AU2010273184B2 - Anti -influenza agents - Google Patents

Anti -influenza agents Download PDF

Info

Publication number
AU2010273184B2
AU2010273184B2 AU2010273184A AU2010273184A AU2010273184B2 AU 2010273184 B2 AU2010273184 B2 AU 2010273184B2 AU 2010273184 A AU2010273184 A AU 2010273184A AU 2010273184 A AU2010273184 A AU 2010273184A AU 2010273184 B2 AU2010273184 B2 AU 2010273184B2
Authority
AU
Australia
Prior art keywords
optionally substituted
alkenyl
dideoxy
acetamido
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2010273184A
Other languages
English (en)
Other versions
AU2010273184A1 (en
Inventor
Jeffrey Clifford Dyason
Mauro Pascolutti
Santosh Rudrawar
Robin Thomson
Mark Von Itzstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Griffith University
Original Assignee
Griffith University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009903329A external-priority patent/AU2009903329A0/en
Application filed by Griffith University filed Critical Griffith University
Priority to AU2010273184A priority Critical patent/AU2010273184B2/en
Publication of AU2010273184A1 publication Critical patent/AU2010273184A1/en
Application granted granted Critical
Publication of AU2010273184B2 publication Critical patent/AU2010273184B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2010273184A 2009-07-16 2010-07-16 Anti -influenza agents Ceased AU2010273184B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2010273184A AU2010273184B2 (en) 2009-07-16 2010-07-16 Anti -influenza agents

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2009903329A AU2009903329A0 (en) 2009-07-16 Anti-influenza agents
AU2009903329 2009-07-16
PCT/AU2010/000905 WO2011006208A1 (en) 2009-07-16 2010-07-16 Anti -influenza agents
AU2010273184A AU2010273184B2 (en) 2009-07-16 2010-07-16 Anti -influenza agents

Publications (2)

Publication Number Publication Date
AU2010273184A1 AU2010273184A1 (en) 2012-03-01
AU2010273184B2 true AU2010273184B2 (en) 2015-07-09

Family

ID=43448806

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010273184A Ceased AU2010273184B2 (en) 2009-07-16 2010-07-16 Anti -influenza agents

Country Status (11)

Country Link
US (1) US20120202877A1 (enExample)
EP (1) EP2454248A4 (enExample)
JP (1) JP2012532894A (enExample)
CN (1) CN102612514B (enExample)
AU (1) AU2010273184B2 (enExample)
CA (1) CA2768081A1 (enExample)
IL (1) IL217523A0 (enExample)
MX (1) MX2012000576A (enExample)
RU (1) RU2012105073A (enExample)
SG (1) SG177633A1 (enExample)
WO (1) WO2011006208A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9788539B2 (en) 2011-05-17 2017-10-17 Velico Medical, Inc. Platelet protection solution having beta-galactosidase and sialidase inhibitors
EP2903430A1 (en) 2012-10-05 2015-08-12 Velico Medical, Inc. Platelet additive solution having a beta-galactosidase inhibitor
JP6453050B2 (ja) * 2013-11-15 2019-01-16 国立大学法人富山大学 ２−デオキシ−２，３−ジデヒドロシアル酸誘導体およびその製造法
JP6786095B2 (ja) * 2016-07-27 2020-11-18 国立研究開発法人理化学研究所 シアル酸類縁体
US11773129B2 (en) 2017-05-25 2023-10-03 The Governors Of The University Of Alberta Methods of preventing or treating atherosclerosis with inhibitors of specific isoenzymes of human neuraminidase
CA3148756A1 (en) * 2019-07-30 2021-02-04 Griffith University Antiviral agents and uses thereof
WO2024118503A1 (en) 2022-11-28 2024-06-06 Hongene Biotech Corporation Functionalized n-acetylgalactosamine analogs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991016320A1 (en) * 1990-04-24 1991-10-31 Biota Scientific Management Pty Ltd Derivatives and analogues of 2-deoxy-2,3-didehydro-n-acetyl neuraminic acid and their use as antiviral agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11279168A (ja) * 1996-07-22 1999-10-12 Sankyo Co Ltd ノイラミン酸誘導体
AU711845B2 (en) * 1996-09-10 1999-10-21 Daikin Industries, Ltd. 4-substituted-2,7-dideoxy-7-fluoro-2,3-didehydro-sialic acid compounds
AUPR001000A0 (en) * 2000-09-08 2000-10-05 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
WO2002076971A1 (en) * 2001-03-08 2002-10-03 Biocryst Pharmaceuticals, Inc. Compounds useful for inhibiting paramyxovirus neuraminidase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991016320A1 (en) * 1990-04-24 1991-10-31 Biota Scientific Management Pty Ltd Derivatives and analogues of 2-deoxy-2,3-didehydro-n-acetyl neuraminic acid and their use as antiviral agents

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GARCiA-SOSA, A. T. et al. J. Chem. Inf. Model. (2008) Vol. 48, pages 2074-2080. *
RUSSELL, R. J. et al. The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature .(2006) Vol. 443, pages 45-49. *

Also Published As

Publication number Publication date
IL217523A0 (en) 2012-02-29
CN102612514A (zh) 2012-07-25
MX2012000576A (es) 2012-07-20
CN102612514B (zh) 2016-01-13
US20120202877A1 (en) 2012-08-09
JP2012532894A (ja) 2012-12-20
EP2454248A4 (en) 2013-04-03
CA2768081A1 (en) 2011-01-20
EP2454248A1 (en) 2012-05-23
WO2011006208A1 (en) 2011-01-20
AU2010273184A1 (en) 2012-03-01
SG177633A1 (en) 2012-02-28
RU2012105073A (ru) 2013-08-27

Similar Documents

Publication Publication Date Title
AU2010273184B2 (en) Anti -influenza agents
JP5095066B2 (ja) 多価ノイラミニダーゼ阻害物質複合体
AU2020288770B2 (en) Saponin conjugate and vaccine or pharmaceutical composition comprising the same
US8093227B2 (en) Monosaccharide compounds and methods therefor
CA2535800A1 (en) Novel sulfenamide oxides
CA2535802A1 (en) Novel sulfenamides
ITMI20092071A1 (it) Analoghi chimerici
WO2011000721A1 (en) Inhibitors of microbial infections
US20050124559A1 (en) Antimicrobial agent
WO2006037185A1 (en) Novel sulfenamides and sulfenamide oxides
JP2005531565A (ja) 抗菌剤
AU2004266177A1 (en) Novel sulfenamides
EP3039029B1 (en) Multivalent sialic acid derivates
AU2001295282B2 (en) Combinatorial libraries of monosaccharides
AU2004266176A1 (en) Novel sulfenamide oxides
AU2003225343A1 (en) An antimicrobial agent
AU2003246615A1 (en) An antimicrobial agent
JP2009215206A (ja) シアリルα（２→６）ラクトース含有化合物及びその使用

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired