASE OR CONDITION RELATED TO THE DEGRADATION AND / OR DISTURBANCE OF THE DEGREE OF MONTOOSASE AND / OR INTEGRITY
CN112899204B (zh) * 2021-03-19 2022-06-28 杭州百芮生物科技有限公司 一种益生菌冻干外壳复合保护剂及其应用
CN113398144B (zh) * 2021-07-27 2022-04-01 陈玉松 核苷酸混合物在制备预防或缓解老年肌少症制剂中的应用
CN114029085B (zh) * 2021-12-06 2024-02-27 中触媒新材料股份有限公司 一种烯烃环氧化催化剂及其制备方法和应用
WO2023121696A1 (en) * 2021-12-20 2023-06-29 Schneider Todd C Formulation and treatment for extended micronutrient therapy
WO2025151881A1 (en) * 2024-01-12 2025-07-17 Heh Research & Development Services, Inc. Biologic enhancement formulation

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2335215B2 (de) * 1972-07-13 1979-04-05 The Johns Hopkins University, Baltimore, Md. (V.St.A.) Verwendung einer Mischung bei der Bekämpfung von zur Urämie führenden Nierenerkrankungen
GB1442154A (en) * 1973-04-30 1976-07-07 Walser M Composition for promotion of protein synthesis and suppression of urea formation in the body
GB1444621A (en) * 1973-04-30 1976-08-04 Walser M Composition for promotion of protein synthesis and suppression of urea formation in the body utilizing alpha-hydroxy-acid analogues of amino acids
GB1511302A (en) * 1974-04-15 1978-05-17 Univ Johns Hopkins Pharmaceutical compositions comprising amino acid analogues
US4752619A (en) 1985-12-23 1988-06-21 The Johns Hopkins University Nutritional supplement for treatment of uremia
SE8803144L (sv) * 1988-09-07 1990-03-08 Kabivitrum Ab Energisubstrat
US5646187A (en) * 1992-05-20 1997-07-08 Ab Erik Vinnars Use of alpha-ketoglutarate
SE9201584D0 (sv) * 1992-05-20 1992-05-20 Vinnars Erik Ab Use of alpha-ketoglutarate
SE0201713D0 (sv) * 2001-11-23 2002-06-06 Gramineer Internat Ab New methods and use III
US20040087490A1 (en) * 2002-09-20 2004-05-06 Troup John P. Nutritional compositions
US8795693B2 (en) * 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US20050256192A1 (en) * 2004-04-30 2005-11-17 Gardiner Paul T Nutritional composition for enhancing lean muscle stimulus, growth, strength and recovery, creating and prolonging intense muscle pumps, supporting endurance, strength, performance, size and stamina, providing a transducer effect for nitric oxide, increasing nutrient delivery and/or promoting increased vascular response in an individual
FI20045395A7 (fi) * 2004-10-21 2006-04-22 Oy Elmomed Ltd Ravintoainelisä ja sen käyttö
AR053295A1 (es) * 2005-05-23 2007-04-25 Cadbury Adams Usa Llc Composiciones que potencian el sabor y golosinas comestibles y productos de goma de mascar que los contienen
CN101179943B (zh) * 2005-05-23 2013-06-26 卡夫食品环球品牌有限责任公司 填充液体的咀嚼型胶基糖组合物
EP1774973A1 (en) * 2005-10-12 2007-04-18 Nutricia N.V. Leucine rich composition
WO2007053943A1 (en) * 2005-11-08 2007-05-18 Multi Formulations Ltd. The use of compositions comprising ketoacids and amino acids for increasing muscle mass and muscle performance
CA2633292C (en) * 2005-12-16 2015-04-28 N.V. Nutricia Use of soluble dietary fibres against muscle wasting
US20100222282A1 (en) * 2006-01-19 2010-09-02 Entress Ab Method of diagnosis and method of treatment
CA2642761A1 (en) * 2006-02-23 2007-08-30 Iomedix Sleep International Srl Compositions and methods for the induction and maintenance of quality sleep
RU2420210C2 (ru) * 2006-03-23 2011-06-10 Нестек С.А. Высококалорийная питательная добавка
RU2444355C2 (ru) * 2006-04-04 2012-03-10 Нестек С.А. Способы лечения с применением цитруллина
CN101415414B (zh) * 2006-04-04 2013-06-12 雀巢产品技术援助有限公司 瓜氨酸在制备治疗矫正脓毒症患者中精氨酸缺乏的药物中的用途
PL379512A1 (pl) * 2006-04-21 2007-10-29 Sgp & Sons Ab Nowe metody i ich zastosowanie
CA2660291C (en) * 2006-08-09 2011-11-22 The Iams Company Methods of improving bone health and muscle health
FR2913885B1 (fr) * 2007-03-22 2012-07-20 Univ Paris Descartes Utilisation de la citrulline pour le traitement des pathologies liees a une augmentation de la carbonylation des proteines
EP2192898A1 (en) * 2007-09-11 2010-06-09 Northern Innovations And Formulations Corp. Composition and method for increasing the anabolic state of muscle cells
CA2610820A1 (en) * 2007-12-12 2008-12-29 Michele Molino Method for maintaining physiological ph levels during intensive physical exercise
US20090156647A1 (en) * 2007-12-12 2009-06-18 Iovate T. & P. Inc. Method for maintaining physiological pH levels during intensive physical exercise
WO2010002242A1 (en) * 2008-07-02 2010-01-07 N.V. Nutricia Nutritional composition for improving muscle function and daily activity
JP2010105946A (ja) * 2008-10-29 2010-05-13 Nof Corp 筋タンパク質増強剤及びこれを含む医薬品または食品
WO2010108016A2 (en) * 2009-03-18 2010-09-23 Healthspan Solutions, Llc Compositions and methods for sparing muscle in renal insufficiency and during hemodialysis
WO2010137944A1 (en) * 2009-05-27 2010-12-02 N.V. Nutricia Treatment of hypercalcaemia
RU2012105901A (ru) * 2009-07-20 2013-08-27 Нестек С.А. Способы снижения потери функционального состояния
CA2771283A1 (en) * 2009-08-13 2011-02-17 Nestec S.A. Nutritional compositions including exogenous nucleotides
RU2012114832A (ru) * 2009-09-14 2013-10-27 Нестек С.А. Питательные композиции для модулирования воспаления, содержащие экзогенный витамин к2

Also Published As

Publication number Publication date
US20140037604A1 (en) 2014-02-06
RU2013151090A (ru) 2015-05-27
CA2832150A1 (en) 2012-10-26
CN103476274A (zh) 2013-12-25
JP2014511890A (ja) 2014-05-19
WO2012143403A1 (en) 2012-10-26
AU2012244749A1 (en) 2013-10-10
AU2012244751A1 (en) 2013-10-17
SG194065A1 (en) 2013-11-29
AU2012244750A1 (en) 2013-10-17
CN103458710A (zh) 2013-12-18
US20140044685A1 (en) 2014-02-13
AU2012244748A1 (en) 2013-10-10
CA2831001A1 (en) 2012-10-26
JP2014519483A (ja) 2014-08-14
CN103491804A (zh) 2014-01-01
MX2013012228A (es) 2013-12-06
AU2012244748B2 (en) 2016-07-14
PH12013501926A1 (en) 2013-10-14
SG193933A1 (en) 2013-11-29
BR112013026539A2 (pt) 2016-12-27
RU2013151083A (ru) 2015-05-27
SG194028A1 (en) 2013-11-29
ZA201308606B (en) 2015-05-27
EP2699111A1 (en) 2014-02-26
RU2013151085A (ru) 2015-05-27
ZA201308605B (en) 2015-05-27
WO2012143405A1 (en) 2012-10-26
CA2832507A1 (en) 2012-10-26
BR112013026706A2 (pt) 2016-12-27
MX2013012229A (es) 2013-12-06
EP2699110A1 (en) 2014-02-26
WO2012143402A1 (en) 2012-10-26
SG193938A1 (en) 2013-11-29
PH12013502027B1 (en) 2019-03-22
PH12013501927A1 (en) 2013-10-14
PH12013502012A1 (en) 2019-03-22
EP2699113A1 (en) 2014-02-26
CN103476275A (zh) 2013-12-25
ZA201308604B (en) 2015-05-27
MX2013012230A (es) 2014-06-05
US20140056862A1 (en) 2014-02-27
JP2014512372A (ja) 2014-05-22
PH12013502027A1 (en) 2013-12-16
US20140056863A1 (en) 2014-02-27
EP2699112A1 (en) 2014-02-26
JP2014512371A (ja) 2014-05-22
MX2013012231A (es) 2014-06-05
RU2013151087A (ru) 2015-05-27
ZA201308607B (en) 2015-05-27
WO2012143404A1 (en) 2012-10-26

Similar Documents

Publication Publication Date Title
CA2831165A1 (en) Nutritional compositions having .alpha.-hica and citrulline and methods of using same
EP2503906B1 (en) Nutritional compositions including a high protein component and exogenous nucleotides
AU2012241815A1 (en) Nutritional compositions including branched chain fatty acids and methods of using same
WO2011139621A1 (en) Nutritional compositions and methods for weaning from parenteral nutrition to enteral nutrition
WO2012130627A1 (en) Nutritional compositions for increasing arginine levels and methods of using same

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20180418