CA2801309C - Methods and compositions for oral pharmaceutical therapy - Google Patents
Methods and compositions for oral pharmaceutical therapy Download PDFInfo
- Publication number
- CA2801309C CA2801309C CA2801309A CA2801309A CA2801309C CA 2801309 C CA2801309 C CA 2801309C CA 2801309 A CA2801309 A CA 2801309A CA 2801309 A CA2801309 A CA 2801309A CA 2801309 C CA2801309 C CA 2801309C
- Authority
- CA
- Canada
- Prior art keywords
- cancer
- agent
- composition
- use according
- taurolidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35018310P | 2010-06-01 | 2010-06-01 | |
| US61/350,183 | 2010-06-01 | ||
| US37031510P | 2010-08-03 | 2010-08-03 | |
| US61/370,315 | 2010-08-03 | ||
| PCT/IB2011/001539 WO2011151722A2 (en) | 2010-06-01 | 2011-06-01 | Methods and compositions for oral pharmaceutical therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2801309A1 CA2801309A1 (en) | 2011-12-08 |
| CA2801309C true CA2801309C (en) | 2018-07-17 |
Family
ID=45067142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2801309A Active CA2801309C (en) | 2010-06-01 | 2011-06-01 | Methods and compositions for oral pharmaceutical therapy |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9028866B2 (https=) |
| EP (1) | EP2575783B1 (https=) |
| JP (2) | JP5926243B2 (https=) |
| CN (1) | CN103118669B (https=) |
| AU (1) | AU2011262308B2 (https=) |
| BR (1) | BR112012030641B8 (https=) |
| CA (1) | CA2801309C (https=) |
| ES (1) | ES2614878T3 (https=) |
| WO (1) | WO2011151722A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2632248C2 (ru) * | 2012-05-15 | 2017-10-03 | Филипс Лайтинг Холдинг Б.В. | Управление устройствами освещения |
| US20190381060A1 (en) | 2016-01-11 | 2019-12-19 | Cormedix Inc. | Taurolidine treatment for myc-expressing tumors in mammalian bodies |
| EP3402527B1 (en) * | 2016-01-11 | 2022-09-28 | CorMedix Inc. | Therapeutic nanoparticles for the treatment of neuroblastoma and other cancers |
| US11541061B2 (en) | 2016-01-11 | 2023-01-03 | Cormedix Inc. | Neuroblastoma treatment with taurolidine hydrolysis products |
| US20190381058A1 (en) * | 2016-01-11 | 2019-12-19 | Cormedix Inc. | Methods and compositions for treating neuroblastoma in a juvenile mammalian body |
| SI3709979T1 (sl) | 2017-11-17 | 2025-03-31 | Evonik Operations Gmbh | Postopek za pripravo obložene kapsule s trdo ovojnico |
| JP2021535163A (ja) * | 2018-08-28 | 2021-12-16 | コーメディクス・インコーポレーテッド | タウロリジン加水分解産物による神経芽細胞腫治療 |
| CN113226325A (zh) * | 2018-08-31 | 2021-08-06 | 科医公司 | 牛磺罗定对哺乳动物体内表达myc的肿瘤的治疗 |
| WO2020234833A1 (en) | 2019-05-22 | 2020-11-26 | Geistlich Pharma Ag | Method for treating, preventing, inhibiting or reducing cytokine release |
| WO2020234829A1 (en) * | 2019-05-22 | 2020-11-26 | Geistlich Pharma Ag | Methods and compositions for inhibiting gapdh |
| CN111671758A (zh) * | 2020-07-06 | 2020-09-18 | 长春迈灵生物工程有限公司 | 牛磺罗定在制备抗hiv病毒药物中的应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5210083A (en) | 1986-07-17 | 1993-05-11 | Ed. Geistlich Sohne A.G. Fur Chemische Industrie | Pharmaceutical compositions |
| IE66933B1 (en) * | 1990-01-15 | 1996-02-07 | Elan Corp Plc | Controlled absorption naproxen formulation for once-daily administration |
| US20030027818A1 (en) * | 2001-04-03 | 2003-02-06 | Redmond H. Paul | Treatment of cancers |
| US5972933A (en) * | 1998-01-08 | 1999-10-26 | Ed. Geistlich Sohne Ag Fur Chemische Industrie | Method of treating microbial infections |
| US6555534B1 (en) * | 1998-09-11 | 2003-04-29 | Medpointe Healthcare Inc. | Method and compositions for the control or eradication of Helicobacter pylori |
| US6251896B1 (en) * | 1999-03-24 | 2001-06-26 | Carter-Wallace, Inc. | Compositions and methods for the management of Crohn's disease |
| CA2381425A1 (en) * | 1999-08-24 | 2001-03-01 | Cellgate, Inc. | Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties |
| JP5027369B2 (ja) | 1999-12-06 | 2012-09-19 | ガイストリッヒ ファーマ アーゲー | 腫瘍を治療する方法 |
| US20020004502A1 (en) * | 2000-01-05 | 2002-01-10 | Redmond H. Paul | Treatment of inflammatory bowel disease |
| US20040170617A1 (en) * | 2000-06-05 | 2004-09-02 | Finegold Sydney M. | Method of treating diseases associated with abnormal gastrointestinal flora |
| AU779362B2 (en) * | 2000-10-27 | 2005-01-20 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| SK287902B6 (sk) * | 2001-01-31 | 2012-03-02 | Evonik Rohm Gmbh | Multiparticulate drug form and method for the preparation thereof |
| US20030092707A1 (en) * | 2001-10-19 | 2003-05-15 | Redmond H. Paul | Treatment of breast cancer |
| US9138408B2 (en) * | 2002-06-21 | 2015-09-22 | L'oreal | Use of taurine for treating alopecia |
| US20060198886A1 (en) * | 2005-03-01 | 2006-09-07 | Jenkins Richard B | Medicament having coated methenamine combined with acidifier |
| WO2007069272A2 (en) * | 2005-10-21 | 2007-06-21 | Panacea Biotec Limited | Pharmaceutical composition comprising at least one anticancer drug and at least one polymer |
| ES2318628T3 (es) * | 2006-07-25 | 2009-05-01 | Claus Herdeis | Preparacion de formulaciones antimicrobianas que comprenden 7-oxa-2-tia-1,5 diazabiciclo(3.3.1)-nonan-2,2-diona. |
-
2011
- 2011-06-01 CN CN201180036488.8A patent/CN103118669B/zh active Active
- 2011-06-01 BR BR112012030641A patent/BR112012030641B8/pt not_active IP Right Cessation
- 2011-06-01 AU AU2011262308A patent/AU2011262308B2/en active Active
- 2011-06-01 CA CA2801309A patent/CA2801309C/en active Active
- 2011-06-01 ES ES11758551.3T patent/ES2614878T3/es active Active
- 2011-06-01 WO PCT/IB2011/001539 patent/WO2011151722A2/en not_active Ceased
- 2011-06-01 US US13/701,372 patent/US9028866B2/en active Active
- 2011-06-01 JP JP2013513002A patent/JP5926243B2/ja active Active
- 2011-06-01 EP EP11758551.3A patent/EP2575783B1/en active Active
-
2016
- 2016-02-29 JP JP2016037487A patent/JP2016155826A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ES2614878T3 (es) | 2017-06-02 |
| BR112012030641A2 (pt) | 2016-08-16 |
| US9028866B2 (en) | 2015-05-12 |
| BR112012030641B8 (pt) | 2022-06-14 |
| CN103118669A (zh) | 2013-05-22 |
| JP2016155826A (ja) | 2016-09-01 |
| WO2011151722A3 (en) | 2012-05-24 |
| US20130089606A1 (en) | 2013-04-11 |
| AU2011262308A1 (en) | 2013-01-10 |
| CA2801309A1 (en) | 2011-12-08 |
| CN103118669B (zh) | 2016-01-13 |
| WO2011151722A2 (en) | 2011-12-08 |
| BR112012030641B1 (pt) | 2022-05-24 |
| EP2575783A2 (en) | 2013-04-10 |
| AU2011262308B2 (en) | 2014-07-31 |
| JP5926243B2 (ja) | 2016-05-25 |
| JP2013527224A (ja) | 2013-06-27 |
| EP2575783B1 (en) | 2017-01-11 |
| HK1183228A1 (zh) | 2013-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20160415 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 14TH ANNIV.) - STANDARD Year of fee payment: 14 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250520 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250520 |