CA2768081A1 - Anti-influenza agents - Google Patents

Anti-influenza agents Download PDF

Info

Publication number
CA2768081A1
CA2768081A1 CA2768081A CA2768081A CA2768081A1 CA 2768081 A1 CA2768081 A1 CA 2768081A1 CA 2768081 A CA2768081 A CA 2768081A CA 2768081 A CA2768081 A CA 2768081A CA 2768081 A1 CA2768081 A1 CA 2768081A1
Authority
CA
Canada
Prior art keywords
optionally substituted
dideoxy
acetamido
glycero
anhydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2768081A
Other languages
English (en)
French (fr)
Inventor
Mark Von Itzstein
Jeffrey Clifford Dyason
Robin Thomson
Santosh Rudrawar
Mauro Pascolutti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Griffith University
Original Assignee
Griffith University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009903329A external-priority patent/AU2009903329A0/en
Application filed by Griffith University filed Critical Griffith University
Publication of CA2768081A1 publication Critical patent/CA2768081A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA2768081A 2009-07-16 2010-07-16 Anti-influenza agents Abandoned CA2768081A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2009903329A AU2009903329A0 (en) 2009-07-16 Anti-influenza agents
AU2009903329 2009-07-16
PCT/AU2010/000905 WO2011006208A1 (en) 2009-07-16 2010-07-16 Anti -influenza agents

Publications (1)

Publication Number Publication Date
CA2768081A1 true CA2768081A1 (en) 2011-01-20

Family

ID=43448806

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2768081A Abandoned CA2768081A1 (en) 2009-07-16 2010-07-16 Anti-influenza agents

Country Status (11)

Country Link
US (1) US20120202877A1 (enExample)
EP (1) EP2454248A4 (enExample)
JP (1) JP2012532894A (enExample)
CN (1) CN102612514B (enExample)
AU (1) AU2010273184B2 (enExample)
CA (1) CA2768081A1 (enExample)
IL (1) IL217523A0 (enExample)
MX (1) MX2012000576A (enExample)
RU (1) RU2012105073A (enExample)
SG (1) SG177633A1 (enExample)
WO (1) WO2011006208A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9788539B2 (en) 2011-05-17 2017-10-17 Velico Medical, Inc. Platelet protection solution having beta-galactosidase and sialidase inhibitors
EP2903430A1 (en) 2012-10-05 2015-08-12 Velico Medical, Inc. Platelet additive solution having a beta-galactosidase inhibitor
JP6453050B2 (ja) * 2013-11-15 2019-01-16 国立大学法人富山大学 ２−デオキシ−２，３−ジデヒドロシアル酸誘導体およびその製造法
JP6786095B2 (ja) * 2016-07-27 2020-11-18 国立研究開発法人理化学研究所 シアル酸類縁体
US11773129B2 (en) 2017-05-25 2023-10-03 The Governors Of The University Of Alberta Methods of preventing or treating atherosclerosis with inhibitors of specific isoenzymes of human neuraminidase
JP2022543006A (ja) * 2019-07-30 2022-10-07 グリフィス・ユニバーシティ 抗ウイルス剤およびその使用
US12116382B2 (en) 2022-11-28 2024-10-15 Hongene Biotech Corporation Functionalized N-acetylgalactosamine analogs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK282950B6 (sk) * 1990-04-24 2003-01-09 Biota Scientific Management Pty Ltd Deriváty alfa-D-neuramínovej kyseliny, spôsob ich prípravy, ich použitie a farmaceutické prípravky na ich báze
JPH11279168A (ja) * 1996-07-22 1999-10-12 Sankyo Co Ltd ノイラミン酸誘導体
EP0882721A4 (en) * 1996-09-10 1999-12-22 Daikin Ind Ltd SIALIC ACIDS 2,7-DIDEOXY-7-FLUORO- 2, 3-DIDEHYDRO A QUADRUPLE SUBSTITUTION
AUPR001000A0 (en) * 2000-09-08 2000-10-05 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
US7045535B2 (en) * 2001-03-08 2006-05-16 Biocryst Pharmaceuticals, Inc. Compounds useful for inhibiting paramyxovirus neuraminidase

Also Published As

Publication number Publication date
EP2454248A1 (en) 2012-05-23
MX2012000576A (es) 2012-07-20
AU2010273184A1 (en) 2012-03-01
SG177633A1 (en) 2012-02-28
WO2011006208A1 (en) 2011-01-20
US20120202877A1 (en) 2012-08-09
RU2012105073A (ru) 2013-08-27
AU2010273184B2 (en) 2015-07-09
CN102612514A (zh) 2012-07-25
IL217523A0 (en) 2012-02-29
EP2454248A4 (en) 2013-04-03
JP2012532894A (ja) 2012-12-20
CN102612514B (zh) 2016-01-13

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150710

FZDE Discontinued

Effective date: 20170718