CA2752518A1 - Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates - Google Patents

Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates Download PDF

Info

Publication number
CA2752518A1
CA2752518A1 CA2752518A CA2752518A CA2752518A1 CA 2752518 A1 CA2752518 A1 CA 2752518A1 CA 2752518 A CA2752518 A CA 2752518A CA 2752518 A CA2752518 A CA 2752518A CA 2752518 A1 CA2752518 A1 CA 2752518A1
Authority
CA
Canada
Prior art keywords
compound
formula
reaction
solution
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2752518A
Other languages
English (en)
French (fr)
Inventor
Max Rey (Deceased)
Thomas Otten
Daniel Korey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Biopharmaceuticals Co Ltd
Original Assignee
SK Biopharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SK Biopharmaceuticals Co Ltd filed Critical SK Biopharmaceuticals Co Ltd
Priority claimed from CA002681964A external-priority patent/CA2681964A1/en
Publication of CA2752518A1 publication Critical patent/CA2752518A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2752518A 2001-12-21 2002-12-19 Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates Abandoned CA2752518A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP01205097.7 2001-12-21
EP01205097 2001-12-21
US41808402P 2002-10-11 2002-10-11
US60/418,084 2002-10-11
CA002681964A CA2681964A1 (en) 2001-12-21 2002-12-19 Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002681964A Division CA2681964A1 (en) 2001-12-21 2002-12-19 Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates

Publications (1)

Publication Number Publication Date
CA2752518A1 true CA2752518A1 (en) 2003-07-03

Family

ID=35519523

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2752518A Abandoned CA2752518A1 (en) 2001-12-21 2002-12-19 Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates

Country Status (5)

Country Link
KR (2) KR20100134082A (ko)
CN (1) CN101343243A (ko)
CA (1) CA2752518A1 (ko)
EA (1) EA007741B1 (ko)
ZA (1) ZA200405782B (ko)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504108A (en) * 1990-01-12 1996-04-02 The Ohio State University Research Foundation Optically pure 4-aryl-2-hydroxytetronic acids
JP3010497B2 (ja) * 1990-05-31 2000-02-21 チッソ株式会社 光学活性α―ヒドロキシエステル類の製造方法
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
JP3960801B2 (ja) * 1999-11-29 2007-08-15 三菱レイヨン株式会社 アセタールスルホネート誘導体およびその製造方法ならびにスチレンオキサイド誘導体の製造方法

Also Published As

Publication number Publication date
CN101343243A (zh) 2009-01-14
KR20040068588A (ko) 2004-07-31
KR20100134082A (ko) 2010-12-22
ZA200405782B (en) 2005-08-29
KR100945720B1 (ko) 2010-03-05
EA007741B1 (ru) 2006-12-29
EA200400850A1 (ru) 2004-10-28

Similar Documents

Publication Publication Date Title
KR101868166B1 (ko) 트레프로스티닐의 제조
EP2511262B1 (en) Process for producing 2-amino-2-[2-[4-(3-benzyloxy-phenylthio)-2-chlorophenyl[ethyl]-1,3-propanediol hydrochloride
AU2009212987A1 (en) Process for preparing 2-(substituted phenyl)-2-hydroxy-ethyl carbamates
JP2023526402A (ja) ブチル－（５ｓ）－５－（｛２－［４－（ブトキシカルボニル）フェニル］エチル｝［２－（２－｛［３－クロロ－４′－（トリフルオロメチル）［ビフェニル］－４－イル］メトキシ｝フェニル）エチル］アミノ）－５，６，７，８－テトラヒドロキノリン－２－カルボキシレートの製造方法
KR101308258B1 (ko) 엔독시펜의 신규한 제조 방법
CA2752518A1 (en) Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates
CN106674281B (zh) 一种瑞舒伐他汀中间体化合物、制备方法及其用途
CA2702873C (en) Improved process for preparing 2-(substituted phenyl)-2-hydroxy-ethyl carbamates
KR101134021B1 (ko) 새로운 중간체를 이용하는 피타바스타틴 헤미칼슘의 신규한 제조방법
KR20180081276A (ko) 5-(3,6-다이하이드로-2,6-다이옥소-4-트리플루오로메틸-1(2h)-피리미디닐)페닐싸이올 화합물의 제조 방법
JPH08151354A (ja) アミノアセトアミド誘導体の製造法
EP4061805A1 (en) Process for preparing chroman compounds
JP2004123640A (ja) ３−ニトロ−１，８−ナフチリジン−２（１ｈ）−オン誘導体の製造法
JPS6121623B2 (ko)
JPS5946234A (ja) 光学活性アルコ−ルの製造方法

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead

Effective date: 20131219