CA2782902C - Pesticidal bis-organosulfur compounds - Google Patents
Pesticidal bis-organosulfur compounds Download PDFInfo
- Publication number
- CA2782902C CA2782902C CA2782902A CA2782902A CA2782902C CA 2782902 C CA2782902 C CA 2782902C CA 2782902 A CA2782902 A CA 2782902A CA 2782902 A CA2782902 A CA 2782902A CA 2782902 C CA2782902 C CA 2782902C
- Authority
- CA
- Canada
- Prior art keywords
- cf2cf3
- cf2h
- alkyl
- haloalkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
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- 230000000361 pesticidal effect Effects 0.000 title description 7
- 150000003839 salts Chemical class 0.000 claims abstract description 54
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 41
- 241000238421 Arthropoda Species 0.000 claims abstract description 11
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims description 691
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 430
- 150000001875 compounds Chemical class 0.000 claims description 285
- -1 hydroxy, amino Chemical group 0.000 claims description 170
- 239000001257 hydrogen Substances 0.000 claims description 117
- 229910052739 hydrogen Inorganic materials 0.000 claims description 117
- 239000000203 mixture Substances 0.000 claims description 108
- 229910052736 halogen Inorganic materials 0.000 claims description 103
- 150000002367 halogens Chemical group 0.000 claims description 94
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 78
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 70
- 125000001188 haloalkyl group Chemical group 0.000 claims description 65
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims description 60
- 241001465754 Metazoa Species 0.000 claims description 60
- 125000000217 alkyl group Chemical group 0.000 claims description 60
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 50
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 46
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 43
- 238000009472 formulation Methods 0.000 claims description 42
- 229910052717 sulfur Inorganic materials 0.000 claims description 40
- 125000003118 aryl group Chemical group 0.000 claims description 39
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 39
- 125000005347 halocycloalkyl group Chemical group 0.000 claims description 39
- 229910052760 oxygen Inorganic materials 0.000 claims description 39
- 239000001301 oxygen Substances 0.000 claims description 39
- 125000001072 heteroaryl group Chemical group 0.000 claims description 38
- 239000011593 sulfur Chemical group 0.000 claims description 38
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 36
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims description 33
- 238000000034 method Methods 0.000 claims description 33
- 125000005843 halogen group Chemical group 0.000 claims description 32
- 239000000463 material Substances 0.000 claims description 29
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 28
- 125000000392 cycloalkenyl group Chemical group 0.000 claims description 28
- 125000006643 (C2-C6) haloalkenyl group Chemical group 0.000 claims description 27
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims description 27
- 244000045947 parasite Species 0.000 claims description 26
- 125000000623 heterocyclic group Chemical group 0.000 claims description 22
- 206010061217 Infestation Diseases 0.000 claims description 20
- 125000000262 haloalkenyl group Chemical group 0.000 claims description 20
- 125000000232 haloalkynyl group Chemical group 0.000 claims description 20
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims description 19
- 125000003342 alkenyl group Chemical group 0.000 claims description 19
- 125000005842 heteroatom Chemical group 0.000 claims description 19
- 229910052757 nitrogen Chemical group 0.000 claims description 19
- 125000006619 (C1-C6) dialkylamino group Chemical group 0.000 claims description 17
- 125000001424 substituent group Chemical group 0.000 claims description 17
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims description 16
- 125000003282 alkyl amino group Chemical group 0.000 claims description 16
- 125000005366 cycloalkylthio group Chemical group 0.000 claims description 16
- 125000000000 cycloalkoxy group Chemical group 0.000 claims description 15
- 125000004663 dialkyl amino group Chemical group 0.000 claims description 15
- 244000078703 ectoparasite Species 0.000 claims description 15
- 125000006769 halocycloalkoxy group Chemical group 0.000 claims description 15
- 125000000304 alkynyl group Chemical group 0.000 claims description 14
- 125000004465 cycloalkenyloxy group Chemical group 0.000 claims description 14
- 238000011282 treatment Methods 0.000 claims description 14
- 125000004665 trialkylsilyl group Chemical group 0.000 claims description 14
- 125000006766 (C2-C6) alkynyloxy group Chemical group 0.000 claims description 13
- 125000006765 (C2-C6) haloalkenyloxy group Chemical group 0.000 claims description 13
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 125000003320 C2-C6 alkenyloxy group Chemical group 0.000 claims description 12
- 125000003545 alkoxy group Chemical group 0.000 claims description 12
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 12
- 230000003071 parasitic effect Effects 0.000 claims description 12
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- 125000004414 alkyl thio group Chemical group 0.000 claims description 11
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- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims description 10
- 125000004122 cyclic group Chemical group 0.000 claims description 10
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 10
- 125000004995 haloalkylthio group Chemical group 0.000 claims description 10
- 125000002733 (C1-C6) fluoroalkyl group Chemical group 0.000 claims description 8
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- 244000079386 endoparasite Species 0.000 claims description 8
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 claims description 7
- 125000006771 (C1-C6) haloalkylthio group Chemical group 0.000 claims description 7
- 125000004438 haloalkoxy group Chemical group 0.000 claims description 7
- 125000004644 alkyl sulfinyl group Chemical group 0.000 claims description 6
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- 239000005864 Sulphur Chemical group 0.000 claims description 5
- 125000006323 alkenyl amino group Chemical group 0.000 claims description 5
- 125000006319 alkynyl amino group Chemical group 0.000 claims description 5
- 125000005133 alkynyloxy group Chemical group 0.000 claims description 5
- 125000005134 alkynylsulfinyl group Chemical group 0.000 claims description 5
- 125000005139 alkynylsulfonyl group Chemical group 0.000 claims description 5
- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims description 5
- 125000005291 haloalkenyloxy group Chemical group 0.000 claims description 5
- 125000004440 haloalkylsulfinyl group Chemical group 0.000 claims description 5
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 claims description 5
- 125000006767 (C2-C6) haloalkynyloxy group Chemical group 0.000 claims description 4
- 125000005136 alkenylsulfinyl group Chemical group 0.000 claims description 4
- 125000005137 alkenylsulfonyl group Chemical group 0.000 claims description 4
- 125000004104 aryloxy group Chemical group 0.000 claims description 4
- 239000002689 soil Substances 0.000 claims description 4
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims description 3
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 claims description 2
- 125000006799 (C2-C6) alkenylamino group Chemical group 0.000 claims description 2
- 125000006802 (C2-C6) alkynylamino group Chemical group 0.000 claims description 2
- 238000011200 topical administration Methods 0.000 claims description 2
- 150000002431 hydrogen Chemical group 0.000 claims 13
- 125000004641 (C1-C12) haloalkyl group Chemical group 0.000 claims 1
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 claims 1
- 125000004749 (C1-C6) haloalkylsulfinyl group Chemical group 0.000 claims 1
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims 1
- 125000005103 alkyl silyl group Chemical group 0.000 claims 1
- 125000006340 pentafluoro ethyl group Chemical group FC(F)(F)C(F)(F)* 0.000 description 508
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 description 171
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 description 78
- 125000006341 heptafluoro n-propyl group Chemical group FC(F)(F)C(F)(F)C(F)(F)* 0.000 description 61
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 20
- 238000002425 crystallisation Methods 0.000 description 19
- 230000008025 crystallization Effects 0.000 description 19
- 241000255925 Diptera Species 0.000 description 18
- 239000003112 inhibitor Substances 0.000 description 18
- 241000238876 Acari Species 0.000 description 16
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 15
- 229920001223 polyethylene glycol Polymers 0.000 description 15
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 14
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- 150000002148 esters Chemical class 0.000 description 13
- 208000015181 infectious disease Diseases 0.000 description 13
- 239000003960 organic solvent Substances 0.000 description 13
- 239000004094 surface-active agent Substances 0.000 description 13
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 12
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 11
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- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 229960004418 trolamine Drugs 0.000 description 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 description 1
- 239000000273 veterinary drug Substances 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
- 238000010626 work up procedure Methods 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
- 150000003738 xylenes Chemical class 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011592 zinc chloride Substances 0.000 description 1
- 235000005074 zinc chloride Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/65—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfone or sulfoxide groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/10—Sulfones; Sulfoxides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/40—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C327/42—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Catching Or Destruction (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Farming Of Fish And Shellfish (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26675509P | 2009-12-04 | 2009-12-04 | |
| US61/266,755 | 2009-12-04 | ||
| PCT/US2010/059011 WO2011069143A1 (en) | 2009-12-04 | 2010-12-05 | Pesticidal bis-organosulfur compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2782902A1 CA2782902A1 (en) | 2011-06-09 |
| CA2782902C true CA2782902C (en) | 2017-10-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2782902A Active CA2782902C (en) | 2009-12-04 | 2010-12-05 | Pesticidal bis-organosulfur compounds |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8846569B2 (enExample) |
| EP (1) | EP2507209B1 (enExample) |
| JP (1) | JP5780681B2 (enExample) |
| CN (1) | CN102712583B (enExample) |
| AU (1) | AU2010325827B2 (enExample) |
| BR (1) | BR112012013482B1 (enExample) |
| CA (1) | CA2782902C (enExample) |
| ES (1) | ES2546100T3 (enExample) |
| MX (1) | MX2012006366A (enExample) |
| NZ (1) | NZ600252A (enExample) |
| WO (1) | WO2011069143A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2793481T3 (es) | 2010-09-24 | 2020-11-16 | Zoetis Services Llc | Oximas de isoxazolina como agentes antiparasitarios |
| US10806123B2 (en) * | 2015-12-28 | 2020-10-20 | Boehringer Ingelheim Animal Health USA Inc. | Methods of providing grass growth and nematode suitability indices to assist determination of timing of parasiticide treatment |
| UA129046C2 (uk) * | 2015-12-28 | 2025-01-01 | Новонесіс Плант Біосолушнз А/С | Неводна композиція з інокулянтом |
| AR112780A1 (es) * | 2017-08-08 | 2019-12-11 | Valent Biosciences Llc | Formulaciones granuladas de rizobios y micorrizas y sus mezclas |
| TWI799494B (zh) | 2018-01-19 | 2023-04-21 | 荷蘭商Asm 智慧財產控股公司 | 沈積方法 |
| CN108276351A (zh) * | 2018-02-11 | 2018-07-13 | 天津大学 | 具有潜在抗癌效果化合物及其测定方法 |
| CN116849231A (zh) * | 2018-05-15 | 2023-10-10 | 旗舰创业创新六公司 | 有害生物防治组合物及其用途 |
| AR116016A1 (es) | 2018-08-24 | 2021-03-25 | Flagship Pioneering Innovations Vi Llc | Métodos para fabricar paquetes mensajeros vegetales |
| WO2020049584A1 (en) * | 2018-09-03 | 2020-03-12 | Parijat Industries (India) Private Limited | A synergistic pesticidal wettable granule formulation comprising emamectin benzoate and profenofos |
| MX2022005901A (es) * | 2019-11-15 | 2022-09-02 | New Life Crop Sciences Llc | Composiciones y métodos para el tratamiento de la enfermedad de huanglongbing en cítricos. |
Family Cites Families (133)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2753377B1 (fr) | 1996-09-19 | 1999-09-24 | Rhone Merieux | Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides |
| US6426333B1 (en) | 1996-09-19 | 2002-07-30 | Merial | Spot-on formulations for combating parasites |
| US2872458A (en) * | 1954-12-30 | 1959-02-03 | Merck & Co Inc | Addition product of a metal hydrocarbon mercaptide with an alpha-halogamma-butyrolactone |
| US3060084A (en) | 1961-06-09 | 1962-10-23 | Du Pont | Improved homogeneous, readily dispersed, pesticidal concentrate |
| US3299566A (en) | 1964-06-01 | 1967-01-24 | Olin Mathieson | Water soluble film containing agricultural chemicals |
| US4144050A (en) | 1969-02-05 | 1979-03-13 | Hoechst Aktiengesellschaft | Micro granules for pesticides and process for their manufacture |
| NL160809C (nl) | 1970-05-15 | 1979-12-17 | Duphar Int Res | Werkwijze ter bereiding van benzoylureumverbindingen, alsmede werkwijze ter bereiding van insekticide prepara- ten op basis van benzoylureumverbindingen. |
| US3950360A (en) | 1972-06-08 | 1976-04-13 | Sankyo Company Limited | Antibiotic substances |
| JPS4914624A (enExample) | 1972-06-08 | 1974-02-08 | ||
| US3818047A (en) | 1972-08-07 | 1974-06-18 | C Henrick | Substituted pyrones |
| US3920442A (en) | 1972-09-18 | 1975-11-18 | Du Pont | Water-dispersible pesticide aggregates |
| US4036970A (en) * | 1975-07-28 | 1977-07-19 | Syntex (U.S.A.) Inc. | Imidazol-1-yl propane derivatives |
| SE434277B (sv) | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| CH604517A5 (enExample) | 1976-08-19 | 1978-09-15 | Ciba Geigy Ag | |
| US4172714A (en) | 1976-12-20 | 1979-10-30 | E. I. Du Pont De Nemours And Company | Dry compactible, swellable herbicidal compositions and pellets produced therefrom |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4134973A (en) | 1977-04-11 | 1979-01-16 | Merck & Co., Inc. | Carbohydrate derivatives of milbemycin and processes therefor |
| US4199569A (en) | 1977-10-03 | 1980-04-22 | Merck & Co., Inc. | Selective hydrogenation products of C-076 compounds and derivatives thereof |
| US4144352A (en) | 1977-12-19 | 1979-03-13 | Merck & Co., Inc. | Milbemycin compounds as anthelmintic agents |
| US4203976A (en) | 1978-08-02 | 1980-05-20 | Merck & Co., Inc. | Sugar derivatives of C-076 compounds |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| JPS57139012A (en) | 1981-02-23 | 1982-08-27 | Sankyo Co Ltd | Anthelmintic composition |
| GB2095558B (en) | 1981-03-30 | 1984-10-24 | Avon Packers Ltd | Formulation of agricultural chemicals |
| US4427663A (en) | 1982-03-16 | 1984-01-24 | Merck & Co., Inc. | 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof |
| DE3235931A1 (de) | 1982-09-29 | 1984-03-29 | Bayer Ag, 5090 Leverkusen | Koeder zur bekaempfung von ungeziefer |
| JPS59199673A (ja) | 1983-04-25 | 1984-11-12 | Sumitomo Chem Co Ltd | 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤 |
| BR8404834A (pt) | 1983-09-26 | 1985-08-13 | Agrigenetics Res Ass | Metodo para modificar geneticamente uma celula vegetal |
| US5304732A (en) | 1984-03-06 | 1994-04-19 | Mgi Pharma, Inc. | Herbicide resistance in plants |
| EP0179022B1 (de) | 1984-10-18 | 1990-11-07 | Ciba-Geigy Ag | Benzoylphenylharnstoffe |
| BR8600161A (pt) | 1985-01-18 | 1986-09-23 | Plant Genetic Systems Nv | Gene quimerico,vetores de plasmidio hibrido,intermediario,processo para controlar insetos em agricultura ou horticultura,composicao inseticida,processo para transformar celulas de plantas para expressar uma toxina de polipeptideo produzida por bacillus thuringiensis,planta,semente de planta,cultura de celulas e plasmidio |
| ATE67493T1 (de) | 1985-02-04 | 1991-10-15 | Bayer Agrochem Kk | Heterocyclische verbindungen. |
| EP0237482A1 (de) | 1986-03-06 | 1987-09-16 | Ciba-Geigy Ag | C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen |
| ATE57390T1 (de) | 1986-03-11 | 1990-10-15 | Plant Genetic Systems Nv | Durch gentechnologie erhaltene und gegen glutaminsynthetase-inhibitoren resistente pflanzenzellen. |
| EP0246739B1 (en) | 1986-03-25 | 1991-01-23 | Sankyo Company Limited | Macrolide compounds, their preparation and their use |
| EP0252879B1 (de) | 1986-07-02 | 1992-05-06 | Ciba-Geigy Ag | Pestizide |
| US5013659A (en) | 1987-07-27 | 1991-05-07 | E. I. Du Pont De Nemours And Company | Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase |
| IL83348A (en) | 1986-08-26 | 1995-12-08 | Du Pont | Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase |
| US4855317A (en) | 1987-03-06 | 1989-08-08 | Ciba-Geigy Corporation | Insecticides and parasiticides |
| US4871719A (en) | 1987-03-24 | 1989-10-03 | Ciba-Geigy Corporation | Composition for controlling parasites in productive livestock |
| JPS6452771A (en) * | 1987-05-29 | 1989-02-28 | Takeda Chemical Industries Ltd | Amino-containing 1,3-dithian compound and insecticidal and acaricidal composition containing said compound |
| US4874749A (en) | 1987-07-31 | 1989-10-17 | Merck & Co., Inc. | 4"-Deoxy-4-N-methylamino avermectin Bla/Blb |
| DE3888936T2 (de) | 1987-11-03 | 1994-07-21 | Beecham Group Plc | Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung. |
| FR2629098B1 (fr) | 1988-03-23 | 1990-08-10 | Rhone Poulenc Agrochimie | Gene chimerique de resistance herbicide |
| KR900003088B1 (ko) | 1988-03-26 | 1990-05-07 | 재단법인 한국화학연구소 | 5-하이드록시피라졸 유도체 |
| US5180587A (en) | 1988-06-28 | 1993-01-19 | E. I. Du Pont De Nemours And Company | Tablet formulations of pesticides |
| US4938389A (en) | 1988-11-03 | 1990-07-03 | Eye Research Institute Of Retina Foundation | Filter bottle |
| NZ231804A (en) | 1988-12-19 | 1993-03-26 | Ciba Geigy Ag | Insecticidal toxin from leiurus quinquestriatus hebraeus |
| NZ232422A (en) | 1989-02-16 | 1992-11-25 | Merck & Co Inc | 13-ketal milbemycin derivatives and parasiticides |
| ES2199931T3 (es) | 1989-03-24 | 2004-03-01 | Syngenta Participations Ag | Plantas transgenicas resistentes a enfermedades. |
| DK0415688T3 (da) | 1989-08-30 | 1999-08-23 | Aeci Ltd | Fremgangsmåde til fremstilling af et doseringssystem samt fremgangsmåde til behandling af en genstand eller et locus |
| DK0427529T3 (da) | 1989-11-07 | 1995-06-26 | Pioneer Hi Bred Int | Larvedræbende lactiner og planteinsektresistens baseret derpå |
| IE904606A1 (en) | 1989-12-21 | 1991-07-03 | Beecham Group Plc | Novel products |
| PL167613B1 (pl) | 1990-03-12 | 1995-09-30 | Du Pont | Granulowana kompozycja rozpuszczalna lub dyspergowalna w wodzie PL |
| DE69133261D1 (de) | 1990-03-16 | 2003-06-26 | Calgene Llc Davis | Dnas, die für pflanzliche desaturasen kodieren und deren anwendungen |
| RU2148081C1 (ru) | 1990-06-18 | 2000-04-27 | Монсанто Компани | Способ получения генетически трансформированных растений с повышенным содержанием крахмала и рекомбинантная двухцепочечная днк-молекула |
| ES2173077T3 (es) | 1990-06-25 | 2002-10-16 | Monsanto Technology Llc | Plantas que toleran glifosato. |
| EP0480679B1 (en) | 1990-10-11 | 1996-09-18 | Sumitomo Chemical Company Limited | Pesticidal composition |
| SE467358B (sv) | 1990-12-21 | 1992-07-06 | Amylogene Hb | Genteknisk foeraendring av potatis foer bildning av staerkelse av amylopektintyp |
| NZ247278A (en) | 1991-02-12 | 1995-03-28 | Ancare Distributors | Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier |
| DE4104782B4 (de) | 1991-02-13 | 2006-05-11 | Bayer Cropscience Gmbh | Neue Plasmide, enthaltend DNA-Sequenzen, die Veränderungen der Karbohydratkonzentration und Karbohydratzusammensetzung in Pflanzen hervorrufen, sowie Pflanzen und Pflanzenzellen enthaltend dieses Plasmide |
| WO1992022555A1 (en) | 1991-06-17 | 1992-12-23 | Beecham Group Plc | Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents |
| UA48104C2 (uk) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника |
| US5345377A (en) | 1992-10-30 | 1994-09-06 | Electric Power Research Institute, Inc. | Harmonic controller for an active power line conditioner |
| GB9300883D0 (en) | 1993-01-18 | 1993-03-10 | Pfizer Ltd | Antiparasitic agents |
| DE4322211A1 (de) | 1993-07-03 | 1995-01-12 | Basf Ag | Wäßrige, mehrphasige, stabile Fertigformulierung für Pflanzenschutz-Wirkstoffe und Verfahren zu ihrer Herstellung |
| US5399582A (en) | 1993-11-01 | 1995-03-21 | Merck & Co., Inc. | Antiparasitic agents |
| US5530195A (en) | 1994-06-10 | 1996-06-25 | Ciba-Geigy Corporation | Bacillus thuringiensis gene encoding a toxin active against insects |
| AUPM969994A0 (en) | 1994-11-28 | 1994-12-22 | Virbac S.A. | Equine anthelmintic formulations |
| US6221894B1 (en) | 1995-03-20 | 2001-04-24 | Merck & Co., Inc. | Nodulisporic acid derivatives |
| US5962499A (en) | 1995-03-20 | 1999-10-05 | Merck & Co., Inc. | Nodulisporic acid derivatives |
| JPH0931049A (ja) * | 1995-07-20 | 1997-02-04 | Matsushita Electric Ind Co Ltd | フロロアルキルカルボン酸とその誘導体 |
| TW334436B (en) | 1995-07-21 | 1998-06-21 | Upjohn Co | Antiparasitic marcfortines and paraherquamides |
| FR2739255B1 (fr) | 1995-09-29 | 1998-09-04 | Rhone Merieux | Composition antiparasitaire pour le traitement et la protection des animaux de compagnie |
| IE80657B1 (en) | 1996-03-29 | 1998-11-04 | Merial Sas | Insecticidal combination to control mammal fleas in particular fleas on cats and dogs |
| FR2752525B1 (fr) | 1996-08-20 | 2000-05-05 | Rhone Merieux | Procede de lutte contre les myiases des cheptels bovins et ovins et compositions pour la mise en oeuvre de ce procede |
| US6010710A (en) | 1996-03-29 | 2000-01-04 | Merial | Direct pour-on skin solution for antiparasitic use in cattle and sheep |
| US5885607A (en) | 1996-03-29 | 1999-03-23 | Rhone Merieux | N-phenylpyrazole-based anti-flea and anti-tick external device for cats and dogs |
| DE19613334A1 (de) | 1996-04-03 | 1997-10-09 | Bayer Ag | Mittel zur Bekämpfung parasitierender Insekten und Milben an Menschen |
| US5773704A (en) | 1996-04-29 | 1998-06-30 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Herbicide resistant rice |
| US5773702A (en) | 1996-07-17 | 1998-06-30 | Board Of Trustees Operating Michigan State University | Imidazolinone herbicide resistant sugar beet plants |
| AU3596697A (en) | 1996-07-17 | 1998-02-09 | Michigan State University | Imidazolinone herbicide resistant sugar beet plants |
| US6998131B2 (en) | 1996-09-19 | 2006-02-14 | Merial Limited | Spot-on formulations for combating parasites |
| US6207647B1 (en) | 1997-07-18 | 2001-03-27 | Smithkline Beecham Corporation | RatA |
| US6174540B1 (en) | 1998-09-14 | 2001-01-16 | Merck & Co., Inc. | Long acting injectable formulations containing hydrogenated caster oil |
| US6348643B1 (en) | 1998-10-29 | 2002-02-19 | American Cyanamid Company | DNA sequences encoding the arabidopsis acetohydroxy-acid synthase small subunit and methods of use |
| US6787342B2 (en) | 2000-02-16 | 2004-09-07 | Merial Limited | Paste formulations |
| PE20011289A1 (es) | 2000-04-07 | 2001-12-21 | Upjohn Co | Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles |
| MX233208B (es) | 2000-04-28 | 2005-12-20 | Basf Ag | Uso del gen mutante ahas 2 del maiz xi12 y herbicidas de imidazolinona para la seleccion de plantas de maiz, arroz y trigo, monocotiledoneas transgenicas, resistentes a los herbicidas de imidazolinona. |
| US6399786B1 (en) | 2000-07-14 | 2002-06-04 | Merck & Co., Inc. | Nonacyclic nodulisporic acid derivatives |
| DE60111236T2 (de) | 2000-08-25 | 2006-04-27 | Syngenta Participations Ag | Hybriden von crystal proteinen aus bacillus thurigiensis |
| JP4269574B2 (ja) | 2001-05-09 | 2009-05-27 | 住友化学株式会社 | マロノニトリル化合物及びその用途 |
| AR036336A1 (es) | 2001-08-09 | 2004-09-01 | Univ Saskatchewan | Una planta de trigo que comprende acidos nucleicos, una parte de planta, una celula de planta., una semilla producida por la planta, un acido nucleico imi aislado, un metodo para controlar las malezas, un metodo para modificar la tolerancia de las plantas y un metodo para producir una planta transge |
| WO2003013225A2 (en) | 2001-08-09 | 2003-02-20 | Northwest Plant Breeding Company | Wheat plants having increased resistance to imidazolinone herbicides |
| UA89016C2 (ru) | 2001-08-09 | 2009-12-25 | Юниверсити Оф Саскачеван | Растение пшеницы с повышенной резистентностью к имидазолиноновым гербицидам |
| US7230167B2 (en) | 2001-08-31 | 2007-06-12 | Syngenta Participations Ag | Modified Cry3A toxins and nucleic acid sequences coding therefor |
| AR037856A1 (es) | 2001-12-17 | 2004-12-09 | Syngenta Participations Ag | Evento de maiz |
| US7001889B2 (en) | 2002-06-21 | 2006-02-21 | Merial Limited | Anthelmintic oral homogeneous veterinary pastes |
| EP1551218B1 (en) | 2002-07-10 | 2017-05-17 | The Department of Agriculture, Western Australia | Wheat plants having increased resistance to imidazolinone herbicides |
| ATE345683T1 (de) | 2002-07-17 | 2006-12-15 | Sumitomo Chemical Co | Malonsäuerenitril-verbindungen und ihre verwendung als pestizide |
| AR042420A1 (es) | 2002-09-11 | 2005-06-22 | Novartis Ag | Benzotriazolil- aminoacetonitril compuestos, proceso para su preparacion, metodo y uso de los mismos en el control de endo- y ecto-parasitos dentro y sobre ganado productor de sangre caliente y animales domesticos y plantas, y en la preparacion de una composicion farmaceutica |
| RU2425152C2 (ru) | 2003-05-28 | 2011-07-27 | Басф Акциенгезельшафт | Растения пшеницы с повышенной толерантностью к имидазолиноновым гербицидам |
| UY28495A1 (es) | 2003-08-29 | 2005-03-31 | Inst Nac De Tecnologia Agropec | Plantas de arroz que tienen una mayor tolerancia a los herbicidas de imidazolinona |
| KR101121944B1 (ko) | 2003-12-26 | 2012-07-12 | 스미또모 가가꾸 가부시끼가이샤 | 니트릴 화합물 및 해충 방제를 위한 이의 용도 |
| EP1704143B1 (en) | 2004-01-16 | 2008-09-03 | Sumitomo Chemical Company, Limited | Malononitrile compound as pesticides |
| CN101538243B (zh) | 2004-01-16 | 2012-05-09 | 住友化学株式会社 | 丙二腈化合物及其用途 |
| CN102558082B (zh) | 2004-03-05 | 2015-09-30 | 日产化学工业株式会社 | 异噁唑啉取代苯甲酰胺化合物的制备中间体 |
| JP2006131529A (ja) | 2004-11-05 | 2006-05-25 | Sumitomo Chemical Co Ltd | 有害生物防除組成物 |
| ES2443690T3 (es) | 2005-09-02 | 2014-02-20 | Nissan Chemical Industries, Ltd. | Compuesto de benzamida sustituido con isoxazolina y agente controlador de organismos dañinos |
| KR101315574B1 (ko) | 2005-10-14 | 2013-10-08 | 스미또모 가가꾸 가부시끼가이샤 | 히드라지드 화합물 및 이의 살충 용도 |
| AU2006317486B9 (en) | 2005-11-22 | 2011-08-04 | Sumitomo Chemical Company, Limited | Organic sulfur compounds and use thereof as arthropodicides |
| JP2007161617A (ja) | 2005-12-12 | 2007-06-28 | Sumitomo Chemical Co Ltd | 有害節足動物防除剤及び有害節足動物の防除方法 |
| JP2007186494A (ja) | 2005-12-15 | 2007-07-26 | Sumitomo Chemical Co Ltd | 含硫黄フルオロアルカン化合物及びその用途 |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
| DE102006015197A1 (de) | 2006-03-06 | 2007-09-13 | Bayer Cropscience Ag | Wirkstoffkombination mit insektiziden Eigenschaften |
| DE102006015467A1 (de) | 2006-03-31 | 2007-10-04 | Bayer Cropscience Ag | Substituierte Enaminocarbonylverbindungen |
| KR101440162B1 (ko) | 2006-06-22 | 2014-09-12 | 바스프 에스이 | 말로노니트릴 화합물 |
| US20080073557A1 (en) | 2006-07-26 | 2008-03-27 | John German | Methods and apparatuses for directing an ion beam source |
| JP5269609B2 (ja) | 2006-11-30 | 2013-08-21 | Meiji Seikaファルマ株式会社 | 害虫防除剤 |
| JP5449669B2 (ja) | 2006-12-14 | 2014-03-19 | 石原産業株式会社 | 有害生物防除組成物 |
| JP2009001541A (ja) | 2006-12-15 | 2009-01-08 | Ishihara Sangyo Kaisha Ltd | 新規ピラゾール化合物を中間体として用いるアントラニルアミド系化合物の製造方法 |
| EP2119361B1 (en) | 2007-03-08 | 2013-10-09 | Meiji Seika Pharma Co., Ltd. | Pest control composition |
| JP2008115155A (ja) | 2007-04-06 | 2008-05-22 | Nippon Soda Co Ltd | 有害生物防除剤組成物及び有害生物防除方法 |
| TW200904329A (en) | 2007-05-18 | 2009-02-01 | Sumitomo Chemical Co | Organic sulfur compound and its use for controlling harmful arthropod |
| JP2009001551A (ja) | 2007-05-18 | 2009-01-08 | Sumitomo Chemical Co Ltd | 有機硫黄化合物及びその有害節足動物防除用途 |
| JP5298631B2 (ja) | 2007-05-18 | 2013-09-25 | 住友化学株式会社 | 有機硫黄化合物及びその有害節足動物防除用途 |
| TW200911745A (en) | 2007-06-29 | 2009-03-16 | Sumitomo Chemical Co | Halogen-containing organosulfur compound and use thereof |
| PL2170321T3 (pl) | 2007-06-29 | 2013-12-31 | Zoetis Services Llc | Połączenie przeciwrobacze |
| TW200911746A (en) | 2007-07-26 | 2009-03-16 | Sumitomo Chemical Co | Fluorine-containing organosulfur compound and pesticidal composition comprising the same |
| JP5287033B2 (ja) | 2007-08-23 | 2013-09-11 | 住友化学株式会社 | 含フッ素有機硫黄化合物およびその有害節足動物防除剤 |
| WO2009051956A2 (en) | 2007-10-16 | 2009-04-23 | E. I. Du Pont De Nemours And Company | Pyrazole-substituted isoxazoline insecticides |
| TWI518076B (zh) | 2008-04-09 | 2016-01-21 | 杜邦股份有限公司 | 製備雜環化合物之方法 |
| JP2010168362A (ja) * | 2008-12-24 | 2010-08-05 | Sumitomo Chemical Co Ltd | 含硫黄化合物およびその用途 |
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- 2010-12-05 ES ES10787664.1T patent/ES2546100T3/es active Active
- 2010-12-05 CA CA2782902A patent/CA2782902C/en active Active
- 2010-12-05 JP JP2012542235A patent/JP5780681B2/ja active Active
- 2010-12-05 US US13/511,736 patent/US8846569B2/en active Active
- 2010-12-05 AU AU2010325827A patent/AU2010325827B2/en active Active
- 2010-12-05 CN CN201080061124.0A patent/CN102712583B/zh active Active
- 2010-12-05 BR BR112012013482-5A patent/BR112012013482B1/pt active IP Right Grant
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Also Published As
| Publication number | Publication date |
|---|---|
| JP5780681B2 (ja) | 2015-09-16 |
| EP2507209A1 (en) | 2012-10-10 |
| NZ600252A (en) | 2014-03-28 |
| CN102712583A (zh) | 2012-10-03 |
| AU2010325827A1 (en) | 2012-06-21 |
| BR112012013482B1 (pt) | 2018-11-06 |
| US8846569B2 (en) | 2014-09-30 |
| ES2546100T3 (es) | 2015-09-18 |
| JP2013512929A (ja) | 2013-04-18 |
| MX2012006366A (es) | 2012-06-27 |
| US20120283094A1 (en) | 2012-11-08 |
| AU2010325827B2 (en) | 2015-11-05 |
| BR112012013482A2 (pt) | 2017-07-25 |
| WO2011069143A1 (en) | 2011-06-09 |
| CA2782902A1 (en) | 2011-06-09 |
| EP2507209B1 (en) | 2015-07-08 |
| CN102712583B (zh) | 2015-04-08 |
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