CA2755301C - Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy - Google Patents

Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy Download PDF

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Publication number
CA2755301C
CA2755301C CA2755301A CA2755301A CA2755301C CA 2755301 C CA2755301 C CA 2755301C CA 2755301 A CA2755301 A CA 2755301A CA 2755301 A CA2755301 A CA 2755301A CA 2755301 C CA2755301 C CA 2755301C
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Prior art keywords
biomarkers
expression
biomarker
extent
subject
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CA2755301A
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English (en)
French (fr)
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CA2755301A1 (en
Inventor
Robert T. Streeper
Elzbieta Izbicka
Sung H. Baek
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Cancer Prevention and Cure Ltd
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Cancer Prevention and Cure Ltd
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Priority claimed from US12/403,369 external-priority patent/US8541183B2/en
Application filed by Cancer Prevention and Cure Ltd filed Critical Cancer Prevention and Cure Ltd
Priority to CA3024643A priority Critical patent/CA3024643C/en
Publication of CA2755301A1 publication Critical patent/CA2755301A1/en
Application granted granted Critical
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486Metalloendopeptidases (3.4.24)
    • G01N2333/96491Metalloendopeptidases (3.4.24) with definite EC number
    • G01N2333/96494Matrix metalloproteases, e. g. 3.4.24.7
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2755301A 2009-03-12 2010-03-12 Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy Active CA2755301C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3024643A CA3024643C (en) 2009-03-12 2010-03-12 Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12/403,369 2009-03-12
US12/403,369 US8541183B2 (en) 2007-09-11 2009-03-12 Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof
US23719809P 2009-08-26 2009-08-26
US61/237,198 2009-08-26
PCT/US2010/027243 WO2010105235A2 (en) 2009-03-12 2010-03-12 Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3024643A Division CA3024643C (en) 2009-03-12 2010-03-12 Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy

Publications (2)

Publication Number Publication Date
CA2755301A1 CA2755301A1 (en) 2010-09-16
CA2755301C true CA2755301C (en) 2019-01-08

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Family Applications (2)

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CA2755301A Active CA2755301C (en) 2009-03-12 2010-03-12 Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy
CA3024643A Active CA3024643C (en) 2009-03-12 2010-03-12 Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy

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Country Status (10)

Country Link
US (1) US11474104B2 (https=)
EP (4) EP3444359A1 (https=)
JP (7) JP2012520469A (https=)
KR (2) KR102061441B1 (https=)
CN (4) CN108181457B (https=)
AU (3) AU2010223911A1 (https=)
CA (2) CA2755301C (https=)
ES (1) ES2703714T3 (https=)
PL (1) PL3257953T3 (https=)
WO (1) WO2010105235A2 (https=)

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Also Published As

Publication number Publication date
CA2755301A1 (en) 2010-09-16
JP2018072348A (ja) 2018-05-10
EP2406401A2 (en) 2012-01-18
EP2857522A3 (en) 2015-10-14
WO2010105235A2 (en) 2010-09-16
US11474104B2 (en) 2022-10-18
PL3257953T3 (pl) 2019-05-31
AU2016228188B2 (en) 2018-01-04
JP2016006426A (ja) 2016-01-14
JP2019158890A (ja) 2019-09-19
CN108181457B (zh) 2021-03-30
EP3257953A1 (en) 2017-12-20
CN113189342A (zh) 2021-07-30
CN102405296A (zh) 2012-04-04
ES2703714T3 (es) 2019-03-12
KR101900016B1 (ko) 2018-09-20
EP2857522A2 (en) 2015-04-08
CN104535765A (zh) 2015-04-22
JP2022000650A (ja) 2022-01-04
JP2012520469A (ja) 2012-09-06
CN113189342B (zh) 2024-12-03
WO2010105235A3 (en) 2011-02-24
AU2016228188A1 (en) 2016-09-29
JP2024024128A (ja) 2024-02-21
AU2018202110A1 (en) 2018-04-19
AU2018202110B2 (en) 2020-09-03
CA3024643C (en) 2021-08-03
JP6250600B2 (ja) 2017-12-20
EP2406401A4 (en) 2013-01-09
JP6774925B2 (ja) 2020-10-28
KR20180104190A (ko) 2018-09-19
EP3444359A1 (en) 2019-02-20
CA3024643A1 (en) 2010-09-16
EP3257953B1 (en) 2018-09-26
KR102061441B1 (ko) 2019-12-31
AU2010223911A1 (en) 2011-10-06
US20180356423A1 (en) 2018-12-13
CN108181457A (zh) 2018-06-19
KR20120010229A (ko) 2012-02-02
JP2025114736A (ja) 2025-08-05

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