CA2813016C - Liquid pharmaceutical composition for the delivery of active ingredients - Google Patents
Liquid pharmaceutical composition for the delivery of active ingredients Download PDFInfo
- Publication number
- CA2813016C CA2813016C CA2813016A CA2813016A CA2813016C CA 2813016 C CA2813016 C CA 2813016C CA 2813016 A CA2813016 A CA 2813016A CA 2813016 A CA2813016 A CA 2813016A CA 2813016 C CA2813016 C CA 2813016C
- Authority
- CA
- Canada
- Prior art keywords
- composition
- active ingredient
- liquid
- particles
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10188242A EP2444063A1 (en) | 2010-10-20 | 2010-10-20 | Liquid pharmaceutical compositions for the delivery of active ingredients |
| EP10188242.1 | 2010-10-20 | ||
| PCT/EP2011/068141 WO2012052418A1 (en) | 2010-10-20 | 2011-10-18 | Liquid pharmaceutical composition for the delivery of active ingredients |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2813016A1 CA2813016A1 (en) | 2012-04-26 |
| CA2813016C true CA2813016C (en) | 2017-10-03 |
Family
ID=43608363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2813016A Active CA2813016C (en) | 2010-10-20 | 2011-10-18 | Liquid pharmaceutical composition for the delivery of active ingredients |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US9757459B2 (https=) |
| EP (2) | EP2444063A1 (https=) |
| JP (1) | JP5770297B2 (https=) |
| KR (1) | KR101773225B1 (https=) |
| CN (1) | CN103153281B (https=) |
| AU (1) | AU2011317673B2 (https=) |
| BR (1) | BR112013007473B1 (https=) |
| CA (1) | CA2813016C (https=) |
| DK (1) | DK2629754T3 (https=) |
| ES (1) | ES2528105T3 (https=) |
| IN (1) | IN2013DN02524A (https=) |
| MX (1) | MX2013003892A (https=) |
| PL (1) | PL2629754T3 (https=) |
| PT (1) | PT2629754E (https=) |
| WO (1) | WO2012052418A1 (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011113855A2 (en) | 2010-03-17 | 2011-09-22 | Novaliq Gmbh | Pharmaceutical composition for treatment of increased intraocular pressure |
| EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
| CN107397718A (zh) | 2011-05-25 | 2017-11-28 | 诺瓦利克有限责任公司 | 基于半氟化烷烃类的外用药物组合物 |
| KR101773648B1 (ko) | 2011-05-25 | 2017-08-31 | 노바리크 게엠베하 | 조갑에 투여를 위한 제약학적 조성물 |
| KR101989648B1 (ko) | 2012-01-23 | 2019-06-14 | 노바리크 게엠베하 | 부분불소화 알칸에 기초한 안정화된 단백질 조성물 |
| DK3181119T3 (da) | 2012-09-12 | 2019-09-16 | Novaliq Gmbh | Semifluorerede alkansammensætninger til anvendelse ved behandling af keratoconjunctivitis sicca |
| CN113679697A (zh) | 2012-09-12 | 2021-11-23 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| WO2014117035A1 (en) | 2013-01-24 | 2014-07-31 | Transderm, Inc. | COMPOSITIONS FOR TRANSDERMAL DELIVERY OF mTOR INHIBITORS |
| BR112016001522B1 (pt) | 2013-07-23 | 2019-10-01 | Novaliq Gmbh | Composições de anticorpo estabilizado |
| ES2863601T3 (es) * | 2014-09-17 | 2021-10-11 | Panoptica Inc | Formulaciones oculares para administración de fármacos y protección del segmento anterior del ojo |
| MX2018003781A (es) * | 2015-09-30 | 2018-09-12 | Novaliq Gmbh | Compuestos semifluorados para administracion oftalmica. |
| CN108348777B (zh) | 2015-09-30 | 2020-04-28 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| USRE50060E1 (en) | 2016-06-23 | 2024-07-30 | Novaliq Gmbh | Topical administration method |
| ES2969758T3 (es) | 2016-09-22 | 2024-05-22 | Novaliq Gmbh | Composiciones farmacéuticas para usar en la terapia de la blefaritis |
| US10813976B2 (en) | 2016-09-23 | 2020-10-27 | Novaliq Gmbh | Ophthalmic compositions comprising ciclosporin |
| AU2017333420A1 (en) * | 2016-09-28 | 2019-04-04 | Novaliq Gmbh | Compositions comprising a cannabinoid receptor binding ligand |
| US10751295B2 (en) * | 2016-11-09 | 2020-08-25 | Specialty Drug and Device, LLC | Compositions and methods for the removal of ear wax |
| EP3558308A1 (en) * | 2016-12-22 | 2019-10-30 | Novaliq GmbH | Compositions comprising tacrolimus for the treatment of intraocular inflammatory eye diseases |
| PT3399962T (pt) | 2016-12-23 | 2020-09-03 | Novaliq Gmbh | Composição oftálmica para o tratamento da doença do olho seco |
| JP7108631B2 (ja) | 2017-01-06 | 2022-07-28 | パルヴェラ セラピューティクス、インク． | ｍＴＯＲ阻害剤の無水組成物およびその使用方法 |
| CA3058097C (en) * | 2017-04-21 | 2024-01-02 | Novaliq Gmbh | Iodine compositions |
| US10717691B2 (en) | 2017-05-05 | 2020-07-21 | Novaliq Gmbh | Process for the production of semifluorinated alkanes |
| US11278503B2 (en) | 2017-05-12 | 2022-03-22 | Novaliq Gmbh | Pharmaceutical compositions comprising semifluorinated alkanes for the treatment of contact lense-related conditions |
| KR20200059272A (ko) | 2017-09-27 | 2020-05-28 | 노바리크 게엠베하 | 안구 질환의 치료에서의 사용을 위한 라타노프로스트를 포함하는 안과적 조성물 |
| CN111182893A (zh) | 2017-10-04 | 2020-05-19 | 诺瓦利克有限责任公司 | 包含f6h8的眼用组合物 |
| EP3758676A1 (en) | 2018-03-02 | 2021-01-06 | Novaliq GmbH | Pharmaceutical compositions comprising nebivolol |
| KR102882058B1 (ko) | 2018-03-28 | 2025-11-07 | 노바리크 게엠베하 | 티몰롤을 포함하는 약제학적 조성물 |
| JP2021522219A (ja) | 2018-04-27 | 2021-08-30 | ノバリック ゲーエムベーハー | 緑内障の治療のためのタフルプロストを含む眼科用組成物 |
| US11000513B2 (en) | 2018-07-02 | 2021-05-11 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
| WO2020064556A1 (en) | 2018-09-27 | 2020-04-02 | Novaliq Gmbh | Topical sunscreen formulation |
| WO2020064549A1 (en) | 2018-09-27 | 2020-04-02 | Novaliq Gmbh | Lipid barrier repair |
| SG11202102820VA (en) | 2018-10-12 | 2021-04-29 | Novaliq Gmbh | Ophthalmic composition for treatment of dry eye disease |
| US20220008397A1 (en) * | 2019-01-21 | 2022-01-13 | Novaliq Gmbh | Pharmaceutical composition for the treatment of ocular neovascularisation |
| CN113710228A (zh) | 2019-02-13 | 2021-11-26 | 诺瓦利克有限责任公司 | 用于治疗眼部新生血管形成的组合物和方法 |
| US12419933B2 (en) | 2019-09-06 | 2025-09-23 | Novaliq Gmbh | Ophthalmic composition for the treatment of uveitis |
| EP4618949A1 (en) * | 2022-11-17 | 2025-09-24 | Martin Coffey | Semifluorinated alkane antibiotic combination compositions for treatment of ocular disorders |
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2010
- 2010-10-20 EP EP10188242A patent/EP2444063A1/en not_active Withdrawn
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2011
- 2011-10-18 JP JP2013534288A patent/JP5770297B2/ja active Active
- 2011-10-18 ES ES11770454.4T patent/ES2528105T3/es active Active
- 2011-10-18 BR BR112013007473-6A patent/BR112013007473B1/pt active IP Right Grant
- 2011-10-18 PL PL11770454T patent/PL2629754T3/pl unknown
- 2011-10-18 CN CN201180049413.3A patent/CN103153281B/zh active Active
- 2011-10-18 CA CA2813016A patent/CA2813016C/en active Active
- 2011-10-18 US US13/824,048 patent/US9757459B2/en active Active
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- 2011-10-18 MX MX2013003892A patent/MX2013003892A/es active IP Right Grant
- 2011-10-18 KR KR1020137009743A patent/KR101773225B1/ko active Active
- 2011-10-18 WO PCT/EP2011/068141 patent/WO2012052418A1/en not_active Ceased
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- 2011-10-18 EP EP11770454.4A patent/EP2629754B1/en active Active
- 2011-10-18 PT PT117704544T patent/PT2629754E/pt unknown
- 2011-10-18 IN IN2524DEN2013 patent/IN2013DN02524A/en unknown
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| IN2013DN02524A (https=) | 2015-08-07 |
| EP2444063A1 (en) | 2012-04-25 |
| JP2013540140A (ja) | 2013-10-31 |
| JP5770297B2 (ja) | 2015-08-26 |
| US20180008710A1 (en) | 2018-01-11 |
| WO2012052418A1 (en) | 2012-04-26 |
| AU2011317673A1 (en) | 2013-04-11 |
| CN103153281A (zh) | 2013-06-12 |
| CA2813016A1 (en) | 2012-04-26 |
| ES2528105T3 (es) | 2015-02-04 |
| BR112013007473A2 (pt) | 2016-07-19 |
| HK1182010A1 (en) | 2013-11-22 |
| CN103153281B (zh) | 2015-09-30 |
| KR20130139925A (ko) | 2013-12-23 |
| BR112013007473B1 (pt) | 2021-11-03 |
| EP2629754B1 (en) | 2014-11-05 |
| US11160865B2 (en) | 2021-11-02 |
| DK2629754T3 (en) | 2015-01-26 |
| US20180221485A1 (en) | 2018-08-09 |
| MX2013003892A (es) | 2013-07-05 |
| US9968678B2 (en) | 2018-05-15 |
| KR101773225B1 (ko) | 2017-09-12 |
| PT2629754E (pt) | 2015-02-04 |
| AU2011317673B2 (en) | 2014-07-17 |
| US9757459B2 (en) | 2017-09-12 |
| PL2629754T3 (pl) | 2015-04-30 |
| US20130266652A1 (en) | 2013-10-10 |
| EP2629754A1 (en) | 2013-08-28 |
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